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Showing 5857 to 5862 of 5862 entries
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Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.

eLife

Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Herlands L, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP.
PMID: 34874007
Elife. 2021 Dec 07;10. doi: 10.7554/eLife.73027.

The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral escape. We therefore generated a large nanobody repertoire to saturate the distinct and highly conserved available epitope space...

Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany.

Journal of psychosomatic research

Sauer KS, Schmidt A, Jungmann SM, Bailer J, Witthöft M.
PMID: 34875465
J Psychosom Res. 2021 Dec 01;152:110687. doi: 10.1016/j.jpsychores.2021.110687. Epub 2021 Dec 01.

OBJECTIVE: Pre-existing health anxiety is associated with an intensified affective response to the novel COVID-19 pandemic in the general population. Still, results on the reaction of people with a diagnosis of pathological health anxiety (i.e., hypochondriasis) are scarce.METHODS: In...

Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Kommoss FKF, Stichel D, Mora J, Esteller M, Jones DTW, Pfister SM, Brack E, Wachtel M, Bode PK, Sinn HP, Schmidt D, Mentzel T, Kommoss F, Sahm F, von Deimling A, Koelsche C.
PMID: 33846547
Mod Pathol. 2021 Aug;34(8):1558-1569. doi: 10.1038/s41379-021-00804-y. Epub 2021 Apr 12.

Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently harbor DICER1 mutations. Interestingly, only rare cases of extrauterine DICER1-associated ERMS, mostly located in the genitourinary tract, have been reported to date. Our goal was to study...

Association between sports participation history and age of first exposure to high-risk sports with concussion history.

Research in sports medicine (Print)

Caccese J, Schmidt J, Moody J, Broglio S, McAllister T, McCrea M, Pasquina P, Buckley T, Investigators CC.
PMID: 34402703
Res Sports Med. 2021 Aug 17;1-13. doi: 10.1080/15438627.2021.1966008. Epub 2021 Aug 17.

The purpose of this study was to examine the association between sports participation history, including estimated age of first exposure (eAFE) to high-risk sports, and concussion history in first year (i.e., freshmen) collegiate athletes. Athletes increased their odds of...

Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals.

GMS hygiene and infection control

Nürnberger L, Schmidt D, Szumlanski T, Kirchhoff L, Ross B, Steinmann J, Rath PM.
PMID: 33796441
GMS Hyg Infect Control. 2021 Mar 17;16:Doc13. doi: 10.3205/dgkh000384. eCollection 2021.

No abstract available.

Metronomic Chemotherapy for Metastatic Breast Cancer.

Oncology research and treatment

Krajnak S, Battista MJ, Hasenburg A, Schmidt M.
PMID: 34794154
Oncol Res Treat. 2021 Nov 18;1-6. doi: 10.1159/000520236. Epub 2021 Nov 18.

BACKGROUND: As disease control and quality of life play a leading role in metastatic breast cancer (MBC), metronomic chemotherapy (MCT) is gaining popularity alongside conventional chemotherapy (CCT) and targeted therapies.SUMMARY: MCT, defined as continuous administration of low-dose chemotherapeutic agents,...

Showing 5857 to 5862 of 5862 entries