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The Inter-Rater Reliability of Pediatric Point-of-Care Lung Ultrasound Interpretation in Children with Acute Respiratory Failure.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

DeSanti RL, Cowan EA, Kory PD, Lasarev MR, Schmidt J, Al-Subu AM.
PMID: 34378821
J Ultrasound Med. 2021 Aug 11; doi: 10.1002/jum.15805. Epub 2021 Aug 11.

OBJECTIVES: Use of point-of-care lung ultrasound (POC-LUS) has increased significantly in pediatrics yet it remains under-studied in the pediatric intensive care unit (PICU). No studies explicitly evaluate the reliability of POC-LUS artifact interpretation among critically ill children with acute...

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DeSanti RL, Cowan EA, Kory PD, et al. The Inter-Rater Reliability of Pediatric Point-of-Care Lung Ultrasound Interpretation in Children with Acute Respiratory Failure. J Ultrasound Med. 2021;doi: 10.1002/jum.15805.
DeSanti, R. L., Cowan, E. A., Kory, P. D., Lasarev, M. R., Schmidt, J., & Al-Subu, A. M. (2021). The Inter-Rater Reliability of Pediatric Point-of-Care Lung Ultrasound Interpretation in Children with Acute Respiratory Failure. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, . https://doi.org/10.1002/jum.15805
DeSanti, Ryan L, et al. "The Inter-Rater Reliability of Pediatric Point-of-Care Lung Ultrasound Interpretation in Children with Acute Respiratory Failure." Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine vol. (2021). doi: https://doi.org/10.1002/jum.15805
DeSanti RL, Cowan EA, Kory PD, Lasarev MR, Schmidt J, Al-Subu AM. The Inter-Rater Reliability of Pediatric Point-of-Care Lung Ultrasound Interpretation in Children with Acute Respiratory Failure. J Ultrasound Med. 2021 Aug 11; doi: 10.1002/jum.15805. Epub 2021 Aug 11. PMID: 34378821.
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Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease.

The New England journal of medicine

Goyal S, Tisdale J, Schmidt M, Kanter J, Jaroscak J, Whitney D, Bitter H, Gregory PD, Parsons G, Foos M, Yeri A, Gioia M, Voytek SB, Miller A, Lynch J, Colvin RA, Bonner M.
PMID: 34898140
N Engl J Med. 2022 Jan 13;386(2):138-147. doi: 10.1056/NEJMoa2109167. Epub 2021 Dec 12.

Gene therapy with LentiGlobin for sickle cell disease (bb1111, lovotibeglogene autotemcel) consists of autologous transplantation of a patient's hematopoietic stem cells transduced with the BB305 lentiviral vector that encodes the β

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Goyal S, Tisdale J, Schmidt M, et al. Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease. N Engl J Med. 2021;386(2):138-147doi: 10.1056/NEJMoa2109167.
Goyal, S., Tisdale, J., Schmidt, M., Kanter, J., Jaroscak, J., Whitney, D., Bitter, H., Gregory, P. D., Parsons, G., Foos, M., Yeri, A., Gioia, M., Voytek, S. B., Miller, A., Lynch, J., Colvin, R. A., & Bonner, M. (2022). Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease. The New England journal of medicine, 386(2), 138-147. https://doi.org/10.1056/NEJMoa2109167
Goyal, Sunita, et al. "Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease." The New England journal of medicine vol. 386,2 (2022): 138-147. doi: https://doi.org/10.1056/NEJMoa2109167
Goyal S, Tisdale J, Schmidt M, Kanter J, Jaroscak J, Whitney D, Bitter H, Gregory PD, Parsons G, Foos M, Yeri A, Gioia M, Voytek SB, Miller A, Lynch J, Colvin RA, Bonner M. Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease. N Engl J Med. 2022 Jan 13;386(2):138-147. doi: 10.1056/NEJMoa2109167. Epub 2021 Dec 12. PMID: 34898140.
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Determining Acceptance of e-Mental Health Interventions in Digital Psychodiabetology Using a Quantitative Web-Based Survey: Cross-sectional Study.

JMIR formative research

Damerau M, Teufel M, Musche V, Dinse H, Schweda A, Beckord J, Steinbach J, Schmidt K, Skoda EM, Bäuerle A.
PMID: 34328429
JMIR Form Res. 2021 Jul 30;5(7):e27436. doi: 10.2196/27436.

BACKGROUND: Diabetes is a very common chronic disease that exerts massive physiological and psychological burdens on patients. The digitalization of mental health care has generated effective e-mental health approaches, which offer an indubitable practical value for patient treatment. However,...

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Damerau M, Teufel M, Musche V, et al. Determining Acceptance of e-Mental Health Interventions in Digital Psychodiabetology Using a Quantitative Web-Based Survey: Cross-sectional Study. JMIR Form Res. 2021;5(7):e27436doi: 10.2196/27436.
Damerau, M., Teufel, M., Musche, V., Dinse, H., Schweda, A., Beckord, J., Steinbach, J., Schmidt, K., Skoda, E. M., & Bäuerle, A. (2021). Determining Acceptance of e-Mental Health Interventions in Digital Psychodiabetology Using a Quantitative Web-Based Survey: Cross-sectional Study. JMIR formative research, 5(7), e27436. https://doi.org/10.2196/27436
Damerau, Mirjam, et al. "Determining Acceptance of e-Mental Health Interventions in Digital Psychodiabetology Using a Quantitative Web-Based Survey: Cross-sectional Study." JMIR formative research vol. 5,7 (2021): e27436. doi: https://doi.org/10.2196/27436
Damerau M, Teufel M, Musche V, Dinse H, Schweda A, Beckord J, Steinbach J, Schmidt K, Skoda EM, Bäuerle A. Determining Acceptance of e-Mental Health Interventions in Digital Psychodiabetology Using a Quantitative Web-Based Survey: Cross-sectional Study. JMIR Form Res. 2021 Jul 30;5(7):e27436. doi: 10.2196/27436. PMID: 34328429; PMCID: PMC8367156.
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The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System.

Biomedicines

Schmidt C, Weißmüller S, Bohländer F, Germer M, König M, Staus A, Wartenberg-Demand A, Heinz CC, Schüttrumpf J.
PMID: 34356880
Biomedicines. 2021 Jul 14;9(7). doi: 10.3390/biomedicines9070817.

Activation of the complement system is important for efficient clearance of a wide variety of pathogens via opsonophagocytosis, or by direct lysis via complement-dependent cytotoxicity (CDC). However, in severe infections dysregulation of the complement system contributes to hyperinflammation. The...

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Schmidt C, Weißmüller S, Bohländer F, et al. The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System. Biomedicines. 2021;9(7)doi: 10.3390/biomedicines9070817.
Schmidt, C., Weißmüller, S., Bohländer, F., Germer, M., König, M., Staus, A., Wartenberg-Demand, A., Heinz, C. C., & Schüttrumpf, J. (2021). The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System. Biomedicines, 9(7), . https://doi.org/10.3390/biomedicines9070817
Schmidt, Carolin, et al. "The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System." Biomedicines vol. 9,7 (2021). doi: https://doi.org/10.3390/biomedicines9070817
Schmidt C, Weißmüller S, Bohländer F, Germer M, König M, Staus A, Wartenberg-Demand A, Heinz CC, Schüttrumpf J. The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System. Biomedicines. 2021 Jul 14;9(7). doi: 10.3390/biomedicines9070817. PMID: 34356880; PMCID: PMC8301464.
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Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in .

Frontiers in immunology

Anim M, Sogkas G, Schmidt G, Dubrowinskaja N, Witte T, Schmidt RE, Atschekzei F.
PMID: 35003082
Front Immunol. 2021 Dec 24;12:767188. doi: 10.3389/fimmu.2021.767188. eCollection 2021.

NF-κB1 deficiency is suggested to be the most common cause of common variable immunodeficiency (CVID).

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Anim M, Sogkas G, Schmidt G, et al. Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in . Front Immunol. 2021;12:767188doi: 10.3389/fimmu.2021.767188.
Anim, M., Sogkas, G., Schmidt, G., Dubrowinskaja, N., Witte, T., Schmidt, R. E., & Atschekzei, F. (2021). Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in . Frontiers in immunology, 12767188. https://doi.org/10.3389/fimmu.2021.767188
Anim, Manfred, et al. "Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in ." Frontiers in immunology vol. 12 (2021): 767188. doi: https://doi.org/10.3389/fimmu.2021.767188
Anim M, Sogkas G, Schmidt G, Dubrowinskaja N, Witte T, Schmidt RE, Atschekzei F. Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in . Front Immunol. 2021 Dec 24;12:767188. doi: 10.3389/fimmu.2021.767188. eCollection 2021. PMID: 35003082; PMCID: PMC8738076.
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Inhibition of Candida albicans by Fluvastatin Is Dependent on pH.

Research letters in biochemistry

Schmidt M, Dzogbeta S, Boyer MP.
PMID: 22820748
Res Lett Biochem. 2009;2009:151424. doi: 10.1155/2009/151424. Epub 2009 Aug 05.

The cholesterol-lowering drug fluvastatin (FS) has an inhibitory effect on the growth of the pathogenic yeast Candida albicans that is dependent on the pH of the medium. At the low pH value of the vagina, FS is growth inhibitory...

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Schmidt M, Dzogbeta S, Boyer MP. Inhibition of Candida albicans by Fluvastatin Is Dependent on pH. Res Lett Biochem. 2009;2009:151424doi: 10.1155/2009/151424.
Schmidt, M., Dzogbeta, S., & Boyer, M. P. (2009). Inhibition of Candida albicans by Fluvastatin Is Dependent on pH. Research letters in biochemistry, 2009151424. https://doi.org/10.1155/2009/151424
Schmidt, Martin, et al. "Inhibition of Candida albicans by Fluvastatin Is Dependent on pH." Research letters in biochemistry vol. 2009 (2009): 151424. doi: https://doi.org/10.1155/2009/151424
Schmidt M, Dzogbeta S, Boyer MP. Inhibition of Candida albicans by Fluvastatin Is Dependent on pH. Res Lett Biochem. 2009;2009:151424. doi: 10.1155/2009/151424. Epub 2009 Aug 05. PMID: 22820748; PMCID: PMC3005803.
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Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.

eLife

Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Herlands L, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP.
PMID: 34874007
Elife. 2021 Dec 07;10. doi: 10.7554/eLife.73027.

The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral escape. We therefore generated a large nanobody repertoire to saturate the distinct and highly conserved available epitope space...

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Mast FD, Fridy PC, Ketaren NE, et al. Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape. Elife. 2021;10doi: 10.7554/eLife.73027.
Mast, F. D., Fridy, P. C., Ketaren, N. E., Wang, J., Jacobs, E. Y., Olivier, J. P., Sanyal, T., Molloy, K. R., Schmidt, F., Rutkowska, M., Weisblum, Y., Rich, L. M., Vanderwall, E. R., Dambrauskas, N., Vigdorovich, V., Keegan, S., Jiler, J. B., Stein, M. E., Olinares, P. D. B., Herlands, L., Hatziioannou, T., Sather, D. N., Debley, J. S., Fenyö, D., Sali, A., Bieniasz, P. D., Aitchison, J. D., Chait, B. T., & Rout, M. P. (2021). Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape. eLife, 10. https://doi.org/10.7554/eLife.73027
Mast, Fred D, et al. "Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape." eLife vol. 10 (2021). doi: https://doi.org/10.7554/eLife.73027
Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Herlands L, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP. Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape. Elife. 2021 Dec 07;10. doi: 10.7554/eLife.73027. PMID: 34874007; PMCID: PMC8651292.
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Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany.

Journal of psychosomatic research

Sauer KS, Schmidt A, Jungmann SM, Bailer J, Witthöft M.
PMID: 34875465
J Psychosom Res. 2021 Dec 01;152:110687. doi: 10.1016/j.jpsychores.2021.110687. Epub 2021 Dec 01.

OBJECTIVE: Pre-existing health anxiety is associated with an intensified affective response to the novel COVID-19 pandemic in the general population. Still, results on the reaction of people with a diagnosis of pathological health anxiety (i.e., hypochondriasis) are scarce.METHODS: In...

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Sauer KS, Schmidt A, Jungmann SM, et al. Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany. J Psychosom Res. 2021;152:110687doi: 10.1016/j.jpsychores.2021.110687.
Sauer, K. S., Schmidt, A., Jungmann, S. M., Bailer, J., & Witthöft, M. (2021). Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany. Journal of psychosomatic research, 152110687. https://doi.org/10.1016/j.jpsychores.2021.110687
Sauer, Karoline S, et al. "Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany." Journal of psychosomatic research vol. 152 (2021): 110687. doi: https://doi.org/10.1016/j.jpsychores.2021.110687
Sauer KS, Schmidt A, Jungmann SM, Bailer J, Witthöft M. Do patients with pathological health anxiety fear COVID-19? A time-course analysis of 12 single cases during the "first wave" of the COVID-19 pandemic in Germany. J Psychosom Res. 2021 Dec 01;152:110687. doi: 10.1016/j.jpsychores.2021.110687. Epub 2021 Dec 01. PMID: 34875465; PMCID: PMC8632435.
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Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Kommoss FKF, Stichel D, Mora J, Esteller M, Jones DTW, Pfister SM, Brack E, Wachtel M, Bode PK, Sinn HP, Schmidt D, Mentzel T, Kommoss F, Sahm F, von Deimling A, Koelsche C.
PMID: 33846547
Mod Pathol. 2021 Aug;34(8):1558-1569. doi: 10.1038/s41379-021-00804-y. Epub 2021 Apr 12.

Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently harbor DICER1 mutations. Interestingly, only rare cases of extrauterine DICER1-associated ERMS, mostly located in the genitourinary tract, have been reported to date. Our goal was to study...

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Kommoss FKF, Stichel D, Mora J, et al. Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup. Mod Pathol. 2021;34(8):1558-1569doi: 10.1038/s41379-021-00804-y.
Kommoss, F. K. F., Stichel, D., Mora, J., Esteller, M., Jones, D. T. W., Pfister, S. M., Brack, E., Wachtel, M., Bode, P. K., Sinn, H. P., Schmidt, D., Mentzel, T., Kommoss, F., Sahm, F., von Deimling, A., & Koelsche, C. (2021). Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 34(8), 1558-1569. https://doi.org/10.1038/s41379-021-00804-y
Kommoss, Felix K F, et al. "Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc vol. 34,8 (2021): 1558-1569. doi: https://doi.org/10.1038/s41379-021-00804-y
Kommoss FKF, Stichel D, Mora J, Esteller M, Jones DTW, Pfister SM, Brack E, Wachtel M, Bode PK, Sinn HP, Schmidt D, Mentzel T, Kommoss F, Sahm F, von Deimling A, Koelsche C. Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup. Mod Pathol. 2021 Aug;34(8):1558-1569. doi: 10.1038/s41379-021-00804-y. Epub 2021 Apr 12. PMID: 33846547; PMCID: PMC8295035.
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Association between sports participation history and age of first exposure to high-risk sports with concussion history.

Research in sports medicine (Print)

Caccese J, Schmidt J, Moody J, Broglio S, McAllister T, McCrea M, Pasquina P, Buckley T, Investigators CC.
PMID: 34402703
Res Sports Med. 2021 Aug 17;1-13. doi: 10.1080/15438627.2021.1966008. Epub 2021 Aug 17.

The purpose of this study was to examine the association between sports participation history, including estimated age of first exposure (eAFE) to high-risk sports, and concussion history in first year (i.e., freshmen) collegiate athletes. Athletes increased their odds of...

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Caccese J, Schmidt J, Moody J, et al. Association between sports participation history and age of first exposure to high-risk sports with concussion history. Res Sports Med. 2021;1-13doi: 10.1080/15438627.2021.1966008.
Caccese, J., Schmidt, J., Moody, J., Broglio, S., McAllister, T., McCrea, M., Pasquina, P., Buckley, T., & Investigators, C. C. (2021). Association between sports participation history and age of first exposure to high-risk sports with concussion history. Research in sports medicine (Print), 1-13. https://doi.org/10.1080/15438627.2021.1966008
Caccese, Jaclyn, et al. "Association between sports participation history and age of first exposure to high-risk sports with concussion history." Research in sports medicine (Print) vol. (2021): 1-13. doi: https://doi.org/10.1080/15438627.2021.1966008
Caccese J, Schmidt J, Moody J, Broglio S, McAllister T, McCrea M, Pasquina P, Buckley T, Investigators CC. Association between sports participation history and age of first exposure to high-risk sports with concussion history. Res Sports Med. 2021 Aug 17;1-13. doi: 10.1080/15438627.2021.1966008. Epub 2021 Aug 17. PMID: 34402703.
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Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals.

GMS hygiene and infection control

Nürnberger L, Schmidt D, Szumlanski T, Kirchhoff L, Ross B, Steinmann J, Rath PM.
PMID: 33796441
GMS Hyg Infect Control. 2021 Mar 17;16:Doc13. doi: 10.3205/dgkh000384. eCollection 2021.

No abstract available.

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Nürnberger L, Schmidt D, Szumlanski T, et al. Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals. GMS Hyg Infect Control. 2021;16:Doc13doi: 10.3205/dgkh000384.
Nürnberger, L., Schmidt, D., Szumlanski, T., Kirchhoff, L., Ross, B., Steinmann, J., & Rath, P. M. (2021). Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals. GMS hygiene and infection control, 16Doc13. https://doi.org/10.3205/dgkh000384
Nürnberger, Laura, et al. "Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals." GMS hygiene and infection control vol. 16 (2021): Doc13. doi: https://doi.org/10.3205/dgkh000384
Nürnberger L, Schmidt D, Szumlanski T, Kirchhoff L, Ross B, Steinmann J, Rath PM. Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from two German hospitals. GMS Hyg Infect Control. 2021 Mar 17;16:Doc13. doi: 10.3205/dgkh000384. eCollection 2021. PMID: 33796441; PMCID: PMC7983015.
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Metronomic Chemotherapy for Metastatic Breast Cancer.

Oncology research and treatment

Krajnak S, Battista MJ, Hasenburg A, Schmidt M.
PMID: 34794154
Oncol Res Treat. 2021 Nov 18;1-6. doi: 10.1159/000520236. Epub 2021 Nov 18.

BACKGROUND: As disease control and quality of life play a leading role in metastatic breast cancer (MBC), metronomic chemotherapy (MCT) is gaining popularity alongside conventional chemotherapy (CCT) and targeted therapies.SUMMARY: MCT, defined as continuous administration of low-dose chemotherapeutic agents,...

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Krajnak S, Battista MJ, Hasenburg A, et al. Metronomic Chemotherapy for Metastatic Breast Cancer. Oncol Res Treat. 2021;1-6doi: 10.1159/000520236.
Krajnak, S., Battista, M. J., Hasenburg, A., & Schmidt, M. (2021). Metronomic Chemotherapy for Metastatic Breast Cancer. Oncology research and treatment, 1-6. https://doi.org/10.1159/000520236
Krajnak, Slavomir, et al. "Metronomic Chemotherapy for Metastatic Breast Cancer." Oncology research and treatment vol. (2021): 1-6. doi: https://doi.org/10.1159/000520236
Krajnak S, Battista MJ, Hasenburg A, Schmidt M. Metronomic Chemotherapy for Metastatic Breast Cancer. Oncol Res Treat. 2021 Nov 18;1-6. doi: 10.1159/000520236. Epub 2021 Nov 18. PMID: 34794154.
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