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Showing 637 to 643 of 643 entries
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Chaperonin Abundance Enhances Bacterial Fitness.

Frontiers in molecular biosciences

Kumar CMS, Chugh K, Dutta A, Mahamkali V, Bose T, Mande SS, Mande SC, Lund PA.
PMID: 34381811
Front Mol Biosci. 2021 Jul 26;8:669996. doi: 10.3389/fmolb.2021.669996. eCollection 2021.

The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in

A Trans-Governmental Collaboration to Independently Evaluate SARS-CoV-2 Serology Assays.

Microbiology spectrum

Pinto LA, Shawar RM, O'Leary B, Kemp TJ, Cherry J, Thornburg N, Miller CN, Gallagher PS, Stenzel T, Schuck B, Owen SM, Kondratovich M, Satheshkumar PS, Schuh A, Lester S, Cassetti MC, Sharpless NE, Gitterman S, Lowy DR.
PMID: 35019677
Microbiol Spectr. 2022 Jan 12;e0156421. doi: 10.1128/spectrum.01564-21. Epub 2022 Jan 12.

The emergence of SARS-CoV-2 created a crucial need for serology assays to detect anti-SARS-CoV-2 antibodies, which led to many serology assays entering the market. A trans-government collaboration was created in April 2020 to independently evaluate the performance of commercial...

Evaluating the Effectiveness of a One-Week Multimodal Prevention Program for Slowing down and Stress Reduction Performed in a German Health Resort: Results of a Randomized Controlled Trial.

Complementary medicine research

Kus S, Immich G, Oberhauser C, Frisch D, Schuh A.
PMID: 33951633
Complement Med Res. 2021 May 05;1-11. doi: 10.1159/000516025. Epub 2021 May 05.

BACKGROUND: Effective concepts are required to overcome the negative impact of daily stressful overwhelming. We investigated the effectiveness of a 1-week multimodal program for stress reduction.METHODS: We performed a randomized controlled trial including adults with above-average stress level. The...

A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.

European journal of immunology

Peter AS, Roth E, Schulz SR, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Grüner E, Peterhoff D, Ciesek S, Hoffmann M, Pöhlmann S, McKay PF, Shattock RJ, Wölfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler TH, Grunwald T, Überla K, Jäck HM.
PMID: 34355795
Eur J Immunol. 2021 Aug 06; doi: 10.1002/eji.202149374. Epub 2021 Aug 06.

TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly isolate human monoclonal antibodies. After immunizing these mice with DNA encoding the spike protein of SARS-CoV-2 and boosting with...

Comparing Pediatric Gastroenteritis Emergency Department Care in Canada and the United States.

Pediatrics

Freedman SB, Roskind CG, Schuh S, VanBuren JM, Norris JG, Tarr PI, Hurley K, Levine AC, Rogers A, Bhatt S, Gouin S, Mahajan P, Vance C, Powell EC, Farion KJ, Sapien R, O'Connell K, Poonai N, Schnadower D.
PMID: 34016656
Pediatrics. 2021 Jun;147(6). doi: 10.1542/peds.2020-030890. Epub 2021 May 20.

BACKGROUND: Between-country variation in health care resource use and its impact on outcomes in acute care settings have been challenging to disentangle from illness severity by using administrative data.METHODS: We conducted a preplanned analysis employing patient-level emergency department (ED)...

College student preferences of telepsychiatry.

Journal of American college health : J of ACH

Schuh W.
PMID: 33891516
J Am Coll Health. 2021 Apr 23;1-8. doi: 10.1080/07448481.2021.1908305. Epub 2021 Apr 23.

OBJECTIVE: To identify differences in preferences related to telepsychiatry among college students who have and have not been diagnosed with a mental health condition in the last year.PARTICIPANTS: Students (METHODS: A quantitative, causal-comparative design using an adapted version of...

Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly.

JCI insight

Minassian AM, Themistocleous Y, Silk SE, Barrett JR, Kemp A, Quinkert D, Nielsen CM, Edwards NJ, Rawlinson TA, Ramos Lopez F, Roobsoong W, Ellis KJ, Cho JS, Aunin E, Otto TD, Reid AJ, Bach FA, Labbé GM, Poulton ID, Marini A, Zaric M, Mulatier M, Lopez Ramon R, Baker M, Mitton CH, Sousa JC, Rachaphaew N, Kumpitak C, Maneechai N, Suansomjit C, Piteekan T, Hou MM, Khozoee B, McHugh K, Roberts DJ, Lawrie AM, Blagborough AM, Nugent FL, Taylor IJ, Johnson KJ, Spence PJ, Sattabongkot J, Biswas S, Rayner JC, Draper SJ.
PMID: 34609964
JCI Insight. 2021 Dec 08;6(23). doi: 10.1172/jci.insight.152465.

Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-characterized P. vivax parasites that are safe and suitable...

Showing 637 to 643 of 643 entries