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Showing 2881 to 2887 of 2887 entries
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ACS synthetic biology

Phaneuf PV, Zielinski DC, Yurkovich JT, Johnsen J, Szubin R, Yang L, Kim SH, Schulz S, Wu M, Dalldorf C, Ozdemir E, Lennen RM, Palsson BO, Feist AM.
PMID: 34762392
ACS Synth Biol. 2021 Dec 17;10(12):3379-3395. doi: 10.1021/acssynbio.1c00337. Epub 2021 Nov 11.

Microbes are being engineered for an increasingly large and diverse set of applications. However, the designing of microbial genomes remains challenging due to the general complexity of biological systems. Adaptive Laboratory Evolution (ALE) leverages nature's problem-solving processes to generate...

The gene regulation knowledge commons: the action area of GREEKC.

Biochimica et biophysica acta. Gene regulatory mechanisms

Kuiper M, Bonello J, Fernández-Breis JT, Bucher P, Futschik ME, Gaudet P, Kulakovskiy IV, Licata L, Logie C, Lovering RC, Makeev VJ, Orchard S, Panni S, Perfetto L, Sant D, Schulz S, Vercruysse S, Zerbino DR, Lægreid A.
PMID: 34757206
Biochim Biophys Acta Gene Regul Mech. 2021 Oct 30;1865(1):194768. doi: 10.1016/j.bbagrm.2021.194768. Epub 2021 Oct 30.

As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability and interoperability of resources. To address this, the COST...

A usable home: A qualitative investigation of the relationship between home usability and community participation for people with disabilities.

Disability and health journal

Greiman L, Koon L, Schulz JA, Nary D.
PMID: 34521605
Disabil Health J. 2022 Jan;15(1):101211. doi: 10.1016/j.dhjo.2021.101211. Epub 2021 Aug 31.

BACKGROUND: People with mobility disabilities frequently have unmet needs in their home environment, which can lead to difficulties completing daily living activities. Therefore, it is important that homes are not just accessible, but rather useable, meaning that the home...

MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening.

Molecular therapy. Nucleic acids

Schellinger IN, Wagenhäuser M, Chodisetti G, Mattern K, Dannert A, Petzold A, Jakubizka-Smorag J, Emrich F, Haunschild J, Schuster A, Schwob E, Schulz K, Maegdefessel L, Spin JM, Stumvoll M, Hasenfuß G, Tsao PS, Raaz U.
PMID: 33767915
Mol Ther Nucleic Acids. 2021 Feb 24;24:188-199. doi: 10.1016/j.omtn.2021.02.021. eCollection 2021 Jun 04.

Patients with type 2 diabetes (T2D) are threatened by excessive cardiovascular morbidity and mortality. While accelerated arterial stiffening may represent a critical mechanistic factor driving cardiovascular risk in T2D, specific therapies to contain the underlying diabetic arterial remodeling have...

Thermodynamic profile of mutual subunit control in a heteromeric receptor.

Proceedings of the National Academy of Sciences of the United States of America

Schirmeyer J, Hummert S, Eick T, Schulz E, Schwabe T, Ehrlich G, Kukaj T, Wiegand M, Sattler C, Schmauder R, Zimmer T, Kosmalla N, Münch J, Bonus M, Gohlke H, Benndorf K.
PMID: 34301910
Proc Natl Acad Sci U S A. 2021 Jul 27;118(30). doi: 10.1073/pnas.2100469118.

Cyclic nucleotide-gated (CNG) ion channels of olfactory neurons are tetrameric membrane receptors that are composed of two A2 subunits, one A4 subunit, and one B1b subunit. Each subunit carries a cyclic nucleotide-binding domain in the carboxyl terminus, and the...

A Persistent Phosphanyl-Substituted Thioketyl Radical Anion.

Angewandte Chemie (International ed. in English)

Szych LS, Pilopp Y, Bresien J, Villinger A, Rabeah J, Schulz A.
PMID: 34843637
Angew Chem Int Ed Engl. 2021 Nov 29;e202114792. doi: 10.1002/anie.202114792. Epub 2021 Nov 29.

Alkali metal salts, M

A qualitative study of work-life choices in academic internal medicine.

Byars-Winston A, Isaac C, Kaatz A, McSorley R, Schultz A, Carnes ML.
UIID-AD: 489
2014;19:29-41. doi: 10.1007/s10459-013-9457-5.

The high attrition rate of female physicians pursuing an academic medicine research career has not been examined in the context of career development theory. We explored how internal medicine residents and faculty experience their work within the context of...

Showing 2881 to 2887 of 2887 entries