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Showing 1537 to 1541 of 1541 entries
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From Anti-PD-1/PD-L1 to CTLA-4 and to MUC1-Is the Better Response to Treatment in Smokers of Cancer Patients Drug Specific?.

Journal of personalized medicine

Wang L, Liu F, Li J, Ma L, Feng H, Liu Q, Cho WC, Chen H, Chen H, Guo H, Li Z, Howard SC, Li M, Shan B, Gu W, Ji J.
PMID: 34575691
J Pers Med. 2021 Sep 13;11(9). doi: 10.3390/jpm11090914.

Whether smokers respond to anti-cancer drugs differently than non-smokers remains controversial. The objective of this study is to explore whether the better response of the smokers is specific to therapy of anti-PD-1/PD-L1, anti-checkpoint inhibitor, individual drugs on the cell...

The Emergence of Rift Valley Fever in Gedaref State Urges the Need for a Cross-Border One Health Strategy and Enforcement of the International Health Regulations.

Pathogens (Basel, Switzerland)

Ahmed A, Mahmoud I, Eldigail M, Elhassan RM, Weaver SC.
PMID: 34358035
Pathogens. 2021 Jul 13;10(7). doi: 10.3390/pathogens10070885.

This study investigated the causative agent of a haemorrhagic fever epidemic in Gedaref state, south-east Sudan. Six cases of febrile illness with haemorrhagic manifestations presented at outpatient health-clinics. Blood samples were collected from the patients and shipped to Khartoum...

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant.

bioRxiv : the preprint server for biology

Liu Y, Liu J, Johnson BA, Xia H, Ku Z, Schindewolf C, Widen SG, An Z, Weaver SC, Menachery VD, Xie X, Shi PY.
PMID: 34462752
bioRxiv. 2021 Sep 05; doi: 10.1101/2021.08.12.456173.

SARS-CoV-2 Delta variant has rapidly replaced the Alpha variant around the world. The mechanism that drives this global replacement has not been defined. Here we report that Delta spike mutation P681R plays a key role in the Alpha-to-Delta variant...

Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research.

Critical care explorations

Verhoef PA, Kannan S, Sturgill JL, Tucker EW, Morris PE, Miller AC, Sexton TR, Koyner JL, Hejal R, Brakenridge SC, Moldawer LL, Hotchkiss RS, Blood TM, Mazer MB, Bolesta S, Alexander SA, Armaignac DL, Shein SL, Jones C, Hoemann CD, Doctor A, Friess SH, Parker RI, Rotta AT, Remy KE.
PMID: 33786450
Crit Care Explor. 2021 Mar 12;3(3):e0374. doi: 10.1097/CCE.0000000000000374. eCollection 2021 Mar.

OBJECTIVES: Since the beginning of the coronavirus disease 2019 pandemic, hundreds of thousands of patients have been treated in ICUs across the globe. The severe acute respiratory syndrome-associated coronavirus 2 virus enters cells via the angiotensin-converting enzyme 2 receptor...

Impact of COVID-19 on global burn care.

Burns : journal of the International Society for Burn Injuries

Laura P, José A, Nikki A, Khaled A, Barret JP, Jeffery C, Shobha C, Jack CS, Scott C, Nadia D, Moustafa E, Liao J, Josef H, Briana H, Sunil K, Tetsuro K, Jorge LV, Gaoxing L, Hajime M, Ariel MA, Naiem M, Kiran N, Nawar A, Faustin N, Anthony O, Tom P, Liang Q, Man RS, Ingrid S, Ahmed T, Molina VLP, Shelley W, Mark F.
PMID: 34903416
Burns. 2021 Nov 17; doi: 10.1016/j.burns.2021.11.010. Epub 2021 Nov 17.

BACKGROUND: Worldwide, different strategies have been chosen to face the COVID-19-patient surge, often affecting access to health care for other patients. This observational study aimed to investigate whether the standard of burn care changed globally during the pandemic, and...

Showing 1537 to 1541 of 1541 entries