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Dietary spermidine improves cognitive function.

Cell reports

Schroeder S, Hofer SJ, Zimmermann A, Pechlaner R, Dammbrueck C, Pendl T, Marcello GM, Pogatschnigg V, Bergmann M, Müller M, Gschiel V, Ristic S, Tadic J, Iwata K, Richter G, Farzi A, Üçal M, Schäfer U, Poglitsch M, Royer P, Mekis R, Agreiter M, Tölle RC, Sótonyi P, Willeit J, Mairhofer B, Niederkofler H, Pallhuber I, Rungger G, Tilg H, Defrancesco M, Marksteiner J, Sinner F, Magnes C, Pieber TR, Holzer P, Kroemer G, Carmona-Gutierrez D, Scorrano L, Dengjel J, Madl T, Sedej S, Sigrist SJ, Rácz B, Kiechl S, Eisenberg T, Madeo F.
PMID: 33852843
Cell Rep. 2021 Apr 13;35(2):108985. doi: 10.1016/j.celrep.2021.108985.

Decreased cognitive performance is a hallmark of brain aging, but the underlying mechanisms and potential therapeutic avenues remain poorly understood. Recent studies have revealed health-protective and lifespan-extending effects of dietary spermidine, a natural autophagy-promoting polyamine. Here, we show that...

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Schroeder S, Hofer SJ, Zimmermann A, et al. Dietary spermidine improves cognitive function. Cell Rep. 2021;35(2):108985doi: 10.1016/j.celrep.2021.108985.
Schroeder, S., Hofer, S. J., Zimmermann, A., Pechlaner, R., Dammbrueck, C., Pendl, T., Marcello, G. M., Pogatschnigg, V., Bergmann, M., Müller, M., Gschiel, V., Ristic, S., Tadic, J., Iwata, K., Richter, G., Farzi, A., Üçal, M., Schäfer, U., Poglitsch, M., Royer, P., Mekis, R., Agreiter, M., Tölle, R. C., Sótonyi, P., Willeit, J., Mairhofer, B., Niederkofler, H., Pallhuber, I., Rungger, G., Tilg, H., Defrancesco, M., Marksteiner, J., Sinner, F., Magnes, C., Pieber, T. R., Holzer, P., Kroemer, G., Carmona-Gutierrez, D., Scorrano, L., Dengjel, J., Madl, T., Sedej, S., Sigrist, S. J., Rácz, B., Kiechl, S., Eisenberg, T., & Madeo, F. (2021). Dietary spermidine improves cognitive function. Cell reports, 35(2), 108985. https://doi.org/10.1016/j.celrep.2021.108985
Schroeder, Sabrina, et al. "Dietary spermidine improves cognitive function." Cell reports vol. 35,2 (2021): 108985. doi: https://doi.org/10.1016/j.celrep.2021.108985
Schroeder S, Hofer SJ, Zimmermann A, Pechlaner R, Dammbrueck C, Pendl T, Marcello GM, Pogatschnigg V, Bergmann M, Müller M, Gschiel V, Ristic S, Tadic J, Iwata K, Richter G, Farzi A, Üçal M, Schäfer U, Poglitsch M, Royer P, Mekis R, Agreiter M, Tölle RC, Sótonyi P, Willeit J, Mairhofer B, Niederkofler H, Pallhuber I, Rungger G, Tilg H, Defrancesco M, Marksteiner J, Sinner F, Magnes C, Pieber TR, Holzer P, Kroemer G, Carmona-Gutierrez D, Scorrano L, Dengjel J, Madl T, Sedej S, Sigrist SJ, Rácz B, Kiechl S, Eisenberg T, Madeo F. Dietary spermidine improves cognitive function. Cell Rep. 2021 Apr 13;35(2):108985. doi: 10.1016/j.celrep.2021.108985. PMID: 33852843.
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Methane to Methanol Conversion Facilitated by Anionic Transition Metal Centers: The Case of Fe, Ni, Pd, and Pt.

The journal of physical chemistry. A

Sader S, Miliordos E.
PMID: 33710883
J Phys Chem A. 2021 Mar 25;125(11):2364-2373. doi: 10.1021/acs.jpca.0c10577. Epub 2021 Mar 12.

Density functional theory and high-level ab initio electronic structure calculations are performed to study the mechanism of the partial oxidation of methane to methanol facilitated by the titled anionic transition metal atoms. The energy landscape for the overall reaction...

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Sader S, Miliordos E. Methane to Methanol Conversion Facilitated by Anionic Transition Metal Centers: The Case of Fe, Ni, Pd, and Pt. J Phys Chem A. 2021;125(11):2364-2373doi: 10.1021/acs.jpca.0c10577.
Sader, S., & Miliordos, E. (2021). Methane to Methanol Conversion Facilitated by Anionic Transition Metal Centers: The Case of Fe, Ni, Pd, and Pt. The journal of physical chemistry. A, 125(11), 2364-2373. https://doi.org/10.1021/acs.jpca.0c10577
Sader, Safaa, and Miliordos, Evangelos. "Methane to Methanol Conversion Facilitated by Anionic Transition Metal Centers: The Case of Fe, Ni, Pd, and Pt." The journal of physical chemistry. A vol. 125,11 (2021): 2364-2373. doi: https://doi.org/10.1021/acs.jpca.0c10577
Sader S, Miliordos E. Methane to Methanol Conversion Facilitated by Anionic Transition Metal Centers: The Case of Fe, Ni, Pd, and Pt. J Phys Chem A. 2021 Mar 25;125(11):2364-2373. doi: 10.1021/acs.jpca.0c10577. Epub 2021 Mar 12. PMID: 33710883.
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Distal versus conventional radial access for coronary angiography and intervention: Design and rationale of DISCO RADIAL study.

American heart journal

Aminian A, Sgueglia GA, Wiemer M, Gasparini GL, Kefer J, Ruzsa Z, van Leeuwen MAH, Vandeloo B, Ungureanu C, Kedev S, Iglesias JF, Leibundgut G, Ratib K, Bernat I, Barriocanal I, Borovicanin V, Saito S.
PMID: 34666014
Am Heart J. 2021 Oct 16;244:19-30. doi: 10.1016/j.ahj.2021.10.180. Epub 2021 Oct 16.

BACKGROUND: Transradial access (TRA) has become the default access method for coronary diagnostic and interventional procedures. As compared to transfemoral access, TRA has been shown to be safer, cost-effective and more patient-friendly. Radial artery occlusion (RAO) represents the most...

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Aminian A, Sgueglia GA, Wiemer M, et al. Distal versus conventional radial access for coronary angiography and intervention: Design and rationale of DISCO RADIAL study. Am Heart J. 2021;244:19-30doi: 10.1016/j.ahj.2021.10.180.
Aminian, A., Sgueglia, G. A., Wiemer, M., Gasparini, G. L., Kefer, J., Ruzsa, Z., van Leeuwen, M. A. H., Vandeloo, B., Ungureanu, C., Kedev, S., Iglesias, J. F., Leibundgut, G., Ratib, K., Bernat, I., Barriocanal, I., Borovicanin, V., & Saito, S. (2021). Distal versus conventional radial access for coronary angiography and intervention: Design and rationale of DISCO RADIAL study. American heart journal, 24419-30. https://doi.org/10.1016/j.ahj.2021.10.180
Aminian, Adel, et al. "Distal versus conventional radial access for coronary angiography and intervention: Design and rationale of DISCO RADIAL study." American heart journal vol. 244 (2021): 19-30. doi: https://doi.org/10.1016/j.ahj.2021.10.180
Aminian A, Sgueglia GA, Wiemer M, Gasparini GL, Kefer J, Ruzsa Z, van Leeuwen MAH, Vandeloo B, Ungureanu C, Kedev S, Iglesias JF, Leibundgut G, Ratib K, Bernat I, Barriocanal I, Borovicanin V, Saito S. Distal versus conventional radial access for coronary angiography and intervention: Design and rationale of DISCO RADIAL study. Am Heart J. 2021 Oct 16;244:19-30. doi: 10.1016/j.ahj.2021.10.180. Epub 2021 Oct 16. PMID: 34666014.
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A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder.

Journal of autism and developmental disorders

Juvin J, Sadeg S, Julien-Sweerts S, Zebdi R.
PMID: 33635420
J Autism Dev Disord. 2021 Feb 26; doi: 10.1007/s10803-021-04923-y. Epub 2021 Feb 26.

This systematic review investigated the effectiveness of acceptance and commitment therapy for the parents of children with autism spectrum disorder. PsychInfo, CINAHL, PubMed, Science Direct, and Psychology and Behavioral Sciences Collection were searched using the terms "acceptance and commitment",...

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Juvin J, Sadeg S, Julien-Sweerts S, et al. A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder. J Autism Dev Disord. 2021;doi: 10.1007/s10803-021-04923-y.
Juvin, J., Sadeg, S., Julien-Sweerts, S., & Zebdi, R. (2021). A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder. Journal of autism and developmental disorders, . https://doi.org/10.1007/s10803-021-04923-y
Juvin, Julie, et al. "A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder." Journal of autism and developmental disorders vol. (2021). doi: https://doi.org/10.1007/s10803-021-04923-y
Juvin J, Sadeg S, Julien-Sweerts S, Zebdi R. A Systematic Review: Acceptance and Commitment Therapy for the Parents of Children and Adolescents with Autism Spectrum Disorder. J Autism Dev Disord. 2021 Feb 26; doi: 10.1007/s10803-021-04923-y. Epub 2021 Feb 26. PMID: 33635420.
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The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Bayrakci N, Özkan G, Şakaci M, Sedef S, Erdem İ, Tuna N, Mutlu LC, Yildirim İ, Kiraz N, Erdal B, Gelgeç E, Erer A, Saraç Ö, Yavuz A, Dolap U, Hayri UB, Kocadelioğlu İ, Batmaz E.
PMID: 34990070
Ther Apher Dial. 2022 Jan 06; doi: 10.1111/1744-9987.13790. Epub 2022 Jan 06.

INTRODUCTION: The kidneys are some of the most frequently affected organs during coronavirus disease-2019 (COVID-19). This multicenter study evaluated the incidence of and risk factors for AKI in COVID-19 patients followed-up in intensive care unit, and its association with...

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Bayrakci N, Özkan G, Şakaci M, et al. The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit. Ther Apher Dial. 2022;doi: 10.1111/1744-9987.13790.
Bayrakci, N., Özkan, G., Şakaci, M., Sedef, S., Erdem, �. �., Tuna, N., Mutlu, L. C., Yildirim, �. �., Kiraz, N., Erdal, B., Gelgeç, E., Erer, A., Saraç, �. �., Yavuz, A., Dolap, U., Hayri, U. B., Kocadelioğlu, �. �., & Batmaz, E. (2022). The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, . https://doi.org/10.1111/1744-9987.13790
Bayrakci, Nergiz, et al. "The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit." Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy vol. (2022). doi: https://doi.org/10.1111/1744-9987.13790
Bayrakci N, Özkan G, Şakaci M, Sedef S, Erdem İ, Tuna N, Mutlu LC, Yildirim İ, Kiraz N, Erdal B, Gelgeç E, Erer A, Saraç Ö, Yavuz A, Dolap U, Hayri UB, Kocadelioğlu İ, Batmaz E. The incidence of acute kidney injury and its association with mortality in patients diagnosed with COVID-19 followed-up in intensive care unit. Ther Apher Dial. 2022 Jan 06; doi: 10.1111/1744-9987.13790. Epub 2022 Jan 06. PMID: 34990070.
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Antihormonal treatment associated musculoskeletal pain in women with breast cancer in the adjuvant setting.

OncoTargets and therapy

Seber S, Solmaz D, Yetisyigit T.
PMID: 27563249
Onco Targets Ther. 2016 Aug 09;9:4929-35. doi: 10.2147/OTT.S108968. eCollection 2016.

PURPOSE: Antihormonal treatment is an effective therapy in the adjuvant setting. However, musculoskeletal pain is a common adverse effect encountered in patients receiving this treatment. We aimed to evaluate the risk factors for the development of antihormonal treatment-associated musculoskeletal...

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Seber S, Solmaz D, Yetisyigit T. Antihormonal treatment associated musculoskeletal pain in women with breast cancer in the adjuvant setting. Onco Targets Ther. 2016;9:4929-35doi: 10.2147/OTT.S108968.
Seber, S., Solmaz, D., & Yetisyigit, T. (2016). Antihormonal treatment associated musculoskeletal pain in women with breast cancer in the adjuvant setting. OncoTargets and therapy, 94929-35. https://doi.org/10.2147/OTT.S108968
Seber, Selcuk, et al. "Antihormonal treatment associated musculoskeletal pain in women with breast cancer in the adjuvant setting." OncoTargets and therapy vol. 9 (2016): 4929-35. doi: https://doi.org/10.2147/OTT.S108968
Seber S, Solmaz D, Yetisyigit T. Antihormonal treatment associated musculoskeletal pain in women with breast cancer in the adjuvant setting. Onco Targets Ther. 2016 Aug 09;9:4929-35. doi: 10.2147/OTT.S108968. eCollection 2016. PMID: 27563249; PMCID: PMC4984830.
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Safety and reliability of the sealing cuff pressure of the Microcuff pediatric tracheal tube for prevention of post-extubation morbidity in children: A comparative study.

Saudi journal of anaesthesia

Al-Metwalli RR, Sadek S.
PMID: 25422605
Saudi J Anaesth. 2014 Oct;8(4):484-8. doi: 10.4103/1658-354X.140856.

OBJECTIVES: The objective of this study is to evaluate the efficacy and safety of sealing pressure as an inflation technique of the Microcuff pediatric tracheal cuffed tube.MATERIALS AND METHODS: A total of 60 children were enrolled in this study....

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Al-Metwalli RR, Sadek S. Safety and reliability of the sealing cuff pressure of the Microcuff pediatric tracheal tube for prevention of post-extubation morbidity in children: A comparative study. Saudi J Anaesth. 2014;8(4):484-8doi: 10.4103/1658-354X.140856.
Al-Metwalli, R. R., & Sadek, S. (2014). Safety and reliability of the sealing cuff pressure of the Microcuff pediatric tracheal tube for prevention of post-extubation morbidity in children: A comparative study. Saudi journal of anaesthesia, 8(4), 484-8. https://doi.org/10.4103/1658-354X.140856
Al-Metwalli, Roshdi Roshdi, and Sadek, Sayed. "Safety and reliability of the sealing cuff pressure of the Microcuff pediatric tracheal tube for prevention of post-extubation morbidity in children: A comparative study." Saudi journal of anaesthesia vol. 8,4 (2014): 484-8. doi: https://doi.org/10.4103/1658-354X.140856
Al-Metwalli RR, Sadek S. Safety and reliability of the sealing cuff pressure of the Microcuff pediatric tracheal tube for prevention of post-extubation morbidity in children: A comparative study. Saudi J Anaesth. 2014 Oct;8(4):484-8. doi: 10.4103/1658-354X.140856. PMID: 25422605; PMCID: PMC4236934.
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Differential Expression of Lipoxygenase Isoenzymes in Embryos of Germinating Barley.

Plant physiology

Holtman WL, Van Duijn G, Sedee N, Douma AC.
PMID: 12226311
Plant Physiol. 1996 Jun;111(2):569-576. doi: 10.1104/pp.111.2.569.

Expression of lipoxygenase was studied in barley (Hordeum distichum L.) embryos during germination. Total lipoxygenase activity was high in quiescent grains, dropped during the 1st d of germination, and subsequently increased to a level similar to that in quiescent...

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Holtman WL, Van Duijn G, Sedee N, et al. Differential Expression of Lipoxygenase Isoenzymes in Embryos of Germinating Barley. Plant Physiol. 1996;111(2):569-576doi: 10.1104/pp.111.2.569.
Holtman, W. L., Van Duijn, G., Sedee, N., & Douma, A. C. (1996). Differential Expression of Lipoxygenase Isoenzymes in Embryos of Germinating Barley. Plant physiology, 111(2), 569-576. https://doi.org/10.1104/pp.111.2.569
Holtman, W. L., et al. "Differential Expression of Lipoxygenase Isoenzymes in Embryos of Germinating Barley." Plant physiology vol. 111,2 (1996): 569-576. doi: https://doi.org/10.1104/pp.111.2.569
Holtman WL, Van Duijn G, Sedee N, Douma AC. Differential Expression of Lipoxygenase Isoenzymes in Embryos of Germinating Barley. Plant Physiol. 1996 Jun;111(2):569-576. doi: 10.1104/pp.111.2.569. PMID: 12226311; PMCID: PMC157868.
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Thermal Boundary Characteristics of Homo-/Heterogeneous Interfaces.

Nanomaterials (Basel, Switzerland)

Heijmans K, Pathak AD, Solano-López P, Giordano D, Nedea S, Smeulders D.
PMID: 31035519
Nanomaterials (Basel). 2019 Apr 26;9(5). doi: 10.3390/nano9050663.

The interface of two solids in contact introduces a thermal boundary resistance (TBR), which is challenging to measure from experiments. Besides, if the interface is reactive, it can form an intermediate recrystallized or amorphous region, and extra influencing phenomena...

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Heijmans K, Pathak AD, Solano-López P, et al. Thermal Boundary Characteristics of Homo-/Heterogeneous Interfaces. Nanomaterials (Basel). 2019;9(5)doi: 10.3390/nano9050663.
Heijmans, K., Pathak, A. D., Solano-López, P., Giordano, D., Nedea, S., & Smeulders, D. (2019). Thermal Boundary Characteristics of Homo-/Heterogeneous Interfaces. Nanomaterials (Basel, Switzerland), 9(5), . https://doi.org/10.3390/nano9050663
Heijmans, Koen, et al. "Thermal Boundary Characteristics of Homo-/Heterogeneous Interfaces." Nanomaterials (Basel, Switzerland) vol. 9,5 (2019). doi: https://doi.org/10.3390/nano9050663
Heijmans K, Pathak AD, Solano-López P, Giordano D, Nedea S, Smeulders D. Thermal Boundary Characteristics of Homo-/Heterogeneous Interfaces. Nanomaterials (Basel). 2019 Apr 26;9(5). doi: 10.3390/nano9050663. PMID: 31035519; PMCID: PMC6567240.
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Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells.

Cell death discovery

Cheteh EH, Sarne V, Ceder S, Bianchi J, Augsten M, Rundqvist H, Egevad L, Östman A, Wiman KG.
PMID: 32528731
Cell Death Discov. 2020 Jun 02;6:42. doi: 10.1038/s41420-020-0272-5. eCollection 2020.

Cancer-associated fibroblasts (CAFs) promote tumor growth and progression, and increase drug resistance through several mechanisms. We have investigated the effect of CAFs on the p53 response to doxorubicin in prostate cancer cells. We show that CAFs produce interleukin-6 (IL-6),...

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Cheteh EH, Sarne V, Ceder S, et al. Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells. Cell Death Discov. 2020;6:42doi: 10.1038/s41420-020-0272-5.
Cheteh, E. H., Sarne, V., Ceder, S., Bianchi, J., Augsten, M., Rundqvist, H., Egevad, L., Östman, A., & Wiman, K. G. (2020). Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells. Cell death discovery, 642. https://doi.org/10.1038/s41420-020-0272-5
Cheteh, Emarndeena H, et al. "Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells." Cell death discovery vol. 6 (2020): 42. doi: https://doi.org/10.1038/s41420-020-0272-5
Cheteh EH, Sarne V, Ceder S, Bianchi J, Augsten M, Rundqvist H, Egevad L, Östman A, Wiman KG. Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells. Cell Death Discov. 2020 Jun 02;6:42. doi: 10.1038/s41420-020-0272-5. eCollection 2020. PMID: 32528731; PMCID: PMC7265343.
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Pd-Iminocarboxylate Complexes and Their Behavior in Ethylene Polymerization.

Chemistry, an Asian journal

Deshmukh SS, Gaikwad SR, Gonnade RG, Pandole SP, Chikkali SH.
PMID: 31863706
Chem Asian J. 2020 Feb 03;15(3):398-405. doi: 10.1002/asia.201901501. Epub 2020 Jan 16.

Designing co-catalyst-free late transition metal complexes for ethylene polymerization is a challenging task at the interface of organometallic and polymer chemistry. Herein, a set of new, co-catalyst-free, single-component catalytic systems for ethylene polymerization have been unraveled. Treatment of anthranilic...

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Deshmukh SS, Gaikwad SR, Gonnade RG, et al. Pd-Iminocarboxylate Complexes and Their Behavior in Ethylene Polymerization. Chem Asian J. 2020;15(3):398-405doi: 10.1002/asia.201901501.
Deshmukh, S. S., Gaikwad, S. R., Gonnade, R. G., Pandole, S. P., & Chikkali, S. H. (2020). Pd-Iminocarboxylate Complexes and Their Behavior in Ethylene Polymerization. Chemistry, an Asian journal, 15(3), 398-405. https://doi.org/10.1002/asia.201901501
Deshmukh, Satej S, et al. "Pd-Iminocarboxylate Complexes and Their Behavior in Ethylene Polymerization." Chemistry, an Asian journal vol. 15,3 (2020): 398-405. doi: https://doi.org/10.1002/asia.201901501
Deshmukh SS, Gaikwad SR, Gonnade RG, Pandole SP, Chikkali SH. Pd-Iminocarboxylate Complexes and Their Behavior in Ethylene Polymerization. Chem Asian J. 2020 Feb 03;15(3):398-405. doi: 10.1002/asia.201901501. Epub 2020 Jan 16. PMID: 31863706.
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A taxonomy and cultural analysis of intra-hospital patient transfers.

Research in nursing & health

Rosenberg A, Campbell Britton M, Feder S, Minges K, Hodshon B, Chaudhry SI, Jenq GY, Emerson BL.
PMID: 29722043
Res Nurs Health. 2018 May 02; doi: 10.1002/nur.21875. Epub 2018 May 02.

Existing research on intra-hospital patient transitions focuses chiefly on handoffs, or exchanges of information, between clinicians. Less is known about patient transfers within hospitals, which include but extend beyond the exchange of information. Using participant observations and interviews at...

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Rosenberg A, Campbell Britton M, Feder S, et al. A taxonomy and cultural analysis of intra-hospital patient transfers. Res Nurs Health. 2018;doi: 10.1002/nur.21875.
Rosenberg, A., Campbell Britton, M., Feder, S., Minges, K., Hodshon, B., Chaudhry, S. I., Jenq, G. Y., & Emerson, B. L. (2018). A taxonomy and cultural analysis of intra-hospital patient transfers. Research in nursing & health, . https://doi.org/10.1002/nur.21875
Rosenberg, Alana, et al. "A taxonomy and cultural analysis of intra-hospital patient transfers." Research in nursing & health vol. (2018). doi: https://doi.org/10.1002/nur.21875
Rosenberg A, Campbell Britton M, Feder S, Minges K, Hodshon B, Chaudhry SI, Jenq GY, Emerson BL. A taxonomy and cultural analysis of intra-hospital patient transfers. Res Nurs Health. 2018 May 02; doi: 10.1002/nur.21875. Epub 2018 May 02. PMID: 29722043; PMCID: PMC8459627.
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