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Showing 25 to 36 of 124 entries
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Thoracolumbar spinal fractures associated with ground level falls in the elderly: An analysis of 254,486 emergency department visits.

Journal of clinical orthopaedics and trauma

Grabel ZJ, Lunati MP, Segal DN, Kukowski NR, Yoon ST, Jain A.
PMID: 32879581
J Clin Orthop Trauma. 2020 Sep-Oct;11(5):916-920. doi: 10.1016/j.jcot.2020.04.009. Epub 2020 Apr 10.

STUDY DESIGN: retrospective.OBJECTIVES: To investigate the epidemiology of elderly (age ≥65 years) patients who presented to the emergency department (ED) in the United States with thoracolumbar (TL) fractures after ground level falls.METHODS: Using the National Emergency Department Sample database,...

Cystine and Methionine Deficiency Promotes Ferroptosis by Inducing B-Cell Translocation Gene 1.

Antioxidants (Basel, Switzerland)

Cho IJ, Kim D, Kim EO, Jegal KH, Kim JK, Park SM, Zhao R, Ki SH, Kim SC, Ku SK.
PMID: 34679678
Antioxidants (Basel). 2021 Sep 28;10(10). doi: 10.3390/antiox10101543.

Ferroptosis is a type of programmed necrosis triggered by iron-dependent lipid peroxidation. We investigated the role of B-cell translocation gene 1 (BTG1) in cystine and methionine deficiency (CST/Met (-))-mediated cell death. CST/Met (-) depleted reduced and oxidized glutathione in...

Adaptive plasticity and epigenetic variation in response to warming in an Alpine plant.

Ecology and evolution

Nicotra AB, Segal DL, Hoyle GL, Schrey AW, Verhoeven KJ, Richards CL.
PMID: 25691987
Ecol Evol. 2015 Feb;5(3):634-47. doi: 10.1002/ece3.1329. Epub 2015 Jan 13.

Environmentally induced phenotypic plasticity may be a critical component of response to changing environments. We examined local differentiation and adaptive phenotypic plasticity in response to elevated temperature in half-sib lines collected across an elevation gradient for the alpine herb,...

Personality, Interpersonal Problems, and Anxiety Among Older Adults.

Psychological reports

Noel OR, Segal DL, Granier KL.
PMID: 34961375
Psychol Rep. 2021 Dec 28;332941211061697. doi: 10.1177/00332941211061697. Epub 2021 Dec 28.

INTRODUCTION: This study examined relationships between personality disorder (PD) features, Big Five personality traits, and interpersonal problems with anxiety.METHOD: Older adults (RESULTS: Anxiety was positively correlated with 13 of 14 PD scales, ranging from .23 (Narcissistic) to .61 (Depressive)....

Emulating Control Arms for Cancer Clinical Trials Using External Cohorts Created From Electronic Health Record-Derived Real-World Data.

Clinical pharmacology and therapeutics

Tan K, Bryan J, Segal B, Bellomo L, Nussbaum N, Tucker M, Torres AZ, Bennette C, Capra W, Curtis M, Miksad RA.
PMID: 34197637
Clin Pharmacol Ther. 2022 Jan;111(1):168-178. doi: 10.1002/cpt.2351. Epub 2021 Jul 31.

Electronic health record (EHR)-derived real-world data (RWD) can be sourced to create external comparator cohorts to oncology clinical trials. This exploratory study assessed whether EHR-derived patient cohorts could emulate select clinical trial control arms across multiple tumor types. The...

Genetic analysis of four consanguineous multiplex families with inflammatory bowel disease.

Gastroenterology report

Ben-Yosef N, Frampton M, Schiff ER, Daher S, Abu Baker F, Safadi R, Israeli E, Segal AW, Levine AP.
PMID: 34925849
Gastroenterol Rep (Oxf). 2021 Jul 13;9(6):521-532. doi: 10.1093/gastro/goab007. eCollection 2021 Dec.

BACKGROUND: Family studies support a genetic predisposition to inflammatory bowel diseases (IBD), but known genetic variants only partially explain the disease heritability. Families with multiple affected individuals potentially harbour rare and high-impact causal variants. Long regions of homozygosity due...

Behavioral interaction under concurrent spaced-responding, variable-interval schedules of reinforcement.

Journal of the experimental analysis of behavior

SEGAL EF.
PMID: 13749652
J Exp Anal Behav. 1961 Jul;4:263-6. doi: 10.1901/jeab.1961.4-263.

No abstract available.

Axialization of laser cooled magnesium ions in a penning trap.

Physical review letters

Powell HF, Segal DM, Thompson RC.
PMID: 12190395
Phys Rev Lett. 2002 Aug 26;89(9):093003. doi: 10.1103/PhysRevLett.89.093003. Epub 2002 Aug 12.

We report the first demonstration of the axialization of laser cooled ions in a Penning trap. Axialization involves the application of a small radial quadrupole drive which couples the cyclotron and magnetron motions. This enhances the laser cooling, allowing...

The Expanding Role of the Oncology Pharmacist.

Pharmacy (Basel, Switzerland)

Holle LM, Segal EM, Jeffers KD.
PMID: 32722357
Pharmacy (Basel). 2020 Jul 25;8(3). doi: 10.3390/pharmacy8030130.

Although oncology pharmacists have been involved in the care of cancer patients for over 50 years, the role of the oncology pharmacist continues to expand. Initially, pharmacists were primarily based within either an inpatient or outpatient pharmacy setting and...

Making sense of the cause of Crohn's - a new look at an old disease.

F1000Research

Segal AW.
PMID: 28105308
F1000Res. 2016 Oct 12;5:2510. doi: 10.12688/f1000research.9699.2. eCollection 2016.

The cause of Crohn's disease (CD) has posed a conundrum for at least a century. A large body of work coupled with recent technological advances in genome research have at last started to provide some of the answers. Initially...

Making sense of the cause of Crohn's - a new look at an old disease.

F1000Research

Segal AW.
PMID: 28105308
F1000Res. 2016 Oct 12;5:2510. doi: 10.12688/f1000research.9699.1. eCollection 2016.

The cause of Crohn's disease (CD) has posed a conundrum for at least a century. A large body of work coupled with recent technological advances in genome research have at last started to provide some of the answers. Initially...

Hepatoprotective Effect of .

Evidence-based complementary and alternative medicine : eCAM

Park SM, Kim JK, Kim EO, Jegal KH, Jung DH, Lee SG, Cho IJ, Kim S, Byun SH, Ku SK, Park CA, Lee CW, An WG, Kim SC, Zhao R.
PMID: 32695211
Evid Based Complement Alternat Med. 2020 Jul 09;2020:6761842. doi: 10.1155/2020/6761842. eCollection 2020.

No abstract available.

Showing 25 to 36 of 124 entries