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Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge.

Toxicology research

Ball T, Barber CG, Cayley A, Chilton ML, Foster R, Fowkes A, Heghes C, Hill E, Hill N, Kane S, Macmillan DS, Myden A, Newman D, Polit A, Stalford SA, Vessey JD.
PMID: 33613978
Toxicol Res (Camb). 2021 Jan 22;10(1):102-122. doi: 10.1093/toxres/tfaa099. eCollection 2021 Jan.

Adverse outcome pathways have shown themselves to be useful ways of understanding and expressing knowledge about sequences of events that lead to adverse outcomes (AOs) such as toxicity. In this paper we use the building blocks of adverse outcome...

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Ball T, Barber CG, Cayley A, et al. Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge. Toxicol Res (Camb). 2021;10(1):102-122doi: 10.1093/toxres/tfaa099.
Ball, T., Barber, C. G., Cayley, A., Chilton, M. L., Foster, R., Fowkes, A., Heghes, C., Hill, E., Hill, N., Kane, S., Macmillan, D. S., Myden, A., Newman, D., Polit, A., Stalford, S. A., & Vessey, J. D. (2021). Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge. Toxicology research, 10(1), 102-122. https://doi.org/10.1093/toxres/tfaa099
Ball, Thomas, et al. "Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge." Toxicology research vol. 10,1 (2021): 102-122. doi: https://doi.org/10.1093/toxres/tfaa099
Ball T, Barber CG, Cayley A, Chilton ML, Foster R, Fowkes A, Heghes C, Hill E, Hill N, Kane S, Macmillan DS, Myden A, Newman D, Polit A, Stalford SA, Vessey JD. Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge. Toxicol Res (Camb). 2021 Jan 22;10(1):102-122. doi: 10.1093/toxres/tfaa099. eCollection 2021 Jan. PMID: 33613978; PMCID: PMC7885198.
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Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center.

Pediatric surgery international

Salman R, Sher AC, Sammer MBK, Rodriguez JR, Shah SR, Seghers VJ.
PMID: 34999941
Pediatr Surg Int. 2022 Jan 08; doi: 10.1007/s00383-022-05061-x. Epub 2022 Jan 08.

PURPOSE: COVID-19 disease can manifest with intussusception in pediatric patients, but prevalence of abnormalities on ultrasounds performed for intussusception is uncertain. We aim to report our experience in children with COVID-19 presenting with suspected intussusception imaged with ultrasound.METHODS: Children...

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Salman R, Sher AC, Sammer MBK, et al. Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center. Pediatr Surg Int. 2022;doi: 10.1007/s00383-022-05061-x.
Salman, R., Sher, A. C., Sammer, M. B. K., Rodriguez, J. R., Shah, S. R., & Seghers, V. J. (2022). Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center. Pediatric surgery international, . https://doi.org/10.1007/s00383-022-05061-x
Salman, Rida, et al. "Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center." Pediatric surgery international vol. (2022). doi: https://doi.org/10.1007/s00383-022-05061-x
Salman R, Sher AC, Sammer MBK, Rodriguez JR, Shah SR, Seghers VJ. Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center. Pediatr Surg Int. 2022 Jan 08; doi: 10.1007/s00383-022-05061-x. Epub 2022 Jan 08. PMID: 34999941; PMCID: PMC8742661.
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Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children.

Pediatric blood & cancer

Foster JH, Sher A, Seghers V, Poston J, Wells D, Delpassand ES, Potter S, Mahajan P, Venkatramani R.
PMID: 33844446
Pediatr Blood Cancer. 2021 Jul;68(7):e29056. doi: 10.1002/pbc.29056. Epub 2021 Apr 12.

Neuroendocrine tumors (NETs) of the pancreas and midgut are extremely rare in children, and patients presenting with metastatic disease have poor survival. Given this rarity, treatments are extrapolated from guidelines for adults with NET. Recent clinical trials in adults...

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Foster JH, Sher A, Seghers V, et al. Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children. Pediatr Blood Cancer. 2021;68(7):e29056doi: 10.1002/pbc.29056.
Foster, J. H., Sher, A., Seghers, V., Poston, J., Wells, D., Delpassand, E. S., Potter, S., Mahajan, P., & Venkatramani, R. (2021). Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children. Pediatric blood & cancer, 68(7), e29056. https://doi.org/10.1002/pbc.29056
Foster, Jennifer H, et al. "Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children." Pediatric blood & cancer vol. 68,7 (2021): e29056. doi: https://doi.org/10.1002/pbc.29056
Foster JH, Sher A, Seghers V, Poston J, Wells D, Delpassand ES, Potter S, Mahajan P, Venkatramani R. Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children. Pediatr Blood Cancer. 2021 Jul;68(7):e29056. doi: 10.1002/pbc.29056. Epub 2021 Apr 12. PMID: 33844446.
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Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems.

EJNMMI physics

Peters SMB, Meyer Viol SL, van der Werf NR, de Jong N, van Velden FHP, Meeuwis A, Konijnenberg MW, Gotthardt M, de Jong HWAM, Segbers M.
PMID: 34406512
EJNMMI Phys. 2021 Aug 18;8(1):59. doi: 10.1186/s40658-021-00399-y.

No abstract available.

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Peters SMB, Meyer Viol SL, van der Werf NR, et al. Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems. EJNMMI Phys. 2021;8(1):59doi: 10.1186/s40658-021-00399-y.
Peters, S. M. B., Meyer Viol, S. L., van der Werf, N. R., de Jong, N., van Velden, F. H. P., Meeuwis, A., Konijnenberg, M. W., Gotthardt, M., de Jong, H. W. A. M., & Segbers, M. (2021). Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems. EJNMMI physics, 8(1), 59. https://doi.org/10.1186/s40658-021-00399-y
Peters, Steffie M B, et al. "Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems." EJNMMI physics vol. 8,1 (2021): 59. doi: https://doi.org/10.1186/s40658-021-00399-y
Peters SMB, Meyer Viol SL, van der Werf NR, de Jong N, van Velden FHP, Meeuwis A, Konijnenberg MW, Gotthardt M, de Jong HWAM, Segbers M. Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems. EJNMMI Phys. 2021 Aug 18;8(1):59. doi: 10.1186/s40658-021-00399-y. PMID: 34406512; PMCID: PMC8374010.
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Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Ophey A, Krohm F, Kalbe E, Greuel A, Drzezga A, Tittgemeyer M, Timmermann L, Jessen F, Eggers C, Maier F.
PMID: 34820745
Neurol Sci. 2021 Nov 25; doi: 10.1007/s10072-021-05734-w. Epub 2021 Nov 25.

BACKGROUND: Subjective cognitive decline (SCD) may occur very early in the course of Parkinson's disease (PD) before the onset of objective cognitive decline. Data on neural correlates and determinants of SCD in PD are rare.OBJECTIVE: The aim of the...

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Ophey A, Krohm F, Kalbe E, et al. Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurol Sci. 2021;doi: 10.1007/s10072-021-05734-w.
Ophey, A., Krohm, F., Kalbe, E., Greuel, A., Drzezga, A., Tittgemeyer, M., Timmermann, L., Jessen, F., Eggers, C., & Maier, F. (2021). Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, . https://doi.org/10.1007/s10072-021-05734-w
Ophey, Anja, et al. "Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease." Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology vol. (2021). doi: https://doi.org/10.1007/s10072-021-05734-w
Ophey A, Krohm F, Kalbe E, Greuel A, Drzezga A, Tittgemeyer M, Timmermann L, Jessen F, Eggers C, Maier F. Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurol Sci. 2021 Nov 25; doi: 10.1007/s10072-021-05734-w. Epub 2021 Nov 25. PMID: 34820745.
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Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People.

Geriatrics (Basel, Switzerland)

Koppelaar H, Kordestani-Moghadam P, Kouhkani S, Irandoust F, Segers G, de Haas L, Bantje T, van Warmerdam M.
PMID: 34210015
Geriatrics (Basel). 2021 Jun 29;6(3). doi: 10.3390/geriatrics6030066.

Falls in the geriatric population are one of the most important causes of disabilities in this age group. Its consequences impose a great deal of economic burden on health and insurance systems. This study was conducted by a multidisciplinary...

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Koppelaar H, Kordestani-Moghadam P, Kouhkani S, et al. Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People. Geriatrics (Basel). 2021;6(3)doi: 10.3390/geriatrics6030066.
Koppelaar, H., Kordestani-Moghadam, P., Kouhkani, S., Irandoust, F., Segers, G., de Haas, L., Bantje, T., & van Warmerdam, M. (2021). Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People. Geriatrics (Basel, Switzerland), 6(3), . https://doi.org/10.3390/geriatrics6030066
Koppelaar, Henk, et al. "Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People." Geriatrics (Basel, Switzerland) vol. 6,3 (2021). doi: https://doi.org/10.3390/geriatrics6030066
Koppelaar H, Kordestani-Moghadam P, Kouhkani S, Irandoust F, Segers G, de Haas L, Bantje T, van Warmerdam M. Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People. Geriatrics (Basel). 2021 Jun 29;6(3). doi: 10.3390/geriatrics6030066. PMID: 34210015; PMCID: PMC8293049.
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A dedicated paediatric [.

EJNMMI research

Cox CPW, van Assema DME, Verburg FA, Brabander T, Konijnenberg M, Segbers M.
PMID: 34279735
EJNMMI Res. 2021 Jul 19;11(1):65. doi: 10.1186/s13550-021-00812-8.

BACKGROUND: The role of 2-[METHODS: In this retrospective analysis, 102 children and 85 adults were included that underwent a diagnostic [RESULTS: Body weight demonstrated the highest coefficient of determination for the nonlinear (RCONCLUSION: Body weight has the strongest relation...

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Cox CPW, van Assema DME, Verburg FA, et al. A dedicated paediatric [. EJNMMI Res. 2021;11(1):65doi: 10.1186/s13550-021-00812-8.
Cox, C. P. W., van Assema, D. M. E., Verburg, F. A., Brabander, T., Konijnenberg, M., & Segbers, M. (2021). A dedicated paediatric [. EJNMMI research, 11(1), 65. https://doi.org/10.1186/s13550-021-00812-8
Cox, Christina P W, et al. "A dedicated paediatric [." EJNMMI research vol. 11,1 (2021): 65. doi: https://doi.org/10.1186/s13550-021-00812-8
Cox CPW, van Assema DME, Verburg FA, Brabander T, Konijnenberg M, Segbers M. A dedicated paediatric [. EJNMMI Res. 2021 Jul 19;11(1):65. doi: 10.1186/s13550-021-00812-8. PMID: 34279735; PMCID: PMC8289942.
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Development of [.

Pharmaceutics

Hooijman EL, Chalashkan Y, Ling SW, Kahyargil FF, Segbers M, Bruchertseifer F, Morgenstern A, Seimbille Y, Koolen SLW, Brabander T, de Blois E.
PMID: 34068206
Pharmaceutics. 2021 May 13;13(5). doi: 10.3390/pharmaceutics13050715.

Recently, promising results of the antitumor effects were observed in patients with metastatic castration-resistant prostate cancer treated with

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Hooijman EL, Chalashkan Y, Ling SW, et al. Development of [. Pharmaceutics. 2021;13(5)doi: 10.3390/pharmaceutics13050715.
Hooijman, E. L., Chalashkan, Y., Ling, S. W., Kahyargil, F. F., Segbers, M., Bruchertseifer, F., Morgenstern, A., Seimbille, Y., Koolen, S. L. W., Brabander, T., & de Blois, E. (2021). Development of [. Pharmaceutics, 13(5), . https://doi.org/10.3390/pharmaceutics13050715
Hooijman, Eline L, et al. "Development of [." Pharmaceutics vol. 13,5 (2021). doi: https://doi.org/10.3390/pharmaceutics13050715
Hooijman EL, Chalashkan Y, Ling SW, Kahyargil FF, Segbers M, Bruchertseifer F, Morgenstern A, Seimbille Y, Koolen SLW, Brabander T, de Blois E. Development of [. Pharmaceutics. 2021 May 13;13(5). doi: 10.3390/pharmaceutics13050715. PMID: 34068206; PMCID: PMC8153125.
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Pilot Study of Mindfulness Training on the Self-Awareness of Motor Symptoms in Parkinson's Disease - A Randomized Controlled Trial.

Frontiers in psychology

Buchwitz TM, Maier F, Greuel A, Thieken F, Steidel K, Jakobs V, Eggers C.
PMID: 34916997
Front Psychol. 2021 Nov 30;12:763350. doi: 10.3389/fpsyg.2021.763350. eCollection 2021.

No abstract available.

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Buchwitz TM, Maier F, Greuel A, et al. Pilot Study of Mindfulness Training on the Self-Awareness of Motor Symptoms in Parkinson's Disease - A Randomized Controlled Trial. Front Psychol. 2021;12:763350doi: 10.3389/fpsyg.2021.763350.
Buchwitz, T. M., Maier, F., Greuel, A., Thieken, F., Steidel, K., Jakobs, V., & Eggers, C. (2021). Pilot Study of Mindfulness Training on the Self-Awareness of Motor Symptoms in Parkinson's Disease - A Randomized Controlled Trial. Frontiers in psychology, 12763350. https://doi.org/10.3389/fpsyg.2021.763350
Buchwitz, Timo Marcel, et al. "Pilot Study of Mindfulness Training on the Self-Awareness of Motor Symptoms in Parkinson's Disease - A Randomized Controlled Trial." Frontiers in psychology vol. 12 (2021): 763350. doi: https://doi.org/10.3389/fpsyg.2021.763350
Buchwitz TM, Maier F, Greuel A, Thieken F, Steidel K, Jakobs V, Eggers C. Pilot Study of Mindfulness Training on the Self-Awareness of Motor Symptoms in Parkinson's Disease - A Randomized Controlled Trial. Front Psychol. 2021 Nov 30;12:763350. doi: 10.3389/fpsyg.2021.763350. eCollection 2021. PMID: 34916997; PMCID: PMC8670006.
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The EPA's Commitment to Children's Environmental Health: History and Current Challenges.

American journal of public health

Sullivan M, Fredrickson L, Sellers C.
PMID: 34936388
Am J Public Health. 2022 Jan;112(1):124-134. doi: 10.2105/AJPH.2021.306537.

Children's environmental health (CEH) has a 25-year history at the US Environmental Protection Agency (EPA), during which the agency has advanced CEH through research, policy, and programs that address children's special vulnerability to environmental harm. However, the Trump administration...

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Sullivan M, Fredrickson L, Sellers C. The EPA's Commitment to Children's Environmental Health: History and Current Challenges. Am J Public Health. 2022;112(1):124-134doi: 10.2105/AJPH.2021.306537.
Sullivan, M., Fredrickson, L., & Sellers, C. (2022). The EPA's Commitment to Children's Environmental Health: History and Current Challenges. American journal of public health, 112(1), 124-134. https://doi.org/10.2105/AJPH.2021.306537
Sullivan, Marianne, et al. "The EPA's Commitment to Children's Environmental Health: History and Current Challenges." American journal of public health vol. 112,1 (2022): 124-134. doi: https://doi.org/10.2105/AJPH.2021.306537
Sullivan M, Fredrickson L, Sellers C. The EPA's Commitment to Children's Environmental Health: History and Current Challenges. Am J Public Health. 2022 Jan;112(1):124-134. doi: 10.2105/AJPH.2021.306537. PMID: 34936388.
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CT imaging of esophageal foreign bodies in children: a pictorial essay.

Japanese journal of radiology

Seghers VJ, Herman Kan J, Somcio R, Sher AC, Paul Guillerman R, Sammer MBK.
PMID: 34661860
Jpn J Radiol. 2021 Oct 18; doi: 10.1007/s11604-021-01201-w. Epub 2021 Oct 18.

Foreign body (FB) ingestion is common in children, particularly from 6 months to 3 years of age. As young children may be unable to provide a clinical history and the ingestion is often unwitnessed, imaging plays an important role...

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Seghers VJ, Herman Kan J, Somcio R, et al. CT imaging of esophageal foreign bodies in children: a pictorial essay. Jpn J Radiol. 2021;doi: 10.1007/s11604-021-01201-w.
Seghers, V. J., Herman Kan, J., Somcio, R., Sher, A. C., Paul Guillerman, R., & Sammer, M. B. K. (2021). CT imaging of esophageal foreign bodies in children: a pictorial essay. Japanese journal of radiology, . https://doi.org/10.1007/s11604-021-01201-w
Seghers, Victor J, et al. "CT imaging of esophageal foreign bodies in children: a pictorial essay." Japanese journal of radiology vol. (2021). doi: https://doi.org/10.1007/s11604-021-01201-w
Seghers VJ, Herman Kan J, Somcio R, Sher AC, Paul Guillerman R, Sammer MBK. CT imaging of esophageal foreign bodies in children: a pictorial essay. Jpn J Radiol. 2021 Oct 18; doi: 10.1007/s11604-021-01201-w. Epub 2021 Oct 18. PMID: 34661860.
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Regional trends and drivers of the global methane budget.

Global change biology

Stavert AR, Saunois M, Canadell JG, Poulter B, Jackson RB, Regnier P, Lauerwald R, Raymond PA, Allen GH, Patra PK, Bergamaschi P, Bousquet P, Chandra N, Ciais P, Gustafson A, Ishizawa M, Ito A, Kleinen T, Maksyutov S, McNorton J, Melton JR, Müller J, Niwa Y, Peng S, Riley WJ, Segers A, Tian H, Tsuruta A, Yin Y, Zhang Z, Zheng B, Zhuang Q.
PMID: 34553464
Glob Chang Biol. 2022 Jan;28(1):182-200. doi: 10.1111/gcb.15901. Epub 2021 Oct 27.

The ongoing development of the Global Carbon Project (GCP) global methane (CH

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Stavert AR, Saunois M, Canadell JG, et al. Regional trends and drivers of the global methane budget. Glob Chang Biol. 2021;28(1):182-200doi: 10.1111/gcb.15901.
Stavert, A. R., Saunois, M., Canadell, J. G., Poulter, B., Jackson, R. B., Regnier, P., Lauerwald, R., Raymond, P. A., Allen, G. H., Patra, P. K., Bergamaschi, P., Bousquet, P., Chandra, N., Ciais, P., Gustafson, A., Ishizawa, M., Ito, A., Kleinen, T., Maksyutov, S., McNorton, J., Melton, J. R., Müller, J., Niwa, Y., Peng, S., Riley, W. J., Segers, A., Tian, H., Tsuruta, A., Yin, Y., Zhang, Z., Zheng, B., & Zhuang, Q. (2022). Regional trends and drivers of the global methane budget. Global change biology, 28(1), 182-200. https://doi.org/10.1111/gcb.15901
Stavert, Ann R, et al. "Regional trends and drivers of the global methane budget." Global change biology vol. 28,1 (2022): 182-200. doi: https://doi.org/10.1111/gcb.15901
Stavert AR, Saunois M, Canadell JG, Poulter B, Jackson RB, Regnier P, Lauerwald R, Raymond PA, Allen GH, Patra PK, Bergamaschi P, Bousquet P, Chandra N, Ciais P, Gustafson A, Ishizawa M, Ito A, Kleinen T, Maksyutov S, McNorton J, Melton JR, Müller J, Niwa Y, Peng S, Riley WJ, Segers A, Tian H, Tsuruta A, Yin Y, Zhang Z, Zheng B, Zhuang Q. Regional trends and drivers of the global methane budget. Glob Chang Biol. 2022 Jan;28(1):182-200. doi: 10.1111/gcb.15901. Epub 2021 Oct 27. PMID: 34553464.
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Showing 25 to 36 of 226 entries