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Showing 109 to 113 of 113 entries
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Engineered materials for organoid systems.

Nature reviews. Materials

Kratochvil MJ, Seymour AJ, Li TL, Paşca SP, Kuo CJ, Heilshorn SC.
PMID: 33552558
Nat Rev Mater. 2019 Sep;4(9):606-622. doi: 10.1038/s41578-019-0129-9. Epub 2019 Aug 16.

Organoids are 3D cell culture systems that mimic some of the structural and functional characteristics of an organ. Organoid cultures provide the opportunity to study organ-level biology in models that mimic human physiology more closely than 2D cell culture...

CHH Methylation Islands: A Nonconserved Feature of Grass Genomes That Is Positively Associated with Transposable Elements but Negatively Associated with Gene-Body Methylation.

Genome biology and evolution

Martin GT, Seymour DK, Gaut BS.
PMID: 34146109
Genome Biol Evol. 2021 Aug 03;13(8). doi: 10.1093/gbe/evab144.

Methylated CHH (mCHH) islands are peaks of CHH methylation that occur primarily upstream to genes. These regions are actively targeted by the methylation machinery, occur at boundaries between heterochromatin and euchromatin, and tend to be near highly expressed genes....

Plant shade enhances thermoregulation of internal environments in Trinervitermes trinervoides mounds.

Journal of thermal biology

Ndlovu M, Nampa G, Joseph GS, Seymour CL.
PMID: 34503805
J Therm Biol. 2021 Aug;100:103068. doi: 10.1016/j.jtherbio.2021.103068. Epub 2021 Aug 04.

Microhabitats may be crucial in buffering organisms from temperature extremes, particularly given increases in maximum temperature associated with global climate change. For example, thermoregulation in termite mounds is influenced by prevailing ambient conditions, and plant canopies may reduce external...

Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.

Hepatology (Baltimore, Md.)

Alexopoulos AS, Crowley MJ, Wang Y, Moylan CA, Guy CD, Henao R, Piercy DL, Seymour KA, Sudan R, Portenier DD, Diehl AM, Coviello AD, Abdelmalek MF.
PMID: 33724511
Hepatology. 2021 Sep;74(3):1220-1233. doi: 10.1002/hep.31806. Epub 2021 Jun 02.

BACKGROUND AND AIMS: Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the...

Impact of Bamlanivimab Monoclonal Antibody Treatment on Hospitalization and Mortality Among Nonhospitalized Adults With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Open forum infectious diseases

Bariola JR, McCreary EK, Wadas RJ, Kip KE, Marroquin OC, Minnier T, Koscumb S, Collins K, Schmidhofer M, Shovel JA, Wisniewski MK, Sullivan C, Yealy DM, Nace DA, Huang DT, Haidar G, Khadem T, Linstrum K, Seymour CW, Montgomery SK, Angus DC, Snyder GM.
PMID: 34250192
Open Forum Infect Dis. 2021 May 17;8(7):ofab254. doi: 10.1093/ofid/ofab254. eCollection 2021 Jul.

BACKGROUND: Monoclonal antibody treatment may prevent complications of coronavirus disease 2019 (COVID-19). We sought to quantify the impact of bamlanivimab monoclonal antibody monotherapy on hospitalization and mortality among outpatients at high risk of COVID-19 complications.METHODS: In this observational study...

Showing 109 to 113 of 113 entries