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Showing 25 to 36 of 226 entries
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Genome Sequence of Peacock Reveals the Peculiar Case of a Glittering Bird.

Frontiers in genetics

Jaiswal SK, Gupta A, Saxena R, Prasoodanan VPK, Sharma AK, Mittal P, Roy A, Shafer ABA, Vijay N, Sharma VK.
PMID: 30283495
Front Genet. 2018 Sep 19;9:392. doi: 10.3389/fgene.2018.00392. eCollection 2018.

The unique ornamental features and extreme sexual traits of Peacock have always intrigued scientists and naturalists for centuries. However, the genomic basis of these phenotypes are yet unknown. Here, we report the first genome sequence and comparative analysis of...

Validity and Reliability of the Polar A300's Fitness Test Feature to Predict VO2max.

International journal of exercise science

Cooper KD, Shafer AB.
PMID: 30899351
Int J Exerc Sci. 2019 Mar 01;12(4):393-401. eCollection 2019.

The Polar A300 fitness watch includes a feature termed the 5-minute fitness test. This feature claims to estimate maximal oxygen consumption (VO2max) in healthy adults. The purpose of this study was to assess the validity and reliability of the...

AI4People-An Ethical Framework for a Good AI Society: Opportunities, Risks, Principles, and Recommendations.

Minds and machines

Floridi L, Cowls J, Beltrametti M, Chatila R, Chazerand P, Dignum V, Luetge C, Madelin R, Pagallo U, Rossi F, Schafer B, Valcke P, Vayena E.
PMID: 30930541
Minds Mach (Dordr). 2018;28(4):689-707. doi: 10.1007/s11023-018-9482-5. Epub 2018 Nov 26.

This article reports the findings of AI4People, an Atomium-EISMD initiative designed to lay the foundations for a "Good AI Society". We introduce the core opportunities and risks of AI for society; present a synthesis of five ethical principles that...

Advancing understanding and prediction in multiple stressor research through a mechanistic basis for null models.

Global change biology

Schäfer RB, Piggott JJ.
PMID: 29368441
Glob Chang Biol. 2018 May;24(5):1817-1826. doi: 10.1111/gcb.14073. Epub 2018 Feb 21.

Global environmental change is driven by multiple anthropogenic stressors. Conservation and restoration require understanding the individual and joint action of these stressors to evaluate and prioritize management measures. To date, most studies on multiple stressor effects have sought to...

MDM2 antagonists as a novel treatment option for acute myeloid leukemia: perspectives on the therapeutic potential of idasanutlin (RG7388).

OncoTargets and therapy

Khurana A, Shafer DA.
PMID: 31289443
Onco Targets Ther. 2019 Apr 16;12:2903-2910. doi: 10.2147/OTT.S172315. eCollection 2019.

Acute myeloid leukemia (AML) is a clonal heterogenous malignancy of the myeloid cells with a poor prognosis lending itself to novel treatment strategies. TP53 is a critical tumor suppressor and plays an essential role in leukemogenesis. Although TP53 is...

Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis.

EClinicalMedicine

Chimukangara B, Lessells RJ, Rhee SY, Giandhari J, Kharsany ABM, Naidoo K, Lewis L, Cawood C, Khanyile D, Ayalew KA, Diallo K, Samuel R, Hunt G, Vandormael A, Stray-Pedersen B, Gordon M, Makadzange T, Kiepiela P, Ramjee G, Ledwaba J, Kalimashe M, Morris L, Parikh UM, Mellors JW, Shafer RW, Katzenstein D, Moodley P, Gupta RK, Pillay D, Abdool Karim SS, de Oliveira T.
PMID: 31143879
EClinicalMedicine. 2019 Mar 18;9:26-34. doi: 10.1016/j.eclinm.2019.03.006. eCollection 2019 Mar.

BACKGROUND: South Africa has the largest public antiretroviral therapy (ART) programme in the world. We assessed temporal trends in pretreatment HIV-1 drug resistance (PDR) in ART-naïve adults from South Africa.METHODS: We included datasets from studies conducted between 2000 and...

Can Beliefs Be Modified?.

Clinical therapeutics

Shader RI.
PMID: 31133335
Clin Ther. 2019 Jun;41(6):1005-1008. doi: 10.1016/j.clinthera.2019.05.004. Epub 2019 May 24.

No abstract available.

Computerized Cognitive Training by Healthy Older and Younger Adults: Age Comparisons of Overall Efficacy and Selective Effects on Cognition.

Frontiers in neurology

Ng NF, Osman AM, Kerlan KR, Doraiswamy PM, Schafer RJ.
PMID: 33505344
Front Neurol. 2021 Jan 08;11:564317. doi: 10.3389/fneur.2020.564317. eCollection 2020.

Among the non-pharmacological methods under development for maintaining cognitive function across the lifespan is computerized cognitive training (CCT). There has been considerable interest in using CCT to slow or remediate age-related cognitive decline, both normal and pathological. Toward these...

A global agenda for advancing freshwater biodiversity research.

Ecology letters

Maasri A, Jähnig SC, Adamescu MC, Adrian R, Baigun C, Baird DJ, Batista-Morales A, Bonada N, Brown LE, Cai Q, Campos-Silva JV, Clausnitzer V, Contreras-MacBeath T, Cooke SJ, Datry T, Delacámara G, De Meester L, Dijkstra KB, Do VT, Domisch S, Dudgeon D, Erös T, Freitag H, Freyhof J, Friedrich J, Friedrichs-Manthey M, Geist J, Gessner MO, Goethals P, Gollock M, Gordon C, Grossart HP, Gulemvuga G, Gutiérrez-Fonseca PE, Haase P, Hering D, Hahn HJ, Hawkins CP, He F, Heino J, Hermoso V, Hogan Z, Hölker F, Jeschke JM, Jiang M, Johnson RK, Kalinkat G, Karimov BK, Kasangaki A, Kimirei IA, Kohlmann B, Kuemmerlen M, Kuiper JJ, Kupilas B, Langhans SD, Lansdown R, Leese F, Magbanua FS, Matsuzaki SS, Monaghan MT, Mumladze L, Muzon J, Mvogo Ndongo PA, Nejstgaard JC, Nikitina O, Ochs C, Odume ON, Opperman JJ, Patricio H, Pauls SU, Raghavan R, Ramírez A, Rashni B, Ross-Gillespie V, Samways MJ, Schäfer RB, Schmidt-Kloiber A, Seehausen O, Shah DN, Sharma S, Soininen J, Sommerwerk N, Stockwell JD, Suhling F, Tachamo Shah RD, Tharme RE, Thorp JH, Tickner D, Tockner K, Tonkin JD, Valle M, Vitule J, Volk M, Wang D, Wolter C, Worischka S.
PMID: 34854211
Ecol Lett. 2021 Dec 01; doi: 10.1111/ele.13931. Epub 2021 Dec 01.

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind...

Genome assembly, annotation, and comparative analysis of the cattail Typha latifolia.

G3 (Bethesda, Md.)

Widanagama SD, Freeland JR, Xu X, Shafer ABA.
PMID: 34871392
G3 (Bethesda). 2021 Nov 22; doi: 10.1093/g3journal/jkab401. Epub 2021 Nov 22.

Cattails (Typha species) comprise a genus of emergent wetland plants with a global distribution. Typha latifolia and Typha angustifolia are two of the most widespread species, and in areas of sympatry can interbreed to produce the hybrid Typha ×...

SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021.

Microbiology spectrum

Alkhatib M, Svicher V, Salpini R, Ambrosio FA, Bellocchi MC, Carioti L, Piermatteo L, Scutari R, Costa G, Artese A, Alcaro S, Shafer R, Ceccherini-Silberstein F.
PMID: 34787497
Microbiol Spectr. 2021 Dec 22;9(3):e0109621. doi: 10.1128/Spectrum.01096-21. Epub 2021 Nov 17.

Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic caused by it, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been undergoing a genetic diversification leading to the emergence of new variants. Nevertheless, a clear definition of the...

Atypical neural processing during the execution of complex sensorimotor behavior in autism.

Behavioural brain research

Shafer RL, Lewis MH, Newell KM, Bodfish JW.
PMID: 33933522
Behav Brain Res. 2021 Jul 09;409:113337. doi: 10.1016/j.bbr.2021.113337. Epub 2021 Apr 30.

Stereotyped behavior is rhythmic, repetitive movement that is essentially invariant in form. Stereotypy is common in several clinical disorders, such as autism spectrum disorders (ASD), where it is considered maladaptive. However, it also occurs early in typical development (TD)...

Showing 25 to 36 of 226 entries