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Showing 601 to 609 of 609 entries
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Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19.

iScience

Bell LCK, Meydan C, Kim J, Foox J, Butler D, Mason CE, Shapira SD, Noursadeghi M, Pollara G.
PMID: 33319166
iScience. 2021 Jan 22;24(1):101896. doi: 10.1016/j.isci.2020.101896. Epub 2020 Dec 07.

Dysregulated IL-1β and IL-6 responses have been implicated in the pathogenesis of severe Coronavirus Disease 2019 (COVID-19). Innovative approaches for evaluating the biological activity of these cytokines

Case report: A case of Norrie disease due to deletion of the entire coding region of .

American journal of ophthalmology case reports

Zhou Y, Shapiro MJ, Burton BK, Mets MB, Kurup SP.
PMID: 34189345
Am J Ophthalmol Case Rep. 2021 Jun 17;23:101151. doi: 10.1016/j.ajoc.2021.101151. eCollection 2021 Sep.

PURPOSE: Norrie disease is a rare X-linked recessive vitreoretinopathy. Variants of the OBSERVATIONS: A retrospective chart review of the patient's ocular and systemic findings and imaging results was performed. The patient had received genetic testing, including mutational analysis of...

Natural History of Patients With Ischemia and No Obstructive Coronary Artery Disease: The CIAO-ISCHEMIA Study.

Circulation

Reynolds HR, Picard MH, Spertus JA, Peteiro J, Lopez Sendon JL, Senior R, El-Hajjar MC, Celutkiene J, Shapiro MD, Pellikka PA, Kunichoff DF, Anthopolos R, Alfakih K, Abdul-Nour K, Khouri M, Bershtein L, De Belder M, Poh KK, Beltrame JF, Min JK, Fleg JL, Li Y, Maron DJ, Hochman JS.
PMID: 34058845
Circulation. 2021 Sep 28;144(13):1008-1023. doi: 10.1161/CIRCULATIONAHA.120.046791. Epub 2021 Jun 01.

BACKGROUND: Ischemia with no obstructive coronary artery disease (INOCA) is common and has an adverse prognosis. We set out to describe the natural history of symptoms and ischemia in INOCA.METHODS: CIAO-ISCHEMIA (Changes in Ischemia and Angina over One Year...

Genetically encodable materials for non-invasive biological imaging.

Nature materials

Farhadi A, Sigmund F, Westmeyer GG, Shapiro MG.
PMID: 33526879
Nat Mater. 2021 May;20(5):585-592. doi: 10.1038/s41563-020-00883-3. Epub 2021 Feb 01.

Many questions in basic biology and medicine require the ability to visualize the function of specific cells and molecules inside living organisms. In this context, technologies such as ultrasound, optoacoustics and magnetic resonance provide non-invasive imaging access to deep-tissue...

Multimodality Treatment for Advanced Cervical Cancer With Isolated Metastasis to Interventricular Septum of the Heart.

JACC. CardioOncology

Shapira-Daniels A, Katz D, Aviel G, Meirovitz A, Gilon D, Shapira OM.
PMID: 34396262
JACC CardioOncol. 2020 Sep 15;2(3):519-522. doi: 10.1016/j.jaccao.2020.06.008. eCollection 2020 Sep.

No abstract available.

Type 2 diabetes mellitus in heterozygous familial hypercholesterolaemia: the hazardous intersection of cardiometabolic and genetic risk.

European journal of preventive cardiology

German CA, Shapiro MD.
PMID: 33961017
Eur J Prev Cardiol. 2022 Jan 11;28(16):1817-1818. doi: 10.1093/eurjpc/zwab057.

No abstract available.

Severe aortic stenosis echocardiographic thresholds revisited.

Echocardiography (Mount Kisco, N.Y.)

Schwartzenberg S, Vatury M, Wiessman M, Shechter A, Morelli O, Ofek H, Kazum S, Kornowski R, Sagie A, Shapira Y.
PMID: 34854128
Echocardiography. 2021 Dec;38(12):2016-2024. doi: 10.1111/echo.15241. Epub 2021 Dec 01.

BACKGROUND: In view of inconsistencies in threshold values of severe aortic stenosis (AS) hemodynamic indices, it is unclear what is the relative contribution of each variable in a binary classification of AS based on aortic valve replacement (AVR) indication....

Identification of Immune complement function as a determinant of adverse SARS-CoV-2 infection outcome.

medRxiv : the preprint server for health sciences

Ramlall V, Thangaraj PM, Meydan C, Foox J, Butler D, May B, De Freitas JK, Glicksberg BS, Mason CE, Tatonetti NP, Shapira SD.
PMID: 32511494
medRxiv. 2020 Jun 06; doi: 10.1101/2020.05.05.20092452.

Understanding the pathophysiology of SARS-CoV-2 infection is critical for therapeutics and public health intervention strategies. Viral-host interactions can guide discovery of regulators of disease outcomes, and protein structure function analysis points to several immune pathways, including complement and coagulation,...

Willingness to Travel for Cellular Therapy: The Influence of Follow-Up Care Location, Oncologist Continuity, and Race.

JCO oncology practice

Frosch ZAK, Namoglu EC, Mitra N, Landsburg DJ, Nasta SD, Bekelman JE, Iyengar R, Guerra CE, Schapira MM.
PMID: 34524837
JCO Oncol Pract. 2022 Jan;18(1):e193-e203. doi: 10.1200/OP.21.00312. Epub 2021 Sep 15.

PURPOSE: Patients weigh competing priorities when deciding whether to travel to a cellular therapy center for treatment. We conducted a choice-based conjoint analysis to determine the relative value they place on clinical factors, oncologist continuity, and travel time under...

Showing 601 to 609 of 609 entries