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Aging is associated with increased brain iron through cortex-derived hepcidin expression.

eLife

Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H.
PMID: 35014607
Elife. 2022 Jan 11;11. doi: 10.7554/eLife.73456.

Iron is an essential molecule for biological processes, but its accumulation can lead to oxidative stress and cellular death. Due to its oxidative effects, iron accumulation is implicated in the process of aging and neurodegenerative diseases. However, the mechanism...

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Sato T, Shapiro JS, Chang HC, et al. Aging is associated with increased brain iron through cortex-derived hepcidin expression. Elife. 2022;11doi: 10.7554/eLife.73456.
Sato, T., Shapiro, J. S., Chang, H. C., Miller, R. A., & Ardehali, H. (2022). Aging is associated with increased brain iron through cortex-derived hepcidin expression. eLife, 11. https://doi.org/10.7554/eLife.73456
Sato, Tatsuya, et al. "Aging is associated with increased brain iron through cortex-derived hepcidin expression." eLife vol. 11 (2022). doi: https://doi.org/10.7554/eLife.73456
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H. Aging is associated with increased brain iron through cortex-derived hepcidin expression. Elife. 2022 Jan 11;11. doi: 10.7554/eLife.73456. PMID: 35014607; PMCID: PMC8752087.
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Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition.

Placenta

Mao Q, Chu S, Shapiro S, Young L, Russo M, De Paepe ME.
PMID: 34929459
Placenta. 2021 Dec 02;117:187-193. doi: 10.1016/j.placenta.2021.12.002. Epub 2021 Dec 02.

INTRODUCTION: Recent evidence supports the - rare - occurrence of vertical transplacental SARS-CoV-2 transmission. We previously determined that placental expression of angiotensin-converting enzyme 2 (ACE2), the SARS-CoV-2 receptor, and associated viral cell entry regulators is upregulated by hypoxia. In...

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Mao Q, Chu S, Shapiro S, et al. Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition. Placenta. 2021;117:187-193doi: 10.1016/j.placenta.2021.12.002.
Mao, Q., Chu, S., Shapiro, S., Young, L., Russo, M., & De Paepe, M. E. (2021). Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition. Placenta, 117187-193. https://doi.org/10.1016/j.placenta.2021.12.002
Mao, Quanfu, et al. "Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition." Placenta vol. 117 (2021): 187-193. doi: https://doi.org/10.1016/j.placenta.2021.12.002
Mao Q, Chu S, Shapiro S, Young L, Russo M, De Paepe ME. Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition. Placenta. 2021 Dec 02;117:187-193. doi: 10.1016/j.placenta.2021.12.002. Epub 2021 Dec 02. PMID: 34929459; PMCID: PMC8638245.
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A New Insight on Exophytic Serous Borderline Adnexal Tumors: Specific Sonographic Features.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

Haddad L, Kugelman N, Shapiro I, Bakry H, Weizman B, Korobochka R, Sagie S, Said-Idris S, Bejar J, Leibovitz Z.
PMID: 34562042
J Ultrasound Med. 2021 Sep 25; doi: 10.1002/jum.15838. Epub 2021 Sep 25.

OBJECTIVES: To characterize and compare the sonographic features of exophytic serous borderline ovarian tumors (ESBOT) with those of high-grade serous carcinoma of the ovary (HGSC).METHODS: Seven patients with histological diagnosis of ESBOT diagnosed between 2011 and 2019 and 10...

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Haddad L, Kugelman N, Shapiro I, et al. A New Insight on Exophytic Serous Borderline Adnexal Tumors: Specific Sonographic Features. J Ultrasound Med. 2021;doi: 10.1002/jum.15838.
Haddad, L., Kugelman, N., Shapiro, I., Bakry, H., Weizman, B., Korobochka, R., Sagie, S., Said-Idris, S., Bejar, J., & Leibovitz, Z. (2021). A New Insight on Exophytic Serous Borderline Adnexal Tumors: Specific Sonographic Features. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, . https://doi.org/10.1002/jum.15838
Haddad, Leila, et al. "A New Insight on Exophytic Serous Borderline Adnexal Tumors: Specific Sonographic Features." Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine vol. (2021). doi: https://doi.org/10.1002/jum.15838
Haddad L, Kugelman N, Shapiro I, Bakry H, Weizman B, Korobochka R, Sagie S, Said-Idris S, Bejar J, Leibovitz Z. A New Insight on Exophytic Serous Borderline Adnexal Tumors: Specific Sonographic Features. J Ultrasound Med. 2021 Sep 25; doi: 10.1002/jum.15838. Epub 2021 Sep 25. PMID: 34562042.
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Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury.

Neural regeneration research

Herr SA, Shi L, Gianaris T, Jiao Y, Sun S, Race N, Shapiro S, Shi R.
PMID: 34916435
Neural Regen Res. 2022 Jul;17(7):1505-1511. doi: 10.4103/1673-5374.330613.

Lipid peroxidation-derived aldehydes, such as acrolein, the most reactive aldehyde, have emerged as key culprits in sustaining post-spinal cord injury (SCI) secondary pathologies leading to functional loss. Strong evidence suggests that mitochondrial aldehyde dehydrogenase-2 (ALDH2), a key oxidoreductase and...

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Herr SA, Shi L, Gianaris T, et al. Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury. Neural Regen Res. 2022;17(7):1505-1511doi: 10.4103/1673-5374.330613.
Herr, S. A., Shi, L., Gianaris, T., Jiao, Y., Sun, S., Race, N., Shapiro, S., & Shi, R. (2022). Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury. Neural regeneration research, 17(7), 1505-1511. https://doi.org/10.4103/1673-5374.330613
Herr, Seth A, et al. "Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury." Neural regeneration research vol. 17,7 (2022): 1505-1511. doi: https://doi.org/10.4103/1673-5374.330613
Herr SA, Shi L, Gianaris T, Jiao Y, Sun S, Race N, Shapiro S, Shi R. Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury. Neural Regen Res. 2022 Jul;17(7):1505-1511. doi: 10.4103/1673-5374.330613. PMID: 34916435.
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Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study.

British journal of haematology

Arachchillage DJ, Rajakaruna I, Odho Z, Crossette-Thambiah C, Nicolson PLR, Roberts LN, Allan C, Lewis S, Riat R, Mounter P, Lynch C, Langridge A, Oakes R, Aung N, Drebes A, Dutt T, Raheja P, Delaney A, Essex S, Lowe G, Sutton D, Lentaigne C, Sayar Z, Kilner M, Everington T, Shapiro S, Alikhan R, Szydlo R, Makris M, Laffan M.
PMID: 34500500
Br J Haematol. 2022 Jan;196(1):79-94. doi: 10.1111/bjh.17787. Epub 2021 Sep 09.

Coagulation dysfunction and thrombosis are major complications in patients with coronavirus disease 2019 (COVID-19). Patients on oral anticoagulants (OAC) prior to diagnosis of COVID-19 may therefore have better outcomes. In this multicentre observational study of 5 883 patients (≥18...

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Arachchillage DJ, Rajakaruna I, Odho Z, et al. Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study. Br J Haematol. 2021;196(1):79-94doi: 10.1111/bjh.17787.
Arachchillage, D. J., Rajakaruna, I., Odho, Z., Crossette-Thambiah, C., Nicolson, P. L. R., Roberts, L. N., Allan, C., Lewis, S., Riat, R., Mounter, P., Lynch, C., Langridge, A., Oakes, R., Aung, N., Drebes, A., Dutt, T., Raheja, P., Delaney, A., Essex, S., Lowe, G., Sutton, D., Lentaigne, C., Sayar, Z., Kilner, M., Everington, T., Shapiro, S., Alikhan, R., Szydlo, R., Makris, M., & Laffan, M. (2022). Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study. British journal of haematology, 196(1), 79-94. https://doi.org/10.1111/bjh.17787
Arachchillage, Deepa J, et al. "Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study." British journal of haematology vol. 196,1 (2022): 79-94. doi: https://doi.org/10.1111/bjh.17787
Arachchillage DJ, Rajakaruna I, Odho Z, Crossette-Thambiah C, Nicolson PLR, Roberts LN, Allan C, Lewis S, Riat R, Mounter P, Lynch C, Langridge A, Oakes R, Aung N, Drebes A, Dutt T, Raheja P, Delaney A, Essex S, Lowe G, Sutton D, Lentaigne C, Sayar Z, Kilner M, Everington T, Shapiro S, Alikhan R, Szydlo R, Makris M, Laffan M. Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study. Br J Haematol. 2022 Jan;196(1):79-94. doi: 10.1111/bjh.17787. Epub 2021 Sep 09. PMID: 34500500.
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Rational design of a new antibiotic class for drug-resistant infections.

Nature

Durand-Reville TF, Miller AA, O'Donnell JP, Wu X, Sylvester MA, Guler S, Iyer R, Shapiro AB, Carter NM, Velez-Vega C, Moussa SH, McLeod SM, Chen A, Tanudra AM, Zhang J, Comita-Prevoir J, Romero JA, Huynh H, Ferguson AD, Horanyi PS, Mayclin SJ, Heine HS, Drusano GL, Cummings JE, Slayden RA, Tommasi RA.
PMID: 34526714
Nature. 2021 Sep;597(7878):698-702. doi: 10.1038/s41586-021-03899-0. Epub 2021 Sep 15.

The development of new antibiotics to treat infections caused by drug-resistant Gram-negative pathogens is of paramount importance as antibiotic resistance continues to increase worldwide

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Durand-Reville TF, Miller AA, O'Donnell JP, et al. Rational design of a new antibiotic class for drug-resistant infections. Nature. 2021;597(7878):698-702doi: 10.1038/s41586-021-03899-0.
Durand-Reville, T. F., Miller, A. A., O'Donnell, J. P., Wu, X., Sylvester, M. A., Guler, S., Iyer, R., Shapiro, A. B., Carter, N. M., Velez-Vega, C., Moussa, S. H., McLeod, S. M., Chen, A., Tanudra, A. M., Zhang, J., Comita-Prevoir, J., Romero, J. A., Huynh, H., Ferguson, A. D., Horanyi, P. S., Mayclin, S. J., Heine, H. S., Drusano, G. L., Cummings, J. E., Slayden, R. A., & Tommasi, R. A. (2021). Rational design of a new antibiotic class for drug-resistant infections. Nature, 597(7878), 698-702. https://doi.org/10.1038/s41586-021-03899-0
Durand-Reville, Thomas F, et al. "Rational design of a new antibiotic class for drug-resistant infections." Nature vol. 597,7878 (2021): 698-702. doi: https://doi.org/10.1038/s41586-021-03899-0
Durand-Reville TF, Miller AA, O'Donnell JP, Wu X, Sylvester MA, Guler S, Iyer R, Shapiro AB, Carter NM, Velez-Vega C, Moussa SH, McLeod SM, Chen A, Tanudra AM, Zhang J, Comita-Prevoir J, Romero JA, Huynh H, Ferguson AD, Horanyi PS, Mayclin SJ, Heine HS, Drusano GL, Cummings JE, Slayden RA, Tommasi RA. Rational design of a new antibiotic class for drug-resistant infections. Nature. 2021 Sep;597(7878):698-702. doi: 10.1038/s41586-021-03899-0. Epub 2021 Sep 15. PMID: 34526714.
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Firearm Acoustic Detection in Hartford, Connecticut: Outcomes of a Trauma Center - Law Enforcement Collaboration.

Cureus

Gontarz BR, Siddiqui UT, Campbell B, Gates J, O'Hare JM, Green C, McQuay J, Shapiro DS.
PMID: 34804655
Cureus. 2021 Oct 14;13(10):e18789. doi: 10.7759/cureus.18789. eCollection 2021 Oct.

Introduction Firearm homicide is a leading cause of violence-related death in the United States.Unfortunately, more than 80% of illegal firearm discharges are never reported to police by traditional means.ShotSpotter

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Gontarz BR, Siddiqui UT, Campbell B, et al. Firearm Acoustic Detection in Hartford, Connecticut: Outcomes of a Trauma Center - Law Enforcement Collaboration. Cureus. 2021;13(10):e18789doi: 10.7759/cureus.18789.
Gontarz, B. R., Siddiqui, U. T., Campbell, B., Gates, J., O'Hare, J. M., Green, C., McQuay, J., & Shapiro, D. S. (2021). Firearm Acoustic Detection in Hartford, Connecticut: Outcomes of a Trauma Center - Law Enforcement Collaboration. Cureus, 13(10), e18789. https://doi.org/10.7759/cureus.18789
Gontarz, Brendan R, et al. "Firearm Acoustic Detection in Hartford, Connecticut: Outcomes of a Trauma Center - Law Enforcement Collaboration." Cureus vol. 13,10 (2021): e18789. doi: https://doi.org/10.7759/cureus.18789
Gontarz BR, Siddiqui UT, Campbell B, Gates J, O'Hare JM, Green C, McQuay J, Shapiro DS. Firearm Acoustic Detection in Hartford, Connecticut: Outcomes of a Trauma Center - Law Enforcement Collaboration. Cureus. 2021 Oct 14;13(10):e18789. doi: 10.7759/cureus.18789. eCollection 2021 Oct. PMID: 34804655; PMCID: PMC8592377.
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Validation of the SCAT5 and Child SCAT5 Word-List Memory Task.

Journal of neurotrauma

Shapiro JS, Hearps S, Rausa VC, Anderson V, Anderson N, Pugh R, Chau T, Clarke C, Davis GA, Fabiano F, Fan F, Parkin GM, Takagi M, Babl FE.
PMID: 33765839
J Neurotrauma. 2021 May 10; doi: 10.1089/neu.2020.7414. Epub 2021 May 10.

The Sports Concussion Assessment Tool-5th Edition (SCAT5) and the child version (Child SCAT5) are the current editions of the SCAT and have updated the memory testing component from previous editions. This study aimed to validate this new memory component...

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Shapiro JS, Hearps S, Rausa VC, et al. Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. J Neurotrauma. 2021;doi: 10.1089/neu.2020.7414.
Shapiro, J. S., Hearps, S., Rausa, V. C., Anderson, V., Anderson, N., Pugh, R., Chau, T., Clarke, C., Davis, G. A., Fabiano, F., Fan, F., Parkin, G. M., Takagi, M., & Babl, F. E. (2021). Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. Journal of neurotrauma, . https://doi.org/10.1089/neu.2020.7414
Shapiro, Jesse S, et al. "Validation of the SCAT5 and Child SCAT5 Word-List Memory Task." Journal of neurotrauma vol. (2021). doi: https://doi.org/10.1089/neu.2020.7414
Shapiro JS, Hearps S, Rausa VC, Anderson V, Anderson N, Pugh R, Chau T, Clarke C, Davis GA, Fabiano F, Fan F, Parkin GM, Takagi M, Babl FE. Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. J Neurotrauma. 2021 May 10; doi: 10.1089/neu.2020.7414. Epub 2021 May 10. PMID: 33765839.
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The Impact of Retinal Configuration on the Protein-Chromophore Interactions in Bistable Jumping Spider Rhodopsin-1.

Molecules (Basel, Switzerland)

Church JR, Olsen JMH, Schapiro I.
PMID: 35011302
Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010071.

Bistable rhodopsins have two stable forms that can be interconverted by light. Due to their ability to act as photoswitches, these proteins are considered as ideal candidates for applications such as optogenetics. In this work, we analyze a recently...

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Church JR, Olsen JMH, Schapiro I. The Impact of Retinal Configuration on the Protein-Chromophore Interactions in Bistable Jumping Spider Rhodopsin-1. Molecules. 2021;27(1)doi: 10.3390/molecules27010071.
Church, J. R., Olsen, J. M. H., & Schapiro, I. (2021). The Impact of Retinal Configuration on the Protein-Chromophore Interactions in Bistable Jumping Spider Rhodopsin-1. Molecules (Basel, Switzerland), 27(1), . https://doi.org/10.3390/molecules27010071
Church, Jonathan R, et al. "The Impact of Retinal Configuration on the Protein-Chromophore Interactions in Bistable Jumping Spider Rhodopsin-1." Molecules (Basel, Switzerland) vol. 27,1 (2021). doi: https://doi.org/10.3390/molecules27010071
Church JR, Olsen JMH, Schapiro I. The Impact of Retinal Configuration on the Protein-Chromophore Interactions in Bistable Jumping Spider Rhodopsin-1. Molecules. 2021 Dec 23;27(1). doi: 10.3390/molecules27010071. PMID: 35011302; PMCID: PMC8746357.
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Showing 409 to 417 of 417 entries