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Showing 25 to 36 of 333 entries
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Influence of genomic ancestry and self-reported color-race in CKD in a nationwide admixed sample of Brazilian patients with type 1 diabetes.

Diabetes, metabolic syndrome and obesity : targets and therapy

Pizarro MH, Santos DC, Melo LGN, Barros BSV, Muniz LH, Porto LC, Silva DA, Gomes MB.
PMID: 31571958
Diabetes Metab Syndr Obes. 2019 Sep 12;12:1831-1840. doi: 10.2147/DMSO.S210585. eCollection 2019.

AIMS: Patients with diabetes that are African-Americans or Asians have a higher chance of developing diabetic nephropathy than Caucasian. Our objective was to evaluate the association between self-reported color-race, genomic ancestry, and the presence of chronic kidney disease (CKD),...

Human Mesenchymal Stem Cell Therapy Reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice.

Frontiers in pharmacology

Alencar AKN, Pimentel-Coelho PM, Montes GC, da Silva MMC, Mendes LVP, Montagnoli TL, Silva AMS, Vasques JF, Rosado-de-Castro PH, Gutfilen B, Cunha VDMN, Fraga AGM, Silva PMRE, Martins MA, Ferreira TPT, Mendes-Otero R, Trachez MM, Sudo RT, Zapata-Sudo G.
PMID: 30574088
Front Pharmacol. 2018 Dec 06;9:1395. doi: 10.3389/fphar.2018.01395. eCollection 2018.

No abstract available.

Bioactive compounds and hepatoprotective effect of .

Natural product research

Santos RS, Chaves-Filho AB, Silva LAS, Garcia CAB, Silva ARST, Dolabella SS, da Costa SSL, Miyamoto S, Matos HR.
PMID: 33749461
Nat Prod Res. 2021 Mar 22;1-5. doi: 10.1080/14786419.2021.1902324. Epub 2021 Mar 22.

No abstract available.

Ethical health security in the age of antimicrobial resistance.

BMJ global health

Pahlman K, Fehross A, Fox GJ, Silva DS.
PMID: 34996766
BMJ Glob Health. 2022 Jan;7(1). doi: 10.1136/bmjgh-2021-007407.

OBJECTIVE: Owing to its potential human, social and economic costs, antimicrobial resistance (AMR) is frequently referred to as a threat to health security. Simultaneously, health security and the preservation of antimicrobials are often described as a global public good....

Interaction of human complement factor H variants Tyr⁴⁰² and His⁴⁰² with Leptospira spp.

Frontiers in immunology

Silva AS, Valencia MM, Cianciarullo AM, Vasconcellos SA, Barbosa AS, Isaac L.
PMID: 22566834
Front Immunol. 2011 Oct 05;2:44. doi: 10.3389/fimmu.2011.00044. eCollection 2011.

Leptospirosis is a zoonosis caused by pathogenic bacteria from the genus Leptospira. The disease represents a serious public health problem in underdeveloped tropical countries. Leptospires infect hosts through small abrasions in the skin or mucous membranes and they rapidly...

Practical applicability of genetics for the prevention and treatment of hypertension.

Journal of clinical hypertension (Greenwich, Conn.)

Silva AS.
PMID: 34962054
J Clin Hypertens (Greenwich). 2021 Dec 28; doi: 10.1111/jch.14400. Epub 2021 Dec 28.

Zou and colleagues are publishing in this issue of The Journal of Clinical Hypertension, result of one of their studies in which they found that human corin genetic polymorphisms is involved in blood pressure control, more specifically in salt...

Antioxidant and Antigenotoxic Actions of Gum Arabic on the Intestinal Mucosa, Liver and Bone Marrow of .

Nutrition and cancer

Avelino ALN, Silva NVRE, Oliveira GB, Silva AAS, Cavalcanti BC, Jamacaru FVF, Dornelas CA.
PMID: 34085880
Nutr Cancer. 2021 Jun 04;1-9. doi: 10.1080/01635581.2021.1931699. Epub 2021 Jun 04.

Colorectal carcinogenesis is characterized by oxidative stress and the formation of aberrant crypts in its initial stages. Gum arabic (GA) is a natural product with antioxidant properties, and, therefore, supposed antitumor action. The aim of this study was to...

Yeast Double Transporter Gene Deletion Library for Identification of Xenobiotic Carriers in Low or High Throughput.

mBio

Almeida LD, Silva ASF, Mota DC, Vasconcelos AA, Camargo AP, Pires GS, Furlan M, Freire HMRDC, Klippel AH, Silva SF, Zanelli CF, Carazzolle MF, Oliver SG, Bilsland E.
PMID: 34903049
mBio. 2021 Dec 14;e0322121. doi: 10.1128/mbio.03221-21. Epub 2021 Dec 14.

The routes of uptake and efflux should be considered when developing new drugs so that they can effectively address their intracellular targets. As a general rule, drugs appear to enter cells via protein carriers that normally carry nutrients or...

Inulinase from .

Food science and biotechnology

de Araujo Ribeiro GC, Fernandes P, Silva DAA, Brandão HN, de Assis SA.
PMID: 34395027
Food Sci Biotechnol. 2021 Jun 16;30(7):959-969. doi: 10.1007/s10068-021-00931-x. eCollection 2021 Jul.

The crude extract containing inulinase from

Dissecting EPPIN protease inhibitor domains in sperm motility and fertilizing ability: repercussions for male contraceptive development.

Molecular human reproduction

Silva AAS, Raimundo TRF, Mariani NAP, Kushima H, Avellar MCW, Buffone MG, Paula-Lopes FF, Moura MT, Silva EJR.
PMID: 34792600
Mol Hum Reprod. 2021 Nov 27;27(12). doi: 10.1093/molehr/gaab066.

EPPIN (epididymal protease inhibitor) is a mammalian conserved sperm-binding protein displaying an N-terminal WFDC (whey-acidic protein four-disulfide core) and a C-terminal Kunitz protease inhibitor domains. EPPIN plays a key role in regulating sperm motility after ejaculation via interaction with...

Comparison of Mechanical Resistance to Maximal Torsion Stress in Original and Nonoriginal or Compatible Prosthetic Implant Screws: An In Vitro Study.

International journal of dentistry

Silva AS, Mendes JM, Araújo T, Aroso C, Barreiros P.
PMID: 34899914
Int J Dent. 2021 Dec 02;2021:5133556. doi: 10.1155/2021/5133556. eCollection 2021.

Micromovements of the implant-abutment connection influence peri-implant bone preservation. The maximal torque after a cycle of implant prosthetic screw tightening using original components of different manufacturers and replicas produced by other companies is evaluated and quantified in this study....

Effect of different food and sugar sources on the larval biology and adult longevity of Anopheles darlingi (Diptera: Culicidae).

Tropical biomedicine

Zanin CRF, Trindade FTT, Silva AAE.
PMID: 33597419
Trop Biomed. 2019 Jun 01;36(2):569-577.

Anopheles darlingi is the main vector of the disease in the Amazon, and several studies on its ecology and behavior have been conducted. Although the basic nutritional requirements of insects are well known, quantitative needs with respect to food...

Showing 25 to 36 of 333 entries