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Showing 901 to 910 of 910 entries
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Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview.

Current drug targets

Estevinho MM, Fernandes C, Silva JC, Gomes AC, Afecto E, Correia J, Carvalho J.
PMID: 33845738
Curr Drug Targets. 2021 Apr 12; doi: 10.2174/1389450122666210412125018. Epub 2021 Apr 12.

BACKGROUND: Molecular therapy with sorafenib remains the mainstay for advanced-stage hepatocellular carcinoma. Notwithstanding, treatment efficacy is low, with few patients obtaining long-lasting benefits due to the high chemoresistance rate.OBJECTIVE: To perform, for the first time, an overview of the...

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Estevinho MM, Fernandes C, Silva JC, et al. Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview. Curr Drug Targets. 2021;doi: 10.2174/1389450122666210412125018.
Estevinho, M. M., Fernandes, C., Silva, J. C., Gomes, A. C., Afecto, E., Correia, J., & Carvalho, J. (2021). Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview. Current drug targets, . https://doi.org/10.2174/1389450122666210412125018
Estevinho, Maria Manuela, et al. "Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview." Current drug targets vol. (2021). doi: https://doi.org/10.2174/1389450122666210412125018
Estevinho MM, Fernandes C, Silva JC, Gomes AC, Afecto E, Correia J, Carvalho J. Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview. Curr Drug Targets. 2021 Apr 12; doi: 10.2174/1389450122666210412125018. Epub 2021 Apr 12. PMID: 33845738.
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(-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B.

Life sciences

Magalhães EP, Silva BP, Aires NL, Ribeiro LR, Ali A, Cavalcanti MM, Nunes JVS, Sampaio TL, de Menezes RRPPB, Martins AMC.
PMID: 34974077
Life Sci. 2021 Dec 30;291:120271. doi: 10.1016/j.lfs.2021.120271. Epub 2021 Dec 30.

INTRODUCTION: Amphotericin B (AmB), used for systemic fungal infections, has a limited clinical application because of its high nephrotoxicity. Natural antioxidant and anti-inflammatory substances have been widely studied for protection against drug-induced nephrotoxicity. α-Bisabolol (BIS) has demonstrated a nephroprotective...

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Magalhães EP, Silva BP, Aires NL, et al. (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. Life Sci. 2021;291:120271doi: 10.1016/j.lfs.2021.120271.
Magalhães, E. P., Silva, B. P., Aires, N. L., Ribeiro, L. R., Ali, A., Cavalcanti, M. M., Nunes, J. V. S., Sampaio, T. L., de Menezes, R. R. P. P. B., & Martins, A. M. C. (2021). (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. Life sciences, 291120271. https://doi.org/10.1016/j.lfs.2021.120271
Magalhães, Emanuel Paula, et al. "(-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B." Life sciences vol. 291 (2021): 120271. doi: https://doi.org/10.1016/j.lfs.2021.120271
Magalhães EP, Silva BP, Aires NL, Ribeiro LR, Ali A, Cavalcanti MM, Nunes JVS, Sampaio TL, de Menezes RRPPB, Martins AMC. (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. Life Sci. 2021 Dec 30;291:120271. doi: 10.1016/j.lfs.2021.120271. Epub 2021 Dec 30. PMID: 34974077.
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Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine.

mBio

Dos Reis TF, Horta MAC, Colabardini AC, Fernandes CM, Silva LP, Bastos RW, Fonseca MVL, Wang F, Martins C, Rodrigues ML, Silva Pereira C, Del Poeta M, Wong KH, Goldman GH.
PMID: 34372704
mBio. 2021 Aug 31;12(4):e0145821. doi: 10.1128/mBio.01458-21. Epub 2021 Aug 10.

Aspergillus fumigatus is an important fungal pathogen and the main etiological agent of aspergillosis, a disease characterized by a noninvasive process that can evolve to a more severe clinical manifestation, called invasive pulmonary aspergillosis (IPA), in immunocompromised patients. The...

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Dos Reis TF, Horta MAC, Colabardini AC, et al. Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine. mBio. 2021;12(4):e0145821doi: 10.1128/mBio.01458-21.
Dos Reis, T. F., Horta, M. A. C., Colabardini, A. C., Fernandes, C. M., Silva, L. P., Bastos, R. W., Fonseca, M. V. L., Wang, F., Martins, C., Rodrigues, M. L., Silva Pereira, C., Del Poeta, M., Wong, K. H., & Goldman, G. H. (2021). Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine. mBio, 12(4), e0145821. https://doi.org/10.1128/mBio.01458-21
Dos Reis, Thaila Fernanda, et al. "Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine." mBio vol. 12,4 (2021): e0145821. doi: https://doi.org/10.1128/mBio.01458-21
Dos Reis TF, Horta MAC, Colabardini AC, Fernandes CM, Silva LP, Bastos RW, Fonseca MVL, Wang F, Martins C, Rodrigues ML, Silva Pereira C, Del Poeta M, Wong KH, Goldman GH. Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine. mBio. 2021 Aug 31;12(4):e0145821. doi: 10.1128/mBio.01458-21. Epub 2021 Aug 10. PMID: 34372704; PMCID: PMC8406317.
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IoT Registration and Authentication in Smart City Applications with Blockchain.

Sensors (Basel, Switzerland)

Ferreira CMS, Garrocho CTB, Oliveira RAR, Silva JS, Cavalcanti CFMDC.
PMID: 33668415
Sensors (Basel). 2021 Feb 13;21(4). doi: 10.3390/s21041323.

The advent of 5G will bring a massive adoption of IoT devices across our society. IoT Applications (IoT Apps) will be the primary data collection base. This scenario leads to unprecedented scalability and security challenges, with one of the...

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Ferreira CMS, Garrocho CTB, Oliveira RAR, et al. IoT Registration and Authentication in Smart City Applications with Blockchain. Sensors (Basel). 2021;21(4)doi: 10.3390/s21041323.
Ferreira, C. M. S., Garrocho, C. T. B., Oliveira, R. A. R., Silva, J. S., & Cavalcanti, C. F. M. D. C. (2021). IoT Registration and Authentication in Smart City Applications with Blockchain. Sensors (Basel, Switzerland), 21(4), . https://doi.org/10.3390/s21041323
Ferreira, Célio Márcio Soares, et al. "IoT Registration and Authentication in Smart City Applications with Blockchain." Sensors (Basel, Switzerland) vol. 21,4 (2021). doi: https://doi.org/10.3390/s21041323
Ferreira CMS, Garrocho CTB, Oliveira RAR, Silva JS, Cavalcanti CFMDC. IoT Registration and Authentication in Smart City Applications with Blockchain. Sensors (Basel). 2021 Feb 13;21(4). doi: 10.3390/s21041323. PMID: 33668415; PMCID: PMC7918502.
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Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice.

Behavioural brain research

P B Gomes M, de Lima EV, G Q Barros-Aragão F, Passos YM, Lemos FS, Zamberlan DC, Ribeiro G, Macedo B, C Ferreira N, Silva JL, Figueiredo CP, Clarke JR, Cordeiro Y.
PMID: 34822947
Behav Brain Res. 2022 Feb 15;419:113680. doi: 10.1016/j.bbr.2021.113680. Epub 2021 Nov 22.

Conversion of the cellular prion protein (PrP

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P B Gomes M, de Lima EV, G Q Barros-Aragão F, et al. Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice. Behav Brain Res. 2021;419:113680doi: 10.1016/j.bbr.2021.113680.
P B Gomes, M., de Lima, E. V., G Q Barros-Aragão, F., Passos, Y. M., Lemos, F. S., Zamberlan, D. C., Ribeiro, G., Macedo, B., C Ferreira, N., Silva, J. L., Figueiredo, C. P., Clarke, J. R., & Cordeiro, Y. (2022). Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice. Behavioural brain research, 419113680. https://doi.org/10.1016/j.bbr.2021.113680
P B Gomes, Mariana, et al. "Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice." Behavioural brain research vol. 419 (2022): 113680. doi: https://doi.org/10.1016/j.bbr.2021.113680
P B Gomes M, de Lima EV, G Q Barros-Aragão F, Passos YM, Lemos FS, Zamberlan DC, Ribeiro G, Macedo B, C Ferreira N, Silva JL, Figueiredo CP, Clarke JR, Cordeiro Y. Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice. Behav Brain Res. 2022 Feb 15;419:113680. doi: 10.1016/j.bbr.2021.113680. Epub 2021 Nov 22. PMID: 34822947.
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Bioresilience to Mercury Chloride of the Brine Shrimp Artemia Salina after Treatment with Homeopathic Mercurius Corrosivus.

Homeopathy : the journal of the Faculty of Homeopathy

Pinto AAG, Nagai MYO, Coimbra EN, Mohammad SN, Silva JS, Von Ancken A, Pinto SAG, Aguiar MS, Dutra-Correa M, Hortellani MA, Miranda A, Sarkis JES, Suffredini IB, Peres GB, Bernardi MM, Cartwright SJ, Bonamin LV.
PMID: 34474498
Homeopathy. 2021 Nov;110(4):244-255. doi: 10.1055/s-0041-1729562. Epub 2021 Sep 02.

INTRODUCTION:  Finding solutions to mitigate the impact of pollution on living systems is a matter of great interest. Homeopathic preparations of toxic substances have been described in the literature as attenuation factors for intoxication. Herein, an experimental study using...

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Pinto AAG, Nagai MYO, Coimbra EN, et al. Bioresilience to Mercury Chloride of the Brine Shrimp Artemia Salina after Treatment with Homeopathic Mercurius Corrosivus. Homeopathy. 2021;110(4):244-255doi: 10.1055/s-0041-1729562.
Pinto, A. A. G., Nagai, M. Y. O., Coimbra, E. N., Mohammad, S. N., Silva, J. S., Von Ancken, A., Pinto, S. A. G., Aguiar, M. S., Dutra-Correa, M., Hortellani, M. A., Miranda, A., Sarkis, J. E. S., Suffredini, I. B., Peres, G. B., Bernardi, M. M., Cartwright, S. J., & Bonamin, L. V. (2021). Bioresilience to Mercury Chloride of the Brine Shrimp Artemia Salina after Treatment with Homeopathic Mercurius Corrosivus. Homeopathy : the journal of the Faculty of Homeopathy, 110(4), 244-255. https://doi.org/10.1055/s-0041-1729562
Pinto, Andreia Adelaide G, et al. "Bioresilience to Mercury Chloride of the Brine Shrimp Artemia Salina after Treatment with Homeopathic Mercurius Corrosivus." Homeopathy : the journal of the Faculty of Homeopathy vol. 110,4 (2021): 244-255. doi: https://doi.org/10.1055/s-0041-1729562
Pinto AAG, Nagai MYO, Coimbra EN, Mohammad SN, Silva JS, Von Ancken A, Pinto SAG, Aguiar MS, Dutra-Correa M, Hortellani MA, Miranda A, Sarkis JES, Suffredini IB, Peres GB, Bernardi MM, Cartwright SJ, Bonamin LV. Bioresilience to Mercury Chloride of the Brine Shrimp Artemia Salina after Treatment with Homeopathic Mercurius Corrosivus. Homeopathy. 2021 Nov;110(4):244-255. doi: 10.1055/s-0041-1729562. Epub 2021 Sep 02. PMID: 34474498.
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Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract.

Pharmacology research & perspectives

Nader-Macías MEF, De Gregorio PR, Silva JA.
PMID: 34609059
Pharmacol Res Perspect. 2021 Oct;9(5):e00787. doi: 10.1002/prp2.787.

Lactobacilli are the predominant microorganisms of the healthy human vagina. A novel alternative for the prevention and treatment of female urogenital tract infections (UGTI) is the inclusion of these microorganisms as active pharmaceutical ingredients in probiotic formulas, and more...

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Nader-Macías MEF, De Gregorio PR, Silva JA. Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract. Pharmacol Res Perspect. 2021;9(5):e00787doi: 10.1002/prp2.787.
Nader-Macías, M. E. F., De Gregorio, P. R., & Silva, J. A. (2021). Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract. Pharmacology research & perspectives, 9(5), e00787. https://doi.org/10.1002/prp2.787
Nader-Macías, María Elena Fátima, et al. "Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract." Pharmacology research & perspectives vol. 9,5 (2021): e00787. doi: https://doi.org/10.1002/prp2.787
Nader-Macías MEF, De Gregorio PR, Silva JA. Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract. Pharmacol Res Perspect. 2021 Oct;9(5):e00787. doi: 10.1002/prp2.787. PMID: 34609059; PMCID: PMC8491456.
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Transcriptome dataset of .

Data in brief

Ueti MW, Johnson WC, Kappmeyer LS, Herndon DR, Mousel MR, Reif KE, Taus NS, Ifeonu OO, Silva JC, Suarez CE, Brayton KA.
PMID: 33294524
Data Brief. 2020 Nov 17;33:106533. doi: 10.1016/j.dib.2020.106533. eCollection 2020 Dec.

No abstract available.

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Ueti MW, Johnson WC, Kappmeyer LS, et al. Transcriptome dataset of . Data Brief. 2020;33:106533doi: 10.1016/j.dib.2020.106533.
Ueti, M. W., Johnson, W. C., Kappmeyer, L. S., Herndon, D. R., Mousel, M. R., Reif, K. E., Taus, N. S., Ifeonu, O. O., Silva, J. C., Suarez, C. E., & Brayton, K. A. (2020). Transcriptome dataset of . Data in brief, 33106533. https://doi.org/10.1016/j.dib.2020.106533
Ueti, Massaro W, et al. "Transcriptome dataset of ." Data in brief vol. 33 (2020): 106533. doi: https://doi.org/10.1016/j.dib.2020.106533
Ueti MW, Johnson WC, Kappmeyer LS, Herndon DR, Mousel MR, Reif KE, Taus NS, Ifeonu OO, Silva JC, Suarez CE, Brayton KA. Transcriptome dataset of . Data Brief. 2020 Nov 17;33:106533. doi: 10.1016/j.dib.2020.106533. eCollection 2020 Dec. PMID: 33294524; PMCID: PMC7701181.
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The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling.

Cell reports

Zyulina V, Yan KK, Ju B, Schwarzenberger E, Passegger C, Tam-Amersdorfer C, Pan Q, Sconocchia T, Pollack C, Shaner B, Zebisch A, Easton J, Yu J, Silva JM, Strobl H.
PMID: 33910004
Cell Rep. 2021 Apr 27;35(4):109049. doi: 10.1016/j.celrep.2021.109049.

Transforming growth factor β (TGF-β) family ligands are key regulators of dendritic cell (DC) differentiation and activation. Epidermal Langerhans cells (LCs) require TGF-β family signaling for their differentiation, and canonical TGF-β1 signaling secures a non-activated LC state. LCs reportedly...

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Zyulina V, Yan KK, Ju B, et al. The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling. Cell Rep. 2021;35(4):109049doi: 10.1016/j.celrep.2021.109049.
Zyulina, V., Yan, K. K., Ju, B., Schwarzenberger, E., Passegger, C., Tam-Amersdorfer, C., Pan, Q., Sconocchia, T., Pollack, C., Shaner, B., Zebisch, A., Easton, J., Yu, J., Silva, J. M., & Strobl, H. (2021). The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling. Cell reports, 35(4), 109049. https://doi.org/10.1016/j.celrep.2021.109049
Zyulina, Victoria, et al. "The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling." Cell reports vol. 35,4 (2021): 109049. doi: https://doi.org/10.1016/j.celrep.2021.109049
Zyulina V, Yan KK, Ju B, Schwarzenberger E, Passegger C, Tam-Amersdorfer C, Pan Q, Sconocchia T, Pollack C, Shaner B, Zebisch A, Easton J, Yu J, Silva JM, Strobl H. The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling. Cell Rep. 2021 Apr 27;35(4):109049. doi: 10.1016/j.celrep.2021.109049. PMID: 33910004.
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Using kaon regeneration to probe the quark mixing parameter cos2beta in B --> psiK decays.

Physical review letters

Quinn HR, Schietinger T, Silva JP, Snyder AE.
PMID: 11135977
Phys Rev Lett. 2000 Dec 18;85(25):5284-7. doi: 10.1103/PhysRevLett.85.5284.

We suggest a novel method to determine the sign of cos2beta in the decays B --> psiK, by creating interference between K(L) and K(S) final states via "regeneration," that is propagation through a matter target region to convert some...

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Quinn HR, Schietinger T, Silva JP, et al. Using kaon regeneration to probe the quark mixing parameter cos2beta in B --> psiK decays. Phys Rev Lett. 2000;85(25):5284-7doi: 10.1103/PhysRevLett.85.5284.
Quinn, H. R., Schietinger, T., Silva, J. P., & Snyder, A. E. (2000). Using kaon regeneration to probe the quark mixing parameter cos2beta in B --> psiK decays. Physical review letters, 85(25), 5284-7. https://doi.org/10.1103/PhysRevLett.85.5284
Quinn, H R, et al. "Using kaon regeneration to probe the quark mixing parameter cos2beta in B --> psiK decays." Physical review letters vol. 85,25 (2000): 5284-7. doi: https://doi.org/10.1103/PhysRevLett.85.5284
Quinn HR, Schietinger T, Silva JP, Snyder AE. Using kaon regeneration to probe the quark mixing parameter cos2beta in B --> psiK decays. Phys Rev Lett. 2000 Dec 18;85(25):5284-7. doi: 10.1103/PhysRevLett.85.5284. PMID: 11135977.
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Showing 901 to 910 of 910 entries