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Showing 793 to 802 of 802 entries
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Neuroleptic malignant syndrome associated with the use of injection zuclopenthixol acetate.

Industrial psychiatry journal

Shouan A, Sinha AK, Grover S.
PMID: 33776291
Ind Psychiatry J. 2020 Jan-Jun;29(1):162-164. doi: 10.4103/ipj.ipj_54_19. Epub 2020 Nov 07.

Zuclopenthixol is available in two parenteral formulation,i.e., in the form of acetate and decanoate. It has high affinity for dopamine D1 and D2 receptors. There is limited literature of association of neuroleptic malignant syndrome with the use of zuclopenthixol...

Whole Tumor Segmentation from Brain MR images using Multi-view 2D Convolutional Neural Network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Lahoti R, Vengalil SK, Venkategowda PB, Sinha N, Reddy VV.
PMID: 34892131
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:4111-4114. doi: 10.1109/EMBC46164.2021.9631035.

In this paper, a study is reported on the popular BraTS dataset for segmentation of brain tumor. The BraTS 2019 dataset is used that comprises four MR modalities along with the ground-truth for 259 high grade glioma (HGG) and...

Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress-induced mitochondrial dysfunction.

Aging cell

Cano M, Datta S, Wang L, Liu T, Flores-Bellver M, Sachdeva M, Sinha D, Handa JT.
PMID: 34313391
Aging Cell. 2021 Aug;20(8):e13444. doi: 10.1111/acel.13444. Epub 2021 Jul 27.

The nuclear factor-erythroid 2-related factor-2 (Nrf2), a major antioxidant transcription factor, is decreased in several age-related diseases including age-related macular degeneration (AMD), the most common cause of blindness among the elderly in western society. Since Nrf2's mito-protective response is...

Differences in the serum metabolic profile to identify potential biomarkers for cyanotic versus acyanotic heart disease.

Perfusion

Vimal S, Ranjan R, Yadav S, Majumdar G, Mittal B, Sinha N, Agarwal SK.
PMID: 34472991
Perfusion. 2021 Sep 02;2676591211042559. doi: 10.1177/02676591211042559. Epub 2021 Sep 02.

BACKGROUND: Growth retardation, malnutrition, and failure to thrive are some of the consequences associated with congenital heart diseases. Several metabolic factors such as hypoxia, anoxia, and several genetic factors are believed to alter the energetics of the heart. Timely...

Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population.

Journal of pharmacy & bioallied sciences

Singh AK, Chauhan R, Anand K, Singh M, Das SR, Sinha AK.
PMID: 34447119
J Pharm Bioallied Sci. 2021 Jun;13:S398-S401. doi: 10.4103/jpbs.JPBS_751_20. Epub 2021 Jun 05.

BACKGROUND: The present study was conducted to assess risk factors and prevalence of potentially malignant disorders (PMDs) among Indian population.MATERIALS AND METHODS: 1280 Indian population of both genders were enrolled. Habits such as smoking bidi, cigarette, consumption of tobacco...

Predictors of deliberate self-harm among adolescents: Answers from a cross-sectional study on India.

BMC psychology

Sinha D, Srivastava S, Mishra PS, Kumar P.
PMID: 34922635
BMC Psychol. 2021 Dec 18;9(1):197. doi: 10.1186/s40359-021-00705-4.

BACKGROUND: Although existing research supports the correlation of hereditary and psychological factors with an adolescent's deliberate self-harm, there is a dearth of research that focus on their socio-economic characteristics. This paper intends to identity the potential risk factors that...

Selective anticancer activities of ruthenium(II)-tetrazole complexes and their mechanistic insights.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Sonkar C, Malviya N, Sinha N, Mukherjee A, Pakhira S, Mukhopadhyay S.
PMID: 33900532
Biometals. 2021 Aug;34(4):795-812. doi: 10.1007/s10534-021-00308-x. Epub 2021 Apr 26.

Ruthenium-based metallotherapeutics is an interesting alternative for platinum complexes acting as anticancer agents after the entry of KP1019, NAMI-A, and TLD1339 in clinical trials. Herein, we have synthesized three new arene ruthenium(II)-tetrazole complexes viz. [Ru

Stress-induced protein dermcidin develops diabetes targeting GLUT4/insulinviaNO/cGMP inhibition.

British journal of pharmacology

Bank S, Bhattacharya S, Koschinski A, Zaccolo M, Maiti S, Banerjee A, De SK, Khan GA, Das M, Guha S, Ghosh A, Ray U, Sinha AK.
PMID: 34479399
Br J Pharmacol. 2021 Sep 03; doi: 10.1111/bph.15674. Epub 2021 Sep 03.

BACKGROUND AND PURPOSE: Diabetes is common in tobacco-consuming individuals, hypoxia-encountering people, and post-menopausal women. The mechanism behind diabetes-associated vascular-dysfunction remains speculative. Dermcidin (DCD), an 11 kDa-protein plays a detrimental role in acute myocardial-infarction through the impairment of endothelial-nitric-oxide-synthase (eNOS).EXPERIMENTAL...

Mathematical modeling of the outbreak of COVID-19.

Network modeling and analysis in health informatics and bioinformatics

Sinha AK, Namdev N, Shende P.
PMID: 34909367
Netw Model Anal Health Inform Bioinform. 2022;11(1):5. doi: 10.1007/s13721-021-00350-2. Epub 2021 Dec 10.

The novel coronavirus SARS-Cov-2 is a pandemic condition and poses a massive menace to health. The governments of different countries and their various prohibitory steps to restrict the virus's expanse have changed individuals' communication processes. Due to physical and...

Delineating the complex mechanistic interplay between NF-κβ driven mTOR depedent autophagy and monocyte to macrophage differentiation: A functional perspective.

Cellular signalling

Bhattacharya A, Ghosh P, Singh A, Ghosh A, Bhowmick A, Sinha DK, Ghosh A, Sen P.
PMID: 34547324
Cell Signal. 2021 Dec;88:110150. doi: 10.1016/j.cellsig.2021.110150. Epub 2021 Sep 20.

Autophagy is an extremely essential cellular process aimed to clear redundant and damaged materials, namely organelles, protein aggregates, invading pathogens, etc. through the formation of autophagosomes which are ultimately targeted to lysosomal degradation. In this study, we demonstrated that...

Showing 793 to 802 of 802 entries