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A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications.

SLAS discovery : advancing life sciences R & D

Stacey P, Lithgow H, Lewell X, Konopacka A, Besley S, Green G, Whatling R, Law R, Röth S, Sapkota GP, Smith IED, Burley GA, Harling J, Benowitz AB, Queisser MA, Muelbaier M.
PMID: 34041938
SLAS Discov. 2021 Aug;26(7):885-895. doi: 10.1177/24725552211017517. Epub 2021 May 27.

Targeted protein degradation is an emerging new strategy for the modulation of intracellular protein levels with applications in chemical biology and drug discovery. One approach to enable this strategy is to redirect the ubiquitin-proteasome system to mark and degrade...

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Stacey P, Lithgow H, Lewell X, et al. A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications. SLAS Discov. 2021;26(7):885-895doi: 10.1177/24725552211017517.
Stacey, P., Lithgow, H., Lewell, X., Konopacka, A., Besley, S., Green, G., Whatling, R., Law, R., Röth, S., Sapkota, G. P., Smith, I. E. D., Burley, G. A., Harling, J., Benowitz, A. B., Queisser, M. A., & Muelbaier, M. (2021). A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications. SLAS discovery : advancing life sciences R & D, 26(7), 885-895. https://doi.org/10.1177/24725552211017517
Stacey, Peter, et al. "A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications." SLAS discovery : advancing life sciences R & D vol. 26,7 (2021): 885-895. doi: https://doi.org/10.1177/24725552211017517
Stacey P, Lithgow H, Lewell X, Konopacka A, Besley S, Green G, Whatling R, Law R, Röth S, Sapkota GP, Smith IED, Burley GA, Harling J, Benowitz AB, Queisser MA, Muelbaier M. A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications. SLAS Discov. 2021 Aug;26(7):885-895. doi: 10.1177/24725552211017517. Epub 2021 May 27. PMID: 34041938.
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Controlling surface defect valence in colloids.

Physical review letters

Skacej G, Zannoni C.
PMID: 18518488
Phys Rev Lett. 2008 May 16;100(19):197802. doi: 10.1103/PhysRevLett.100.197802. Epub 2008 May 14.

We perform large-scale Monte Carlo simulations of orientational ordering in nematic shells and study the type and position of topological defects when an external electric field (homogeneous or quadrupolar) is applied. The field-induced variation of the defect number (and...

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Skacej G, Zannoni C. Controlling surface defect valence in colloids. Phys Rev Lett. 2008;100(19):197802doi: 10.1103/PhysRevLett.100.197802.
Skacej, G., & Zannoni, C. (2008). Controlling surface defect valence in colloids. Physical review letters, 100(19), 197802. https://doi.org/10.1103/PhysRevLett.100.197802
Skacej, G, and Zannoni, C. "Controlling surface defect valence in colloids." Physical review letters vol. 100,19 (2008): 197802. doi: https://doi.org/10.1103/PhysRevLett.100.197802
Skacej G, Zannoni C. Controlling surface defect valence in colloids. Phys Rev Lett. 2008 May 16;100(19):197802. doi: 10.1103/PhysRevLett.100.197802. Epub 2008 May 14. PMID: 18518488.
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Selected ion flow tube mass spectrometry analyses of stable isotopes in water: isotopic composition of H3O+ and H3O+ (H2O)3 ions in exchange reactions with water vapor.

Journal of the American Society for Mass Spectrometry

Spanel P, Smith D.
PMID: 11014448
J Am Soc Mass Spectrom. 2000 Oct;11(10):866-75. doi: 10.1016/s1044-0305(00)00157-4.

A new method has been developed for the determination of the isotope abundance ratios of deuterium, D, and oxygen-18, 18O, in water vapor (and water) using selected ion flow tube mass spectrometry (SIFT-MS). H3O+ ions are injected into the...

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Spanel P, Smith D. Selected ion flow tube mass spectrometry analyses of stable isotopes in water: isotopic composition of H3O+ and H3O+ (H2O)3 ions in exchange reactions with water vapor. J Am Soc Mass Spectrom. 2000;11(10):866-75doi: 10.1016/s1044-0305(00)00157-4.
Spanel, P., & Smith, D. (2000). Selected ion flow tube mass spectrometry analyses of stable isotopes in water: isotopic composition of H3O+ and H3O+ (H2O)3 ions in exchange reactions with water vapor. Journal of the American Society for Mass Spectrometry, 11(10), 866-75. https://doi.org/10.1016/s1044-0305(00)00157-4
Spanel, and Smith. "Selected ion flow tube mass spectrometry analyses of stable isotopes in water: isotopic composition of H3O+ and H3O+ (H2O)3 ions in exchange reactions with water vapor." Journal of the American Society for Mass Spectrometry vol. 11,10 (2000): 866-75. doi: https://doi.org/10.1016/s1044-0305(00)00157-4
Spanel P, Smith D. Selected ion flow tube mass spectrometry analyses of stable isotopes in water: isotopic composition of H3O+ and H3O+ (H2O)3 ions in exchange reactions with water vapor. J Am Soc Mass Spectrom. 2000 Oct;11(10):866-75. doi: 10.1016/s1044-0305(00)00157-4. PMID: 11014448.
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Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma.

Hepatology communications

Alcedo KP, Guerrero A, Basrur V, Fu D, Richardson ML, McLane JS, Tsou CC, Nesvizhskii AI, Welling TH, Lebrilla CB, Otey CA, Kim HJ, Omary MB, Snider NT.
PMID: 31592495
Hepatol Commun. 2019 Aug 09;3(10):1400-1414. doi: 10.1002/hep4.1410. eCollection 2019 Oct.

CD73, a cell-surface

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Alcedo KP, Guerrero A, Basrur V, et al. Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma. Hepatol Commun. 2019;3(10):1400-1414doi: 10.1002/hep4.1410.
Alcedo, K. P., Guerrero, A., Basrur, V., Fu, D., Richardson, M. L., McLane, J. S., Tsou, C. C., Nesvizhskii, A. I., Welling, T. H., Lebrilla, C. B., Otey, C. A., Kim, H. J., Omary, M. B., & Snider, N. T. (2019). Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma. Hepatology communications, 3(10), 1400-1414. https://doi.org/10.1002/hep4.1410
Alcedo, Karel P, et al. "Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma." Hepatology communications vol. 3,10 (2019): 1400-1414. doi: https://doi.org/10.1002/hep4.1410
Alcedo KP, Guerrero A, Basrur V, Fu D, Richardson ML, McLane JS, Tsou CC, Nesvizhskii AI, Welling TH, Lebrilla CB, Otey CA, Kim HJ, Omary MB, Snider NT. Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma. Hepatol Commun. 2019 Aug 09;3(10):1400-1414. doi: 10.1002/hep4.1410. eCollection 2019 Oct. PMID: 31592495; PMCID: PMC6771166.
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Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites.

Nanomaterials (Basel, Switzerland)

Pelclova D, Zdimal V, Schwarz J, Dvorackova S, Komarc M, Ondracek J, Kostejn M, Kacer P, Vlckova S, Fenclova Z, Popov A, Lischkova L, Zakharov S, Bello D.
PMID: 30103442
Nanomaterials (Basel). 2018 Aug 10;8(8). doi: 10.3390/nano8080611.

Researchers in nanocomposite processing may inhale a variety of chemical agents, including nanoparticles. This study investigated airway oxidative stress status in the exhaled breath condensate (EBC). Nineteen employees (42.4 ± 11.4 y/o), working in nanocomposites research for 18.0 ±...

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Pelclova D, Zdimal V, Schwarz J, et al. Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites. Nanomaterials (Basel). 2018;8(8)doi: 10.3390/nano8080611.
Pelclova, D., Zdimal, V., Schwarz, J., Dvorackova, S., Komarc, M., Ondracek, J., Kostejn, M., Kacer, P., Vlckova, S., Fenclova, Z., Popov, A., Lischkova, L., Zakharov, S., & Bello, D. (2018). Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites. Nanomaterials (Basel, Switzerland), 8(8), . https://doi.org/10.3390/nano8080611
Pelclova, Daniela, et al. "Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites." Nanomaterials (Basel, Switzerland) vol. 8,8 (2018). doi: https://doi.org/10.3390/nano8080611
Pelclova D, Zdimal V, Schwarz J, Dvorackova S, Komarc M, Ondracek J, Kostejn M, Kacer P, Vlckova S, Fenclova Z, Popov A, Lischkova L, Zakharov S, Bello D. Markers of Oxidative Stress in the Exhaled Breath Condensate of Workers Handling Nanocomposites. Nanomaterials (Basel). 2018 Aug 10;8(8). doi: 10.3390/nano8080611. PMID: 30103442; PMCID: PMC6116291.
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Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display.

PloS one

Skamel C, Aller SG, Bopda Waffo A.
PMID: 29944705
PLoS One. 2018 Jun 26;13(6):e0199953. doi: 10.1371/journal.pone.0199953. eCollection 2018.

[This corrects the article DOI: 10.1371/journal.pone.0113069.].

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Skamel C, Aller SG, Bopda Waffo A. Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display. PLoS One. 2018;13(6):e0199953doi: 10.1371/journal.pone.0199953.
Skamel, C., Aller, S. G., & Bopda Waffo, A. (2018). Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display. PloS one, 13(6), e0199953. https://doi.org/10.1371/journal.pone.0199953
Skamel, Claudia, et al. "Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display." PloS one vol. 13,6 (2018): e0199953. doi: https://doi.org/10.1371/journal.pone.0199953
Skamel C, Aller SG, Bopda Waffo A. Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display. PLoS One. 2018 Jun 26;13(6):e0199953. doi: 10.1371/journal.pone.0199953. eCollection 2018. PMID: 29944705; PMCID: PMC6019667.
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NanoTiO.

Nanomaterials (Basel, Switzerland)

Pelclova D, Navratil T, Kacerova T, Zamostna B, Fenclova Z, Vlckova S, Kacer P.
PMID: 31212919
Nanomaterials (Basel). 2019 Jun 17;9(6). doi: 10.3390/nano9060888.

The present pilot study tested the efficiency of nanoTiO

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Pelclova D, Navratil T, Kacerova T, et al. NanoTiO. Nanomaterials (Basel). 2019;9(6)doi: 10.3390/nano9060888.
Pelclova, D., Navratil, T., Kacerova, T., Zamostna, B., Fenclova, Z., Vlckova, S., & Kacer, P. (2019). NanoTiO. Nanomaterials (Basel, Switzerland), 9(6), . https://doi.org/10.3390/nano9060888
Pelclova, Daniela, et al. "NanoTiO." Nanomaterials (Basel, Switzerland) vol. 9,6 (2019). doi: https://doi.org/10.3390/nano9060888
Pelclova D, Navratil T, Kacerova T, Zamostna B, Fenclova Z, Vlckova S, Kacer P. NanoTiO. Nanomaterials (Basel). 2019 Jun 17;9(6). doi: 10.3390/nano9060888. PMID: 31212919; PMCID: PMC6631994.
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The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach.

Nutrition & metabolism

Markova I, Hüttl M, Oliyarnyk O, Kacerova T, Haluzik M, Kacer P, Seda O, Malinska H.
PMID: 31388341
Nutr Metab (Lond). 2019 Aug 01;16:51. doi: 10.1186/s12986-019-0376-1. eCollection 2019.

BACKGROUND AND AIMS: Dicarbonyl stress plays an important role in the pathogenesis of microvascular complications that precede the formation of advanced glycation end products, and contributes to the development of renal dysfunction. In renal cells, toxic metabolites like methylglyoxal...

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Markova I, Hüttl M, Oliyarnyk O, et al. The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach. Nutr Metab (Lond). 2019;16:51doi: 10.1186/s12986-019-0376-1.
Markova, I., Hüttl, M., Oliyarnyk, O., Kacerova, T., Haluzik, M., Kacer, P., Seda, O., & Malinska, H. (2019). The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach. Nutrition & metabolism, 1651. https://doi.org/10.1186/s12986-019-0376-1
Markova, Irena, et al. "The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach." Nutrition & metabolism vol. 16 (2019): 51. doi: https://doi.org/10.1186/s12986-019-0376-1
Markova I, Hüttl M, Oliyarnyk O, Kacerova T, Haluzik M, Kacer P, Seda O, Malinska H. The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome - a transcriptomic and proteomic approach. Nutr Metab (Lond). 2019 Aug 01;16:51. doi: 10.1186/s12986-019-0376-1. eCollection 2019. PMID: 31388341; PMCID: PMC6670216.
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Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum.

Physical review letters

Grünhaupt L, Maleeva N, Skacel ST, Calvo M, Levy-Bertrand F, Ustinov AV, Rotzinger H, Monfardini A, Catelani G, Pop IM.
PMID: 30265102
Phys Rev Lett. 2018 Sep 14;121(11):117001. doi: 10.1103/PhysRevLett.121.117001.

Superconducting high kinetic inductance elements constitute a valuable resource for quantum circuit design and millimeter-wave detection. Granular aluminum (grAl) in the superconducting regime is a particularly interesting material since it has already shown a kinetic inductance in the range...

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Grünhaupt L, Maleeva N, Skacel ST, et al. Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum. Phys Rev Lett. 2018;121(11):117001doi: 10.1103/PhysRevLett.121.117001.
Grünhaupt, L., Maleeva, N., Skacel, S. T., Calvo, M., Levy-Bertrand, F., Ustinov, A. V., Rotzinger, H., Monfardini, A., Catelani, G., & Pop, I. M. (2018). Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum. Physical review letters, 121(11), 117001. https://doi.org/10.1103/PhysRevLett.121.117001
Grünhaupt, Lukas, et al. "Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum." Physical review letters vol. 121,11 (2018): 117001. doi: https://doi.org/10.1103/PhysRevLett.121.117001
Grünhaupt L, Maleeva N, Skacel ST, Calvo M, Levy-Bertrand F, Ustinov AV, Rotzinger H, Monfardini A, Catelani G, Pop IM. Loss Mechanisms and Quasiparticle Dynamics in Superconducting Microwave Resonators Made of Thin-Film Granular Aluminum. Phys Rev Lett. 2018 Sep 14;121(11):117001. doi: 10.1103/PhysRevLett.121.117001. PMID: 30265102.
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Medicare Meaningful Use in a MACRA World.

Michigan medicine

Hettiger SP.
PMID: 30379443
Mich Med. 2017 Jan;116(1):10.

No abstract available.

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Hettiger SP. Medicare Meaningful Use in a MACRA World. Mich Med. 2017;116(1):10
Hettiger, S. P. (2017). Medicare Meaningful Use in a MACRA World. Michigan medicine, 116(1), 10.
Hettiger, Stacey P. "Medicare Meaningful Use in a MACRA World." Michigan medicine vol. 116,1 (2017): 10.
Hettiger SP. Medicare Meaningful Use in a MACRA World. Mich Med. 2017 Jan;116(1):10. PMID: 30379443.
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Combined use of gas chromatography and selected ion flow tube mass spectrometry for absolute trace gas quantification.

Rapid communications in mass spectrometry : RCM

Kubista J, Spanel P, Dryahina K, Workman C, Smith D.
PMID: 16419024
Rapid Commun Mass Spectrom. 2006;20(4):563-7. doi: 10.1002/rcm.2340.

The value of the gas chromatography (GC) and selected ion flow tube mass spectrometry (SIFT-MS) combination for the analysis of trace gases is demonstrated by the quantification of acetone in air samples using the three precursor ions available to...

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Kubista J, Spanel P, Dryahina K, et al. Combined use of gas chromatography and selected ion flow tube mass spectrometry for absolute trace gas quantification. Rapid Commun Mass Spectrom. 2006;20(4):563-7doi: 10.1002/rcm.2340.
Kubista, J., Spanel, P., Dryahina, K., Workman, C., & Smith, D. (2006). Combined use of gas chromatography and selected ion flow tube mass spectrometry for absolute trace gas quantification. Rapid communications in mass spectrometry : RCM, 20(4), 563-7. https://doi.org/10.1002/rcm.2340
Kubista, Jirí, et al. "Combined use of gas chromatography and selected ion flow tube mass spectrometry for absolute trace gas quantification." Rapid communications in mass spectrometry : RCM vol. 20,4 (2006): 563-7. doi: https://doi.org/10.1002/rcm.2340
Kubista J, Spanel P, Dryahina K, Workman C, Smith D. Combined use of gas chromatography and selected ion flow tube mass spectrometry for absolute trace gas quantification. Rapid Commun Mass Spectrom. 2006;20(4):563-7. doi: 10.1002/rcm.2340. PMID: 16419024.
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Changes in Protein Synthesis upon Cytokinin-Mediated Adventitious Bud Induction and during Seedling Development in Norway Spruce, Picea abies.

Plant physiology

Stabel P, Eriksson T, Engström P.
PMID: 16667387
Plant Physiol. 1990 Apr;92(4):1174-83. doi: 10.1104/pp.92.4.1174.

A pulse-treatment of embryos of Picea abies (L.) Karst with cytokinin efficiently and reproducibly induces the coordinate de novo formation of bud primordia from subepidermal cells. The cytokinin treatment also affects the germinative development of the embryo; chloroplast maturation...

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Stabel P, Eriksson T, Engström P. Changes in Protein Synthesis upon Cytokinin-Mediated Adventitious Bud Induction and during Seedling Development in Norway Spruce, Picea abies. Plant Physiol. 1990;92(4):1174-83doi: 10.1104/pp.92.4.1174.
Stabel, P., Eriksson, T., & Engström, P. (1990). Changes in Protein Synthesis upon Cytokinin-Mediated Adventitious Bud Induction and during Seedling Development in Norway Spruce, Picea abies. Plant physiology, 92(4), 1174-83. https://doi.org/10.1104/pp.92.4.1174
Stabel, P, et al. "Changes in Protein Synthesis upon Cytokinin-Mediated Adventitious Bud Induction and during Seedling Development in Norway Spruce, Picea abies." Plant physiology vol. 92,4 (1990): 1174-83. doi: https://doi.org/10.1104/pp.92.4.1174
Stabel P, Eriksson T, Engström P. Changes in Protein Synthesis upon Cytokinin-Mediated Adventitious Bud Induction and during Seedling Development in Norway Spruce, Picea abies. Plant Physiol. 1990 Apr;92(4):1174-83. doi: 10.1104/pp.92.4.1174. PMID: 16667387; PMCID: PMC1062432.
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Showing 13 to 24 of 105 entries