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Showing 13 to 24 of 50 entries
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Histamine and the classic antihistamines.

Drug news & perspectives

Sneader W.
PMID: 12806427
Drug News Perspect. 2001 Dec;14(10):618-24.

The first steps leading to the recognition of histamine's biological activity were taken in 1907. The existence of histamine in the body was finally recognized by 1910, and many researchers were keen to establish its physiological role, especially with...

Epinephrine analogues.

Drug news & perspectives

Sneader W.
PMID: 12806441
Drug News Perspect. 2001 Nov;14(9):539-43. doi: 10.1358/dnp.2001.14.9.858410.

Tyramine was the first epinephrine analogue to be introduced into medicine, in the early 1900s. It was followed by ephedrine and pseudoephedrine in the 1920s and by the amfetamines a decade later. The popularity of the amfetamines grew throughout...

Decorating graphene with size-selected few-atom clusters: a novel approach to investigate graphene-adparticle interactions.

Nanoscale

Scheerder JE, Picot T, Reckinger N, Sneyder T, Zharinov VS, Colomer JF, Janssens E, Van de Vondel J.
PMID: 28703819
Nanoscale. 2017 Jul 27;9(29):10494-10501. doi: 10.1039/c7nr02217d.

We investigated the interaction between size-selected Au

The prehistory of psychotherapeutic agents.

Journal of psychopharmacology (Oxford, England)

Sneader W.
PMID: 22282937
J Psychopharmacol. 1990 Jan;4(3):115-9. doi: 10.1177/026988119000400303.

In the absence of a coherent understanding of the pathological basis of a disease, only serendipity can provide effective drugs for its treatment. Nowhere is this more evident than in an examination of the history of psychotherapeutic drugs (Sneader,...

Hydrothermal synthesis and spectroscopic properties of a new glaserite material, K3RE(VO4)2 (RE = Sc, Y, Dy, Ho, Er, Yb, Lu, or Tm) with potential lasing and optical properties.

Inorganic chemistry

Kimani MM, Thompson L, Snider W, McMillen CD, Kolis JW.
PMID: 23205611
Inorg Chem. 2012 Dec 17;51(24):13271-80. doi: 10.1021/ic301922e. Epub 2012 Dec 03.

A new series of materials of the glaserite family with the general formula K(3)RE(VO(4))(2)(RE = Sc, Y, Dy, Ho, Er, Tm, Yb, and Lu) have been hydrothermally synthesized using 10 M K(2)CO(3) at 560 °C and characterized by single...

Interactions of fluorescent cholinergic antagonists with the membrane-bound acetylcholine receptor.

Neurochemistry international

Tan YP, Stender W, Harvey AL, Soria B, Barrantes FJ.
PMID: 20487792
Neurochem Int. 1980;2:257-67. doi: 10.1016/0197-0186(80)90033-9.

The synthesis of pyrenyl-choline derivatives is reported. The interactions of these compounds with the acetylcholine receptor has been studied in developing chick myotubes in culture and in the adult frog neuromuscular junction with electrophysiological techniques. In vivo, the compounds...

A population K-PD model analysis of long-term testosterone inhibition in prostate cancer patients undergoing intermittent androgen deprivation therapy.

Journal of pharmacokinetics and pharmacodynamics

DeJongh J, Ahsman M, Snelder N.
PMID: 33538922
J Pharmacokinet Pharmacodyn. 2021 Aug;48(4):465-477. doi: 10.1007/s10928-020-09736-7. Epub 2021 Feb 04.

Intermittent androgen deprivation therapy with gonadotropin-releasing-hormone (GnRH) agonists can prevent or delay disease progression and development of castration resistant prostate cancer for subpopulations of prostate cancer patients. It may also reduce risk and severity of side effects associated with...

The expression, localisation and interactome of pigeon CRY2.

Scientific reports

Balay SD, Hochstoeger T, Vilceanu A, Malkemper EP, Snider W, Dürnberger G, Mechtler K, Schuechner S, Ogris E, Nordmann GC, Ushakova L, Nimpf S, Keays DA.
PMID: 34645873
Sci Rep. 2021 Oct 13;11(1):20293. doi: 10.1038/s41598-021-99207-x.

Cryptochromes (CRY) are highly conserved signalling molecules that regulate circadian rhythms and are candidate radical pair based magnetoreceptors. Birds have at least four cryptochromes (CRY1a, CRY1b, CRY2, and CRY4), but few studies have interrogated their function. Here we investigate...

Successful delivery after vaginal occlusion in addition to cerclage in a trachelectomy patient with recurrent second trimester pregnancy loss: a case report.

Clinical case reports

Sneider K, Poulsen MØ, Ottosen C, Langhoff-Roos J.
PMID: 25356275
Clin Case Rep. 2014 Aug;2(4):153-5. doi: 10.1002/ccr3.84. Epub 2014 Jun 03.

KEY CLINICAL MESSAGE: Pregnancy outcome after trachelectomy has high risk of complications such as second trimester pregnancy loss and preterm birth. We report beneficial effect of a simple procedure of vaginal occlusion in addition to cerclage in a patient...

Use of the p-values as a size-dependent function to address practical differences when analyzing large datasets.

Scientific reports

Gómez-de-Mariscal E, Guerrero V, Sneider A, Jayatilaka H, Phillip JM, Wirtz D, Muñoz-Barrutia A.
PMID: 34686696
Sci Rep. 2021 Oct 22;11(1):20942. doi: 10.1038/s41598-021-00199-5.

Biomedical research has come to rely on p-values as a deterministic measure for data-driven decision-making. In the largely extended null hypothesis significance testing for identifying statistically significant differences among groups of observations, a single p-value is computed from sample...

The expression, localisation and interactome of pigeon CRY2.

Scientific reports

Balay SD, Hochstoeger T, Vilceanu A, Malkemper EP, Snider W, Dürnberger G, Mechtler K, Schuechner S, Ogris E, Nordmann GC, Ushakova L, Nimpf S, Keays DA.
PMID: 34645873
Sci Rep. 2021 Oct 13;11(1):20293. doi: 10.1038/s41598-021-99207-x.

Cryptochromes (CRY) are highly conserved signalling molecules that regulate circadian rhythms and are candidate radical pair based magnetoreceptors. Birds have at least four cryptochromes (CRY1a, CRY1b, CRY2, and CRY4), but few studies have interrogated their function. Here we investigate...

PK/PD modeling of FXI antisense oligonucleotides to bridge the dose-FXI activity relation from healthy volunteers to end-stage renal disease patients.

CPT: pharmacometrics & systems pharmacology

Willmann S, Marostica E, Snelder N, Solms A, Jensen M, Lobmeyer M, Lensing AWA, Bethune C, Morgan E, Yu RZ, Wang Y, Jung SW, Geary R, Bhanot S.
PMID: 34085768
CPT Pharmacometrics Syst Pharmacol. 2021 Aug;10(8):890-901. doi: 10.1002/psp4.12663. Epub 2021 Jun 23.

IONIS-FXI

Showing 13 to 24 of 50 entries