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Showing 157 to 166 of 166 entries
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A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps.

Microbiology spectrum

Delgado S, Perales C, García-Crespo C, Soria ME, Gallego I, de Ávila AI, Martínez-González B, Vázquez-Sirvent L, López-Galíndez C, Morán F, Domingo E.
PMID: 34756074
Microbiol Spectr. 2021 Dec 22;9(3):e0145921. doi: 10.1128/Spectrum.01459-21. Epub 2021 Nov 10.

RNA viruses replicate as complex mutant spectra termed viral quasispecies. The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble. The advent of deep...

Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce.

Critical care medicine

Menon K, Schlapbach LJ, Akech S, Argent A, Biban P, Carrol ED, Chiotos K, Jobayer Chisti M, Evans IVR, Inwald DP, Ishimine P, Kissoon N, Lodha R, Nadel S, Oliveira CF, Peters M, Sadeghirad B, Scott HF, de Souza DC, Tissieres P, Watson RS, Wiens MO, Wynn JL, Zimmerman JJ, Sorce LR.
PMID: 34612847
Crit Care Med. 2021 Oct 06; doi: 10.1097/CCM.0000000000005294. Epub 2021 Oct 06.

OBJECTIVE: To determine the associations of demographic, clinical, laboratory, organ dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic shock in children with infection and 2) multiple organ dysfunction or death in children with sepsis,...

A Neglected Parasite: .

Frontiers in veterinary science

Migliore S, Puleio R, Gaglio G, Vicari D, Seminara S, Sicilia ER, Galluzzo P, Cumbo V, Loria GR.
PMID: 33996983
Front Vet Sci. 2021 Apr 28;8:659306. doi: 10.3389/fvets.2021.659306. eCollection 2021.

Sanitary management and population control of feral pigs remains a major problem in public health, particularly in natural parks where hunting is prohibited and the extensive farming of livestock is common.

Incorporating genetic and clinical data into the prediction of thromboembolism risk in patients with lymphoma.

Cancer medicine

Bastos-Oreiro M, Ortiz J, Pradillo V, Salas E, Marínez-Laperche C, Muñoz A, Buño I, Diéz-Martin JL, Soria JM, Pascual Izquierdo C.
PMID: 34598309
Cancer Med. 2021 Nov;10(21):7585-7592. doi: 10.1002/cam4.4280. Epub 2021 Oct 01.

BACKGROUND: The incorporation of genetic variables into risk scores for predicting venous thromboembolic events (VTE) could improve their capacity to identify those patients for whom thromboprophylaxis would be most beneficial. Proof-of-concept of this is provided by the TiC-ONCO score...

Study of Quasispecies Complexity and Liver Damage Progression after Liver Transplantation in Hepatitis C Virus Infected Patients.

Genes

Llorens-Revull M, Gregori J, Dopazo C, Rodriguez-Frías F, Garcia-Cehic D, Soria ME, Chen Q, Rando A, Perales C, Esteban JI, Quer J, Bilbao I.
PMID: 34828337
Genes (Basel). 2021 Oct 28;12(11). doi: 10.3390/genes12111731.

Cirrhosis derived from chronic hepatitis C virus (HCV) infection is still a common indication for liver transplantation (LT). Reinfection of the engrafted liver is universal in patients with detectable viral RNA at the time of transplant and causes fast...

Building bridges between drug development and cancer science: a tribute to José Baselga's legacy.

Annals of oncology : official journal of the European Society for Medical Oncology

Hyman DM, Soria JC, Tabernero J.
PMID: 33838220
Ann Oncol. 2021 Jul;32(7):825-828. doi: 10.1016/j.annonc.2021.03.209. Epub 2021 Apr 07.

No abstract available.

Cytotoxicity and DNA damage evaluation of TiO.

Toxicology research

Freire K, Ordóñez Ramos F, Soria DB, Pabón Gelves E, Di Virgilio AL.
PMID: 33884170
Toxicol Res (Camb). 2021 Mar 09;10(2):192-202. doi: 10.1093/toxres/tfaa112. eCollection 2021 Mar.

The cytotoxicity and DNA damage of titanium dioxide and zinc oxide nanoparticles (TiO

Overcoming Resistance to Tumor-Targeted and Immune-Targeted Therapies.

Cancer discovery

Aldea M, Andre F, Marabelle A, Dogan S, Barlesi F, Soria JC.
PMID: 33811122
Cancer Discov. 2021 Apr;11(4):874-899. doi: 10.1158/2159-8290.CD-20-1638.

Resistance to anticancer therapies includes primary resistance, usually related to lack of target dependency or presence of additional targets, and secondary resistance, mostly driven by adaptation of the cancer cell to the selection pressure of treatment. Resistance to targeted...

The social class barriers to engagement in leadership experiences.

New directions for student leadership

Soria KM.
PMID: 33871937
New Dir Stud Leadersh. 2021 Mar;2021(169):33-41. doi: 10.1002/yd.20418.

This chapter examines the barriers that prohibit poor and working-class students from accessing and engaging in leadership development experiences. Suggestions to inventory these costs and reshape leadership education to be more inclusive to students from poor or working-class backgrounds...

Calmodulin binds the N-terminus of the functional amyloid Orb2A inhibiting fibril formation.

PloS one

Soria MA, Cervantes SA, Siemer AB.
PMID: 35025866
PLoS One. 2022 Jan 13;17(1):e0259872. doi: 10.1371/journal.pone.0259872. eCollection 2022.

The cytoplasmic polyadenylation element-binding protein Orb2 is a key regulator of long-term memory (LTM) in Drosophila. The N-terminus of the Orb2 isoform A is required for LTM and forms cross-β fibrils on its own. However, this N-terminus is not...

Showing 157 to 166 of 166 entries