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Diacetyl exposure disrupts iron homeostasis in animals and cells.

Inhalation toxicology

Ghio AJ, Soukup JM, Dailey LA, Roggli VL, Crumbliss AL, Palmer SM.
PMID: 34752160
Inhal Toxicol. 2021 May-Jul;33(6):268-274. doi: 10.1080/08958378.2021.1989092. Epub 2021 Nov 09.

OBJECTIVE: Several mechanisms have been proposed for the biological effect of diacetyl. We tested the postulate that animal and cell exposures to diacetyl are associated with a disruption in iron homeostasis.MATERIALS AND METHODS: Male, Sprague-Dawley rats were intratracheally-instilled with...

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Ghio AJ, Soukup JM, Dailey LA, et al. Diacetyl exposure disrupts iron homeostasis in animals and cells. Inhal Toxicol. 2021;33(6):268-274doi: 10.1080/08958378.2021.1989092.
Ghio, A. J., Soukup, J. M., Dailey, L. A., Roggli, V. L., Crumbliss, A. L., & Palmer, S. M. (2021). Diacetyl exposure disrupts iron homeostasis in animals and cells. Inhalation toxicology, 33(6), 268-274. https://doi.org/10.1080/08958378.2021.1989092
Ghio, Andrew J, et al. "Diacetyl exposure disrupts iron homeostasis in animals and cells." Inhalation toxicology vol. 33,6 (2021): 268-274. doi: https://doi.org/10.1080/08958378.2021.1989092
Ghio AJ, Soukup JM, Dailey LA, Roggli VL, Crumbliss AL, Palmer SM. Diacetyl exposure disrupts iron homeostasis in animals and cells. Inhal Toxicol. 2021 May-Jul;33(6):268-274. doi: 10.1080/08958378.2021.1989092. Epub 2021 Nov 09. PMID: 34752160.
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Iron and zinc homeostases in female rats with physically active and sedentary lifestyles.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Ghio AJ, Soukup JM, Ghio C, Gordon CJ, Richards JE, Schladweiler MC, Snow SJ, Kodavanti UP.
PMID: 33237470
Biometals. 2021 Feb;34(1):97-105. doi: 10.1007/s10534-020-00266-w. Epub 2020 Nov 25.

To determine the effects of repeated physical activity on iron and zinc homeostases in a living system, we quantified blood and tissue levels of these two metals in sedentary and physically active Long-Evans rats. At post-natal day (PND) 22,...

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Ghio AJ, Soukup JM, Ghio C, et al. Iron and zinc homeostases in female rats with physically active and sedentary lifestyles. Biometals. 2020;34(1):97-105doi: 10.1007/s10534-020-00266-w.
Ghio, A. J., Soukup, J. M., Ghio, C., Gordon, C. J., Richards, J. E., Schladweiler, M. C., Snow, S. J., & Kodavanti, U. P. (2021). Iron and zinc homeostases in female rats with physically active and sedentary lifestyles. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 34(1), 97-105. https://doi.org/10.1007/s10534-020-00266-w
Ghio, Andrew J, et al. "Iron and zinc homeostases in female rats with physically active and sedentary lifestyles." Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine vol. 34,1 (2021): 97-105. doi: https://doi.org/10.1007/s10534-020-00266-w
Ghio AJ, Soukup JM, Ghio C, Gordon CJ, Richards JE, Schladweiler MC, Snow SJ, Kodavanti UP. Iron and zinc homeostases in female rats with physically active and sedentary lifestyles. Biometals. 2021 Feb;34(1):97-105. doi: 10.1007/s10534-020-00266-w. Epub 2020 Nov 25. PMID: 33237470; PMCID: PMC8299713.
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A measure of case complexity for streamlining workflow in multidisciplinary tumor boards: Mixed methods development and early validation of the MeDiC tool.

Cancer medicine

Soukup T, Morbi A, Lamb BW, Gandamihardja TAK, Hogben K, Noyes K, Skolarus TA, Darzi A, Sevdalis N, Green JSA.
PMID: 32476281
Cancer Med. 2020 Jul;9(14):5143-5154. doi: 10.1002/cam4.3026. Epub 2020 May 31.

BACKGROUND AND OBJECTIVE: There is increasing emphasis in cancer care globally for care to be reviewed and managed by multidisciplinary teams (ie, in tumor boards). Evidence and recommendations suggest that the complexity of each patient case needs to be...

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Soukup T, Morbi A, Lamb BW, et al. A measure of case complexity for streamlining workflow in multidisciplinary tumor boards: Mixed methods development and early validation of the MeDiC tool. Cancer Med. 2020;9(14):5143-5154doi: 10.1002/cam4.3026.
Soukup, T., Morbi, A., Lamb, B. W., Gandamihardja, T. A. K., Hogben, K., Noyes, K., Skolarus, T. A., Darzi, A., Sevdalis, N., & Green, J. S. A. (2020). A measure of case complexity for streamlining workflow in multidisciplinary tumor boards: Mixed methods development and early validation of the MeDiC tool. Cancer medicine, 9(14), 5143-5154. https://doi.org/10.1002/cam4.3026
Soukup, Tayana, et al. "A measure of case complexity for streamlining workflow in multidisciplinary tumor boards: Mixed methods development and early validation of the MeDiC tool." Cancer medicine vol. 9,14 (2020): 5143-5154. doi: https://doi.org/10.1002/cam4.3026
Soukup T, Morbi A, Lamb BW, Gandamihardja TAK, Hogben K, Noyes K, Skolarus TA, Darzi A, Sevdalis N, Green JSA. A measure of case complexity for streamlining workflow in multidisciplinary tumor boards: Mixed methods development and early validation of the MeDiC tool. Cancer Med. 2020 Jul;9(14):5143-5154. doi: 10.1002/cam4.3026. Epub 2020 May 31. PMID: 32476281; PMCID: PMC7367630.
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Rare Case of Traumatic Anterior Knee Dislocation of Total Knee Arthroplasty With a Serious Neurovascular Injury.

Arthroplasty today

Novotny T, Vanaskova E, Soukup J.
PMID: 34409140
Arthroplast Today. 2021 Aug 09;10:171-174. doi: 10.1016/j.artd.2021.06.019. eCollection 2021 Aug.

Traumatic anterior dislocation of a total knee arthroplasty (TKA) is an extremely rare occurrence. There are only a few known cases of this type of dislocation which discuss the high risk of a neurovascular complication. This article describes a...

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Novotny T, Vanaskova E, Soukup J. Rare Case of Traumatic Anterior Knee Dislocation of Total Knee Arthroplasty With a Serious Neurovascular Injury. Arthroplast Today. 2021;10:171-174doi: 10.1016/j.artd.2021.06.019.
Novotny, T., Vanaskova, E., & Soukup, J. (2021). Rare Case of Traumatic Anterior Knee Dislocation of Total Knee Arthroplasty With a Serious Neurovascular Injury. Arthroplasty today, 10171-174. https://doi.org/10.1016/j.artd.2021.06.019
Novotny, Tomas, et al. "Rare Case of Traumatic Anterior Knee Dislocation of Total Knee Arthroplasty With a Serious Neurovascular Injury." Arthroplasty today vol. 10 (2021): 171-174. doi: https://doi.org/10.1016/j.artd.2021.06.019
Novotny T, Vanaskova E, Soukup J. Rare Case of Traumatic Anterior Knee Dislocation of Total Knee Arthroplasty With a Serious Neurovascular Injury. Arthroplast Today. 2021 Aug 09;10:171-174. doi: 10.1016/j.artd.2021.06.019. eCollection 2021 Aug. PMID: 34409140; PMCID: PMC8361220.
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Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D.

Biomolecules

Juza R, Stefkova K, Dehaen W, Randakova A, Petrasek T, Vojtechova I, Kobrlova T, Pulkrabkova L, Muckova L, Mecava M, Prchal L, Mezeiova E, Musilek K, Soukup O, Korabecny J.
PMID: 34572475
Biomolecules. 2021 Aug 24;11(9). doi: 10.3390/biom11091262.

In this pilot study, a series of new 3,4-dihydroquinolin-2(1

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Juza R, Stefkova K, Dehaen W, et al. Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D. Biomolecules. 2021;11(9)doi: 10.3390/biom11091262.
Juza, R., Stefkova, K., Dehaen, W., Randakova, A., Petrasek, T., Vojtechova, I., Kobrlova, T., Pulkrabkova, L., Muckova, L., Mecava, M., Prchal, L., Mezeiova, E., Musilek, K., Soukup, O., & Korabecny, J. (2021). Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D. Biomolecules, 11(9), . https://doi.org/10.3390/biom11091262
Juza, Radomir, et al. "Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D." Biomolecules vol. 11,9 (2021). doi: https://doi.org/10.3390/biom11091262
Juza R, Stefkova K, Dehaen W, Randakova A, Petrasek T, Vojtechova I, Kobrlova T, Pulkrabkova L, Muckova L, Mecava M, Prchal L, Mezeiova E, Musilek K, Soukup O, Korabecny J. Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D. Biomolecules. 2021 Aug 24;11(9). doi: 10.3390/biom11091262. PMID: 34572475; PMCID: PMC8464836.
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Glycidyl and Methyl Methacrylate UV-Grafted PDMS Membrane Modification toward Tramadol Membrane Selectivity.

Membranes

Bourassi M, Pasichnyk M, Oesch O, Sundararajan S, Trávničková T, Soukup K, Kasher R, Gaálová J.
PMID: 34677519
Membranes (Basel). 2021 Sep 30;11(10). doi: 10.3390/membranes11100752.

Pharmaceutical wastewater pollution has reached an alarming stage, as many studies have reported. Membrane separation has shown great performance in wastewater treatment, but there are some drawbacks and undesired byproducts of this process. Selective membranes could be used for...

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Bourassi M, Pasichnyk M, Oesch O, et al. Glycidyl and Methyl Methacrylate UV-Grafted PDMS Membrane Modification toward Tramadol Membrane Selectivity. Membranes (Basel). 2021;11(10)doi: 10.3390/membranes11100752.
Bourassi, M., Pasichnyk, M., Oesch, O., Sundararajan, S., Trávničková, T., Soukup, K., Kasher, R., & Gaálová, J. (2021). Glycidyl and Methyl Methacrylate UV-Grafted PDMS Membrane Modification toward Tramadol Membrane Selectivity. Membranes, 11(10), . https://doi.org/10.3390/membranes11100752
Bourassi, Mahdi, et al. "Glycidyl and Methyl Methacrylate UV-Grafted PDMS Membrane Modification toward Tramadol Membrane Selectivity." Membranes vol. 11,10 (2021). doi: https://doi.org/10.3390/membranes11100752
Bourassi M, Pasichnyk M, Oesch O, Sundararajan S, Trávničková T, Soukup K, Kasher R, Gaálová J. Glycidyl and Methyl Methacrylate UV-Grafted PDMS Membrane Modification toward Tramadol Membrane Selectivity. Membranes (Basel). 2021 Sep 30;11(10). doi: 10.3390/membranes11100752. PMID: 34677519; PMCID: PMC8538421.
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Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease.

Phytochemistry

Vrabec R, Maříková J, Ločárek M, Korábečný J, Hulcová D, Hošťálková A, Kuneš J, Chlebek J, Kučera T, Hrabinová M, Jun D, Soukup O, Andrisano V, Jenčo J, Šafratová M, Nováková L, Opletal L, Cahlíková L.
PMID: 34798410
Phytochemistry. 2022 Feb;194:113017. doi: 10.1016/j.phytochem.2021.113017. Epub 2021 Nov 16.

One undescribed indole alkaloid together with twenty-two known compounds have been isolated from aerial parts of Vinca minor L. (Apocynaceae). The chemical structures of the isolated alkaloids were determined by a combination of MS, HRMS, 1D, and 2D NMR...

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Vrabec R, Maříková J, Ločárek M, et al. Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease. Phytochemistry. 2021;194:113017doi: 10.1016/j.phytochem.2021.113017.
Vrabec, R., Maříková, J., Ločárek, M., Korábečný, J., Hulcová, D., Hošťálková, A., Kuneš, J., Chlebek, J., Kučera, T., Hrabinová, M., Jun, D., Soukup, O., Andrisano, V., Jenčo, J., Šafratová, M., Nováková, L., Opletal, L., & Cahlíková, L. (2022). Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease. Phytochemistry, 194113017. https://doi.org/10.1016/j.phytochem.2021.113017
Vrabec, Rudolf, et al. "Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease." Phytochemistry vol. 194 (2022): 113017. doi: https://doi.org/10.1016/j.phytochem.2021.113017
Vrabec R, Maříková J, Ločárek M, Korábečný J, Hulcová D, Hošťálková A, Kuneš J, Chlebek J, Kučera T, Hrabinová M, Jun D, Soukup O, Andrisano V, Jenčo J, Šafratová M, Nováková L, Opletal L, Cahlíková L. Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease. Phytochemistry. 2022 Feb;194:113017. doi: 10.1016/j.phytochem.2021.113017. Epub 2021 Nov 16. PMID: 34798410.
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Metabolism of glyphosate by the human fecal microbiota.

Toxicology letters

Huch M, Stoll DA, Kulling SE, Soukup ST.
PMID: 34933076
Toxicol Lett. 2021 Dec 18; doi: 10.1016/j.toxlet.2021.12.013. Epub 2021 Dec 18.

Glyphosate is the most frequently used herbicide worldwide and its application is under discussion due to health concerns. As humans may be exposed to glyphosate, the present study investigated the metabolism of glyphosate by the human fecal microbiota in...

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Huch M, Stoll DA, Kulling SE, et al. Metabolism of glyphosate by the human fecal microbiota. Toxicol Lett. 2021;doi: 10.1016/j.toxlet.2021.12.013.
Huch, M., Stoll, D. A., Kulling, S. E., & Soukup, S. T. (2021). Metabolism of glyphosate by the human fecal microbiota. Toxicology letters, . https://doi.org/10.1016/j.toxlet.2021.12.013
Huch, Melanie, et al. "Metabolism of glyphosate by the human fecal microbiota." Toxicology letters vol. (2021). doi: https://doi.org/10.1016/j.toxlet.2021.12.013
Huch M, Stoll DA, Kulling SE, Soukup ST. Metabolism of glyphosate by the human fecal microbiota. Toxicol Lett. 2021 Dec 18; doi: 10.1016/j.toxlet.2021.12.013. Epub 2021 Dec 18. PMID: 34933076.
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Atom interferometry with quantized light pulses.

The Journal of chemical physics

Soukup K, Di Pumpo F, Aßmann T, Schleich WP, Giese E.
PMID: 33940824
J Chem Phys. 2021 Apr 28;154(16):164310. doi: 10.1063/5.0048806.

The far-field patterns of atoms diffracted from a classical light field or from a quantum one in a photon-number state are identical. On the other hand, diffraction from a field in a coherent state, which shares many properties with...

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Soukup K, Di Pumpo F, Aßmann T, et al. Atom interferometry with quantized light pulses. J Chem Phys. 2021;154(16):164310doi: 10.1063/5.0048806.
Soukup, K., Di Pumpo, F., Aßmann, T., Schleich, W. P., & Giese, E. (2021). Atom interferometry with quantized light pulses. The Journal of chemical physics, 154(16), 164310. https://doi.org/10.1063/5.0048806
Soukup, Katharina, et al. "Atom interferometry with quantized light pulses." The Journal of chemical physics vol. 154,16 (2021): 164310. doi: https://doi.org/10.1063/5.0048806
Soukup K, Di Pumpo F, Aßmann T, Schleich WP, Giese E. Atom interferometry with quantized light pulses. J Chem Phys. 2021 Apr 28;154(16):164310. doi: 10.1063/5.0048806. PMID: 33940824.
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AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning.

Translational vision science & technology

Deng W, Hedberg-Buenz A, Soukup DA, Taghizadeh S, Wang K, Anderson MG, Garvin MK.
PMID: 34932117
Transl Vis Sci Technol. 2021 Dec 01;10(14):22. doi: 10.1167/tvst.10.14.22.

PURPOSE: Optic nerve damage is the principal feature of glaucoma and contributes to vision loss in many diseases. In animal models, nerve health has traditionally been assessed by human experts that grade damage qualitatively or manually quantify axons from...

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Deng W, Hedberg-Buenz A, Soukup DA, et al. AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning. Transl Vis Sci Technol. 2021;10(14):22doi: 10.1167/tvst.10.14.22.
Deng, W., Hedberg-Buenz, A., Soukup, D. A., Taghizadeh, S., Wang, K., Anderson, M. G., & Garvin, M. K. (2021). AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning. Translational vision science & technology, 10(14), 22. https://doi.org/10.1167/tvst.10.14.22
Deng, Wenxiang, et al. "AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning." Translational vision science & technology vol. 10,14 (2021): 22. doi: https://doi.org/10.1167/tvst.10.14.22
Deng W, Hedberg-Buenz A, Soukup DA, Taghizadeh S, Wang K, Anderson MG, Garvin MK. AxonDeep: Automated Optic Nerve Axon Segmentation in Mice With Deep Learning. Transl Vis Sci Technol. 2021 Dec 01;10(14):22. doi: 10.1167/tvst.10.14.22. PMID: 34932117.
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Social mating system affects the frequency of extra-pair paternity in house wrens.

Animal behaviour

Soukup SS, Thompson CF.
PMID: 9398365
Anim Behav. 1997 Nov;54(5):1089-105. doi: 10.1006/anbe.1997.0556.

We tested two hypotheses regarding the effect of the social mating system on extra-pair paternity in an Illinois population of house wrens, Troglodytes aedonAccording to the genetic-quality hypothesis, polygynous males are of higher quality than monogamists, and monogamously paired...

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Soukup SS, Thompson CF. Social mating system affects the frequency of extra-pair paternity in house wrens. Anim Behav. 1997;54(5):1089-105doi: 10.1006/anbe.1997.0556.
Soukup, S. S., & Thompson, C. F. (1997). Social mating system affects the frequency of extra-pair paternity in house wrens. Animal behaviour, 54(5), 1089-105. https://doi.org/10.1006/anbe.1997.0556
Soukup, and Thompson. "Social mating system affects the frequency of extra-pair paternity in house wrens." Animal behaviour vol. 54,5 (1997): 1089-105. doi: https://doi.org/10.1006/anbe.1997.0556
Soukup SS, Thompson CF. Social mating system affects the frequency of extra-pair paternity in house wrens. Anim Behav. 1997 Nov;54(5):1089-105. doi: 10.1006/anbe.1997.0556. PMID: 9398365.
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Parity violation in proton-proton scattering at 221 MeV.

Physical review letters

Berdoz AR, Birchall J, Bland JB, Bowman JD, Campbell JR, Coombes GH, Davis CA, Green AA, Green PW, Hamian AA, Helmer R, Kadantsev S, Kuznetsov Y, Lee L, Levy CD, Mischke RE, Page SA, Ramsay WD, Reitzner SD, Ries T, Roy G, Sekulovich AM, Soukup J, Stinson GM, Stocki TJ, Sum V, Titov NA, van Oers WT, Woo RJ, Zadorozny S, Zelenski AN.
PMID: 11800873
Phys Rev Lett. 2001 Dec 31;87(27):272301. doi: 10.1103/PhysRevLett.87.272301. Epub 2001 Dec 12.

The parity-violating longitudinal analyzing power, A(z), has been measured in pvectorp elastic scattering at an incident proton energy of 221 MeV. The result obtained is A(z) = [0.84+/-0.29(stat)+/-0.17(syst)]x10(-7). This experiment is unique in that it selects a single parity...

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Berdoz AR, Birchall J, Bland JB, et al. Parity violation in proton-proton scattering at 221 MeV. Phys Rev Lett. 2001;87(27):272301doi: 10.1103/PhysRevLett.87.272301.
Berdoz, A. R., Birchall, J., Bland, J. B., Bowman, J. D., Campbell, J. R., Coombes, G. H., Davis, C. A., Green, A. A., Green, P. W., Hamian, A. A., Helmer, R., Kadantsev, S., Kuznetsov, Y., Lee, L., Levy, C. D., Mischke, R. E., Page, S. A., Ramsay, W. D., Reitzner, S. D., Ries, T., Roy, G., Sekulovich, A. M., Soukup, J., Stinson, G. M., Stocki, T. J., Sum, V., Titov, N. A., van Oers, W. T., Woo, R. J., Zadorozny, S., Zelenski, A. N. (2001). Parity violation in proton-proton scattering at 221 MeV. Physical review letters, 87(27), 272301. https://doi.org/10.1103/PhysRevLett.87.272301
Berdoz, A R, et al. "Parity violation in proton-proton scattering at 221 MeV." Physical review letters vol. 87,27 (2001): 272301. doi: https://doi.org/10.1103/PhysRevLett.87.272301
Berdoz AR, Birchall J, Bland JB, Bowman JD, Campbell JR, Coombes GH, Davis CA, Green AA, Green PW, Hamian AA, Helmer R, Kadantsev S, Kuznetsov Y, Lee L, Levy CD, Mischke RE, Page SA, Ramsay WD, Reitzner SD, Ries T, Roy G, Sekulovich AM, Soukup J, Stinson GM, Stocki TJ, Sum V, Titov NA, van Oers WT, Woo RJ, Zadorozny S, Zelenski AN. Parity violation in proton-proton scattering at 221 MeV. Phys Rev Lett. 2001 Dec 31;87(27):272301. doi: 10.1103/PhysRevLett.87.272301. Epub 2001 Dec 12. PMID: 11800873.
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