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Showing 1897 to 1901 of 1901 entries
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SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis.

Cell reports

Portillo M, Eremenko E, Kaluski S, Garcia-Venzor A, Onn L, Stein D, Slobodnik Z, Zaretsky A, Ueberham U, Einav M, Brückner MK, Arendt T, Toiber D.
PMID: 33910019
Cell Rep. 2021 Apr 27;35(4):109035. doi: 10.1016/j.celrep.2021.109035.

Several neurodegenerative diseases present Tau accumulation as the main pathological marker. Tau post-translational modifications such as phosphorylation and acetylation are increased in neurodegeneration. Here, we show that Tau hyper-acetylation at residue 174 increases its own nuclear presence and is...

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Portillo M, Eremenko E, Kaluski S, et al. SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis. Cell Rep. 2021;35(4):109035doi: 10.1016/j.celrep.2021.109035.
Portillo, M., Eremenko, E., Kaluski, S., Garcia-Venzor, A., Onn, L., Stein, D., Slobodnik, Z., Zaretsky, A., Ueberham, U., Einav, M., Brückner, M. K., Arendt, T., & Toiber, D. (2021). SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis. Cell reports, 35(4), 109035. https://doi.org/10.1016/j.celrep.2021.109035
Portillo, Miguel, et al. "SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis." Cell reports vol. 35,4 (2021): 109035. doi: https://doi.org/10.1016/j.celrep.2021.109035
Portillo M, Eremenko E, Kaluski S, Garcia-Venzor A, Onn L, Stein D, Slobodnik Z, Zaretsky A, Ueberham U, Einav M, Brückner MK, Arendt T, Toiber D. SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis. Cell Rep. 2021 Apr 27;35(4):109035. doi: 10.1016/j.celrep.2021.109035. PMID: 33910019.
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Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study.

JAMA pediatrics

Villar J, Restrepo-Méndez MC, McGready R, Barros FC, Victora CG, Munim S, Papageorghiou AT, Ochieng R, Craik R, Barsosio HC, Berkley JA, Carvalho M, Fernandes M, Cheikh Ismail L, Lambert A, Norris SA, Ohuma EO, Stein A, Tshivuila-Matala COO, Zondervan KT, Winsey A, Nosten F, Uauy R, Bhutta ZA, Kennedy SH.
PMID: 33646288
JAMA Pediatr. 2021 May 01;175(5):483-493. doi: 10.1001/jamapediatrics.2020.6087.

IMPORTANCE: The etiologic complexities of preterm birth remain inadequately understood, which may impede the development of better preventative and treatment measures.OBJECTIVE: To examine the association between specific preterm-birth phenotypes and clinical, growth, and neurodevelopmental differences among preterm newborns compared...

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Villar J, Restrepo-Méndez MC, McGready R, et al. Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study. JAMA Pediatr. 2021;175(5):483-493doi: 10.1001/jamapediatrics.2020.6087.
Villar, J., Restrepo-Méndez, M. C., McGready, R., Barros, F. C., Victora, C. G., Munim, S., Papageorghiou, A. T., Ochieng, R., Craik, R., Barsosio, H. C., Berkley, J. A., Carvalho, M., Fernandes, M., Cheikh Ismail, L., Lambert, A., Norris, S. A., Ohuma, E. O., Stein, A., Tshivuila-Matala, C. O. O., Zondervan, K. T., Winsey, A., Nosten, F., Uauy, R., Bhutta, Z. A., & Kennedy, S. H. (2021). Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study. JAMA pediatrics, 175(5), 483-493. https://doi.org/10.1001/jamapediatrics.2020.6087
Villar, Jose, et al. "Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study." JAMA pediatrics vol. 175,5 (2021): 483-493. doi: https://doi.org/10.1001/jamapediatrics.2020.6087
Villar J, Restrepo-Méndez MC, McGready R, Barros FC, Victora CG, Munim S, Papageorghiou AT, Ochieng R, Craik R, Barsosio HC, Berkley JA, Carvalho M, Fernandes M, Cheikh Ismail L, Lambert A, Norris SA, Ohuma EO, Stein A, Tshivuila-Matala COO, Zondervan KT, Winsey A, Nosten F, Uauy R, Bhutta ZA, Kennedy SH. Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study. JAMA Pediatr. 2021 May 01;175(5):483-493. doi: 10.1001/jamapediatrics.2020.6087. PMID: 33646288; PMCID: PMC7922239.
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Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes.

Diabetes

Tong X, Stein R.
PMID: 34433630
Diabetes. 2021 Nov;70(11):2595-2607. doi: 10.2337/db21-0261. Epub 2021 Aug 25.

Free fatty acids (FFAs) are often stored in lipid droplet (LD) depots for eventual metabolic and/or synthetic use in many cell types, such a muscle, liver, and fat. In pancreatic islets, overt LD accumulation was detected in humans but...

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Tong X, Stein R. Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes. Diabetes. 2021;70(11):2595-2607doi: 10.2337/db21-0261.
Tong, X., & Stein, R. (2021). Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes. Diabetes, 70(11), 2595-2607. https://doi.org/10.2337/db21-0261
Tong, Xin, and Stein, Roland. "Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes." Diabetes vol. 70,11 (2021): 2595-2607. doi: https://doi.org/10.2337/db21-0261
Tong X, Stein R. Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes. Diabetes. 2021 Nov;70(11):2595-2607. doi: 10.2337/db21-0261. Epub 2021 Aug 25. PMID: 34433630; PMCID: PMC8564404.
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A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial.

JAMA pediatrics

O'Farrelly C, Watt H, Babalis D, Bakermans-Kranenburg MJ, Barker B, Byford S, Ganguli P, Grimas E, Iles J, Mattock H, McGinley J, Phillips C, Ryan R, Scott S, Smith J, Stein A, Stevens E, van IJzendoorn MH, Warwick J, Ramchandani PG.
PMID: 33720329
JAMA Pediatr. 2021 Jun 01;175(6):567-576. doi: 10.1001/jamapediatrics.2020.6834.

IMPORTANCE: Behavior problems are one of the most common mental health disorders in childhood and can undermine children's health, education, and employment outcomes into adulthood. There are few effective interventions for early childhood.OBJECTIVE: To test the clinical effectiveness of...

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O'Farrelly C, Watt H, Babalis D, et al. A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial. JAMA Pediatr. 2021;175(6):567-576doi: 10.1001/jamapediatrics.2020.6834.
O'Farrelly, C., Watt, H., Babalis, D., Bakermans-Kranenburg, M. J., Barker, B., Byford, S., Ganguli, P., Grimas, E., Iles, J., Mattock, H., McGinley, J., Phillips, C., Ryan, R., Scott, S., Smith, J., Stein, A., Stevens, E., van IJzendoorn, M. H., Warwick, J., & Ramchandani, P. G. (2021). A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial. JAMA pediatrics, 175(6), 567-576. https://doi.org/10.1001/jamapediatrics.2020.6834
O'Farrelly, Christine, et al. "A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial." JAMA pediatrics vol. 175,6 (2021): 567-576. doi: https://doi.org/10.1001/jamapediatrics.2020.6834
O'Farrelly C, Watt H, Babalis D, Bakermans-Kranenburg MJ, Barker B, Byford S, Ganguli P, Grimas E, Iles J, Mattock H, McGinley J, Phillips C, Ryan R, Scott S, Smith J, Stein A, Stevens E, van IJzendoorn MH, Warwick J, Ramchandani PG. A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial. JAMA Pediatr. 2021 Jun 01;175(6):567-576. doi: 10.1001/jamapediatrics.2020.6834. PMID: 33720329; PMCID: PMC7961467.
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Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders.

Laryngoscope investigative otolaryngology

Pai K, Desai H, Stein D, Cole S.
PMID: 34401515
Laryngoscope Investig Otolaryngol. 2021 Jun 10;6(4):872-877. doi: 10.1002/lio2.589. eCollection 2021 Aug.

OBJECTIVE: Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post-tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB. We hypothesize that our medical management...

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Pai K, Desai H, Stein D, et al. Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders. Laryngoscope Investig Otolaryngol. 2021;6(4):872-877doi: 10.1002/lio2.589.
Pai, K., Desai, H., Stein, D., & Cole, S. (2021). Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders. Laryngoscope investigative otolaryngology, 6(4), 872-877. https://doi.org/10.1002/lio2.589
Pai, Kavya, et al. "Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders." Laryngoscope investigative otolaryngology vol. 6,4 (2021): 872-877. doi: https://doi.org/10.1002/lio2.589
Pai K, Desai H, Stein D, Cole S. Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders. Laryngoscope Investig Otolaryngol. 2021 Jun 10;6(4):872-877. doi: 10.1002/lio2.589. eCollection 2021 Aug. PMID: 34401515; PMCID: PMC8356851.
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Showing 1897 to 1901 of 1901 entries