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Showing 5617 to 5626 of 5626 entries
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Phosphate Balance and CKD-Mineral Bone Disease.

Kidney international reports

Sprague SM, Martin KJ, Coyne DW.
PMID: 34386654
Kidney Int Rep. 2021 May 17;6(8):2049-2058. doi: 10.1016/j.ekir.2021.05.012. eCollection 2021 Aug.

Chronic kidney disease-mineral bone disorder (CKD-MBD) is a common comorbidity in patients with CKD. Characterized by laboratory abnormalities, bone abnormality, and vascular calcification, CKD-MBD encompasses a group of mineral and hormone disturbances that are strongly associated with increased cardiovascular...

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Sprague SM, Martin KJ, Coyne DW. Phosphate Balance and CKD-Mineral Bone Disease. Kidney Int Rep. 2021;6(8):2049-2058doi: 10.1016/j.ekir.2021.05.012.
Sprague, S. M., Martin, K. J., & Coyne, D. W. (2021). Phosphate Balance and CKD-Mineral Bone Disease. Kidney international reports, 6(8), 2049-2058. https://doi.org/10.1016/j.ekir.2021.05.012
Sprague, Stuart M, et al. "Phosphate Balance and CKD-Mineral Bone Disease." Kidney international reports vol. 6,8 (2021): 2049-2058. doi: https://doi.org/10.1016/j.ekir.2021.05.012
Sprague SM, Martin KJ, Coyne DW. Phosphate Balance and CKD-Mineral Bone Disease. Kidney Int Rep. 2021 May 17;6(8):2049-2058. doi: 10.1016/j.ekir.2021.05.012. eCollection 2021 Aug. PMID: 34386654; PMCID: PMC8343779.
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Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography.

Journal of structural biology

Morse PE, Stock MK, James KC, Natanson LJ, Stock SR.
PMID: 34999244
J Struct Biol. 2022 Jan 06;214(1):107831. doi: 10.1016/j.jsb.2022.107831. Epub 2022 Jan 06.

Centra of shark vertebrae from three species of Lamniformes (Alopias vulpinus, Carcharodon carcharias and Isurus oxyrinchus) and three species of Carcharhiniformes (Carcharhinus plumbeus, Carcharhinus obscurus and Prionace glauca) were imaged with laboratory microcomputed Tomography (microCT) using volume element (voxel)...

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Morse PE, Stock MK, James KC, et al. Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography. J Struct Biol. 2022;214(1):107831doi: 10.1016/j.jsb.2022.107831.
Morse, P. E., Stock, M. K., James, K. C., Natanson, L. J., & Stock, S. R. (2022). Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography. Journal of structural biology, 214(1), 107831. https://doi.org/10.1016/j.jsb.2022.107831
Morse, Paul E, et al. "Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography." Journal of structural biology vol. 214,1 (2022): 107831. doi: https://doi.org/10.1016/j.jsb.2022.107831
Morse PE, Stock MK, James KC, Natanson LJ, Stock SR. Shark centra microanatomy and mineral density variation studied with laboratory microComputed Tomography. J Struct Biol. 2022 Jan 06;214(1):107831. doi: 10.1016/j.jsb.2022.107831. Epub 2022 Jan 06. PMID: 34999244.
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Liver disease severity predicts carcinogenesis of dysplastic liver nodules in cirrhosis.

Scientific reports

Gazelakis K, Majeed A, Kemp W, Di Muzio B, Gerstenmaier J, Cheung W, Roberts SK.
PMID: 34697374
Sci Rep. 2021 Oct 25;11(1):20954. doi: 10.1038/s41598-021-00474-5.

While dysplastic liver nodules in cirrhosis are pre-malignant, little is known about the predictors of hepatocarcinogenesis of these lesions. This was a retrospective observational study of subjects with cirrhosis who had at least one hypervascular, non-malignant intrahepatic nodule on...

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Gazelakis K, Majeed A, Kemp W, et al. Liver disease severity predicts carcinogenesis of dysplastic liver nodules in cirrhosis. Sci Rep. 2021;11(1):20954doi: 10.1038/s41598-021-00474-5.
Gazelakis, K., Majeed, A., Kemp, W., Di Muzio, B., Gerstenmaier, J., Cheung, W., & Roberts, S. K. (2021). Liver disease severity predicts carcinogenesis of dysplastic liver nodules in cirrhosis. Scientific reports, 11(1), 20954. https://doi.org/10.1038/s41598-021-00474-5
Gazelakis, Kathryn, et al. "Liver disease severity predicts carcinogenesis of dysplastic liver nodules in cirrhosis." Scientific reports vol. 11,1 (2021): 20954. doi: https://doi.org/10.1038/s41598-021-00474-5
Gazelakis K, Majeed A, Kemp W, Di Muzio B, Gerstenmaier J, Cheung W, Roberts SK. Liver disease severity predicts carcinogenesis of dysplastic liver nodules in cirrhosis. Sci Rep. 2021 Oct 25;11(1):20954. doi: 10.1038/s41598-021-00474-5. PMID: 34697374; PMCID: PMC8545953.
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Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter.

Multiple sclerosis (Houndmills, Basingstoke, England)

Klistorner S, Barnett MH, Yiannikas C, Barton J, Parratt J, You Y, Graham SL, Klistorner A.
PMID: 34378454
Mult Scler. 2021 Aug 11;13524585211033464. doi: 10.1177/13524585211033464. Epub 2021 Aug 11.

BACKGROUND: Expansion of chronic multiple sclerosis (MS) lesion is associated with slow-burning inflammation at lesion rim. However, the underlying mechanisms leading to expansion are not fully understood.OBJECTIVE: To investigate the relationship between diffusivity markers of demyelination and axonal loss...

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Klistorner S, Barnett MH, Yiannikas C, et al. Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter. Mult Scler. 2021;13524585211033464doi: 10.1177/13524585211033464.
Klistorner, S., Barnett, M. H., Yiannikas, C., Barton, J., Parratt, J., You, Y., Graham, S. L., & Klistorner, A. (2021). Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter. Multiple sclerosis (Houndmills, Basingstoke, England), 13524585211033464. https://doi.org/10.1177/13524585211033464
Klistorner, Samuel, et al. "Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter." Multiple sclerosis (Houndmills, Basingstoke, England) vol. (2021): 13524585211033464. doi: https://doi.org/10.1177/13524585211033464
Klistorner S, Barnett MH, Yiannikas C, Barton J, Parratt J, You Y, Graham SL, Klistorner A. Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter. Mult Scler. 2021 Aug 11;13524585211033464. doi: 10.1177/13524585211033464. Epub 2021 Aug 11. PMID: 34378454.
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Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research.

Critical care explorations

Verhoef PA, Kannan S, Sturgill JL, Tucker EW, Morris PE, Miller AC, Sexton TR, Koyner JL, Hejal R, Brakenridge SC, Moldawer LL, Hotchkiss RS, Blood TM, Mazer MB, Bolesta S, Alexander SA, Armaignac DL, Shein SL, Jones C, Hoemann CD, Doctor A, Friess SH, Parker RI, Rotta AT, Remy KE.
PMID: 33786450
Crit Care Explor. 2021 Mar 12;3(3):e0374. doi: 10.1097/CCE.0000000000000374. eCollection 2021 Mar.

OBJECTIVES: Since the beginning of the coronavirus disease 2019 pandemic, hundreds of thousands of patients have been treated in ICUs across the globe. The severe acute respiratory syndrome-associated coronavirus 2 virus enters cells via the angiotensin-converting enzyme 2 receptor...

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Verhoef PA, Kannan S, Sturgill JL, et al. Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research. Crit Care Explor. 2021;3(3):e0374doi: 10.1097/CCE.0000000000000374.
Verhoef, P. A., Kannan, S., Sturgill, J. L., Tucker, E. W., Morris, P. E., Miller, A. C., Sexton, T. R., Koyner, J. L., Hejal, R., Brakenridge, S. C., Moldawer, L. L., Hotchkiss, R. S., Blood, T. M., Mazer, M. B., Bolesta, S., Alexander, S. A., Armaignac, D. L., Shein, S. L., Jones, C., Hoemann, C. D., Doctor, A., Friess, S. H., Parker, R. I., Rotta, A. T., & Remy, K. E. (2021). Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research. Critical care explorations, 3(3), e0374. https://doi.org/10.1097/CCE.0000000000000374
Verhoef, Philip A, et al. "Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research." Critical care explorations vol. 3,3 (2021): e0374. doi: https://doi.org/10.1097/CCE.0000000000000374
Verhoef PA, Kannan S, Sturgill JL, Tucker EW, Morris PE, Miller AC, Sexton TR, Koyner JL, Hejal R, Brakenridge SC, Moldawer LL, Hotchkiss RS, Blood TM, Mazer MB, Bolesta S, Alexander SA, Armaignac DL, Shein SL, Jones C, Hoemann CD, Doctor A, Friess SH, Parker RI, Rotta AT, Remy KE. Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research. Crit Care Explor. 2021 Mar 12;3(3):e0374. doi: 10.1097/CCE.0000000000000374. eCollection 2021 Mar. PMID: 33786450; PMCID: PMC7994036.
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The Effect of Amoxicillin in Adult Patients Presenting to Primary Care with Acute Cough Predicted to Have Pneumonia or a Combined Viral-Bacterial Infection.

Antibiotics (Basel, Switzerland)

Bruyndonckx R, Stuart B, Little P, Hens N, Ieven M, Butler CC, Verheij TJM, Goossens H, Coenen S, The Grace Project Group.
PMID: 34356738
Antibiotics (Basel). 2021 Jul 06;10(7). doi: 10.3390/antibiotics10070817.

While most cases of acute cough are self-limiting, antibiotics are prescribed to over 50%. This proportion is inappropriately high given that benefit from treatment with amoxicillin could only be demonstrated in adults with pneumonia (based on chest radiograph) or...

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Bruyndonckx R, Stuart B, Little P, et al. The Effect of Amoxicillin in Adult Patients Presenting to Primary Care with Acute Cough Predicted to Have Pneumonia or a Combined Viral-Bacterial Infection. Antibiotics (Basel). 2021;10(7)doi: 10.3390/antibiotics10070817.
Bruyndonckx, R., Stuart, B., Little, P., Hens, N., Ieven, M., Butler, C. C., Verheij, T. J. M., Goossens, H., Coenen, S., & The Grace Project Group. (2021). The Effect of Amoxicillin in Adult Patients Presenting to Primary Care with Acute Cough Predicted to Have Pneumonia or a Combined Viral-Bacterial Infection. Antibiotics (Basel, Switzerland), 10(7), . https://doi.org/10.3390/antibiotics10070817
Bruyndonckx, Robin, et al. "The Effect of Amoxicillin in Adult Patients Presenting to Primary Care with Acute Cough Predicted to Have Pneumonia or a Combined Viral-Bacterial Infection." Antibiotics (Basel, Switzerland) vol. 10,7 (2021). doi: https://doi.org/10.3390/antibiotics10070817
Bruyndonckx R, Stuart B, Little P, Hens N, Ieven M, Butler CC, Verheij TJM, Goossens H, Coenen S, The Grace Project Group. The Effect of Amoxicillin in Adult Patients Presenting to Primary Care with Acute Cough Predicted to Have Pneumonia or a Combined Viral-Bacterial Infection. Antibiotics (Basel). 2021 Jul 06;10(7). doi: 10.3390/antibiotics10070817. PMID: 34356738; PMCID: PMC8300796.
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Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.

Nature chemistry

Brem J, Panduwawala T, Hansen JU, Hewitt J, Liepins E, Donets P, Espina L, Farley AJM, Shubin K, Campillos GG, Kiuru P, Shishodia S, Krahn D, Leśniak RK, Schmidt Adrian J, Calvopiña K, Turrientes MC, Kavanagh ME, Lubriks D, Hinchliffe P, Langley GW, Aboklaish AF, Eneroth A, Backlund M, Baran AG, Nielsen EI, Speake M, Kuka J, Robinson J, Grinberga S, Robinson L, McDonough MA, Rydzik AM, Leissing TM, Jimenez-Castellanos JC, Avison MB, Da Silva Pinto S, Pannifer AD, Martjuga M, Widlake E, Priede M, Hopkins Navratilova I, Gniadkowski M, Belfrage AK, Brandt P, Yli-Kauhaluoma J, Bacque E, Page MGP, Björkling F, Tyrrell JM, Spencer J, Lang PA, Baranczewski P, Cantón R, McElroy SP, Jones PS, Baquero F, Suna E, Morrison A, Walsh TR, Schofield CJ.
PMID: 34903857
Nat Chem. 2021 Dec 13; doi: 10.1038/s41557-021-00831-x. Epub 2021 Dec 13.

Carbapenems are vital antibiotics, but their efficacy is increasingly compromised by metallo-β-lactamases (MBLs). Here we report the discovery and optimization of potent broad-spectrum MBL inhibitors. A high-throughput screen for NDM-1 inhibitors identified indole-2-carboxylates (InCs) as potential β-lactamase stable β-lactam...

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Brem J, Panduwawala T, Hansen JU, et al. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nat Chem. 2021;doi: 10.1038/s41557-021-00831-x.
Brem, J., Panduwawala, T., Hansen, J. U., Hewitt, J., Liepins, E., Donets, P., Espina, L., Farley, A. J. M., Shubin, K., Campillos, G. G., Kiuru, P., Shishodia, S., Krahn, D., Leśniak, R. K., Schmidt Adrian, J., Calvopiña, K., Turrientes, M. C., Kavanagh, M. E., Lubriks, D., Hinchliffe, P., Langley, G. W., Aboklaish, A. F., Eneroth, A., Backlund, M., Baran, A. G., Nielsen, E. I., Speake, M., Kuka, J., Robinson, J., Grinberga, S., Robinson, L., McDonough, M. A., Rydzik, A. M., Leissing, T. M., Jimenez-Castellanos, J. C., Avison, M. B., Da Silva Pinto, S., Pannifer, A. D., Martjuga, M., Widlake, E., Priede, M., Hopkins Navratilova, I., Gniadkowski, M., Belfrage, A. K., Brandt, P., Yli-Kauhaluoma, J., Bacque, E., Page, M. G. P., Björkling, F., Tyrrell, J. M., Spencer, J., Lang, P. A., Baranczewski, P., Cantón, R., McElroy, S. P., Jones, P. S., Baquero, F., Suna, E., Morrison, A., Walsh, T. R., & Schofield, C. J. (2021). Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nature chemistry, . https://doi.org/10.1038/s41557-021-00831-x
Brem, Jürgen, et al. "Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors." Nature chemistry vol. (2021). doi: https://doi.org/10.1038/s41557-021-00831-x
Brem J, Panduwawala T, Hansen JU, Hewitt J, Liepins E, Donets P, Espina L, Farley AJM, Shubin K, Campillos GG, Kiuru P, Shishodia S, Krahn D, Leśniak RK, Schmidt Adrian J, Calvopiña K, Turrientes MC, Kavanagh ME, Lubriks D, Hinchliffe P, Langley GW, Aboklaish AF, Eneroth A, Backlund M, Baran AG, Nielsen EI, Speake M, Kuka J, Robinson J, Grinberga S, Robinson L, McDonough MA, Rydzik AM, Leissing TM, Jimenez-Castellanos JC, Avison MB, Da Silva Pinto S, Pannifer AD, Martjuga M, Widlake E, Priede M, Hopkins Navratilova I, Gniadkowski M, Belfrage AK, Brandt P, Yli-Kauhaluoma J, Bacque E, Page MGP, Björkling F, Tyrrell JM, Spencer J, Lang PA, Baranczewski P, Cantón R, McElroy SP, Jones PS, Baquero F, Suna E, Morrison A, Walsh TR, Schofield CJ. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nat Chem. 2021 Dec 13; doi: 10.1038/s41557-021-00831-x. Epub 2021 Dec 13. PMID: 34903857.
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Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment.

Water research

Nguyen AQ, Nguyen LN, McDonald JA, Nghiem LD, Leusch FDL, Neale PA, Khan SJ.
PMID: 34872028
Water Res. 2021 Nov 16;209:117871. doi: 10.1016/j.watres.2021.117871. Epub 2021 Nov 16.

This study examined the removal and enantio‑specific fate of a suite of eleven chiral 2-arylpropionic acids (2-APAs) during biological wastewater treatment simulated in a laboratory-scale membrane bioreactor (MBR). Using pure (R)- and (S)- enantiomers in the MBR influent, chiral...

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Nguyen AQ, Nguyen LN, McDonald JA, et al. Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment. Water Res. 2021;209:117871doi: 10.1016/j.watres.2021.117871.
Nguyen, A. Q., Nguyen, L. N., McDonald, J. A., Nghiem, L. D., Leusch, F. D. L., Neale, P. A., & Khan, S. J. (2021). Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment. Water research, 209117871. https://doi.org/10.1016/j.watres.2021.117871
Nguyen, Anh Q, et al. "Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment." Water research vol. 209 (2021): 117871. doi: https://doi.org/10.1016/j.watres.2021.117871
Nguyen AQ, Nguyen LN, McDonald JA, Nghiem LD, Leusch FDL, Neale PA, Khan SJ. Chiral inversion of 2-arylpropionoic acid (2-APA) enantiomers during simulated biological wastewater treatment. Water Res. 2021 Nov 16;209:117871. doi: 10.1016/j.watres.2021.117871. Epub 2021 Nov 16. PMID: 34872028.
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Family monetary incentives as a value-based care model for oral hygiene: rationale and design of the BEhavioral EConomics for Oral health iNnovation (BEECON) trial.

Journal of public health dentistry

Ramos-Gomez F, White JS, Lindau HE, Lin TK, Finlayson TL, Liu JX, Gansky SA.
PMID: 33090505
J Public Health Dent. 2020 Oct 08; doi: 10.1111/jphd.12406. Epub 2020 Oct 08.

BACKGROUND: Effective prevention-focused, value-based strategies are needed to improve oral health. Despite evidence that monetary incentives can motivate healthy behavior, well-powered studies have yet to examine incentives for improving children's oral hygiene.AIM: Describe the rationale and design of the...

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Ramos-Gomez F, White JS, Lindau HE, et al. Family monetary incentives as a value-based care model for oral hygiene: rationale and design of the BEhavioral EConomics for Oral health iNnovation (BEECON) trial. J Public Health Dent. 2020;doi: 10.1111/jphd.12406.
Ramos-Gomez, F., White, J. S., Lindau, H. E., Lin, T. K., Finlayson, T. L., Liu, J. X., & Gansky, S. A. (2020). Family monetary incentives as a value-based care model for oral hygiene: rationale and design of the BEhavioral EConomics for Oral health iNnovation (BEECON) trial. Journal of public health dentistry, . https://doi.org/10.1111/jphd.12406
Ramos-Gomez, Francisco, et al. "Family monetary incentives as a value-based care model for oral hygiene: rationale and design of the BEhavioral EConomics for Oral health iNnovation (BEECON) trial." Journal of public health dentistry vol. (2020). doi: https://doi.org/10.1111/jphd.12406
Ramos-Gomez F, White JS, Lindau HE, Lin TK, Finlayson TL, Liu JX, Gansky SA. Family monetary incentives as a value-based care model for oral hygiene: rationale and design of the BEhavioral EConomics for Oral health iNnovation (BEECON) trial. J Public Health Dent. 2020 Oct 08; doi: 10.1111/jphd.12406. Epub 2020 Oct 08. PMID: 33090505; PMCID: PMC8761083.
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The Washington University Medical Scientist Training Program.

Frieden Carl, Sullivan Brian, Kornfeld StuartA, Goldberg DanielE.
UIID-AD: 89
2004;101:491-5.

Washington University's Medical Scientist Training Program (MSTP) is the largest and among the most successful programs in the country for training physician-scientists. Due to the evolution of biomedicine and as a result of recent initiatives at the National Institutes...

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Frieden Carl, Sullivan Brian, Kornfeld StuartA, et al. The Washington University Medical Scientist Training Program. 2004;101:491-5
Frieden, C. a. r. l., Sullivan, B. r. i. a. n., Kornfeld, S. t. u. a. r. t. A., & Goldberg, D. a. n. i. e. l. E. (2004). The Washington University Medical Scientist Training Program. 101491-5.
Frieden, Carl, et al. "The Washington University Medical Scientist Training Program." vol. 101 (2004): 491-5.
Frieden Carl, Sullivan Brian, Kornfeld StuartA, Goldberg DanielE. The Washington University Medical Scientist Training Program. 2004;101:491-5. UIID-AD: 89.
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Showing 5617 to 5626 of 5626 entries