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Showing 781 to 787 of 787 entries
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Ten-year longitudinal investigation of astigmatism: The Yamagata Study (Funagata).

PloS one

Namba H, Sugano A, Murakami T, Utsunomiya H, Sato H, Nishitsuka K, Ishizawa K, Kayama T, Yamashita H.
PMID: 35007309
PLoS One. 2022 Jan 10;17(1):e0261324. doi: 10.1371/journal.pone.0261324. eCollection 2022.

Despite numerous investigations into ocular or corneal astigmatism, the dynamic nature of astigmatism remains poorly understood. To reveal potential associations between age and astigmatism, 264 Japanese participants who underwent systemic and ophthalmological examinations in Funagata Town (Yamagata Prefecture, Japan)...

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Namba H, Sugano A, Murakami T, et al. Ten-year longitudinal investigation of astigmatism: The Yamagata Study (Funagata). PLoS One. 2022;17(1):e0261324doi: 10.1371/journal.pone.0261324.
Namba, H., Sugano, A., Murakami, T., Utsunomiya, H., Sato, H., Nishitsuka, K., Ishizawa, K., Kayama, T., & Yamashita, H. (2022). Ten-year longitudinal investigation of astigmatism: The Yamagata Study (Funagata). PloS one, 17(1), e0261324. https://doi.org/10.1371/journal.pone.0261324
Namba, Hiroyuki, et al. "Ten-year longitudinal investigation of astigmatism: The Yamagata Study (Funagata)." PloS one vol. 17,1 (2022): e0261324. doi: https://doi.org/10.1371/journal.pone.0261324
Namba H, Sugano A, Murakami T, Utsunomiya H, Sato H, Nishitsuka K, Ishizawa K, Kayama T, Yamashita H. Ten-year longitudinal investigation of astigmatism: The Yamagata Study (Funagata). PLoS One. 2022 Jan 10;17(1):e0261324. doi: 10.1371/journal.pone.0261324. eCollection 2022. PMID: 35007309.
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Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing.

JCI insight

Xie Y, He L, Lugano R, Zhang Y, Cao H, He Q, Chao M, Liu B, Cao Q, Wang J, Jiao Y, Hu Y, Han L, Zhang Y, Huang H, Uhrbom L, Betsholtz C, Wang L, Dimberg A, Zhang L.
PMID: 34228647
JCI Insight. 2021 Aug 09;6(15). doi: 10.1172/jci.insight.150861.

Passage of systemically delivered pharmacological agents into the brain is largely blocked by the blood-brain-barrier (BBB), an organotypic specialization of brain endothelial cells (ECs). Tumor vessels in glioblastoma (GBM), the most common malignant brain tumor in humans, are abnormally...

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Xie Y, He L, Lugano R, et al. Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing. JCI Insight. 2021;6(15)doi: 10.1172/jci.insight.150861.
Xie, Y., He, L., Lugano, R., Zhang, Y., Cao, H., He, Q., Chao, M., Liu, B., Cao, Q., Wang, J., Jiao, Y., Hu, Y., Han, L., Zhang, Y., Huang, H., Uhrbom, L., Betsholtz, C., Wang, L., Dimberg, A., & Zhang, L. (2021). Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing. JCI insight, 6(15), . https://doi.org/10.1172/jci.insight.150861
Xie, Yuan, et al. "Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing." JCI insight vol. 6,15 (2021). doi: https://doi.org/10.1172/jci.insight.150861
Xie Y, He L, Lugano R, Zhang Y, Cao H, He Q, Chao M, Liu B, Cao Q, Wang J, Jiao Y, Hu Y, Han L, Zhang Y, Huang H, Uhrbom L, Betsholtz C, Wang L, Dimberg A, Zhang L. Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing. JCI Insight. 2021 Aug 09;6(15). doi: 10.1172/jci.insight.150861. PMID: 34228647; PMCID: PMC8410070.
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Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress.

Molecular genetics and metabolism

Dobrowolski SF, Phua YL, Sudano C, Spridik K, Zinn PO, Wang Y, Bharathi S, Vockley J, Goetzman E.
PMID: 33846068
Mol Genet Metab. 2021 Apr 07; doi: 10.1016/j.ymgme.2021.04.002. Epub 2021 Apr 07.

Classical phenylketonuria (PKU, OMIM 261600) owes to hepatic deficiency of phenylalanine hydroxylase (PAH) that enzymatically converts phenylalanine (Phe) to tyrosine (Tyr). PKU neurologic phenotypes include impaired brain development, decreased myelination, early onset mental retardation, seizures, and late-onset features (neuropsychiatric,...

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Dobrowolski SF, Phua YL, Sudano C, et al. Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress. Mol Genet Metab. 2021;doi: 10.1016/j.ymgme.2021.04.002.
Dobrowolski, S. F., Phua, Y. L., Sudano, C., Spridik, K., Zinn, P. O., Wang, Y., Bharathi, S., Vockley, J., & Goetzman, E. (2021). Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress. Molecular genetics and metabolism, . https://doi.org/10.1016/j.ymgme.2021.04.002
Dobrowolski, Steven F, et al. "Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress." Molecular genetics and metabolism vol. (2021). doi: https://doi.org/10.1016/j.ymgme.2021.04.002
Dobrowolski SF, Phua YL, Sudano C, Spridik K, Zinn PO, Wang Y, Bharathi S, Vockley J, Goetzman E. Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress. Mol Genet Metab. 2021 Apr 07; doi: 10.1016/j.ymgme.2021.04.002. Epub 2021 Apr 07. PMID: 33846068.
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Salt Solubility and Disproportionation - Uses and Limitations of Equations for pH.

Journal of pharmaceutical sciences

Avdeef A, Sugano K.
PMID: 34863819
J Pharm Sci. 2022 Jan;111(1):225-246. doi: 10.1016/j.xphs.2021.11.017. Epub 2021 Dec 01.

A multiphasic mass action equilibrium model was used to study the phase properties near the critical pH ('pH

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Avdeef A, Sugano K. Salt Solubility and Disproportionation - Uses and Limitations of Equations for pH. J Pharm Sci. 2021;111(1):225-246doi: 10.1016/j.xphs.2021.11.017.
Avdeef, A., & Sugano, K. (2022). Salt Solubility and Disproportionation - Uses and Limitations of Equations for pH. Journal of pharmaceutical sciences, 111(1), 225-246. https://doi.org/10.1016/j.xphs.2021.11.017
Avdeef, Alex, and Sugano, Kiyohiko. "Salt Solubility and Disproportionation - Uses and Limitations of Equations for pH." Journal of pharmaceutical sciences vol. 111,1 (2022): 225-246. doi: https://doi.org/10.1016/j.xphs.2021.11.017
Avdeef A, Sugano K. Salt Solubility and Disproportionation - Uses and Limitations of Equations for pH. J Pharm Sci. 2022 Jan;111(1):225-246. doi: 10.1016/j.xphs.2021.11.017. Epub 2021 Dec 01. PMID: 34863819.
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Comparative Effectiveness of Techniques in Targeted Prostate Biopsy.

Cancers

Sugano D, Kaneko M, Yip W, Lebastchi AH, Cacciamani GE, Abreu AL.
PMID: 33810065
Cancers (Basel). 2021 Mar 22;13(6). doi: 10.3390/cancers13061449.

In this review, we evaluated literature regarding different modalities for multiparametric magnetic resonance imaging (mpMRI) and mpMRI-targeted biopsy (TB) for the detection of prostate cancer (PCa). We identified studies evaluating systematic biopsy (SB) and TB in the same patient,...

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Sugano D, Kaneko M, Yip W, et al. Comparative Effectiveness of Techniques in Targeted Prostate Biopsy. Cancers (Basel). 2021;13(6)doi: 10.3390/cancers13061449.
Sugano, D., Kaneko, M., Yip, W., Lebastchi, A. H., Cacciamani, G. E., & Abreu, A. L. (2021). Comparative Effectiveness of Techniques in Targeted Prostate Biopsy. Cancers, 13(6), . https://doi.org/10.3390/cancers13061449
Sugano, Dordaneh, et al. "Comparative Effectiveness of Techniques in Targeted Prostate Biopsy." Cancers vol. 13,6 (2021). doi: https://doi.org/10.3390/cancers13061449
Sugano D, Kaneko M, Yip W, Lebastchi AH, Cacciamani GE, Abreu AL. Comparative Effectiveness of Techniques in Targeted Prostate Biopsy. Cancers (Basel). 2021 Mar 22;13(6). doi: 10.3390/cancers13061449. PMID: 33810065; PMCID: PMC8004898.
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Delineation of the epileptogenic zone by Phase-amplitude coupling in patients with Bottom of Sulcus Dysplasia.

Seizure

Iimura Y, Mitsuhashi T, Suzuki H, Ueda T, Nishioka K, Otsubo H, Sugano H.
PMID: 34837729
Seizure. 2021 Nov 21;94:23-25. doi: 10.1016/j.seizure.2021.11.006. Epub 2021 Nov 21.

PURPOSE: The removal of the bottom of sulcus dysplasia (BOSD) often includes the gyral crown; however, this method has been controversial. We hypothesized that the epileptogenic zone of the BOSD does not include the gyral crown. To reveal the...

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Iimura Y, Mitsuhashi T, Suzuki H, et al. Delineation of the epileptogenic zone by Phase-amplitude coupling in patients with Bottom of Sulcus Dysplasia. Seizure. 2021;94:23-25doi: 10.1016/j.seizure.2021.11.006.
Iimura, Y., Mitsuhashi, T., Suzuki, H., Ueda, T., Nishioka, K., Otsubo, H., & Sugano, H. (2021). Delineation of the epileptogenic zone by Phase-amplitude coupling in patients with Bottom of Sulcus Dysplasia. Seizure, 9423-25. https://doi.org/10.1016/j.seizure.2021.11.006
Iimura, Yasushi, et al. "Delineation of the epileptogenic zone by Phase-amplitude coupling in patients with Bottom of Sulcus Dysplasia." Seizure vol. 94 (2021): 23-25. doi: https://doi.org/10.1016/j.seizure.2021.11.006
Iimura Y, Mitsuhashi T, Suzuki H, Ueda T, Nishioka K, Otsubo H, Sugano H. Delineation of the epileptogenic zone by Phase-amplitude coupling in patients with Bottom of Sulcus Dysplasia. Seizure. 2021 Nov 21;94:23-25. doi: 10.1016/j.seizure.2021.11.006. Epub 2021 Nov 21. PMID: 34837729.
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A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins.

Biochemical pharmacology

Segawa R, Takeda H, Yokoyama T, Ishida M, Miyata C, Saito T, Ishihara R, Nakagita T, Sasano Y, Kanoh N, Iwabuchi Y, Mizuguchi M, Hiratsuka M, Hirasawa N.
PMID: 34757034
Biochem Pharmacol. 2021 Dec;194:114819. doi: 10.1016/j.bcp.2021.114819. Epub 2021 Oct 30.

Although treatments for allergic diseases have improved, side effects and treatment resistance remain as challenges. New therapeutic drugs for allergic diseases are urgently required. Thymic stromal lymphopoietin (TSLP) is a cytokine target for prevention and treatment of allergic diseases....

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Segawa R, Takeda H, Yokoyama T, et al. A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins. Biochem Pharmacol. 2021;194:114819doi: 10.1016/j.bcp.2021.114819.
Segawa, R., Takeda, H., Yokoyama, T., Ishida, M., Miyata, C., Saito, T., Ishihara, R., Nakagita, T., Sasano, Y., Kanoh, N., Iwabuchi, Y., Mizuguchi, M., Hiratsuka, M., & Hirasawa, N. (2021). A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins. Biochemical pharmacology, 194114819. https://doi.org/10.1016/j.bcp.2021.114819
Segawa, Ryosuke, et al. "A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins." Biochemical pharmacology vol. 194 (2021): 114819. doi: https://doi.org/10.1016/j.bcp.2021.114819
Segawa R, Takeda H, Yokoyama T, Ishida M, Miyata C, Saito T, Ishihara R, Nakagita T, Sasano Y, Kanoh N, Iwabuchi Y, Mizuguchi M, Hiratsuka M, Hirasawa N. A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins. Biochem Pharmacol. 2021 Dec;194:114819. doi: 10.1016/j.bcp.2021.114819. Epub 2021 Oct 30. PMID: 34757034.
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Showing 781 to 787 of 787 entries