Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 277 to 277 of 277 entries
Sorted by: Best Match Show Resources per page
Mechanism of action of hepatitis B virus S antigen transport-inhibiting oligonucleotide polymer, STOPS, molecules.

Molecular therapy. Nucleic acids

Kao CC, Nie Y, Ren S, De Costa NTTS, Pandey RK, Hong J, Smith DB, Symons JA, Beigelman L, Blatt LM.
PMID: 35024245
Mol Ther Nucleic Acids. 2021 Dec 11;27:335-348. doi: 10.1016/j.omtn.2021.12.013. eCollection 2022 Mar 08.

A functional cure of chronic hepatitis B requires eliminating the hepatitis B virus (HBV)-encoded surface antigen (HBsAg), which can suppress immune responses. STOPS are phosphorothioated single-stranded oligonucleotides containing novel chemistries that significantly reduce HBsAgs produced by HBV-infected liver cells....

Showing 277 to 277 of 277 entries