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Showing 13 to 24 of 53 entries
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The Hidden Story of Heterogeneous B-raf V600E Mutation Quantitative Protein Expression in Metastatic Melanoma-Association with Clinical Outcome and Tumor Phenotypes.

Cancers

Betancourt LH, Szasz AM, Kuras M, Rodriguez Murillo J, Sugihara Y, Pla I, Horvath Z, Pawłowski K, Rezeli M, Miharada K, Gil J, Eriksson J, Appelqvist R, Miliotis T, Baldetorp B, Ingvar C, Olsson H, Lundgren L, Horvatovich P, Welinder C, Wieslander E, Kwon HJ, Malm J, Nemeth IB, Jönsson G, Fenyö D, Sanchez A, Marko-Varga G.
PMID: 31835364
Cancers (Basel). 2019 Dec 09;11(12). doi: 10.3390/cancers11121981.

In comparison to other human cancer types, malignant melanoma exhibits the greatest amount of heterogeneity. After DNA-based detection of the BRAF V600E mutation in melanoma patients, targeted inhibitor treatment is the current recommendation. This approach, however, does not take...

Phase diagram of the J_{1}-J_{2} frustrated anisotropic antiferromagnet with spin S=1 on the quadratic lattice.

Physical review. E

Balcerzak T, Szałowski K, Bobák A, Žukovič M.
PMID: 30253562
Phys Rev E. 2018 Aug;98(2):022123. doi: 10.1103/PhysRevE.98.022123.

In the paper the phase diagram of J_{1}-J_{2} frustrated antiferromagnet with spin S=1 and single-ion anisotropy is studied on the planar quadratic lattice in the cluster approximation. The Bogolyubov inequality is adopted for the Gibbs energy calculation for the...

Heavy pnictogen chalcohalides: the synthesis, structure and properties of these rediscovered semiconductors.

Chemical communications (Cambridge, England)

Wlaźlak E, Blachecki A, Bisztyga-Szklarz M, Klejna S, Mazur T, Mech K, Pilarczyk K, Przyczyna D, Suchecki M, Zawal P, Szaciłowski K.
PMID: 30280727
Chem Commun (Camb). 2018 Oct 25;54(86):12133-12162. doi: 10.1039/c8cc05149f.

This review focuses on the synthesis, properties and selected applications of heavy pnictogen chalcohalides, i.e. compounds of the MQX stoichiometry, where M = As, Sb, and Bi; Q = O, S, Se, and Te; and X = F, Cl,...

Molecular engineering of logic gate types by module rearrangement in 'Pourbaix Sensors': the effect of excited-state electric fields.

Organic & biomolecular chemistry

Spiteri JC, Denisov SA, Jonusauskas G, Klejna S, Szaciłowski K, McClenaghan ND, Magri DC.
PMID: 29714805
Org Biomol Chem. 2018 Aug 29;16(34):6195-6201. doi: 10.1039/c8ob00485d.

Two types of fluorescent logic gates are accessed from two different arrangements of the same modular components, one as an AND logic gate (1) and the other as a PASS 0 logic gate (2). The logic gates were designed...

Organotitania-Based Nanostructures as a Suitable Platform for the Implementation of Binary, Ternary, and Fuzzy Logic Systems.

Chemphyschem : a European journal of chemical physics and physical chemistry

Blachecki A, Mech-Piskorz J, Gajewska M, Mech K, Pilarczyk K, Szaciłowski K.
PMID: 28449282
Chemphyschem. 2017 Jul 05;18(13):1798-1810. doi: 10.1002/cphc.201700292. Epub 2017 Jun 08.

Titanium dioxide nanocomposites were synthesized in hierarchical architectures through the use of a 1,4-dihydroxyanthraquinone photosensitizer. In the first step, the dye was either incorporated into the TiO

Spontaneous solitons in the thermal equilibrium of a quasi-1D Bose gas.

Physical review letters

Karpiuk T, Deuar P, Bienias P, Witkowska E, Pawłowski K, Gajda M, Rzążewski K, Brewczyk M.
PMID: 23215499
Phys Rev Lett. 2012 Nov 16;109(20):205302. doi: 10.1103/PhysRevLett.109.205302. Epub 2012 Nov 13.

We show that solitons occur generically in the thermal equilibrium state of a weakly interacting elongated Bose gas, without the need for external forcing or perturbations. This reveals a major new quality to the experimentally widespread quasicondensate state, usually...

Light-driven OR and XOR programmable chemical logic gates.

Journal of the American Chemical Society

Szaciłowski K, Macyk W, Stochel G.
PMID: 16594673
J Am Chem Soc. 2006 Apr 12;128(14):4550-1. doi: 10.1021/ja060694x.

Photoelectrodes made of nanocrystalline titanium dioxide modified with various pentacyanoferrates exhibit unique photoelectrochemical properties; photocurrent direction can be switched from anodic to cathodic and vice versa upon changes in photoelectrode potential and incident light wavelength (PhotoElectrochemical Photocurrent Switching, PEPS...

Band misplacement: a rare complication of laparoscopic adjustable gastric banding.

Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques

Szydłowski K, Michalik M, Pawlak M, Bobowicz M, Frask A.
PMID: 23255999
Wideochir Inne Tech Maloinwazyjne. 2012 Mar;7(1):40-4. doi: 10.5114/wiitm.2011.25930. Epub 2011 Nov 27.

INTRODUCTION: Laparoscopic adjustable gastric banding (LAGB) is considered to be a very effective minimally invasive procedure for treating morbidly obese patients. Nevertheless, there are numerous complications that a good surgeon should be aware of. Most of them have been...

A novel predicted ADP-ribosyltransferase-like family conserved in eukaryotic evolution.

PeerJ

Wyżewski Z, Gradowski M, Krysińska M, Dudkiewicz M, Pawłowski K.
PMID: 33854844
PeerJ. 2021 Mar 10;9:e11051. doi: 10.7717/peerj.11051. eCollection 2021.

The presence of many completely uncharacterized proteins, even in well-studied organisms such as humans, seriously hampers full understanding of the functioning of the living cells. ADP-ribosylation is a common post-translational modification of proteins; also nucleic acids and small molecules...

Structural and mechanistic basis for protein glutamylation by the kinase fold.

Molecular cell

Osinski A, Black MH, Pawłowski K, Chen Z, Li Y, Tagliabracci VS.
PMID: 34407442
Mol Cell. 2021 Nov 04;81(21):4527-4539.e8. doi: 10.1016/j.molcel.2021.08.007. Epub 2021 Aug 17.

The kinase domain transfers phosphate from ATP to substrates. However, the Legionella effector SidJ adopts a kinase fold, yet catalyzes calmodulin (CaM)-dependent glutamylation to inactivate the SidE ubiquitin ligases. The structural and mechanistic basis in which the kinase domain...

Spin State Switching in Heptauthrene Nanostructure by Electric Field: Computational Study.

International journal of molecular sciences

Szałowski K.
PMID: 34948161
Int J Mol Sci. 2021 Dec 13;22(24). doi: 10.3390/ijms222413364.

Recent experimental studies proved the presence of the triplet spin state in atomically precise heptauthrene nanostructure of nanographene type (composed of two interconnected triangles with zigzag edge). In the paper, we report the computational study predicting the possibility of...

Ultrasound Supported Galvanostatic Deposition of Zn Coatings Reinforced with Nano-, Submicro-, and Micro-SiC Particles-Weak Acidic Chloride Baths.

Materials (Basel, Switzerland)

Mech K, Marzec M, Szaciłowski K.
PMID: 34199624
Materials (Basel). 2021 Jun 02;14(11). doi: 10.3390/ma14113033.

In this paper, we present results concerning the electrochemical deposition of Zn-SiC composite coatings reinforced with nano-, submicro-, and microparticles. The influence of current density, particle size, and ultrasound on functional parameters which are especially important from a practical...

Showing 13 to 24 of 53 entries