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Showing 25 to 36 of 2285 entries
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Human retinal pigment epithelial cell proliferation by the combined stimulation of hydroquinone and advanced glycation end-products via up-regulation of .

Biochemistry and biophysics reports

Tsujinaka H, Itaya-Hironaka A, Yamauchi A, Sakuramoto-Tsuchida S, Ota H, Takeda M, Fujimura T, Takasawa S, Ogata N.
PMID: 29124153
Biochem Biophys Rep. 2015 May 29;2:123-131. doi: 10.1016/j.bbrep.2015.05.005. eCollection 2015 Jul.

Although recent research showed that advanced glycation endproduct (AGE) and hydroquinone (HQ) are related to the pathogenesis of age-related macular degeneration (AMD), the mechanism how AGE and HQ induce or accelerate AMD remains elusive. In the present study, we...

Multidetector computed tomography to detect ingested press-through packages: utility of multiplanar reconstruction imaging in the emergency department.

Acute medicine & surgery

Takeda M, Yaguchi A, Harada T, Gotoh T, Namiki M.
PMID: 29123722
Acute Med Surg. 2014 Nov 21;2(3):202-206. doi: 10.1002/ams2.93. eCollection 2015 Jul.

CASE: We investigated the usefulness of multidetector computed tomography during examination in the emergency department to detect the location of press-through packages that had been inadvertently swallowed. In three patients, four press-through packages were detected on multi-planar reconstruction of...

Synergistic palladium/copper-catalyzed Csp.

Chemical communications (Cambridge, England)

Takeda M, Yabushita K, Yasuda S, Ohmiya H.
PMID: 29450439
Chem Commun (Camb). 2018 Jun 19;54(50):6776-6779. doi: 10.1039/c8cc01055b.

The first Csp3-Csp2 cross-coupling using aldehydes as latent α-alkoxyalkyl anion equivalents has been achieved. The synergistic palladium/copper-catalyzed reaction of aromatic aldehydes and aryl bromides with a silylboronate afforded the three-component coupling products, silyl-protected benzhydrol derivatives. The reaction pathway involves...

Interleukin-6/STAT pathway is responsible for the induction of gene expression of REG Iα, a new auto-antigen in Sjögren׳s syndrome patients, in salivary duct epithelial cells.

Biochemistry and biophysics reports

Fujimura T, Fujimoto T, Itaya-Hironaka A, Miyaoka T, Yoshimoto K, Yamauchi A, Sakuramoto-Tsuchida S, Kondo S, Takeda M, Tsujinaka H, Azuma M, Tanaka Y, Takasawa S.
PMID: 29124146
Biochem Biophys Rep. 2015 May 30;2:69-74. doi: 10.1016/j.bbrep.2015.05.006. eCollection 2015 Jul.

The regenerating gene,

Double "Open and Shut" Transformation of γ-Carbolines Triggered by Ammonium Salts: One-Pot Synthesis of Multiheterocyclic Compounds.

Organic letters

Abe T, Shimizu H, Takada S, Tanaka T, Yoshikawa M, Yamada K.
PMID: 29488386
Org Lett. 2018 Mar 16;20(6):1589-1592. doi: 10.1021/acs.orglett.8b00332. Epub 2018 Feb 28.

A novel cascade reaction of indole-2,3-epoxide equivalents with γ-carbolines by utilizing a double "open and shut" transformation to access multiheterocyclic compounds containing both isotryptamines and pyrimido[1,6- a]indoles has been developed. This strategy utilizes the in situ formation of a...

WITHDRAWN: Mut Res special section "Protein modifications in DNA repair and cancer".

Mutation research

Takata M.
PMID: 28641889
Mutat Res. 2017 Jun 15; doi: 10.1016/j.mrfmmm.2017.06.003. Epub 2017 Jun 15.

No abstract available.

Essentiality and function of WalK/WalR two-component system: the past, present, and future of research.

Bioscience, biotechnology, and biochemistry

Takada H, Yoshikawa H.
PMID: 29514560
Biosci Biotechnol Biochem. 2018 May;82(5):741-751. doi: 10.1080/09168451.2018.1444466. Epub 2018 Mar 07.

The WalK/WalR two-component system (TCS), originally identified in

Ruptured thoracic aortic aneurysm infected with listeria monocytogenes: a case report and a review of literature.

Open journal of cardiovascular surgery

Masuda S, Takeuchi N, Takada M, Fujita K, Nishibori Y, Maruyama T.
PMID: 25512697
Open J Cardiovasc Surg. 2013 Apr 29;6:1-7. doi: 10.4137/OJCS.S11446. eCollection 2013.

A 75-year-old male with a history of alcoholic liver cirrhosis, sigmoid colon cancer, and metastatic liver cancer was admitted to our institution with a complaint of a prickly feeling in his chest. On admission, a chest radiograph revealed a...

Effect of oleic Acid vesicles on intestinal absorption of carboxyfluorescein in rats.

Pharmaceutical research

Murakami M, Yoshikawa H, Takada K, Muranishi S.
PMID: 24271354
Pharm Res. 1986 Feb;3(1):35-40. doi: 10.1023/A:1016368714631.

The effect of oleic acid vesicles (ufasomes) on the intestinal absorption of entrapped carboxyfluo-rescein (CF) was investigated by an in situ closed-loop method in rats. Entrapment of CF in ufasomes enhanced the absorption of CF at the earlier stage...

Enhanced selective lymphatic delivery of cyclosporin a by solubilizers and intensified immunosuppressive activity against mice skin allograft.

Pharmaceutical research

Takada K, Yoshimura H, Yoshikawa H, Muranishi S, Yasumura T, Oka T.
PMID: 24271357
Pharm Res. 1986 Feb;3(1):48-51. doi: 10.1023/A:1016324932378.

The absorption and lymphatic delivery of a new immunosuppressive drug, cyclosporin A (CsA), were studied in rats by administering CsA orally after solubilization with HCO-60 (polyoxyethylated hydrogenated castor oil), sugar ester, and oils. After the administration of solubilized CsA...

Highly enhanced thermal stability of Zn4Sb3 nanocomposites.

Chemical communications (Cambridge, England)

Yin H, Johnsen S, Borup KA, Kato K, Takata M, Iversen BB.
PMID: 23764694
Chem Commun (Camb). 2013 Jul 25;49(58):6540-2. doi: 10.1039/c3cc42340a. Epub 2013 Jun 13.

The effects of nano-sized TiO2 and ZnO ceramic inclusions on the high temperature stability of Zn4Sb3 have been studied using multi-temperature synchrotron powder X-ray diffraction. Samples with 9 nm TiO2 nanoinclusions exhibit remarkable stability after three heating cycles to...

Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer.

Case reports in oncology

Hashimoto A, Takada K, Horiguchi H, Sato T, Iyama S, Murase K, Kamihara Y, Ono K, Tatekoshi A, Hayashi T, Miyanishi K, Sato Y, Furuhata T, Kobune M, Takimoto R, Hirata K, Kato J.
PMID: 24932174
Case Rep Oncol. 2014 May 17;7(2):316-22. doi: 10.1159/000363100. eCollection 2014 May.

Therapy-related leukemia (TRL) has been reported to occur after treatment with alkylating agents and/or topoisomerase II inhibitors. Oxaliplatin (OXP) is used as a key drug for the treatment of colorectal cancer (CRC). Cisplatin and carboplatin have been linked with...

Showing 25 to 36 of 2285 entries