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Showing 949 to 956 of 956 entries
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Riluzole Augmentation in Posttraumatic Stress Disorder: Differential Treatment Effect in a High Hyperarousal Subtype.

Journal of clinical psychopharmacology

West JC, Spangler PT, Dempsey CL, Straud CL, Graham K, Thiel F, Benedek DM.
PMID: 33938519
J Clin Psychopharmacol. 2021 Jul-Aug 01;41(4):503-506. doi: 10.1097/JCP.0000000000001406.

No abstract available.

Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein.

Frontiers in immunology

Urban A, Kowalska D, Stasiłojć G, Kuźniewska A, Skrobińska A, Arjona E, Alonso EC, Fenollosa Segarra MÁ, Jongerius I, Spaapen R, Satchell S, Thiel M, Ołdziej S, Rodriguez de Córdoba S, Okrój M.
PMID: 34899688
Front Immunol. 2021 Nov 25;12:724361. doi: 10.3389/fimmu.2021.724361. eCollection 2021.

The impairment of the alternative complement pathway contributes to rare kidney diseases such as atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). We recently described an aHUS patient carrying an exceptional gain-of-function (GoF) mutation (S250C) in the classical...

Clinical Outcome in Patients with Nosocomial COVID-19 Infection After Thoracic Surgery.

Advances in experimental medicine and biology

Al Masri E, Redwan B, Thiel B, Ellger B, Begher C, Biancosino C, Kösek V.
PMID: 34550556
Adv Exp Med Biol. 2021 Sep 23; doi: 10.1007/5584_2021_667. Epub 2021 Sep 23.

In the present study, we retrospectively evaluated outcomes in 8 patients (mean age 67 ± 7, range 55-77 years; male/female 7/1) who acquired nosocomial COVID-19 infection postoperatively out of the 39 adults who underwent elective thoracic surgery in November...

The Long-Term Public Health Impact of a Community-Based Participatory Research Project for Health Promotion Among Socially Disadvantaged Women-A Case Study Protocol.

Frontiers in public health

Abu-Omar K, Ziemainz H, Loss J, Laxy M, Holle R, Thiel A, Herbert-Maul A, Linder S, Till M, Sauter A.
PMID: 33912528
Front Public Health. 2021 Apr 12;9:628630. doi: 10.3389/fpubh.2021.628630. eCollection 2021.

No abstract available.

Structural and functional approaches to studying cAMP regulation of HCN channels.

Biochemical Society transactions

Saponaro A, Thiel G, Moroni A.
PMID: 34812892
Biochem Soc Trans. 2021 Dec 17;49(6):2573-2579. doi: 10.1042/BST20210290.

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are primarily activated by voltage and further modulated by cAMP. While cAMP binding alone does not open the channel, its presence facilitates the action of voltage, increasing channel open probability. Functional results indicate that...

Agricultural fertilization with poultry manure results in persistent environmental contamination with the pathogen Clostridioides difficile.

Environmental microbiology

Frentrup M, Thiel N, Junker V, Behrens W, Münch S, Siller P, Kabelitz T, Faust M, Indra A, Baumgartner S, Schepanski K, Amon T, Roesler U, Funk R, Nübel U.
PMID: 33998128
Environ Microbiol. 2021 May 16; doi: 10.1111/1462-2920.15601. Epub 2021 May 16.

During a field experiment applying broiler manure for fertilization of agricultural land, we detected viable Clostridioides (also known as Clostridium) difficile in broiler faeces, manure, dust and fertilized soil. A large diversity of toxigenic C. difficile isolates was recovered,...

Position of Circulating Tumor Cells in the Clinical Routine in Prostate Cancer and Breast Cancer Patients.

Cancers

Theil G, Fornara P, Bialek J.
PMID: 33333999
Cancers (Basel). 2020 Dec 15;12(12). doi: 10.3390/cancers12123782.

Prostate cancer and breast cancer are the most common cancers worldwide. Anti-tumor therapies are long and exhaustive for the patients. The real-time monitoring of the healing progression could be a useful tool to evaluate therapeutic response. Blood-based biosources like...

BaSAlt - A mixed-methods study protocol on setting-based physical activity promotion and counseling in nursing homes.

Contemporary clinical trials communications

Thiel A, Sudeck G, Niess A, Eschweiler GW, Altmeier D, Haigis D, Pomiersky R, Schmid J, Frahsa A.
PMID: 34401598
Contemp Clin Trials Commun. 2021 Aug 01;23:100828. doi: 10.1016/j.conctc.2021.100828. eCollection 2021 Sep.

INTRODUCTION: Physical activity (PA) is a major contributor to healthy aging. However, physical inactivity is prevalent among the elderly in Germany, particularly in institutionalized settings such as nursing homes. This paper aims to describe the study objectives, design, methods,...

Showing 949 to 956 of 956 entries