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Showing 709 to 719 of 719 entries
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First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [.

Frontiers in endocrinology

Fujimoto H, Fujita N, Hamamatsu K, Murakami T, Nakamoto Y, Saga T, Ishimori T, Shimizu Y, Watanabe H, Sano K, Harada N, Nakamura H, Toyoda K, Kimura H, Nakagawa S, Hirai M, Murakami A, Ono M, Togashi K, Saji H, Inagaki N.
PMID: 34489868
Front Endocrinol (Lausanne). 2021 Aug 19;12:717101. doi: 10.3389/fendo.2021.717101. eCollection 2021.

Pancreatic β-cell mass (BCM) has a central importance in the pathophysiology of diabetes mellitus. Recently, pancreatic β-cell-specific imaging, especially positron emission tomography (PET) with exendin-based probes, has emerged for non-invasive evaluation of BCM. We developed a novel exendin-based probe...

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Fujimoto H, Fujita N, Hamamatsu K, et al. First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [. Front Endocrinol (Lausanne). 2021;12:717101doi: 10.3389/fendo.2021.717101.
Fujimoto, H., Fujita, N., Hamamatsu, K., Murakami, T., Nakamoto, Y., Saga, T., Ishimori, T., Shimizu, Y., Watanabe, H., Sano, K., Harada, N., Nakamura, H., Toyoda, K., Kimura, H., Nakagawa, S., Hirai, M., Murakami, A., Ono, M., Togashi, K., Saji, H., & Inagaki, N. (2021). First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [. Frontiers in endocrinology, 12717101. https://doi.org/10.3389/fendo.2021.717101
Fujimoto, Hiroyuki, et al. "First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [." Frontiers in endocrinology vol. 12 (2021): 717101. doi: https://doi.org/10.3389/fendo.2021.717101
Fujimoto H, Fujita N, Hamamatsu K, Murakami T, Nakamoto Y, Saga T, Ishimori T, Shimizu Y, Watanabe H, Sano K, Harada N, Nakamura H, Toyoda K, Kimura H, Nakagawa S, Hirai M, Murakami A, Ono M, Togashi K, Saji H, Inagaki N. First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [. Front Endocrinol (Lausanne). 2021 Aug 19;12:717101. doi: 10.3389/fendo.2021.717101. eCollection 2021. PMID: 34489868; PMCID: PMC8417326.
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Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids.

mSphere

Hayashi T, Murakami K, Hirano J, Fujii Y, Yamaoka Y, Ohashi H, Watashi K, Estes MK, Muramatsu M.
PMID: 34730374
mSphere. 2021 Dec 22;6(6):e0062321. doi: 10.1128/mSphere.00623-21. Epub 2021 Nov 03.

Human noroviruses (HuNoVs) are acute viral gastroenteritis pathogens that affect all age groups, yet no approved vaccines and drugs to treat HuNoV infection are available. In this study, we screened an antiviral compound library to identify compound(s) showing anti-HuNoV...

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Hayashi T, Murakami K, Hirano J, et al. Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids. mSphere. 2021;6(6):e0062321doi: 10.1128/mSphere.00623-21.
Hayashi, T., Murakami, K., Hirano, J., Fujii, Y., Yamaoka, Y., Ohashi, H., Watashi, K., Estes, M. K., & Muramatsu, M. (2021). Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids. mSphere, 6(6), e0062321. https://doi.org/10.1128/mSphere.00623-21
Hayashi, Tsuyoshi, et al. "Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids." mSphere vol. 6,6 (2021): e0062321. doi: https://doi.org/10.1128/mSphere.00623-21
Hayashi T, Murakami K, Hirano J, Fujii Y, Yamaoka Y, Ohashi H, Watashi K, Estes MK, Muramatsu M. Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids. mSphere. 2021 Dec 22;6(6):e0062321. doi: 10.1128/mSphere.00623-21. Epub 2021 Nov 03. PMID: 34730374; PMCID: PMC8565515.
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Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Higashi H, Yagi H, Kuroda K, Tajima K, Kojima H, Nishi K, Morisaku T, Hirukawa K, Fukuda K, Matsubara K, Kitago M, Shinoda M, Obara H, Adachi S, Nishimura K, Natsume T, Tomi M, Soto-Gutierrez A, Kitagawa Y.
PMID: 34932270
Am J Transplant. 2021 Dec 21; doi: 10.1111/ajt.16928. Epub 2021 Dec 21.

Unlimited organ availability would represent a paradigm shift in transplantation. Long-term in vivo engraftment and function of scaled-up bioengineered liver grafts have not been previously reported. In this study, we describe a human-scale transplantable liver graft engineered on a...

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Higashi H, Yagi H, Kuroda K, et al. Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model. Am J Transplant. 2021;doi: 10.1111/ajt.16928.
Higashi, H., Yagi, H., Kuroda, K., Tajima, K., Kojima, H., Nishi, K., Morisaku, T., Hirukawa, K., Fukuda, K., Matsubara, K., Kitago, M., Shinoda, M., Obara, H., Adachi, S., Nishimura, K., Natsume, T., Tomi, M., Soto-Gutierrez, A., & Kitagawa, Y. (2021). Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, . https://doi.org/10.1111/ajt.16928
Higashi, Hisanobu, et al. "Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons vol. (2021). doi: https://doi.org/10.1111/ajt.16928
Higashi H, Yagi H, Kuroda K, Tajima K, Kojima H, Nishi K, Morisaku T, Hirukawa K, Fukuda K, Matsubara K, Kitago M, Shinoda M, Obara H, Adachi S, Nishimura K, Natsume T, Tomi M, Soto-Gutierrez A, Kitagawa Y. Transplantation of Bioengineered Liver Capable of Extended Function in a Preclinical Liver Failure Model. Am J Transplant. 2021 Dec 21; doi: 10.1111/ajt.16928. Epub 2021 Dec 21. PMID: 34932270.
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Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients.

The Pediatric infectious disease journal

Uehara T, Morino S, Oishi K, Nakamura Y, Togashi N, Imaizumi M, Nishimura S, Okada S, Yara A, Fukushima H, Imagawa K, Takada H.
PMID: 33470775
Pediatr Infect Dis J. 2021 May 01;40(5):460-463. doi: 10.1097/INF.0000000000003060.

BACKGROUND: The antibody response after pneumococcal vaccines and their effectiveness against invasive pneumococcal disease (IPD) in patients with interleukin-1 receptor-associated kinase 4 (IRAK4) deficiency have not been fully evaluated. Here, we evaluated pneumococcal serotype-specific opsonophagocytic activity (OPA) in IRAK4-deficient...

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Uehara T, Morino S, Oishi K, et al. Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients. Pediatr Infect Dis J. 2021;40(5):460-463doi: 10.1097/INF.0000000000003060.
Uehara, T., Morino, S., Oishi, K., Nakamura, Y., Togashi, N., Imaizumi, M., Nishimura, S., Okada, S., Yara, A., Fukushima, H., Imagawa, K., & Takada, H. (2021). Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients. The Pediatric infectious disease journal, 40(5), 460-463. https://doi.org/10.1097/INF.0000000000003060
Uehara, Tomoko, et al. "Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients." The Pediatric infectious disease journal vol. 40,5 (2021): 460-463. doi: https://doi.org/10.1097/INF.0000000000003060
Uehara T, Morino S, Oishi K, Nakamura Y, Togashi N, Imaizumi M, Nishimura S, Okada S, Yara A, Fukushima H, Imagawa K, Takada H. Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients. Pediatr Infect Dis J. 2021 May 01;40(5):460-463. doi: 10.1097/INF.0000000000003060. PMID: 33470775.
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Clinical significance of PET angiography in Takayasu arteritis.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Murao M, Norikane T, Chujo K, Takami Y, Mitamura K, Hanae AO, Yamamoto Y, Maeda Y, Dobashi H, Nishiyama Y.
PMID: 33890186
J Nucl Cardiol. 2021 Apr 22; doi: 10.1007/s12350-021-02619-5. Epub 2021 Apr 22.

No abstract available.

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Murao M, Norikane T, Chujo K, et al. Clinical significance of PET angiography in Takayasu arteritis. J Nucl Cardiol. 2021;doi: 10.1007/s12350-021-02619-5.
Murao, M., Norikane, T., Chujo, K., Takami, Y., Mitamura, K., Hanae, A. O., Yamamoto, Y., Maeda, Y., Dobashi, H., & Nishiyama, Y. (2021). Clinical significance of PET angiography in Takayasu arteritis. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, . https://doi.org/10.1007/s12350-021-02619-5
Murao, Mitsumasa, et al. "Clinical significance of PET angiography in Takayasu arteritis." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. (2021). doi: https://doi.org/10.1007/s12350-021-02619-5
Murao M, Norikane T, Chujo K, Takami Y, Mitamura K, Hanae AO, Yamamoto Y, Maeda Y, Dobashi H, Nishiyama Y. Clinical significance of PET angiography in Takayasu arteritis. J Nucl Cardiol. 2021 Apr 22; doi: 10.1007/s12350-021-02619-5. Epub 2021 Apr 22. PMID: 33890186.
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Glasgow prognostic score for prediction of chemotherapy-triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer.

Thoracic cancer

Kikuchi R, Takoi H, Tsuji T, Nagatomo Y, Tanaka A, Kinoshita H, Ono M, Ishiwari M, Toriyama K, Kono Y, Togashi Y, Yamaguchi K, Yoshimura A, Abe S.
PMID: 33939332
Thorac Cancer. 2021 Jun;12(11):1681-1689. doi: 10.1111/1759-7714.13900. Epub 2021 May 03.

BACKGROUND: Predicting the incidence of chemotherapy-triggered acute exacerbation of interstitial lung disease (AE-ILD) in patients with lung cancer is important because AE-ILD confers a poor prognosis. The Glasgow prognostic score (GPS), which is an inflammation-based index composed of serum...

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Kikuchi R, Takoi H, Tsuji T, et al. Glasgow prognostic score for prediction of chemotherapy-triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer. Thorac Cancer. 2021;12(11):1681-1689doi: 10.1111/1759-7714.13900.
Kikuchi, R., Takoi, H., Tsuji, T., Nagatomo, Y., Tanaka, A., Kinoshita, H., Ono, M., Ishiwari, M., Toriyama, K., Kono, Y., Togashi, Y., Yamaguchi, K., Yoshimura, A., & Abe, S. (2021). Glasgow prognostic score for prediction of chemotherapy-triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer. Thoracic cancer, 12(11), 1681-1689. https://doi.org/10.1111/1759-7714.13900
Kikuchi, Ryota, et al. "Glasgow prognostic score for prediction of chemotherapy-triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer." Thoracic cancer vol. 12,11 (2021): 1681-1689. doi: https://doi.org/10.1111/1759-7714.13900
Kikuchi R, Takoi H, Tsuji T, Nagatomo Y, Tanaka A, Kinoshita H, Ono M, Ishiwari M, Toriyama K, Kono Y, Togashi Y, Yamaguchi K, Yoshimura A, Abe S. Glasgow prognostic score for prediction of chemotherapy-triggered acute exacerbation interstitial lung disease in patients with small cell lung cancer. Thorac Cancer. 2021 Jun;12(11):1681-1689. doi: 10.1111/1759-7714.13900. Epub 2021 May 03. PMID: 33939332; PMCID: PMC8169307.
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Novel chromosomal insertions of ISEcp1-bla.

Antimicrobial resistance and infection control

Shawa M, Furuta Y, Mulenga G, Mubanga M, Mulenga E, Zorigt T, Kaile C, Simbotwe M, Paudel A, Hang'ombe B, Higashi H.
PMID: 33971966
Antimicrob Resist Infect Control. 2021 May 10;10(1):79. doi: 10.1186/s13756-021-00941-8.

BACKGROUND: The epidemiology of extended-spectrum β-lactamases (ESBLs) has undergone dramatic changes, with CTX-M-type enzymes prevailing over other types. blaMETHODS: A total of 46 clinical isolates of cefotaxime-resistant Enterobacteriaceae (1 Enterobacter cloacae, 9 Klebsiella pneumoniae, and 36 Escherichia coli) from...

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Shawa M, Furuta Y, Mulenga G, et al. Novel chromosomal insertions of ISEcp1-bla. Antimicrob Resist Infect Control. 2021;10(1):79doi: 10.1186/s13756-021-00941-8.
Shawa, M., Furuta, Y., Mulenga, G., Mubanga, M., Mulenga, E., Zorigt, T., Kaile, C., Simbotwe, M., Paudel, A., Hang'ombe, B., & Higashi, H. (2021). Novel chromosomal insertions of ISEcp1-bla. Antimicrobial resistance and infection control, 10(1), 79. https://doi.org/10.1186/s13756-021-00941-8
Shawa, Misheck, et al. "Novel chromosomal insertions of ISEcp1-bla." Antimicrobial resistance and infection control vol. 10,1 (2021): 79. doi: https://doi.org/10.1186/s13756-021-00941-8
Shawa M, Furuta Y, Mulenga G, Mubanga M, Mulenga E, Zorigt T, Kaile C, Simbotwe M, Paudel A, Hang'ombe B, Higashi H. Novel chromosomal insertions of ISEcp1-bla. Antimicrob Resist Infect Control. 2021 May 10;10(1):79. doi: 10.1186/s13756-021-00941-8. PMID: 33971966; PMCID: PMC8111917.
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Airway Compromise in Mandibular Fracture.

The Journal of craniofacial surgery

Sasaki R, Togashi C, Miyamoto NS, Okamoto T.
PMID: 34608005
J Craniofac Surg. 2021 Sep 29; doi: 10.1097/SCS.0000000000008219. Epub 2021 Sep 29.

ABSTRACT: Airway compromise is life threatening complication in the maxillofacial fracture. However, the incident of the airway compromise following mandibular fracture was little known. Maxillofacial fractures during the past 3 years from 2017 to 2020 were investigated retrospectively. There...

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Sasaki R, Togashi C, Miyamoto NS, et al. Airway Compromise in Mandibular Fracture. J Craniofac Surg. 2021;doi: 10.1097/SCS.0000000000008219.
Sasaki, R., Togashi, C., Miyamoto, N. S., & Okamoto, T. (2021). Airway Compromise in Mandibular Fracture. The Journal of craniofacial surgery, . https://doi.org/10.1097/SCS.0000000000008219
Sasaki, Ryo, et al. "Airway Compromise in Mandibular Fracture." The Journal of craniofacial surgery vol. (2021). doi: https://doi.org/10.1097/SCS.0000000000008219
Sasaki R, Togashi C, Miyamoto NS, Okamoto T. Airway Compromise in Mandibular Fracture. J Craniofac Surg. 2021 Sep 29; doi: 10.1097/SCS.0000000000008219. Epub 2021 Sep 29. PMID: 34608005.
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A Japanese boy with double diagnoses of 2p15p16.1 microdeletion syndrome and RP2-associated retinal disorder.

Human genome variation

Yamazawa K, Shimizu K, Ohashi H, Haruna H, Inoue S, Murakami H, Matsunaga T, Iwata T, Tsunoda K, Fujinami K.
PMID: 34921139
Hum Genome Var. 2021 Dec 17;8(1):46. doi: 10.1038/s41439-021-00178-2.

2p15p16.1 microdeletion syndrome is a recently recognized congenital disorder characterized by developmental delay and dysmorphic features. RP2-associated retinal disorder (RP2-RD) is an X-linked inherited retinal disease with a childhood onset caused by a loss-of-function variant in the RP2 gene....

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Yamazawa K, Shimizu K, Ohashi H, et al. A Japanese boy with double diagnoses of 2p15p16.1 microdeletion syndrome and RP2-associated retinal disorder. Hum Genome Var. 2021;8(1):46doi: 10.1038/s41439-021-00178-2.
Yamazawa, K., Shimizu, K., Ohashi, H., Haruna, H., Inoue, S., Murakami, H., Matsunaga, T., Iwata, T., Tsunoda, K., & Fujinami, K. (2021). A Japanese boy with double diagnoses of 2p15p16.1 microdeletion syndrome and RP2-associated retinal disorder. Human genome variation, 8(1), 46. https://doi.org/10.1038/s41439-021-00178-2
Yamazawa, Kazuki, et al. "A Japanese boy with double diagnoses of 2p15p16.1 microdeletion syndrome and RP2-associated retinal disorder." Human genome variation vol. 8,1 (2021): 46. doi: https://doi.org/10.1038/s41439-021-00178-2
Yamazawa K, Shimizu K, Ohashi H, Haruna H, Inoue S, Murakami H, Matsunaga T, Iwata T, Tsunoda K, Fujinami K. A Japanese boy with double diagnoses of 2p15p16.1 microdeletion syndrome and RP2-associated retinal disorder. Hum Genome Var. 2021 Dec 17;8(1):46. doi: 10.1038/s41439-021-00178-2. PMID: 34921139; PMCID: PMC8683409.
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Number of fiber bundles in the fetal anterior talofibular ligament.

Surgical and radiologic anatomy : SRA

Edama M, Takabayashi T, Yokota H, Hirabayashi R, Sekine C, Maruyama S, Syagawa M, Togashi R, Yamada Y, Otani H.
PMID: 34379153
Surg Radiol Anat. 2021 Dec;43(12):2077-2081. doi: 10.1007/s00276-021-02816-4. Epub 2021 Aug 11.

PURPOSE: For the anterior talofibular ligament (ATFL), a three-fiber bundle has recently been suggested to be weaker than a single or double fiber bundle in terms of ankle plantarflexion and inversion braking function. However, the studies leading to those...

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Edama M, Takabayashi T, Yokota H, et al. Number of fiber bundles in the fetal anterior talofibular ligament. Surg Radiol Anat. 2021;43(12):2077-2081doi: 10.1007/s00276-021-02816-4.
Edama, M., Takabayashi, T., Yokota, H., Hirabayashi, R., Sekine, C., Maruyama, S., Syagawa, M., Togashi, R., Yamada, Y., & Otani, H. (2021). Number of fiber bundles in the fetal anterior talofibular ligament. Surgical and radiologic anatomy : SRA, 43(12), 2077-2081. https://doi.org/10.1007/s00276-021-02816-4
Edama, Mutsuaki, et al. "Number of fiber bundles in the fetal anterior talofibular ligament." Surgical and radiologic anatomy : SRA vol. 43,12 (2021): 2077-2081. doi: https://doi.org/10.1007/s00276-021-02816-4
Edama M, Takabayashi T, Yokota H, Hirabayashi R, Sekine C, Maruyama S, Syagawa M, Togashi R, Yamada Y, Otani H. Number of fiber bundles in the fetal anterior talofibular ligament. Surg Radiol Anat. 2021 Dec;43(12):2077-2081. doi: 10.1007/s00276-021-02816-4. Epub 2021 Aug 11. PMID: 34379153.
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Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis.

mSystems

Furuta Y, Cheng C, Zorigt T, Paudel A, Izumi S, Tsujinouchi M, Shimizu T, Meijer WG, Higashi H.
PMID: 34282944
mSystems. 2021 Aug 31;6(4):e0029121. doi: 10.1128/mSystems.00291-21. Epub 2021 Jul 20.

AtxA, the master virulence regulator of Bacillus anthracis, regulates the expression of three toxins and genes for capsule formation that are required for the pathogenicity of B. anthracis. Recent transcriptome analyses showed that AtxA affects a large number of...

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Furuta Y, Cheng C, Zorigt T, et al. Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis. mSystems. 2021;6(4):e0029121doi: 10.1128/mSystems.00291-21.
Furuta, Y., Cheng, C., Zorigt, T., Paudel, A., Izumi, S., Tsujinouchi, M., Shimizu, T., Meijer, W. G., & Higashi, H. (2021). Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis. mSystems, 6(4), e0029121. https://doi.org/10.1128/mSystems.00291-21
Furuta, Yoshikazu, et al. "Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis." mSystems vol. 6,4 (2021): e0029121. doi: https://doi.org/10.1128/mSystems.00291-21
Furuta Y, Cheng C, Zorigt T, Paudel A, Izumi S, Tsujinouchi M, Shimizu T, Meijer WG, Higashi H. Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis. mSystems. 2021 Aug 31;6(4):e0029121. doi: 10.1128/mSystems.00291-21. Epub 2021 Jul 20. PMID: 34282944; PMCID: PMC8407390.
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Showing 709 to 719 of 719 entries