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Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms.

Antioxidants (Basel, Switzerland)

Lucarini E, Trallori E, Tomassoni D, Amenta F, Ghelardini C, Pacini A, Di Cesare Mannelli L.
PMID: 32823851
Antioxidants (Basel). 2020 Aug 14;9(8). doi: 10.3390/antiox9080749.

Thioctic acid is a multipotent antioxidant compound existing as dextrorotatory (+), eutomer and naturally occurring and levorotatory (-). It has been proven to help fight many pathologies and is sold as racemate. In agreement with studies claiming a greater...

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Lucarini E, Trallori E, Tomassoni D, et al. Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms. Antioxidants (Basel). 2020;9(8)doi: 10.3390/antiox9080749.
Lucarini, E., Trallori, E., Tomassoni, D., Amenta, F., Ghelardini, C., Pacini, A., & Di Cesare Mannelli, L. (2020). Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms. Antioxidants (Basel, Switzerland), 9(8), . https://doi.org/10.3390/antiox9080749
Lucarini, Elena, et al. "Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms." Antioxidants (Basel, Switzerland) vol. 9,8 (2020). doi: https://doi.org/10.3390/antiox9080749
Lucarini E, Trallori E, Tomassoni D, Amenta F, Ghelardini C, Pacini A, Di Cesare Mannelli L. Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms. Antioxidants (Basel). 2020 Aug 14;9(8). doi: 10.3390/antiox9080749. PMID: 32823851; PMCID: PMC7464875.
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Integrating Exercise Counseling Into the Medical School Curriculum: A Workshop-Based Approach Using Behavior Change Techniques.

American journal of lifestyle medicine

Brennan AM, D'Urzo KA, Fenuta AM, Houlden RL, Tomasone JR.
PMID: 33447173
Am J Lifestyle Med. 2017 Jul 31;15(1):84-107. doi: 10.1177/1559827617722754. eCollection 2021.

No abstract available.

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Brennan AM, D'Urzo KA, Fenuta AM, et al. Integrating Exercise Counseling Into the Medical School Curriculum: A Workshop-Based Approach Using Behavior Change Techniques. Am J Lifestyle Med. 2017;15(1):84-107doi: 10.1177/1559827617722754.
Brennan, A. M., D'Urzo, K. A., Fenuta, A. M., Houlden, R. L., & Tomasone, J. R. (2021). Integrating Exercise Counseling Into the Medical School Curriculum: A Workshop-Based Approach Using Behavior Change Techniques. American journal of lifestyle medicine, 15(1), 84-107. https://doi.org/10.1177/1559827617722754
Brennan, Andrea M, et al. "Integrating Exercise Counseling Into the Medical School Curriculum: A Workshop-Based Approach Using Behavior Change Techniques." American journal of lifestyle medicine vol. 15,1 (2021): 84-107. doi: https://doi.org/10.1177/1559827617722754
Brennan AM, D'Urzo KA, Fenuta AM, Houlden RL, Tomasone JR. Integrating Exercise Counseling Into the Medical School Curriculum: A Workshop-Based Approach Using Behavior Change Techniques. Am J Lifestyle Med. 2017 Jul 31;15(1):84-107. doi: 10.1177/1559827617722754. eCollection 2021. PMID: 33447173; PMCID: PMC7781054.
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[Results of alcoholism treatment 28 months after admission.].

Laeknabladid

Tomasson K.
PMID: 19439799
Laeknabladid. 1999 Sep;85(9):699-706.

OBJECTIVE: Alcoholism and other substance use dis-orders are prevalent chronic disorders. It is therefore important to study the outcome of treatment provided to assess current state as a reference for future comparison.MATERIAL AND METHODS: From December 1991 to September...

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Tomasson K. [Results of alcoholism treatment 28 months after admission.]. Laeknabladid. 1999;85(9):699-706
Tomasson, K. (1999). [Results of alcoholism treatment 28 months after admission.]. Laeknabladid, 85(9), 699-706.
Tomasson, K. "[Results of alcoholism treatment 28 months after admission.]." Laeknabladid vol. 85,9 (1999): 699-706.
Tomasson K. [Results of alcoholism treatment 28 months after admission.]. Laeknabladid. 1999 Sep;85(9):699-706. Icelandic. PMID: 19439799.
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Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review.

ESMO open

Tomasone JR, Brouwers MC, Vukmirovic M, Grunfeld E, O'Brien MA, Urquhart R, Walker M, Webster F, Fitch M.
PMID: 27843639
ESMO Open. 2016 Sep 06;1(5):e000077. doi: 10.1136/esmoopen-2016-000077. eCollection 2016.

Coordination of patient care between primary care and oncology care providers is vital to care quality and outcomes across the cancer continuum, yet it is known to be challenging. We conducted a systematic review to evaluate current or new...

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Tomasone JR, Brouwers MC, Vukmirovic M, et al. Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review. ESMO Open. 2016;1(5):e000077doi: 10.1136/esmoopen-2016-000077.
Tomasone, J. R., Brouwers, M. C., Vukmirovic, M., Grunfeld, E., O'Brien, M. A., Urquhart, R., Walker, M., Webster, F., & Fitch, M. (2016). Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review. ESMO open, 1(5), e000077. https://doi.org/10.1136/esmoopen-2016-000077
Tomasone, Jennifer R, et al. "Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review." ESMO open vol. 1,5 (2016): e000077. doi: https://doi.org/10.1136/esmoopen-2016-000077
Tomasone JR, Brouwers MC, Vukmirovic M, Grunfeld E, O'Brien MA, Urquhart R, Walker M, Webster F, Fitch M. Interventions to improve care coordination between primary healthcare and oncology care providers: a systematic review. ESMO Open. 2016 Sep 06;1(5):e000077. doi: 10.1136/esmoopen-2016-000077. eCollection 2016. PMID: 27843639; PMCID: PMC5070279.
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Antioxidant Properties of Alpha-Lipoic (Thioctic) Acid Treatment on Renal and Heart Parenchyma in a Rat Model of Hypertension.

Antioxidants (Basel, Switzerland)

Martinelli I, Tomassoni D, Roy P, Di Cesare Mannelli L, Amenta F, Tayebati SK.
PMID: 34201726
Antioxidants (Basel). 2021 Jun 23;10(7). doi: 10.3390/antiox10071006.

Renal and cardiac impairments are frequent events in the presence of hypertension. Organ damage is mainly linked to oxidative stress due to high blood pressure and may be reduced by antioxidant supplementation. Alpha-lipoic acid (ALA) is one of most...

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Martinelli I, Tomassoni D, Roy P, et al. Antioxidant Properties of Alpha-Lipoic (Thioctic) Acid Treatment on Renal and Heart Parenchyma in a Rat Model of Hypertension. Antioxidants (Basel). 2021;10(7)doi: 10.3390/antiox10071006.
Martinelli, I., Tomassoni, D., Roy, P., Di Cesare Mannelli, L., Amenta, F., & Tayebati, S. K. (2021). Antioxidant Properties of Alpha-Lipoic (Thioctic) Acid Treatment on Renal and Heart Parenchyma in a Rat Model of Hypertension. Antioxidants (Basel, Switzerland), 10(7), . https://doi.org/10.3390/antiox10071006
Martinelli, Ilenia, et al. "Antioxidant Properties of Alpha-Lipoic (Thioctic) Acid Treatment on Renal and Heart Parenchyma in a Rat Model of Hypertension." Antioxidants (Basel, Switzerland) vol. 10,7 (2021). doi: https://doi.org/10.3390/antiox10071006
Martinelli I, Tomassoni D, Roy P, Di Cesare Mannelli L, Amenta F, Tayebati SK. Antioxidant Properties of Alpha-Lipoic (Thioctic) Acid Treatment on Renal and Heart Parenchyma in a Rat Model of Hypertension. Antioxidants (Basel). 2021 Jun 23;10(7). doi: 10.3390/antiox10071006. PMID: 34201726; PMCID: PMC8300705.
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Primary Results on Safety and Efficacy From the LEADLESS II-Phase 2 Worldwide Clinical Trial.

JACC. Clinical electrophysiology

Reddy VY, Exner DV, Doshi R, Tomassoni G, Bunch TJ, Estes NAM, Neužil P, Paulin FL, Garcia Guerrero JJ, Cantillon DJ.
PMID: 34863657
JACC Clin Electrophysiol. 2021 Nov 12; doi: 10.1016/j.jacep.2021.11.002. Epub 2021 Nov 12.

No abstract available.

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Reddy VY, Exner DV, Doshi R, et al. Primary Results on Safety and Efficacy From the LEADLESS II-Phase 2 Worldwide Clinical Trial. JACC Clin Electrophysiol. 2021;doi: 10.1016/j.jacep.2021.11.002.
Reddy, V. Y., Exner, D. V., Doshi, R., Tomassoni, G., Bunch, T. J., Estes, N. A. M., Neužil, P., Paulin, F. L., Garcia Guerrero, J. J., Cantillon, D. J. (2021). Primary Results on Safety and Efficacy From the LEADLESS II-Phase 2 Worldwide Clinical Trial. JACC. Clinical electrophysiology, . https://doi.org/10.1016/j.jacep.2021.11.002
Reddy, Vivek Y, et al. "Primary Results on Safety and Efficacy From the LEADLESS II-Phase 2 Worldwide Clinical Trial." JACC. Clinical electrophysiology vol. (2021). doi: https://doi.org/10.1016/j.jacep.2021.11.002
Reddy VY, Exner DV, Doshi R, Tomassoni G, Bunch TJ, Estes NAM, Neužil P, Paulin FL, Garcia Guerrero JJ, Cantillon DJ. Primary Results on Safety and Efficacy From the LEADLESS II-Phase 2 Worldwide Clinical Trial. JACC Clin Electrophysiol. 2021 Nov 12; doi: 10.1016/j.jacep.2021.11.002. Epub 2021 Nov 12. PMID: 34863657.
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Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant .

Antibiotics (Basel, Switzerland)

Bonvegna M, Grego E, Sona B, Stella MC, Nebbia P, Mannelli A, Tomassone L.
PMID: 34198805
Antibiotics (Basel). 2021 Jun 05;10(6). doi: 10.3390/antibiotics10060676.

Swine farming as a source of methicillin-resistant

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Bonvegna M, Grego E, Sona B, et al. Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant . Antibiotics (Basel). 2021;10(6)doi: 10.3390/antibiotics10060676.
Bonvegna, M., Grego, E., Sona, B., Stella, M. C., Nebbia, P., Mannelli, A., & Tomassone, L. (2021). Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant . Antibiotics (Basel, Switzerland), 10(6), . https://doi.org/10.3390/antibiotics10060676
Bonvegna, Miryam, et al. "Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant ." Antibiotics (Basel, Switzerland) vol. 10,6 (2021). doi: https://doi.org/10.3390/antibiotics10060676
Bonvegna M, Grego E, Sona B, Stella MC, Nebbia P, Mannelli A, Tomassone L. Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant . Antibiotics (Basel). 2021 Jun 05;10(6). doi: 10.3390/antibiotics10060676. PMID: 34198805; PMCID: PMC8227741.
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Genetically identical twins show comparable tau PET load and spatial distribution.

Brain : a journal of neurology

Coomans EM, Tomassen J, Ossenkoppele R, Golla SSV, den Hollander M, Collij LE, Weltings E, van der Landen S, Wolters EE, Windhorst AD, Barkhof F, de Geus EJC, Scheltens P, Visser PJ, van Berckel BNM, den Braber A.
PMID: 35022652
Brain. 2022 Jan 12; doi: 10.1093/brain/awac004. Epub 2022 Jan 12.

Tau accumulation starts during the preclinical phase of Alzheimer's disease and is closely associated with cognitive decline. For preventive purposes, it is important to identify factors associated with tau accumulation and spread. Studying genetically identical twin-pairs may give insight...

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Coomans EM, Tomassen J, Ossenkoppele R, et al. Genetically identical twins show comparable tau PET load and spatial distribution. Brain. 2022;doi: 10.1093/brain/awac004.
Coomans, E. M., Tomassen, J., Ossenkoppele, R., Golla, S. S. V., den Hollander, M., Collij, L. E., Weltings, E., van der Landen, S., Wolters, E. E., Windhorst, A. D., Barkhof, F., de Geus, E. J. C., Scheltens, P., Visser, P. J., van Berckel, B. N. M., & den Braber, A. (2022). Genetically identical twins show comparable tau PET load and spatial distribution. Brain : a journal of neurology, . https://doi.org/10.1093/brain/awac004
Coomans, Emma M, et al. "Genetically identical twins show comparable tau PET load and spatial distribution." Brain : a journal of neurology vol. (2022). doi: https://doi.org/10.1093/brain/awac004
Coomans EM, Tomassen J, Ossenkoppele R, Golla SSV, den Hollander M, Collij LE, Weltings E, van der Landen S, Wolters EE, Windhorst AD, Barkhof F, de Geus EJC, Scheltens P, Visser PJ, van Berckel BNM, den Braber A. Genetically identical twins show comparable tau PET load and spatial distribution. Brain. 2022 Jan 12; doi: 10.1093/brain/awac004. Epub 2022 Jan 12. PMID: 35022652.
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Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals.

Brain communications

Ingala S, Tomassen J, Collij LE, Prent N, van 't Ent D, Ten Kate M, Konijnenberg E, Yaqub M, Scheltens P, de Geus EJC, Teunissen CE, Tijms B, Wink AM, Barkhof F, van Berckel BNM, Visser PJ, den Braber A.
PMID: 34617016
Brain Commun. 2021 Sep 06;3(4):fcab201. doi: 10.1093/braincomms/fcab201. eCollection 2021.

Cortical accumulation of amyloid beta is one of the first events of Alzheimer's disease pathophysiology, and has been suggested to follow a consistent spatiotemporal ordering, starting in the posterior cingulate cortex, precuneus and medio-orbitofrontal cortex. These regions overlap with...

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Ingala S, Tomassen J, Collij LE, et al. Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals. Brain Commun. 2021;3(4):fcab201doi: 10.1093/braincomms/fcab201.
Ingala, S., Tomassen, J., Collij, L. E., Prent, N., van 't Ent, D., Ten Kate, M., Konijnenberg, E., Yaqub, M., Scheltens, P., de Geus, E. J. C., Teunissen, C. E., Tijms, B., Wink, A. M., Barkhof, F., van Berckel, B. N. M., Visser, P. J., & den Braber, A. (2021). Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals. Brain communications, 3(4), fcab201. https://doi.org/10.1093/braincomms/fcab201
Ingala, Silvia, et al. "Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals." Brain communications vol. 3,4 (2021): fcab201. doi: https://doi.org/10.1093/braincomms/fcab201
Ingala S, Tomassen J, Collij LE, Prent N, van 't Ent D, Ten Kate M, Konijnenberg E, Yaqub M, Scheltens P, de Geus EJC, Teunissen CE, Tijms B, Wink AM, Barkhof F, van Berckel BNM, Visser PJ, den Braber A. Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals. Brain Commun. 2021 Sep 06;3(4):fcab201. doi: 10.1093/braincomms/fcab201. eCollection 2021. PMID: 34617016; PMCID: PMC8490784.
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Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data.

Frontiers in aging neuroscience

Bos I, Vos SJB, Jansen WJ, Vandenberghe R, Gabel S, Estanga A, Ecay-Torres M, Tomassen J, den Braber A, Lleó A, Sala I, Wallin A, Kettunen P, Molinuevo JL, Rami L, Chetelat G, de la Sayette V, Tsolaki M, Freund-Levi Y, Johannsen P, Novak GP, Ramakers I, Verhey FR, Visser PJ.
PMID: 29988624
Front Aging Neurosci. 2018 Jun 25;10:193. doi: 10.3389/fnagi.2018.00193. eCollection 2018.

We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. We included 907 CN individuals from 8 European cohorts...

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Bos I, Vos SJB, Jansen WJ, et al. Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data. Front Aging Neurosci. 2018;10:193doi: 10.3389/fnagi.2018.00193.
Bos, I., Vos, S. J. B., Jansen, W. J., Vandenberghe, R., Gabel, S., Estanga, A., Ecay-Torres, M., Tomassen, J., den Braber, A., Lleó, A., Sala, I., Wallin, A., Kettunen, P., Molinuevo, J. L., Rami, L., Chetelat, G., de la Sayette, V., Tsolaki, M., Freund-Levi, Y., Johannsen, P., Novak, G. P., Ramakers, I., Verhey, F. R., & Visser, P. J. (2018). Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data. Frontiers in aging neuroscience, 10193. https://doi.org/10.3389/fnagi.2018.00193
Bos, Isabelle, et al. "Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data." Frontiers in aging neuroscience vol. 10 (2018): 193. doi: https://doi.org/10.3389/fnagi.2018.00193
Bos I, Vos SJB, Jansen WJ, Vandenberghe R, Gabel S, Estanga A, Ecay-Torres M, Tomassen J, den Braber A, Lleó A, Sala I, Wallin A, Kettunen P, Molinuevo JL, Rami L, Chetelat G, de la Sayette V, Tsolaki M, Freund-Levi Y, Johannsen P, Novak GP, Ramakers I, Verhey FR, Visser PJ. Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data. Front Aging Neurosci. 2018 Jun 25;10:193. doi: 10.3389/fnagi.2018.00193. eCollection 2018. PMID: 29988624; PMCID: PMC6027060.
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Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury.

International journal of molecular sciences

Tomassoni D, Amenta F, Amantini C, Farfariello V, Di Cesare Mannelli L, Nwankwo IE, Marini C, Tayebati SK.
PMID: 23443159
Int J Mol Sci. 2013 Feb 26;14(3):4580-95. doi: 10.3390/ijms14034580.

Oxidative stress is an imbalance between the production of free radicals and antioxidant defense mechanisms, potentially leading to tissue damage. Oxidative stress has a key role in the development of cerebrovascular and/or neurodegenerative diseases. This phenomenon is mainly mediated...

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Tomassoni D, Amenta F, Amantini C, et al. Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury. Int J Mol Sci. 2013;14(3):4580-95doi: 10.3390/ijms14034580.
Tomassoni, D., Amenta, F., Amantini, C., Farfariello, V., Di Cesare Mannelli, L., Nwankwo, I. E., Marini, C., & Tayebati, S. K. (2013). Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury. International journal of molecular sciences, 14(3), 4580-95. https://doi.org/10.3390/ijms14034580
Tomassoni, Daniele, et al. "Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury." International journal of molecular sciences vol. 14,3 (2013): 4580-95. doi: https://doi.org/10.3390/ijms14034580
Tomassoni D, Amenta F, Amantini C, Farfariello V, Di Cesare Mannelli L, Nwankwo IE, Marini C, Tayebati SK. Brain activity of thioctic Acid enantiomers: in vitro and in vivo studies in an animal model of cerebrovascular injury. Int J Mol Sci. 2013 Feb 26;14(3):4580-95. doi: 10.3390/ijms14034580. PMID: 23443159; PMCID: PMC3634420.
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[Carpal tunnel syndrome].

Laeknabladid

Hafstein MP, Bjarnason BA, Tomasson K.
PMID: 21593526
Laeknabladid. 1994 Sep;80(6):300-9.

Analysed are the clinical data of 557 involved hands in 383 patients with carpal tunnel syndrome (CTS) diagnosed and treated in a private neurological practice in Reykjavik, Iceland over a seven year period. The subjects form a selected group...

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Hafstein MP, Bjarnason BA, Tomasson K. [Carpal tunnel syndrome]. Laeknabladid. 1994;80(6):300-9
Hafstein, M. P., Bjarnason, B. A., & Tomasson, K. (1994). [Carpal tunnel syndrome]. Laeknabladid, 80(6), 300-9.
Hafstein, M P, et al. "[Carpal tunnel syndrome]." Laeknabladid vol. 80,6 (1994): 300-9.
Hafstein MP, Bjarnason BA, Tomasson K. [Carpal tunnel syndrome]. Laeknabladid. 1994 Sep;80(6):300-9. Icelandic. PMID: 21593526.
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Showing 25 to 36 of 104 entries