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A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches.

Cancers

Lin CY, Wu RC, Huang CY, Lai CH, Chao AS, Li HP, Tsai CL, Kuek EJ, Hsu CL, Chao A.
PMID: 34885073
Cancers (Basel). 2021 Nov 26;13(23). doi: 10.3390/cancers13235962.

Conventional treatment of dedifferentiated endometrial carcinoma (DEC)-an uncommon and highly aggressive uterine malignancy-is beset by high failure rates. A line of research that holds promise to overcome these limitations is tailored treatments targeted on specific molecular alterations. However, suitable...

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Lin CY, Wu RC, Huang CY, et al. A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches. Cancers (Basel). 2021;13(23)doi: 10.3390/cancers13235962.
Lin, C. Y., Wu, R. C., Huang, C. Y., Lai, C. H., Chao, A. S., Li, H. P., Tsai, C. L., Kuek, E. J., Hsu, C. L., & Chao, A. (2021). A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches. Cancers, 13(23), . https://doi.org/10.3390/cancers13235962
Lin, Chiao-Yun, et al. "A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches." Cancers vol. 13,23 (2021). doi: https://doi.org/10.3390/cancers13235962
Lin CY, Wu RC, Huang CY, Lai CH, Chao AS, Li HP, Tsai CL, Kuek EJ, Hsu CL, Chao A. A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches. Cancers (Basel). 2021 Nov 26;13(23). doi: 10.3390/cancers13235962. PMID: 34885073.
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Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning.

Pharmaceuticals (Basel, Switzerland)

Bicakci AO, Tsai PL, Kahl E, Mayer D, Fendt M.
PMID: 34358069
Pharmaceuticals (Basel). 2021 Jul 05;14(7). doi: 10.3390/ph14070643.

Cognitive flexibility refers to the ability to modify learned behavior in response to changes in the environment. In laboratory rodents, cognitive flexibility can be assessed in reversal learning, i.e., the change of contingencies, for example in T-maze discrimination learning....

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Bicakci AO, Tsai PL, Kahl E, et al. Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel). 2021;14(7)doi: 10.3390/ph14070643.
Bicakci, A. O., Tsai, P. L., Kahl, E., Mayer, D., & Fendt, M. (2021). Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel, Switzerland), 14(7), . https://doi.org/10.3390/ph14070643
Bicakci, Ahmet Oguzhan, et al. "Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning." Pharmaceuticals (Basel, Switzerland) vol. 14,7 (2021). doi: https://doi.org/10.3390/ph14070643
Bicakci AO, Tsai PL, Kahl E, Mayer D, Fendt M. Dissociative Effects of Neuropeptide S Receptor Deficiency and Nasal Neuropeptide S Administration on T-Maze Discrimination and Reversal Learning. Pharmaceuticals (Basel). 2021 Jul 05;14(7). doi: 10.3390/ph14070643. PMID: 34358069; PMCID: PMC8308873.
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Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation.

Neuromodulation : journal of the International Neuromodulation Society

Huang RY, Poree L, Ho KY, Tsai SY, Liu YC, Tan PH, Wen YR.
PMID: 32558126
Neuromodulation. 2021 Dec;24(8):1458-1466. doi: 10.1111/ner.13169. Epub 2020 Jun 17.

OBJECTIVES: Pulsed radiofrequency (PRF) stimulation is widely used for intractable pain; however, there is no consensus on treatment protocols and appropriate types of pain. We compared effectiveness of bipolar and unipolar PRF on neuropathic or inflammatory pains, and of...

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Huang RY, Poree L, Ho KY, et al. Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation. 2020;24(8):1458-1466doi: 10.1111/ner.13169.
Huang, R. Y., Poree, L., Ho, K. Y., Tsai, S. Y., Liu, Y. C., Tan, P. H., & Wen, Y. R. (2021). Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation : journal of the International Neuromodulation Society, 24(8), 1458-1466. https://doi.org/10.1111/ner.13169
Huang, Ren-Yu, et al. "Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation." Neuromodulation : journal of the International Neuromodulation Society vol. 24,8 (2021): 1458-1466. doi: https://doi.org/10.1111/ner.13169
Huang RY, Poree L, Ho KY, Tsai SY, Liu YC, Tan PH, Wen YR. Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation. 2021 Dec;24(8):1458-1466. doi: 10.1111/ner.13169. Epub 2020 Jun 17. PMID: 32558126.
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IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy.

International journal of molecular sciences

Tsai ML, Tsai YG, Lin YC, Hsu YL, Chen YT, Tsai MK, Liao WT, Lin YC, Hung CH.
PMID: 35008429
Int J Mol Sci. 2021 Dec 21;23(1). doi: 10.3390/ijms23010003.

Interleukin (IL)-25 is a cytokine released by airway epithelial cells responding to pathogens. Excessive production of reactive oxygen species (ROS) leads to airway inflammation and remodeling in asthma. Mitochondria are the major source of ROS. After stress, defective mitochondria...

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Tsai ML, Tsai YG, Lin YC, et al. IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy. Int J Mol Sci. 2021;23(1)doi: 10.3390/ijms23010003.
Tsai, M. L., Tsai, Y. G., Lin, Y. C., Hsu, Y. L., Chen, Y. T., Tsai, M. K., Liao, W. T., Lin, Y. C., & Hung, C. H. (2021). IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy. International journal of molecular sciences, 23(1), . https://doi.org/10.3390/ijms23010003
Tsai, Mei-Lan, et al. "IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy." International journal of molecular sciences vol. 23,1 (2021). doi: https://doi.org/10.3390/ijms23010003
Tsai ML, Tsai YG, Lin YC, Hsu YL, Chen YT, Tsai MK, Liao WT, Lin YC, Hung CH. IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy. Int J Mol Sci. 2021 Dec 21;23(1). doi: 10.3390/ijms23010003. PMID: 35008429.
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Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films.

Journal of nanoscience and nanotechnology

Ou SL, Kuo PC, Sheu SC, Shen CL, Tsai TL, Chen SC, Chiang DY.
PMID: 22409026
J Nanosci Nanotechnol. 2011 Dec;11(12):10922-5. doi: 10.1166/jnn.2011.3998.

The (In15Sb85)(100-x)Zn(x) films (x = 0 - 17.4) were deposited on nature oxidized Si wafer and glass substrate at room temperature by magnetron co-sputtering of Sb target and InZn composite target. The thermal property of the films was examined...

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Ou SL, Kuo PC, Sheu SC, et al. Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films. J Nanosci Nanotechnol. 2011;11(12):10922-5doi: 10.1166/jnn.2011.3998.
Ou, S. L., Kuo, P. C., Sheu, S. C., Shen, C. L., Tsai, T. L., Chen, S. C., & Chiang, D. Y. (2011). Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films. Journal of nanoscience and nanotechnology, 11(12), 10922-5. https://doi.org/10.1166/jnn.2011.3998
Ou, S L, et al. "Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films." Journal of nanoscience and nanotechnology vol. 11,12 (2011): 10922-5. doi: https://doi.org/10.1166/jnn.2011.3998
Ou SL, Kuo PC, Sheu SC, Shen CL, Tsai TL, Chen SC, Chiang DY. Microstructure and crystallization kinetics analysis of the (In15Sb85)(100-x)Zn(x) phase change recording thin films. J Nanosci Nanotechnol. 2011 Dec;11(12):10922-5. doi: 10.1166/jnn.2011.3998. PMID: 22409026.
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7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan.

Gastroenterology research and practice

Kao SS, Chen WC, Hsu PI, Lai KH, Yu HC, Cheng HH, Peng NJ, Lin CK, Chan HH, Tsai WL, Wang HM, Tsai TJ, Lin KH, Tsay FW.
PMID: 22888337
Gastroenterol Res Pract. 2012;2012:463985. doi: 10.1155/2012/463985. Epub 2012 Jul 22.

Background. Ten-day concomitant therapy achieves a high eradication rate in Taiwan. Whether shortening the duration of concomitant therapy can still keep a high eradication rate remains unclear. Aim. To assess the eradication rate of 7-day pantoprazole-containing concomitant therapy in...

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Kao SS, Chen WC, Hsu PI, et al. 7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan. Gastroenterol Res Pract. 2012;2012:463985doi: 10.1155/2012/463985.
Kao, S. S., Chen, W. C., Hsu, P. I., Lai, K. H., Yu, H. C., Cheng, H. H., Peng, N. J., Lin, C. K., Chan, H. H., Tsai, W. L., Wang, H. M., Tsai, T. J., Lin, K. H., & Tsay, F. W. (2012). 7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan. Gastroenterology research and practice, 2012463985. https://doi.org/10.1155/2012/463985
Kao, Sung-Shuo, et al. "7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan." Gastroenterology research and practice vol. 2012 (2012): 463985. doi: https://doi.org/10.1155/2012/463985
Kao SS, Chen WC, Hsu PI, Lai KH, Yu HC, Cheng HH, Peng NJ, Lin CK, Chan HH, Tsai WL, Wang HM, Tsai TJ, Lin KH, Tsay FW. 7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan. Gastroenterol Res Pract. 2012;2012:463985. doi: 10.1155/2012/463985. Epub 2012 Jul 22. PMID: 22888337; PMCID: PMC3408719.
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Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq.

Nature protocols

Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ.
PMID: 34773119
Nat Protoc. 2021 Dec;16(12):5592-5615. doi: 10.1038/s41596-021-00626-x. Epub 2021 Nov 12.

Genome-wide unbiased identification of double-stranded breaks enabled by sequencing (GUIDE-seq) is a sensitive, unbiased, genome-wide method for defining the activity of genome-editing nucleases in living cells. GUIDE-seq is based on the principle of efficient integration of an end-protected double-stranded...

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Malinin NL, Lee G, Lazzarotto CR, et al. Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq. Nat Protoc. 2021;16(12):5592-5615doi: 10.1038/s41596-021-00626-x.
Malinin, N. L., Lee, G., Lazzarotto, C. R., Li, Y., Zheng, Z., Nguyen, N. T., Liebers, M., Topkar, V. V., Iafrate, A. J., Le, L. P., Aryee, M. J., Joung, J. K., & Tsai, S. Q. (2021). Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq. Nature protocols, 16(12), 5592-5615. https://doi.org/10.1038/s41596-021-00626-x
Malinin, Nikolay L, et al. "Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq." Nature protocols vol. 16,12 (2021): 5592-5615. doi: https://doi.org/10.1038/s41596-021-00626-x
Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ. Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq. Nat Protoc. 2021 Dec;16(12):5592-5615. doi: 10.1038/s41596-021-00626-x. Epub 2021 Nov 12. PMID: 34773119.
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Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells.

OncoTargets and therapy

Tsai SC, Wu WC, Yang JS.
PMID: 34456573
Onco Targets Ther. 2021 Aug 21;14:4523-4536. doi: 10.2147/OTT.S324552. eCollection 2021.

INTRODUCTION: Patients with colorectal cancer (CRC) often develop distant metastases, which significantly reduces the 5-year survival rate. Epithelial-mesenchymal transition (EMT) is a crucial process for the invasion and metastasis of cancer cells. Tetrandrine has been reported to inhibit the...

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Tsai SC, Wu WC, Yang JS. Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. Onco Targets Ther. 2021;14:4523-4536doi: 10.2147/OTT.S324552.
Tsai, S. C., Wu, W. C., & Yang, J. S. (2021). Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. OncoTargets and therapy, 144523-4536. https://doi.org/10.2147/OTT.S324552
Tsai, Shih-Chang, et al. "Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells." OncoTargets and therapy vol. 14 (2021): 4523-4536. doi: https://doi.org/10.2147/OTT.S324552
Tsai SC, Wu WC, Yang JS. Tetrandrine Inhibits Epithelial-Mesenchymal Transition in IL-6-Induced HCT116 Human Colorectal Cancer Cells. Onco Targets Ther. 2021 Aug 21;14:4523-4536. doi: 10.2147/OTT.S324552. eCollection 2021. PMID: 34456573; PMCID: PMC8387317.
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Sucrose, maltodextrin and inulin efficacy as cryoprotectant, preservative and prebiotic - towards a freeze dried .

Biotechnology reports (Amsterdam, Netherlands)

Oluwatosin SO, Tai SL, Fagan-Endres MA.
PMID: 35024350
Biotechnol Rep (Amst). 2021 Dec 24;33:e00696. doi: 10.1016/j.btre.2021.e00696. eCollection 2022 Mar.

Probiotic formulations must contain the right strain(s) in sufficient numbers when administered to confer the desired health benefit. However, significant cell death can occur during freeze-drying and over storage. This study assesses various saccharides for their ability to protect

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Oluwatosin SO, Tai SL, Fagan-Endres MA. Sucrose, maltodextrin and inulin efficacy as cryoprotectant, preservative and prebiotic - towards a freeze dried . Biotechnol Rep (Amst). 2021;33:e00696doi: 10.1016/j.btre.2021.e00696.
Oluwatosin, S. O., Tai, S. L., & Fagan-Endres, M. A. (2022). Sucrose, maltodextrin and inulin efficacy as cryoprotectant, preservative and prebiotic - towards a freeze dried . Biotechnology reports (Amsterdam, Netherlands), 33e00696. https://doi.org/10.1016/j.btre.2021.e00696
Oluwatosin, Sumbo Oluwatoyin, et al. "Sucrose, maltodextrin and inulin efficacy as cryoprotectant, preservative and prebiotic - towards a freeze dried ." Biotechnology reports (Amsterdam, Netherlands) vol. 33 (2022): e00696. doi: https://doi.org/10.1016/j.btre.2021.e00696
Oluwatosin SO, Tai SL, Fagan-Endres MA. Sucrose, maltodextrin and inulin efficacy as cryoprotectant, preservative and prebiotic - towards a freeze dried . Biotechnol Rep (Amst). 2021 Dec 24;33:e00696. doi: 10.1016/j.btre.2021.e00696. eCollection 2022 Mar. PMID: 35024350; PMCID: PMC8732778.
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Showing 1537 to 1545 of 1545 entries