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Retrospective analysis (2009-2017) of factors associated with progression and regression of non-alcoholic fatty liver disease (Hepatic steatosis) in patients with type 2 diabetes seen at a tertiary diabetes centre in Southern India.

Diabetes & metabolic syndrome

Kamalraj N, Sathishkumar M, Arunvignesh M, Baskar V, Jebarani S, Amutha A, Deepa M, Shanthi Rani CS, Chandru S, Unnikrishnan R, Anjana RM, Harish M, Mohan V.
PMID: 34464909
Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102261. doi: 10.1016/j.dsx.2021.102261. Epub 2021 Aug 25.

AIM: To identify the profiles and factors associated with progression/regression of ultrasound-derived hepatic steatosis with type 2 diabetes mellitus seen at a tertiary diabetes center in southern India.METHODS: Participants were individuals with type 2 diabetes mellitus with at least...

The RNA Atlas expands the catalog of human non-coding RNAs.

Nature biotechnology

Lorenzi L, Chiu HS, Avila Cobos F, Gross S, Volders PJ, Cannoodt R, Nuytens J, Vanderheyden K, Anckaert J, Lefever S, Tay AP, de Bony EJ, Trypsteen W, Gysens F, Vromman M, Goovaerts T, Hansen TB, Kuersten S, Nijs N, Taghon T, Vermaelen K, Bracke KR, Saeys Y, De Meyer T, Deshpande NP, Anande G, Chen TW, Wilkins MR, Unnikrishnan A, De Preter K, Kjems J, Koster J, Schroth GP, Vandesompele J, Sumazin P, Mestdagh P.
PMID: 34140680
Nat Biotechnol. 2021 Nov;39(11):1453-1465. doi: 10.1038/s41587-021-00936-1. Epub 2021 Jun 17.

Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are derived almost exclusively from small and polyadenylated RNAs. Here we present a more comprehensive atlas of the human transcriptome, which includes small and polyA RNA as...

Cerebral Vasculature Influences Blast-Induced Biomechanical Responses of Human Brain Tissue.

Frontiers in bioengineering and biotechnology

Subramaniam DR, Unnikrishnan G, Sundaramurthy A, Rubio JE, Kote VB, Reifman J.
PMID: 34805106
Front Bioeng Biotechnol. 2021 Nov 04;9:744808. doi: 10.3389/fbioe.2021.744808. eCollection 2021.

Multiple finite-element (FE) models to predict the biomechanical responses in the human brain resulting from the interaction with blast waves have established the importance of including the brain-surface convolutions, the major cerebral veins, and using non-linear brain-tissue properties to...

Outcome of the scarf osteotomy in adolescent hallux valgus.

Journal of children's orthopaedics

George HL, Casaletto J, Unnikrishnan PN, Shivratri D, James LA, Bass A, Bruce CE.
PMID: 19421795
J Child Orthop. 2009 Jun;3(3):185-90. doi: 10.1007/s11832-009-0177-6. Epub 2009 May 07.

PURPOSE: We have reported the radiological and clinical outcome of scarf osteotomy in the treatment of moderate to severe hallux valgus among adolescent children.METHOD: Data were collected retrospectively between April 2001 and June 2006. The pre- and post-operative intermetatarsal...

Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant.

Science (New York, N.Y.)

Elliott P, Haw D, Wang H, Eales O, Walters CE, Ainslie KEC, Atchison C, Fronterre C, Diggle PJ, Page AJ, Trotter AJ, Prosolek SJ, Ashby D, Donnelly CA, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Robson SC, Loman NJ, Connor TR, Golubchik T, Martinez Nunez RT, Ludden C, Corden S, Johnston I, Bonsall D, Smith CP, Awan AR, Bucca G, Torok ME, Saeed K, Prieto JA, Jackson DK, Hamilton WL, Snell LB, Moore C, Harrison EM, Goncalves S, Jackson LM, Goodfellow IG, Fairley DJ, Loose MW, Watkins J, Livett R, Moses S, Amato R, Nicholls S, Bull M, Smith DL, Barrett J, Aanensen DM, Curran MD, Parmar S, Aggarwal D, Shepherd JG, Parker MD, Glaysher S, Bashton M, Underwood AP, Pacchiarini N, Loveson KF, Carabelli AM, Templeton KE, Langford CF, Sillitoe J, de Silva TI, Wang D, Kwiatkowski D, Rambaut A, O'Grady J, Cottrell S, Holden MTG, Thomson EC, Osman H, Andersson M, Chauhan AJ, Hassan-Ibrahim MO, Lawniczak M, Gupta RK, Alderton A, Chand M, Constantinidou C, Unnikrishnan M, Darby AC, Hiscox JA, Paterson S, Martincorena I, Robertson DL, Volz EM, Page AJ, Pybus OG, Bassett AR, Ariani CV, Spencer Chapman MH, Li KK, Shah RN, Jesudason NG, Taha Y, McHugh MP, Dewar R, Jahun AS, McMurray C, Pandey S, McKenna JP, Nelson A, Young GR, McCann CM, Elliott S, Lowe H, Temperton B, Roy S, Price A, Rey S, Wyles M, Rooke S, Shaaban S, de Cesare M, Letchford L, Silveira S, Pelosi E, Wilson-Davies E, Hosmillo M, O'Toole Á, Hesketh AR, Stark R, du Plessis L, Ruis C, Adams H, Bourgeois Y, Michell SL, Grammatopoulos D, Edgeworth J, Breuer J, Todd JA, Fraser C, Buck D, John M, Kay GL, Palmer S, Peacock SJ, Heyburn D, Weldon D, Robinson E, McNally A, Muir P, Vipond IB, Boyes J, Sivaprakasam V, Saluja T, Dervisevic S, Meader EJ, Park NR, Oliver K, Jeffries AR, Ott S, da Silva Filipe A, Simpson DA, Williams C, Masoli JA, Knight BA, Jones CR, Koshy C, Ash A, Casey A, Bosworth A, Ratcliffe L, Xu-McCrae L, Pymont HM, Hutchings S, Berry L, Jones K, Halstead F, Davis T, Holmes C, Iturriza-Gomara M, Lucaci AO, Randell PA, Cox A, Madona P, Harris KA, Brown JR, Mahungu TW, Irish-Tavares D, Haque T, Hart J, Witele E, Fenton ML, Liggett S, Graham C, Swindells E, Collins J, Eltringham G, Campbell S, McClure PC, Clark G, Sloan TJ, Jones C, Lynch J, Warne B, Leonard S, Durham J, Williams T, Haldenby ST, Storey N, Alikhan NF, Holmes N, Moore C, Carlile M, Perry M, Craine N, Lyons RA, Beckett AH, Goudarzi S, Fearn C, Cook K, Dent H, Paul H, Davies R, Blane B, Girgis ST, Beale MA, Bellis KL, Dorman MJ, Drury E, Kane L, Kay S, McGuigan S, Nelson R, Prestwood L, Rajatileka S, Batra R, Williams RJ, Kristiansen M, Green A, Justice A, Mahanama AIK, Samaraweera B, Hadjirin NF, Quick J, Poplawski R, Kermack LM, Reynolds N, Hall G, Chaudhry Y, Pinckert ML, Georgana I, Moll RJ, Thornton A, Myers R, Stockton J, Williams CA, Yew WC, Trotter AJ, Trebes A, MacIntyre-Cockett G, Birchley A, Adams A, Plimmer A, Gatica-Wilcox B, McKerr C, Hilvers E, Jones H, Asad H, Coombes J, Evans JM, Fina L, Gilbert L, Graham L, Cronin M, Kumziene-Summerhayes S, Taylor S, Jones S, Groves DC, Zhang P, Gallis M, Louka SF, Starinskij I, Keatley JP, Singer JB, de Oliveira Martins L, Yeats CA, Abudahab K, Taylor BE, Menegazzo M, Danesh J, Hogsden W, Eldirdiri S, Kenyon A, Mason J, Robinson TI, Holmes A, Price J, Hartley JA, Curran T, Mather AE, Shankar G, Jones R, Howe R, Morgan S, Wastenge E, Chapman MR, Mookerjee S, Stanley R, Smith W, Peto T, Eyre D, Crook D, Vernet G, Kitchen C, Gulliver H, Merrick I, Guest M, Munn R, Bradley DT, Wyatt T, Beaver C, Foulser L, Palmer S, Churcher CM, Brooks E, Smith KS, Galai K, McManus GM, Bolt F, Coll F, Meadows L, Attwood SW, Davies A, De Lacy E, Downing F, Edwards S, Scarlett GP, Jeremiah S, Smith N, Leek D, Sridhar S, Forrest S, Cormie C, Gill HK, Dias J, Higginson EE, Maes M, Young J, Wantoch M, Jamrozy D, Lo S, Patel M, Hill V, Bewshea CM, Ellard S, Auckland C, Harrison I, Bishop C, Chalker V, Richter A, Beggs A, Best A, Percival B, Mirza J, Megram O, Mayhew M, Crawford L, Ashcroft F, Moles-Garcia E, Cumley N, Hopes R, Asamaphan P, Niebel MO, Gunson RN, Bradley A, Maclean A, Mollett G, Blacow R, Bird P, Helmer T, Fallon K, Tang J, Hale AD, Macfarlane-Smith LR, Harper KL, Carden H, Machin NW, Jackson KA, Ahmad SSY, George RP, Turtle L, O'Toole E, Watts J, Breen C, Cowell A, Alcolea-Medina A, Charalampous T, Patel A, Levett LJ, Heaney J, Rowan A, Taylor GP, Shah D, Atkinson L, Lee JC, Westhorpe AP, Jannoo R, Lowe HL, Karamani A, Ensell L, Chatterton W, Pusok M, Dadrah A, Symmonds A, Sluga G, Molnar Z, Baker P, Bonner S, Essex S, Barton E, Padgett D, Scott G, Greenaway J, Payne BA, Burton-Fanning S, Waugh S, Raviprakash V, Sheriff N, Blakey V, Williams LA, Moore J, Stonehouse S, Smith L, Davidson RK, Bedford L, Coupland L, Wright V, Chappell JG, Tsoleridis T, Ball J, Khakh M, Fleming VM, Lister MM, Howson-Wells HC, Berry L, Boswell T, Joseph A, Willingham I, Duckworth N, Walsh S, Wise E, Moore N, Mori M, Cortes N, Kidd S, Bmbs RW, Gifford L, Bicknell K, Wyllie S, Lloyd A, Impey R, Malone CS, Cogger BJ, Levene N, Monaghan L, Keeley AJ, Partridge DG, Raza M, Evans C, Johnson K, Betteridge E, Farr BW, Goodwin S, Quail MA, Scott C, Shirley L, Thurston SA, Rajan D, Bronner IF, Aigrain L, Redshaw NM, Lensing SV, McCarthy S, Makunin A, Balcazar CE, Gallagher MD, Williamson KA, Stanton TD, Michelsen ML, Warwick-Dugdale J, Manley R, Farbos A, Harrison JW, Sambles CM, Studholme DJ, Lackenby A, Mbisa T, Platt S, Miah S, Bibby D, Manso C, Hubb J, Dabrera G, Ramsay M, Bradshaw D, Schaefer U, Groves N, Gallagher E, Lee D, Williams D, Ellaby N, Hartman H, Manesis N, Patel V, Ledesma J, Twohig KA, Allara E, Pearson C, Cheng JKJ, Bridgewater HE, Frost LR, Taylor-Joyce G, Brown PE, Tong L, Broos A, Mair D, Nichols J, Carmichael SN, Smollett KL, Nomikou K, Aranday-Cortes E, Johnson N, Nickbakhsh S, Vamos EE, Hughes M, Rainbow L, Eccles R, Nelson C, Whitehead M, Gregory R, Gemmell M, Wierzbicki C, Webster HJ, Fisher CL, Signell AW, Betancor G, Wilson HD, Nebbia G, Flaviani F, Cerda AC, Merrill TV, Wilson RE, Cotic M, Bayzid N, Thompson T, Acheson E, Rushton S, O'Brien S, Baker DJ, Rudder S, Aydin A, Sang F, Debebe J, Francois S, Vasylyeva TI, Zamudio ME, Gutierrez B, Marchbank A, Maksimovic J, Spellman K, McCluggage K, Morgan M, Beer R, Afifi S, Workman T, Fuller W, Bresner C, Angyal A, Green LR, Parsons PJ, Tucker RM, Brown R, Whiteley M, Bonfield J, Puethe C, Whitwham A, Liddle J, Rowe W, Siveroni I, Le-Viet T, Gaskin A, Johnson R.
PMID: 34726481
Science. 2021 Nov 02;eabl9551. doi: 10.1126/science.abl9551. Epub 2021 Nov 02.

[Figure: see text].

A 3-D virtual human thermoregulatory model to predict whole-body and organ-specific heat-stress responses.

European journal of applied physiology

Unnikrishnan G, Hatwar R, Hornby S, Laxminarayan S, Gulati T, Belval LN, Giersch GEW, Kazman JB, Casa DJ, Reifman J.
PMID: 34089370
Eur J Appl Physiol. 2021 Sep;121(9):2543-2562. doi: 10.1007/s00421-021-04698-1. Epub 2021 Jun 05.

OBJECTIVE: This study aimed at assessing the risks associated with human exposure to heat-stress conditions by predicting organ- and tissue-level heat-stress responses under different exertional activities, environmental conditions, and clothing.METHODS: In this study, we developed an anatomically detailed three-dimensional...

Carbon nanogels exert multipronged attack on resistant bacteria and strongly constrain resistance evolution.

Journal of colloid and interface science

Mao JY, Miscevic D, Unnikrishnan B, Chu HW, Chou CP, Chang L, Lin HJ, Huang CC.
PMID: 34742090
J Colloid Interface Sci. 2022 Feb 15;608:1813-1826. doi: 10.1016/j.jcis.2021.10.107. Epub 2021 Oct 21.

Developing antimicrobial agents that can eradicate drug-resistant (DR) bacteria and provide sustained protection from DR bacteria is a major challenge. Herein, we report a mild pyrolysis approach to prepare carbon nanogels (CNGs) through polymerization and the partial carbonization of...

Diaphragmatic ultrasound: Prospects as a tool to assess respiratory muscle involvement in amyotrophic lateral sclerosis.

Journal of clinical ultrasound : JCU

Rajula RR, Saini J, Unnikrishnan G, Vengalil S, Nashi S, Bardhan M, Huddar A, Chawla T, Sindhu DM, Ganaraja VH, Polavarapu K, Preethish-Kumar V, Kandavel T, Sathyaprabha TN, Nalini A.
PMID: 34609007
J Clin Ultrasound. 2021 Oct 05; doi: 10.1002/jcu.23069. Epub 2021 Oct 05.

BACKGROUND: Ultrasonography (USG) of the diaphragm is a promising alternative to pulmonary function tests (PFT) for assessing respiratory function in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND).METHODS: We studied 33 patients fulfilling Awaji criteria (definite = 14; probable = 12;...

Development of strategies to support home-based exercise adherence after stroke: a Delphi consensus.

BMJ open

Mahmood A, Deshmukh A, Natarajan M, Marsden D, Vyslysel G, Padickaparambil S, Ts S, Direito A, Kumaran S, N G, Sachdev H, Kumar Veluswamy S, Karthikbabu S, Unnikrishnan B, English C, Solomon JM.
PMID: 34992120
BMJ Open. 2022 Jan 06;12(1):e055946. doi: 10.1136/bmjopen-2021-055946.

OBJECTIVE: To develop a set of strategies to enhance adherence to home-based exercises after stroke, and an overarching framework to classify these strategies.METHOD: We conducted a four-round Delphi consensus (two online surveys, followed by a focus group then a...

Congenital long QT syndrome and patent ductus arteriosus: A rare surgical scenario.

Annals of pediatric cardiology

Raja J, Menon S, Venkata DB, Unnikrishnan KP, Namboodiri N.
PMID: 33679068
Ann Pediatr Cardiol. 2021 Jan-Mar;14(1):85-87. doi: 10.4103/apc.APC_146_19. Epub 2020 Sep 23.

Congenital long QT syndrome (LQTS) is a rare cardiac condition characterized by abnormality of either sodium or potassium ion channels resulting in prolongation of QT interval and thereby predisposing to life-threatening arrhythmia. Once the syndrome is diagnosed, measures should...

In Silico Protein-Protein Interaction of Pterois volitans Venom with Cancer Inducers of Helicobacter pylori.

Applied biochemistry and biotechnology

Ravi GN, Navabshan I, Unnikrishnan S, Ramalingam K.
PMID: 34843077
Appl Biochem Biotechnol. 2022 Jan;194(1):354-367. doi: 10.1007/s12010-021-03763-x. Epub 2021 Nov 29.

Gastric cancer is a pathological condition induced by the bacteria Helicobacter pylori. Targeting the key virulence factors of H. pylori causing gastric cancer is a promising method for treating gastric cancer. Recently, research has been focused on analyzing the...

Showing 445 to 455 of 455 entries