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Showing 13 to 24 of 179 entries
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Targeting Pyruvate Kinase M2 and Lactate Dehydrogenase A Is an Effective Combination Strategy for the Treatment of Pancreatic Cancer.

Cancers

Mohammad GH, Vassileva V, Acedo P, Olde Damink SWM, Malago M, Dhar DK, Pereira SP.
PMID: 31527446
Cancers (Basel). 2019 Sep 16;11(9). doi: 10.3390/cancers11091372.

Reprogrammed glucose metabolism is one of the hallmarks of cancer, and increased expression of key glycolytic enzymes, such as pyruvate kinase M2 (PKM2) and lactate dehydrogenase A (LDHA), has been associated with poor prognosis in various malignancies. Targeting these...

Stress Related Shift Toward Inflammaging in Cosmonauts After Long-Duration Space Flight.

Frontiers in physiology

Buchheim JI, Matzel S, Rykova M, Vassilieva G, Ponomarev S, Nichiporuk I, Hörl M, Moser D, Biere K, Feuerecker M, Schelling G, Thieme D, Kaufmann I, Thiel M, Choukèr A.
PMID: 30873038
Front Physiol. 2019 Feb 19;10:85. doi: 10.3389/fphys.2019.00085. eCollection 2019.

Space flight exerts a specific conglomerate of stressors on humans that can modulate the immune system. The mechanism remains to be elucidated and the consequences for cosmonauts in the long term are unclear. Most of the current research stems...

Validation of the Levenson Self-Report Psychopathy Scale in Bulgarian Substance-Dependent Individuals.

Frontiers in psychology

Psederska E, Yankov GP, Bozgunov K, Popov V, Vasilev G, Vassileva J.
PMID: 32581949
Front Psychol. 2020 Jun 09;11:1110. doi: 10.3389/fpsyg.2020.01110. eCollection 2020.

The co-occurrence of psychopathy and substance use disorders (SUDs) is associated with higher relapse rates and increased risk of violent offending. Studies on the validity of psychopathy measures in community samples and substance-dependent individuals (SDIs) are scarce. The aim...

Polyhexamethylene Biguanide:Polyurethane Blend Nanofibrous Membranes for Wound Infection Control.

Polymers

Worsley A, Vassileva K, Tsui J, Song W, Good L.
PMID: 31121845
Polymers (Basel). 2019 May 22;11(5). doi: 10.3390/polym11050915.

Polyhexamethylene biguanide (PHMB) is a broad-spectrum antiseptic which avoids many efficacy and toxicity problems associated with antimicrobials, in particular, it has a low risk of loss of susceptibility due to acquired antimicrobial resistance. Despite such advantages, PHMB is not...

Development and characterization of polyethylene glycol-carbon nanotube hydrogel composite.

Journal of materials chemistry. B

Shah K, Vasileva D, Karadaghy A, Zustiak SP.
PMID: 32262903
J Mater Chem B. 2015 Oct 28;3(40):7950-7962. doi: 10.1039/c5tb01047k. Epub 2015 Aug 14.

Carbon nanotube (CNT)-hydrogel composites are attractive for a variety of neural tissue engineering and drug delivery applications as well as biosensor coatings, transducers and leads. Both materials contribute unique and beneficial properties to the composites. Hydrogels are an excellent...

Relationships Between Alexithymia and Psychopathy in Heroin Dependent Individuals.

Frontiers in psychology

Psederska E, Savov S, Atanassov N, Vassileva J.
PMID: 31649591
Front Psychol. 2019 Oct 09;10:2269. doi: 10.3389/fpsyg.2019.02269. eCollection 2019.

BACKGROUND: Psychopathy and substance use disorders are highly co-morbid and their co-occurrence is associated with higher severity of addictive behavior and increased risk of violent offending. Both substance use disorders and psychopathy are related to prominent impairments in emotion...

Optimisation and standardisation of a multiplex immunoassay of diverse .

Wellcome open research

Wu L, Hall T, Ssewanyana I, Oulton T, Patterson C, Vasileva H, Singh S, Affara M, Mwesigwa J, Correa S, Bah M, D'Alessandro U, Sepúlveda N, Drakeley C, Tetteh KKA.
PMID: 32518839
Wellcome Open Res. 2020 Apr 23;4:26. doi: 10.12688/wellcomeopenres.14950.2. eCollection 2019.

No abstract available.

Addressing intersectional stigma as a care barrier for HIV-positive people who inject drugs: Design of an RCT in St. Petersburg, Russia.

Contemporary clinical trials communications

Rossi SL, Sereda Y, Luoma JB, Pavlov N, Toussova O, Vasileva J, Abramova K, Bendiks S, Kiriazova T, Vetrova M, Blokhina E, Krupitsky E, Lioznov D, Lodi S, Lunze K.
PMID: 34888430
Contemp Clin Trials Commun. 2021 Nov 19;24:100861. doi: 10.1016/j.conctc.2021.100861. eCollection 2021 Dec.

BACKGROUND: HIV-positive people who inject drugs (PWID) experience stigma related to their substance use and HIV, with adverse consequences to their health care utilization and mental health. To help affected individuals cope with their intersectional stigma and reduce its...

Zeb1-mediated autophagy enhances resistance of breast cancer cells to genotoxic drugs.

Biochemical and biophysical research communications

Fedorova O, Daks A, Parfenyev S, Shuvalov O, Netsvetay S, Vasileva J, Gudovich A, Golotin V, Semenov O, Petukhov A, Baiduik E, Berdigaliyev N, Tulchinsky EM, Barlev NA.
PMID: 34883287
Biochem Biophys Res Commun. 2021 Nov 26;589:29-34. doi: 10.1016/j.bbrc.2021.11.088. Epub 2021 Nov 26.

Autophagy is a highly conserved process of cellular self-digestion that involves the formation of autophagosomes for the delivery of intracellular components and dysfunctional organelles to lysosomes. This process is induced by different signals including starvation, mitochondrial dysfunction, and DNA...

Disinfection of polymicrobial urines by electrochemical oxidation: Removal of antibiotic-resistant bacteria and genes.

Journal of hazardous materials

Herraiz-Carboné M, Cotillas S, Lacasa E, Vasileva M, Sainz de Baranda C, Riquelme E, Cañizares P, Sáez C.
PMID: 34923384
J Hazard Mater. 2021 Dec 08;426:128028. doi: 10.1016/j.jhazmat.2021.128028. Epub 2021 Dec 08.

In this work, data obtained from the University Hospital Complex of Albacete (Spain) were selected as a case study to carry out the disinfection experiments. To do this, different configurations of electrochemical reactors were tested for the disinfection of...

Divergent changes: abstinence and higher-frequency substance use increase among racial/ethnic minority young adults during the COVID-19 global pandemic.

The American journal of drug and alcohol abuse

Hicks TA, Chartier KG, Buckley TD, Reese D, Working Group TSFS, Vassileva J, Dick DM, Amstadter AB, Peterson RE, Moreno O.
PMID: 35007453
Am J Drug Alcohol Abuse. 2022 Jan 10;1-12. doi: 10.1080/00952990.2021.1995401. Epub 2022 Jan 10.

BACKGROUND: Identifying factors influencing substance use among racial/ethnic minorities (REM) is important given the disproportionate impact of the COVID-19 pandemic on this population.OBJECTIVES: We examined factors in four domains and hypothesized that poor mental health, negative coping behaviors, negative...

The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau.

The American journal of tropical medicine and hygiene

McGregor D, Texeira da Silva E, Grignard L, Goncalves A, Vasileva H, Mabey D, Last A.
PMID: 33782209
Am J Trop Med Hyg. 2021 Mar 29; doi: 10.4269/ajtmh.20-1029. Epub 2021 Mar 29.

Distribution of long-lasting insecticide-treated nets (LLINs), passive detection and treatment with artemisinin-based combination therapy (ACT), and intermittent preventive treatment in pregnancy (IPTp) are the mainstay malaria control measures of Guinea-Bissau's national control programme. This study aimed to estimate the...

Showing 13 to 24 of 179 entries