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Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage.

Hepatology communications

Koelmel JP, Tan WY, Li Y, Bowden JA, Ahmadireskety A, Patt AC, Orlicky DJ, Mathé E, Kroeger NM, Thompson DC, Cochran JA, Golla JP, Kandyliari A, Chen Y, Charkoftaki G, Guingab-Cagmat JD, Tsugawa H, Arora A, Veselkov K, Kato S, Otoki Y, Nakagawa K, Yost RA, Garrett TJ, Vasilou V.
PMID: 34811964
Hepatol Commun. 2021 Nov 23; doi: 10.1002/hep4.1825. Epub 2021 Nov 23.

Alcoholic fatty liver disease (AFLD) is characterized by lipid accumulation and inflammation and can progress to cirrhosis and cancer in the liver. AFLD diagnosis currently relies on histological analysis of liver biopsies. Early detection permits interventions that would prevent...

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Koelmel JP, Tan WY, Li Y, et al. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatol Commun. 2021;doi: 10.1002/hep4.1825.
Koelmel, J. P., Tan, W. Y., Li, Y., Bowden, J. A., Ahmadireskety, A., Patt, A. C., Orlicky, D. J., Mathé, E., Kroeger, N. M., Thompson, D. C., Cochran, J. A., Golla, J. P., Kandyliari, A., Chen, Y., Charkoftaki, G., Guingab-Cagmat, J. D., Tsugawa, H., Arora, A., Veselkov, K., Kato, S., Otoki, Y., Nakagawa, K., Yost, R. A., Garrett, T. J., & Vasilou, V. (2021). Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatology communications, . https://doi.org/10.1002/hep4.1825
Koelmel, Jeremy P, et al. "Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage." Hepatology communications vol. (2021). doi: https://doi.org/10.1002/hep4.1825
Koelmel JP, Tan WY, Li Y, Bowden JA, Ahmadireskety A, Patt AC, Orlicky DJ, Mathé E, Kroeger NM, Thompson DC, Cochran JA, Golla JP, Kandyliari A, Chen Y, Charkoftaki G, Guingab-Cagmat JD, Tsugawa H, Arora A, Veselkov K, Kato S, Otoki Y, Nakagawa K, Yost RA, Garrett TJ, Vasilou V. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatol Commun. 2021 Nov 23; doi: 10.1002/hep4.1825. Epub 2021 Nov 23. PMID: 34811964.
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Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines.

Metabolomics : Official journal of the Metabolomic Society

Varshavi D, Varshavi D, McCarthy N, Veselkov K, Keun HC, Everett JR.
PMID: 34822010
Metabolomics. 2021 Nov 25;17(12):104. doi: 10.1007/s11306-021-01852-w.

INTRODUCTION: KRAS was one of the earliest human oncogenes to be described and is one of the most commonly mutated genes in different human cancers, including colorectal cancer. Despite KRAS mutants being known driver mutations, KRAS has proved difficult...

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Varshavi D, Varshavi D, McCarthy N, et al. Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics. 2021;17(12):104doi: 10.1007/s11306-021-01852-w.
Varshavi, D., Varshavi, D., McCarthy, N., Veselkov, K., Keun, H. C., & Everett, J. R. (2021). Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics : Official journal of the Metabolomic Society, 17(12), 104. https://doi.org/10.1007/s11306-021-01852-w
Varshavi, Dorna, et al. "Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines." Metabolomics : Official journal of the Metabolomic Society vol. 17,12 (2021): 104. doi: https://doi.org/10.1007/s11306-021-01852-w
Varshavi D, Varshavi D, McCarthy N, Veselkov K, Keun HC, Everett JR. Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics. 2021 Nov 25;17(12):104. doi: 10.1007/s11306-021-01852-w. PMID: 34822010; PMCID: PMC8616861.
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Predicting anticancer hyperfoods with graph convolutional networks.

Human genomics

Gonzalez G, Gong S, Laponogov I, Bronstein M, Veselkov K.
PMID: 34099048
Hum Genomics. 2021 Jun 07;15(1):33. doi: 10.1186/s40246-021-00333-4.

BACKGROUND: Recent efforts in the field of nutritional science have allowed the discovery of disease-beating molecules within foods based on the commonality of bioactive food molecules to FDA-approved drugs. The pioneering work in this field used an unsupervised network...

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Gonzalez G, Gong S, Laponogov I, et al. Predicting anticancer hyperfoods with graph convolutional networks. Hum Genomics. 2021;15(1):33doi: 10.1186/s40246-021-00333-4.
Gonzalez, G., Gong, S., Laponogov, I., Bronstein, M., & Veselkov, K. (2021). Predicting anticancer hyperfoods with graph convolutional networks. Human genomics, 15(1), 33. https://doi.org/10.1186/s40246-021-00333-4
Gonzalez, Guadalupe, et al. "Predicting anticancer hyperfoods with graph convolutional networks." Human genomics vol. 15,1 (2021): 33. doi: https://doi.org/10.1186/s40246-021-00333-4
Gonzalez G, Gong S, Laponogov I, Bronstein M, Veselkov K. Predicting anticancer hyperfoods with graph convolutional networks. Hum Genomics. 2021 Jun 07;15(1):33. doi: 10.1186/s40246-021-00333-4. PMID: 34099048; PMCID: PMC8182908.
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Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage.

Hepatology communications

Koelmel JP, Tan WY, Li Y, Bowden JA, Ahmadireskety A, Patt AC, Orlicky DJ, Mathé E, Kroeger NM, Thompson DC, Cochran JA, Golla JP, Kandyliari A, Chen Y, Charkoftaki G, Guingab-Cagmat JD, Tsugawa H, Arora A, Veselkov K, Kato S, Otoki Y, Nakagawa K, Yost RA, Garrett TJ, Vasiliou V.
PMID: 34811964
Hepatol Commun. 2021 Nov 23; doi: 10.1002/hep4.1825. Epub 2021 Nov 23.

Alcoholic fatty liver disease (AFLD) is characterized by lipid accumulation and inflammation and can progress to cirrhosis and cancer in the liver. AFLD diagnosis currently relies on histological analysis of liver biopsies. Early detection permits interventions that would prevent...

Cite
Koelmel JP, Tan WY, Li Y, et al. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatol Commun. 2021;doi: 10.1002/hep4.1825.
Koelmel, J. P., Tan, W. Y., Li, Y., Bowden, J. A., Ahmadireskety, A., Patt, A. C., Orlicky, D. J., Mathé, E., Kroeger, N. M., Thompson, D. C., Cochran, J. A., Golla, J. P., Kandyliari, A., Chen, Y., Charkoftaki, G., Guingab-Cagmat, J. D., Tsugawa, H., Arora, A., Veselkov, K., Kato, S., Otoki, Y., Nakagawa, K., Yost, R. A., Garrett, T. J., & Vasiliou, V. (2021). Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatology communications, . https://doi.org/10.1002/hep4.1825
Koelmel, Jeremy P, et al. "Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage." Hepatology communications vol. (2021). doi: https://doi.org/10.1002/hep4.1825
Koelmel JP, Tan WY, Li Y, Bowden JA, Ahmadireskety A, Patt AC, Orlicky DJ, Mathé E, Kroeger NM, Thompson DC, Cochran JA, Golla JP, Kandyliari A, Chen Y, Charkoftaki G, Guingab-Cagmat JD, Tsugawa H, Arora A, Veselkov K, Kato S, Otoki Y, Nakagawa K, Yost RA, Garrett TJ, Vasiliou V. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatol Commun. 2021 Nov 23; doi: 10.1002/hep4.1825. Epub 2021 Nov 23. PMID: 34811964.
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Effect of salinity on water relations of wild barley plants differing in salt tolerance.

AoB PLANTS

Vysotskaya L, Hedley PE, Sharipova G, Veselov D, Kudoyarova G, Morris J, Jones HG.
PMID: 22476064
AoB Plants. 2010;2010:plq006. doi: 10.1093/aobpla/plq006. Epub 2010 May 16.

BACKGROUND AND AIMS: Certain lines of wild barley (Hordeum spontaneum) are more tolerant of salinity than others. The physiological basis of this difference is examined in a comparative study of a saline-tolerant and saline-intolerant line that emphasizes plant water...

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Vysotskaya L, Hedley PE, Sharipova G, et al. Effect of salinity on water relations of wild barley plants differing in salt tolerance. AoB Plants. 2010;2010:plq006doi: 10.1093/aobpla/plq006.
Vysotskaya, L., Hedley, P. E., Sharipova, G., Veselov, D., Kudoyarova, G., Morris, J., & Jones, H. G. (2010). Effect of salinity on water relations of wild barley plants differing in salt tolerance. AoB PLANTS, 2010plq006. https://doi.org/10.1093/aobpla/plq006
Vysotskaya, Lidia, et al. "Effect of salinity on water relations of wild barley plants differing in salt tolerance." AoB PLANTS vol. 2010 (2010): plq006. doi: https://doi.org/10.1093/aobpla/plq006
Vysotskaya L, Hedley PE, Sharipova G, Veselov D, Kudoyarova G, Morris J, Jones HG. Effect of salinity on water relations of wild barley plants differing in salt tolerance. AoB Plants. 2010;2010:plq006. doi: 10.1093/aobpla/plq006. Epub 2010 May 16. PMID: 22476064; PMCID: PMC3000697.
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Cytokinin flows from Hordeum vulgare to the hemiparasite Rhinanthus minor and the influence of infection on host and parasite cytokinins relations.

Functional plant biology : FPB

Jiang F, Veselova S, Veselov D, Kudoyarova G, Jeschke WD, Hartung W.
PMID: 32689161
Funct Plant Biol. 2005 Aug;32(7):619-629. doi: 10.1071/FP04168.

Using the facultative root hemiparasite Rhinanthus minor L. and Hordeum vulgare L. as a host, the flows, depositions and metabolism of zeatin-type cytokinins [zeatin (Z), zeatin riboside (ZR), zeatin nucleotide (ZN)] within the host, the parasite and between host...

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Jiang F, Veselova S, Veselov D, et al. Cytokinin flows from Hordeum vulgare to the hemiparasite Rhinanthus minor and the influence of infection on host and parasite cytokinins relations. Funct Plant Biol. 2005;32(7):619-629doi: 10.1071/FP04168.
Jiang, F., Veselova, S., Veselov, D., Kudoyarova, G., Jeschke, W. D., & Hartung, W. (2005). Cytokinin flows from Hordeum vulgare to the hemiparasite Rhinanthus minor and the influence of infection on host and parasite cytokinins relations. Functional plant biology : FPB, 32(7), 619-629. https://doi.org/10.1071/FP04168
Jiang, Fan, et al. "Cytokinin flows from Hordeum vulgare to the hemiparasite Rhinanthus minor and the influence of infection on host and parasite cytokinins relations." Functional plant biology : FPB vol. 32,7 (2005): 619-629. doi: https://doi.org/10.1071/FP04168
Jiang F, Veselova S, Veselov D, Kudoyarova G, Jeschke WD, Hartung W. Cytokinin flows from Hordeum vulgare to the hemiparasite Rhinanthus minor and the influence of infection on host and parasite cytokinins relations. Funct Plant Biol. 2005 Aug;32(7):619-629. doi: 10.1071/FP04168. PMID: 32689161.
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Ultrabroad tuning range (100  nm) of external-cavity continuous-wave high-power semiconductor lasers based on a single InGaAs quantum well.

Applied optics

Podoskin A, Golovin V, Gavrina P, Veselov D, Zolotarev V, Shamakhov V, Nikolaev D, Leshko A, Slipchenko S, Pikhtin N, Kopév P.
PMID: 31873586
Appl Opt. 2019 Nov 20;58(33):9089-9093. doi: 10.1364/AO.58.009089.

An external cavity in Littrow configuration based on a reflective diffraction grating and a high-power semiconductor laser based on an asymmetric heterostructure with low optical loss was studied. A continuous-wave optical output power of 13 W with a linewidth...

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Podoskin A, Golovin V, Gavrina P, et al. Ultrabroad tuning range (100  nm) of external-cavity continuous-wave high-power semiconductor lasers based on a single InGaAs quantum well. Appl Opt. 2019;58(33):9089-9093doi: 10.1364/AO.58.009089.
Podoskin, A., Golovin, V., Gavrina, P., Veselov, D., Zolotarev, V., Shamakhov, V., Nikolaev, D., Leshko, A., Slipchenko, S., Pikhtin, N., & Kopév, P. (2019). Ultrabroad tuning range (100  nm) of external-cavity continuous-wave high-power semiconductor lasers based on a single InGaAs quantum well. Applied optics, 58(33), 9089-9093. https://doi.org/10.1364/AO.58.009089
Podoskin, Alexandr, et al. "Ultrabroad tuning range (100  nm) of external-cavity continuous-wave high-power semiconductor lasers based on a single InGaAs quantum well." Applied optics vol. 58,33 (2019): 9089-9093. doi: https://doi.org/10.1364/AO.58.009089
Podoskin A, Golovin V, Gavrina P, Veselov D, Zolotarev V, Shamakhov V, Nikolaev D, Leshko A, Slipchenko S, Pikhtin N, Kopév P. Ultrabroad tuning range (100  nm) of external-cavity continuous-wave high-power semiconductor lasers based on a single InGaAs quantum well. Appl Opt. 2019 Nov 20;58(33):9089-9093. doi: 10.1364/AO.58.009089. PMID: 31873586.
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Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice.

Frontiers in molecular biosciences

Varshavi D, Scott FH, Varshavi D, Veeravalli S, Phillips IR, Veselkov K, Strittmatter N, Takats Z, Shephard EA, Everett JR.
PMID: 29686991
Front Mol Biosci. 2018 Apr 09;5:28. doi: 10.3389/fmolb.2018.00028. eCollection 2018.

It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene,

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Varshavi D, Scott FH, Varshavi D, et al. Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice. Front Mol Biosci. 2018;5:28doi: 10.3389/fmolb.2018.00028.
Varshavi, D., Scott, F. H., Varshavi, D., Veeravalli, S., Phillips, I. R., Veselkov, K., Strittmatter, N., Takats, Z., Shephard, E. A., & Everett, J. R. (2018). Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice. Frontiers in molecular biosciences, 528. https://doi.org/10.3389/fmolb.2018.00028
Varshavi, Dorsa, et al. "Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice." Frontiers in molecular biosciences vol. 5 (2018): 28. doi: https://doi.org/10.3389/fmolb.2018.00028
Varshavi D, Scott FH, Varshavi D, Veeravalli S, Phillips IR, Veselkov K, Strittmatter N, Takats Z, Shephard EA, Everett JR. Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice. Front Mol Biosci. 2018 Apr 09;5:28. doi: 10.3389/fmolb.2018.00028. eCollection 2018. PMID: 29686991; PMCID: PMC5900034.
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Exogenous application of abscisic acid (ABA) increases root and cell hydraulic conductivity and abundance of some aquaporin isoforms in the ABA-deficient barley mutant Az34.

Annals of botany

Sharipova G, Veselov D, Kudoyarova G, Fricke W, Dodd IC, Katsuhara M, Furuichi T, Ivanov I, Veselov S.
PMID: 27358289
Ann Bot. 2016 Oct 01;118(4):777-785. doi: 10.1093/aob/mcw117.

Background and Aims Regulation of water channel aquaporins (AQPs) provides another mechanism by which abscisic acid (ABA) may influence water flow through plants. To the best of our knowledge, no studies have addressed the changes in ABA levels, the...

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Sharipova G, Veselov D, Kudoyarova G, et al. Exogenous application of abscisic acid (ABA) increases root and cell hydraulic conductivity and abundance of some aquaporin isoforms in the ABA-deficient barley mutant Az34. Ann Bot. 2016;118(4):777-785doi: 10.1093/aob/mcw117.
Sharipova, G., Veselov, D., Kudoyarova, G., Fricke, W., Dodd, I. C., Katsuhara, M., Furuichi, T., Ivanov, I., & Veselov, S. (2016). Exogenous application of abscisic acid (ABA) increases root and cell hydraulic conductivity and abundance of some aquaporin isoforms in the ABA-deficient barley mutant Az34. Annals of botany, 118(4), 777-785. https://doi.org/10.1093/aob/mcw117
Sharipova, Guzel, et al. "Exogenous application of abscisic acid (ABA) increases root and cell hydraulic conductivity and abundance of some aquaporin isoforms in the ABA-deficient barley mutant Az34." Annals of botany vol. 118,4 (2016): 777-785. doi: https://doi.org/10.1093/aob/mcw117
Sharipova G, Veselov D, Kudoyarova G, Fricke W, Dodd IC, Katsuhara M, Furuichi T, Ivanov I, Veselov S. Exogenous application of abscisic acid (ABA) increases root and cell hydraulic conductivity and abundance of some aquaporin isoforms in the ABA-deficient barley mutant Az34. Ann Bot. 2016 Oct 01;118(4):777-785. doi: 10.1093/aob/mcw117. PMID: 27358289; PMCID: PMC5055630.
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research.

Gastroenterology research and practice

Koumpa FS, Xylas D, Konopka M, Galea D, Veselkov K, Antoniou A, Mehta A, Mirnezami R.
PMID: 31065262
Gastroenterol Res Pract. 2019 Apr 01;2019:5180895. doi: 10.1155/2019/5180895. eCollection 2019.

Colorectal peritoneal metastases (CPM) are associated with abbreviated survival and significantly impaired quality of life. In patients with CPM, radical multimodality treatment consisting of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has demonstrated oncological superiority over systemic...

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Koumpa FS, Xylas D, Konopka M, et al. Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research. Gastroenterol Res Pract. 2019;2019:5180895doi: 10.1155/2019/5180895.
Koumpa, F. S., Xylas, D., Konopka, M., Galea, D., Veselkov, K., Antoniou, A., Mehta, A., & Mirnezami, R. (2019). Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research. Gastroenterology research and practice, 20195180895. https://doi.org/10.1155/2019/5180895
Koumpa, Foteini Stefania, et al. "Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research." Gastroenterology research and practice vol. 2019 (2019): 5180895. doi: https://doi.org/10.1155/2019/5180895
Koumpa FS, Xylas D, Konopka M, Galea D, Veselkov K, Antoniou A, Mehta A, Mirnezami R. Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research. Gastroenterol Res Pract. 2019 Apr 01;2019:5180895. doi: 10.1155/2019/5180895. eCollection 2019. PMID: 31065262; PMCID: PMC6466888.
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Standardized nomenclature and open science in Human Genomics.

Human genomics

Vasiliou V, Veselkov K, Bruford E, Reichardt JKV.
PMID: 33612096
Hum Genomics. 2021 Feb 22;15(1):13. doi: 10.1186/s40246-021-00312-9.

No abstract available.

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Vasiliou V, Veselkov K, Bruford E, et al. Standardized nomenclature and open science in Human Genomics. Hum Genomics. 2021;15(1):13doi: 10.1186/s40246-021-00312-9.
Vasiliou, V., Veselkov, K., Bruford, E., & Reichardt, J. K. V. (2021). Standardized nomenclature and open science in Human Genomics. Human genomics, 15(1), 13. https://doi.org/10.1186/s40246-021-00312-9
Vasiliou, Vasilis, et al. "Standardized nomenclature and open science in Human Genomics." Human genomics vol. 15,1 (2021): 13. doi: https://doi.org/10.1186/s40246-021-00312-9
Vasiliou V, Veselkov K, Bruford E, Reichardt JKV. Standardized nomenclature and open science in Human Genomics. Hum Genomics. 2021 Feb 22;15(1):13. doi: 10.1186/s40246-021-00312-9. PMID: 33612096; PMCID: PMC7898730.
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Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates.

Cells

Vysotskaya L, Timergalina L, Akhiyarova G, Korobova A, Fedyaev V, Ivanov I, Kudoyarova G, Veselov D.
PMID: 34831337
Cells. 2021 Nov 10;10(11). doi: 10.3390/cells10113110.

Changes in root elongation are important for the acquisition of mineral nutrients by plants. Plant hormones, cytokinins, and abscisic acid (ABA) and their interaction are important for the control of root elongation under changes in the availability of ions....

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Vysotskaya L, Timergalina L, Akhiyarova G, et al. Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates. Cells. 2021;10(11)doi: 10.3390/cells10113110.
Vysotskaya, L., Timergalina, L., Akhiyarova, G., Korobova, A., Fedyaev, V., Ivanov, I., Kudoyarova, G., & Veselov, D. (2021). Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates. Cells, 10(11), . https://doi.org/10.3390/cells10113110
Vysotskaya, Lidiya, et al. "Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates." Cells vol. 10,11 (2021). doi: https://doi.org/10.3390/cells10113110
Vysotskaya L, Timergalina L, Akhiyarova G, Korobova A, Fedyaev V, Ivanov I, Kudoyarova G, Veselov D. Association of Barley Root Elongation with ABA-Dependent Transport of Cytokinins from Roots and Shoots under Supra-Optimal Concentrations of Nitrates and Phosphates. Cells. 2021 Nov 10;10(11). doi: 10.3390/cells10113110. PMID: 34831337; PMCID: PMC8625479.
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