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Showing 229 to 232 of 232 entries
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Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery.

Journal of controlled release : official journal of the Controlled Release Society

Melamed JR, Hajj KA, Chaudhary N, Strelkova D, Arral ML, Pardi N, Alameh MG, Miller JB, Farbiak L, Siegwart DJ, Weissman D, Whitehead KA.
PMID: 34801660
J Control Release. 2021 Nov 18;341:206-214. doi: 10.1016/j.jconrel.2021.11.022. Epub 2021 Nov 18.

Therapeutic mRNA has the potential to revolutionize the treatment of myriad diseases and, in 2020, facilitated the most rapid vaccine development in history. Among the substantial advances in mRNA technology made in recent years, the incorporation of base modifications...

Acquired Zinc Deficiency Mimicking Acrodermatitis Enteropathica in a Breast-Fed Premature Infant.

Pediatric reports

D'Amico G, De Laet C, Smits G, Salik D, Deprez G, Vilain C, Perlot P, Vicinanza A.
PMID: 34449696
Pediatr Rep. 2021 Aug 01;13(3):444-449. doi: 10.3390/pediatric13030051.

We present a case of a transient acquired zinc deficiency in a breast-fed, 4-month-old-male prematurely born infant, with acrodermatitis enteropathica-like symptoms such as crusted, eroded, erythemato-squamous eruption in periorificial and acral patterns. The laboratory investigations showed low zinc levels...

Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery.

Journal of controlled release : official journal of the Controlled Release Society

Melamed JR, Hajj KA, Chaudhary N, Strelkova D, Arral ML, Pardi N, Alameh MG, Miller JB, Farbiak L, Siegwart DJ, Weissman D, Whitehead KA.
PMID: 34801660
J Control Release. 2021 Nov 18;341:206-214. doi: 10.1016/j.jconrel.2021.11.022. Epub 2021 Nov 18.

Therapeutic mRNA has the potential to revolutionize the treatment of myriad diseases and, in 2020, facilitated the most rapid vaccine development in history. Among the substantial advances in mRNA technology made in recent years, the incorporation of base modifications...

Developing a bioethics curriculum for medical students from divergent geo-political regions.

Greenberg RA, Kim C, Stolte H, Hellmann J, Shaul RZ, Valani R, Scolnik D.
UIID-AD: 4372
2016; doi: 10.1186/s12909-016-0711-4.

BACKGROUND: The World Health Organization calls for stronger cross-cultural emphasis in medical training. Bioethics education can build such competencies as it involves the conscious exploration and application of values and principles. The International Pediatric Emergency Medicine Elective (IPEME), a...

Showing 229 to 232 of 232 entries