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Showing 13 to 24 of 38 entries
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Induced Liver Regeneration Enhances CRISPR/Cas9-Mediated Gene Repair in Tyrosinemia Type 1.

Human gene therapy

Zhang QS, Tiyaboonchai A, Nygaard S, Baradar K, Major A, Balaji N, Grompe M, Brigman G, Villares E.
PMID: 32729326
Hum Gene Ther. 2021 Mar;32(5):294-301. doi: 10.1089/hum.2020.042. Epub 2020 Oct 16.

The efficiency of gene repair by homologous recombination in the liver is enhanced by CRISP/Cas9 incision near the mutation. In this study, we explored interventions designed to further enhance

Influence of the carbohydrate-binding module on the activity of a fungal AA9 lytic polysaccharide monooxygenase on cellulosic substrates.

Biotechnology for biofuels

Chalak A, Villares A, Moreau C, Haon M, Grisel S, d'Orlando A, Herpoël-Gimbert I, Labourel A, Cathala B, Berrin JG.
PMID: 31508147
Biotechnol Biofuels. 2019 Sep 03;12:206. doi: 10.1186/s13068-019-1548-y. eCollection 2019.

BACKGROUND: Cellulose-active lytic polysaccharide monooxygenases (LPMOs) secreted by filamentous fungi play a key role in the degradation of recalcitrant lignocellulosic biomass. They can occur as multidomain proteins fused to a carbohydrate-binding module (CBM). From a biotech perspective, LPMOs are...

Atypical hyperglycemia presentation suggests considering a diagnostic of other types of diabetes: first reported GCK-MODY in Perú.

Clinical diabetes and endocrinology

Lizarzaburu-Robles JC, Gomez-de-la-Torre JC, Castro-Mujica MDC, Vento F, Villanes S, Salsavilca E, Guerin C.
PMID: 31956423
Clin Diabetes Endocrinol. 2020 Jan 14;6:3. doi: 10.1186/s40842-019-0091-x. eCollection 2020.

BACKGROUND: Prevalence of maturity-onset diabetes of the young (MODY) is estimated between 1 and 2% of all diabetes cases. In Latin-America little information has been described about the frequency of the disease, perhaps due to limited access to genetic...

Entering the Uncertainty of Residency.

MD advisor : a journal for New Jersey medical community

Villars M.
PMID: 27603773
MD Advis. 2016;9(3):36.

No abstract available.

Dentinogenic ghost cell tumor - Case report of a rare entity.

International journal of surgery case reports

Salgado I, Vilares M, Nogueira R, Rito M, Rosa F, Gomes P.
PMID: 33773371
Int J Surg Case Rep. 2021 Apr;81:105651. doi: 10.1016/j.ijscr.2021.105651. Epub 2021 Feb 15.

INTRODUCTION: Dentinogenic ghost cell tumor (DGCT) is an entity with about 60 cases reported in the literature. It is a benign odontogenic tumor, despite being locally invasive and associated with a risk of local recurrence.PRESENTATION OF CASE: A 47-year-old...

Free-living marine nematodes from San Antonio Bay (Río Negro, Argentina).

ZooKeys

Villares G, Lo Russo V, Pastor de Ward C, Milano V, Miyashiro L, Mazzanti R.
PMID: 27110176
Zookeys. 2016 Mar 28;(574):43-55. doi: 10.3897/zookeys.574.7222. eCollection 2016.

The dataset of free-living marine nematodes of San Antonio Bay is based on sediment samples collected in February 2009 during doctoral theses funded by CONICET grants. A total of 36 samples has been taken at three locations in the...

Divergent growth of poly(amidoamine) dendrimer-like branched polymers at the reducing end of cellulose nanocrystals.

Carbohydrate polymers

Chemin M, Moreau C, Cathala B, Villares A.
PMID: 34980353
Carbohydr Polym. 2022 Mar 01;279:119008. doi: 10.1016/j.carbpol.2021.119008. Epub 2021 Dec 15.

This paper presents the growth of dendritic polymers at the reducing ends of cellulose nanocrystals by the "grafting from" approach. We took advantage of the chemically differentiated ends of cellulose nanocrystals to specifically synthesize dendrimers at their reducing end...

Emerging roles of PAR-1 and PAFR in melanoma metastasis.

Cancer microenvironment : official journal of the International Cancer Microenvironment Society

Melnikova VO, Villares GJ, Bar-Eli M.
PMID: 19308689
Cancer Microenviron. 2008 Dec;1(1):103-11. doi: 10.1007/s12307-008-0002-7. Epub 2008 Feb 20.

Melanoma growth, angiogenesis and metastatic progression are strongly promoted by the inflammatory tumor microenvironment due to high levels of cytokine and chemokine secretion by the recruited inflammatory and stromal cells. In addition, platelets and molecular components of procoagulant pathways...

Higher-Order Pattern Anti-Unification in Linear Time.

Journal of automated reasoning

Baumgartner A, Kutsia T, Levy J, Villaret M.
PMID: 30174364
J Autom Reason. 2017;58(2):293-310. doi: 10.1007/s10817-016-9383-3. Epub 2016 Jul 27.

We present a rule-based Huet's style anti-unification algorithm for simply typed lambda-terms, which computes a least general higher-order pattern generalization. For a pair of arbitrary terms of the same type, such a generalization always exists and is unique modulo

Correction to: Atypical hyperglycemia presentation suggests considering a diagnostic of other types of diabetes: first reported GCK-MODY in Perú.

Clinical diabetes and endocrinology

Lizarzaburu-Robles JC, Gomez-de-la-Torre JC, Del Carmen Castro-Mujica M, Vento F, Villanes S, Salsavilca E, Guerin C.
PMID: 32099664
Clin Diabetes Endocrinol. 2020 Feb 17;6:4. doi: 10.1186/s40842-020-0093-8. eCollection 2020.

[This corrects the article DOI: 10.1186/s40842-019-0091-x.].

Status of Cytomegalovirus Prevention and Treatment in 2000.

Hematology. American Society of Hematology. Education Program

Zaia JA, Sissons JG, Riddell S, Diamond DJ, Wills MR, Carmichael AJ, Weekes MP, Gandhi M, La Rosa C, Villacres M, Lacey S, Markel S, Sun J.
PMID: 11701550
Hematology Am Soc Hematol Educ Program. 2000;339-355. doi: 10.1182/asheducation-2000.1.339.

Cytomegalovirus (CMV) infection continues to be a problem in selected populations following hematopoietic stem cell transplantation (SCT). Although there have been no new antiviral agents for management of this infection in recent years, the methods for using the existing...

Use of Lentiviral Particles As a Cell Membrane-Based mFasL Delivery System for .

Frontiers in immunology

Rodríguez-Frade JM, Guedán A, Lucas P, Martínez-Muñoz L, Villares R, Criado G, Balomenos D, Reyburn HT, Mellado M.
PMID: 28484458
Front Immunol. 2017 Apr 21;8:460. doi: 10.3389/fimmu.2017.00460. eCollection 2017.

During budding, lentiviral particles (LVP) incorporate cell membrane proteins in the viral envelope. We explored the possibility of harnessing this process to generate LVP-expressing membrane proteins of therapeutic interest and studied the potential of these tools to treat different...

Showing 13 to 24 of 38 entries