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Showing 241 to 246 of 246 entries
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Stability of Superdiffusion in Nearly Integrable Spin Chains.

Physical review letters

De Nardis J, Gopalakrishnan S, Vasseur R, Ware B.
PMID: 34397245
Phys Rev Lett. 2021 Jul 30;127(5):057201. doi: 10.1103/PhysRevLett.127.057201.

Superdiffusive finite-temperature transport has been recently observed in a variety of integrable systems with non-Abelian global symmetries. Superdiffusion is caused by giant Goldstone-like quasiparticles stabilized by integrability. Here, we argue that these giant quasiparticles remain long-lived and give divergent...

Tapentadol and oxycodone reduce cingulate glutamate in healthy volunteers.

British journal of clinical pharmacology

Hansen TM, Frøkjaer JB, Mark EB, Drewes AM.
PMID: 34427941
Br J Clin Pharmacol. 2021 Aug 24; doi: 10.1111/bcp.15050. Epub 2021 Aug 24.

Tapentadol and oxycodone are commonly used analgesics. Preclinical studies have shown that oxycodone modulates brain metabolites related to opioid pathways, whereas tapentadol also affects noradrenergic activity. However, knowledge about the function of the medications in the human brain is...

Type 2 Diabetes and Cognitive Status in the Health and Retirement Study: A Mendelian Randomization Approach.

Frontiers in genetics

Ware EB, Morataya C, Fu M, Bakulski KM.
PMID: 33868373
Front Genet. 2021 Mar 25;12:634767. doi: 10.3389/fgene.2021.634767. eCollection 2021.

BACKGROUND: Type 2 diabetes mellitus (T2DM) and dementia are leading causes of mortality and disability in the US. T2DM has been associated with dementia; however, causality has not been clearly established. This study tested inferred causality between T2DM and...

Linear Association Between Hypoalbuminemia and Increased Risk of Acute Respiratory Distress Syndrome in Critically Ill Adults.

Critical care explorations

McNeil JB, Jackson KE, Wang C, Siew ED, Vincz AJ, Shaver CM, Bastarache JA, Ware LB.
PMID: 34549190
Crit Care Explor. 2021 Sep 14;3(9):e0527. doi: 10.1097/CCE.0000000000000527. eCollection 2021 Sep.

We hypothesized that low serum albumin would contribute to pulmonary edema formation, thereby independently increasing the risk of developing acute respiratory distress syndrome in critically ill patients.DESIGN: Retrospective analysis of prospective cohort.SETTING: Medical, surgical, and cardiovascular ICUs at Vanderbilt...

Association of low-frequency and rare coding variants with information processing speed.

Translational psychiatry

Bressler J, Davies G, Smith AV, Saba Y, Bis JC, Jian X, Hayward C, Yanek L, Smith JA, Mirza SS, Wang R, Adams HHH, Becker D, Boerwinkle E, Campbell A, Cox SR, Eiriksdottir G, Fawns-Ritchie C, Gottesman RF, Grove ML, Guo X, Hofer E, Kardia SLR, Knol MJ, Koini M, Lopez OL, Marioni RE, Nyquist P, Pattie A, Polasek O, Porteous DJ, Rudan I, Satizabal CL, Schmidt H, Schmidt R, Sidney S, Simino J, Smith BH, Turner ST, van der Lee SJ, Ware EB, Whitmer RA, Yaffe K, Yang Q, Zhao W, Gudnason V, Launer LJ, Fitzpatrick AL, Psaty BM, Fornage M, Arfan Ikram M, van Duijn CM, Seshadri S, Mosley TH, Deary IJ.
PMID: 34864818
Transl Psychiatry. 2021 Dec 04;11(1):613. doi: 10.1038/s41398-021-01736-6.

Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare...

Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study.

Thorax

Sinha P, Delucchi KL, Chen Y, Zhuo H, Abbott J, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Calfee CS.
PMID: 34253679
Thorax. 2022 Jan;77(1):13-21. doi: 10.1136/thoraxjnl-2021-217158. Epub 2021 Jul 12.

RATIONALE: Using latent class analysis (LCA), two subphenotypes of acute respiratory distress syndrome (ARDS) have consistently been identified in five randomised controlled trials (RCTs), with distinct biological characteristics, divergent outcomes and differential treatment responses to randomised interventions. Their existence...

Showing 241 to 246 of 246 entries