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The expansion of human T-bet.

Science immunology

Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.
PMID: 34623902
Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08.

[Figure: see text].

Cite
Keller B, Strohmeier V, Harder I, et al. The expansion of human T-bet. Sci Immunol. 2021;6(64):eabh0891doi: 10.1126/sciimmunol.abh0891.
Keller, B., Strohmeier, V., Harder, I., Unger, S., Payne, K. J., Andrieux, G., Boerries, M., Felixberger, P. T., Landry, J. J. M., Nieters, A., Rensing-Ehl, A., Salzer, U., Frede, N., Usadel, S., Elling, R., Speckmann, C., Hainmann, I., Ralph, E., Gilmour, K., Wentink, M. W. J., van der Burg, M., Kuehn, H. S., Rosenzweig, S. D., Kölsch, U., von Bernuth, H., Kaiser-Labusch, P., Gothe, F., Hambleton, S., Vlagea, A. D., Garcia Garcia, A., Alsina, L., Markelj, G., Avcin, T., Vasconcelos, J., Guedes, M., Ding, J. Y., Ku, C. L., Shadur, B., Avery, D. T., Venhoff, N., Thiel, J., Becker, H., Erazo-Borrás, L., Trujillo-Vargas, C. M., Franco, J. L., Fieschi, C., Okada, S., Gray, P. E., Uzel, G., Casanova, J. L., Fliegauf, M., Grimbacher, B., Eibel, H., Ehl, S., Voll, R. E., Rizzi, M., Stepensky, P., Benes, V., Ma, C. S., Bossen, C., Tangye, S. G., & Warnatz, K. (2021). The expansion of human T-bet. Science immunology, 6(64), eabh0891. https://doi.org/10.1126/sciimmunol.abh0891
Keller, Baerbel, et al. "The expansion of human T-bet." Science immunology vol. 6,64 (2021): eabh0891. doi: https://doi.org/10.1126/sciimmunol.abh0891
Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K. The expansion of human T-bet. Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08. PMID: 34623902.
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[No title available]

Pharmaceuticals (Basel, Switzerland)

Wanat K, Żydek G, Hekner A, Brzezińska E.
PMID: 33671019
Pharmaceuticals (Basel). 2021 Feb 28;14(3). doi: 10.3390/ph14030202.

Plasma protein binding is an important determinant of the pharmacokinetic properties of chemical compounds in living organisms. The aim of the present study was to determine the index of protein binding affinity based on chromatographic experiments. The question is...

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Wanat K, Żydek G, Hekner A, et al. . Pharmaceuticals (Basel). 2021;14(3)doi: 10.3390/ph14030202.
Wanat, K., Żydek, G., Hekner, A., & Brzezińska, E. (2021). . Pharmaceuticals (Basel, Switzerland), 14(3), . https://doi.org/10.3390/ph14030202
Wanat, Karolina, et al. "." Pharmaceuticals (Basel, Switzerland) vol. 14,3 (2021). doi: https://doi.org/10.3390/ph14030202
Wanat K, Żydek G, Hekner A, Brzezińska E. . Pharmaceuticals (Basel). 2021 Feb 28;14(3). doi: 10.3390/ph14030202. PMID: 33671019; PMCID: PMC7997166.
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The expansion of human T-bet.

Science immunology

Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.
PMID: 34623902
Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08.

[Figure: see text].

Cite
Keller B, Strohmeier V, Harder I, et al. The expansion of human T-bet. Sci Immunol. 2021;6(64):eabh0891doi: 10.1126/sciimmunol.abh0891.
Keller, B., Strohmeier, V., Harder, I., Unger, S., Payne, K. J., Andrieux, G., Boerries, M., Felixberger, P. T., Landry, J. J. M., Nieters, A., Rensing-Ehl, A., Salzer, U., Frede, N., Usadel, S., Elling, R., Speckmann, C., Hainmann, I., Ralph, E., Gilmour, K., Wentink, M. W. J., van der Burg, M., Kuehn, H. S., Rosenzweig, S. D., Kölsch, U., von Bernuth, H., Kaiser-Labusch, P., Gothe, F., Hambleton, S., Vlagea, A. D., Garcia Garcia, A., Alsina, L., Markelj, G., Avcin, T., Vasconcelos, J., Guedes, M., Ding, J. Y., Ku, C. L., Shadur, B., Avery, D. T., Venhoff, N., Thiel, J., Becker, H., Erazo-Borrás, L., Trujillo-Vargas, C. M., Franco, J. L., Fieschi, C., Okada, S., Gray, P. E., Uzel, G., Casanova, J. L., Fliegauf, M., Grimbacher, B., Eibel, H., Ehl, S., Voll, R. E., Rizzi, M., Stepensky, P., Benes, V., Ma, C. S., Bossen, C., Tangye, S. G., & Warnatz, K. (2021). The expansion of human T-bet. Science immunology, 6(64), eabh0891. https://doi.org/10.1126/sciimmunol.abh0891
Keller, Baerbel, et al. "The expansion of human T-bet." Science immunology vol. 6,64 (2021): eabh0891. doi: https://doi.org/10.1126/sciimmunol.abh0891
Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K. The expansion of human T-bet. Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08. PMID: 34623902.
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Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group.

Journal of clinical immunology

Schütz K, Alecsandru D, Grimbacher B, Haddock J, Bruining A, Driessen G, de Vries E, van Hagen PM, Hartmann I, Fraioli F, Milito C, Mitrevski M, Quinti I, Serra G, Kelleher P, Loebinger M, Litzman J, Postranecka V, Thon V, Babar J, Condliffe AM, Exley A, Kumararatne D, Screaton N, Jones A, Bondioni MP, Lougaris V, Plebani A, Soresina A, Sirignano C, Spadaro G, Galal N, Gonzalez-Granado LI, Dettmer S, Stirling R, Chapel H, Lucas M, Patel S, Farber CM, Meyts I, Banerjee AK, Hackett S, Hurst JR, Warnatz K, Gathmann B, Weidemann J, Berthold D, Baumann U.
PMID: 30905051
J Clin Immunol. 2019 Feb;39(2):225-227. doi: 10.1007/s10875-019-00609-4.

In the original version of this article unfortunately two authors were missing: Dr. Jürgen Weidemann and Dr. Daniel Berthold. The correct list of authors is presented above.

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Schütz K, Alecsandru D, Grimbacher B, et al. Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. J Clin Immunol. 2019;39(2):225-227doi: 10.1007/s10875-019-00609-4.
Schütz, K., Alecsandru, D., Grimbacher, B., Haddock, J., Bruining, A., Driessen, G., de Vries, E., van Hagen, P. M., Hartmann, I., Fraioli, F., Milito, C., Mitrevski, M., Quinti, I., Serra, G., Kelleher, P., Loebinger, M., Litzman, J., Postranecka, V., Thon, V., Babar, J., Condliffe, A. M., Exley, A., Kumararatne, D., Screaton, N., Jones, A., Bondioni, M. P., Lougaris, V., Plebani, A., Soresina, A., Sirignano, C., Spadaro, G., Galal, N., Gonzalez-Granado, L. I., Dettmer, S., Stirling, R., Chapel, H., Lucas, M., Patel, S., Farber, C. M., Meyts, I., Banerjee, A. K., Hackett, S., Hurst, J. R., Warnatz, K., Gathmann, B., Weidemann, J., Berthold, D., Baumann, U. (2019). Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. Journal of clinical immunology, 39(2), 225-227. https://doi.org/10.1007/s10875-019-00609-4
Schütz, Katharina, et al. "Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group." Journal of clinical immunology vol. 39,2 (2019): 225-227. doi: https://doi.org/10.1007/s10875-019-00609-4
Schütz K, Alecsandru D, Grimbacher B, Haddock J, Bruining A, Driessen G, de Vries E, van Hagen PM, Hartmann I, Fraioli F, Milito C, Mitrevski M, Quinti I, Serra G, Kelleher P, Loebinger M, Litzman J, Postranecka V, Thon V, Babar J, Condliffe AM, Exley A, Kumararatne D, Screaton N, Jones A, Bondioni MP, Lougaris V, Plebani A, Soresina A, Sirignano C, Spadaro G, Galal N, Gonzalez-Granado LI, Dettmer S, Stirling R, Chapel H, Lucas M, Patel S, Farber CM, Meyts I, Banerjee AK, Hackett S, Hurst JR, Warnatz K, Gathmann B, Weidemann J, Berthold D, Baumann U. Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. J Clin Immunol. 2019 Feb;39(2):225-227. doi: 10.1007/s10875-019-00609-4. PMID: 30905051.
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Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation.

Angewandte Chemie (International ed. in English)

Wang H, Pesciaioli F, Oliveira JCA, Warratz S, Ackermann L.
PMID: 28985452
Angew Chem Int Ed Engl. 2017 Nov 20;56(47):15063-15067. doi: 10.1002/anie.201708271. Epub 2017 Oct 24.

Chemoselective hydroarylations were accomplished by a novel synergistic Brønsted acid/manganese(I)-catalyzed C-H activation manifold. Thus, alkynes bearing O-leaving groups could, for the first time, be employed for C-H alkenylations without concurrent β-O elimination, thereby setting the stage for versatile late-stage...

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Wang H, Pesciaioli F, Oliveira JCA, et al. Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation. Angew Chem Int Ed Engl. 2017;56(47):15063-15067doi: 10.1002/anie.201708271.
Wang, H., Pesciaioli, F., Oliveira, J. C. A., Warratz, S., & Ackermann, L. (2017). Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation. Angewandte Chemie (International ed. in English), 56(47), 15063-15067. https://doi.org/10.1002/anie.201708271
Wang, Hui, et al. "Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation." Angewandte Chemie (International ed. in English) vol. 56,47 (2017): 15063-15067. doi: https://doi.org/10.1002/anie.201708271
Wang H, Pesciaioli F, Oliveira JCA, Warratz S, Ackermann L. Synergistic Manganese(I) C-H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):15063-15067. doi: 10.1002/anie.201708271. Epub 2017 Oct 24. PMID: 28985452.
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N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries.

Journal of the American Chemical Society

Li J, Warratz S, Zell D, De Sarkar S, Ishikawa EE, Ackermann L.
PMID: 26418891
J Am Chem Soc. 2015 Nov 04;137(43):13894-901. doi: 10.1021/jacs.5b08435. Epub 2015 Oct 22.

Acylated amino acid ligands enabled ruthenium(II)-catalyzed C-H functionalizations with excellent levels of meta-selectivity. The outstanding catalytic activity of the ruthenium(II) complexes derived from monoprotected amino acids (MPAA) set the stage for the first ruthenium-catalyzed meta-functionalizations with removable directing groups....

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Li J, Warratz S, Zell D, et al. N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries. J Am Chem Soc. 2015;137(43):13894-901doi: 10.1021/jacs.5b08435.
Li, J., Warratz, S., Zell, D., De Sarkar, S., Ishikawa, E. E., & Ackermann, L. (2015). N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries. Journal of the American Chemical Society, 137(43), 13894-901. https://doi.org/10.1021/jacs.5b08435
Li, Jie, et al. "N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries." Journal of the American Chemical Society vol. 137,43 (2015): 13894-901. doi: https://doi.org/10.1021/jacs.5b08435
Li J, Warratz S, Zell D, De Sarkar S, Ishikawa EE, Ackermann L. N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C-H tert-Alkylation with Removable Auxiliaries. J Am Chem Soc. 2015 Nov 04;137(43):13894-901. doi: 10.1021/jacs.5b08435. Epub 2015 Oct 22. PMID: 26418891.
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Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity.

The Journal of allergy and clinical immunology

Haimel M, Pazmandi J, Heredia RJ, Dmytrus J, Bal SK, Zoghi S, van Daele P, Briggs TA, Wouters C, Bader-Meunier B, Aeschlimann FA, Caorsi R, Eleftheriou D, Hoppenreijs E, Salzer E, Bakhtiar S, Derfalvi B, Saettini F, Kusters MAA, Elfeky R, Trück J, Rivière JG, van der Burg M, Gattorno M, Seidel MG, Burns S, Warnatz K, Hauck F, Brogan P, Gilmour KC, Schuetz C, Simon A, Bock C, Hambleton S, de Vries E, Robinson PN, van Gijn M, Boztug K.
PMID: 33991581
J Allergy Clin Immunol. 2021 May 12; doi: 10.1016/j.jaci.2021.04.033. Epub 2021 May 12.

BACKGROUND: Accurate, detailed, and standardized phenotypic descriptions are essential to support diagnostic interpretation of genetic variants and to discover new diseases. The Human Phenotype Ontology (HPO), extensively used in rare disease research, provides a rich collection of vocabulary with...

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Haimel M, Pazmandi J, Heredia RJ, et al. Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity. J Allergy Clin Immunol. 2021;doi: 10.1016/j.jaci.2021.04.033.
Haimel, M., Pazmandi, J., Heredia, R. J., Dmytrus, J., Bal, S. K., Zoghi, S., van Daele, P., Briggs, T. A., Wouters, C., Bader-Meunier, B., Aeschlimann, F. A., Caorsi, R., Eleftheriou, D., Hoppenreijs, E., Salzer, E., Bakhtiar, S., Derfalvi, B., Saettini, F., Kusters, M. A. A., Elfeky, R., Trück, J., Rivière, J. G., van der Burg, M., Gattorno, M., Seidel, M. G., Burns, S., Warnatz, K., Hauck, F., Brogan, P., Gilmour, K. C., Schuetz, C., Simon, A., Bock, C., Hambleton, S., de Vries, E., Robinson, P. N., van Gijn, M., & Boztug, K. (2021). Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity. The Journal of allergy and clinical immunology, . https://doi.org/10.1016/j.jaci.2021.04.033
Haimel, Matthias, et al. "Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity." The Journal of allergy and clinical immunology vol. (2021). doi: https://doi.org/10.1016/j.jaci.2021.04.033
Haimel M, Pazmandi J, Heredia RJ, Dmytrus J, Bal SK, Zoghi S, van Daele P, Briggs TA, Wouters C, Bader-Meunier B, Aeschlimann FA, Caorsi R, Eleftheriou D, Hoppenreijs E, Salzer E, Bakhtiar S, Derfalvi B, Saettini F, Kusters MAA, Elfeky R, Trück J, Rivière JG, van der Burg M, Gattorno M, Seidel MG, Burns S, Warnatz K, Hauck F, Brogan P, Gilmour KC, Schuetz C, Simon A, Bock C, Hambleton S, de Vries E, Robinson PN, van Gijn M, Boztug K. Curation and expansion of Human Phenotype Ontology for defined groups of inborn errors of immunity. J Allergy Clin Immunol. 2021 May 12; doi: 10.1016/j.jaci.2021.04.033. Epub 2021 May 12. PMID: 33991581.
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Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency.

Journal of clinical immunology

Lang-Meli J, Fuchs J, Mathé P, Ho HE, Kern L, Jaki L, Rusignuolo G, Mertins S, Somogyi V, Neumann-Haefelin C, Trinkmann F, Müller M, Thimme R, Umhau M, Quinti I, Wagner D, Panning M, Cunningham-Rundles C, Laubner K, Warnatz K.
PMID: 34893946
J Clin Immunol. 2021 Dec 10; doi: 10.1007/s10875-021-01193-2. Epub 2021 Dec 10.

Patients with primary antibody deficiency are at risk for severe and in many cases for prolonged COVID-19. Convalescent plasma treatment of immunocompromised individuals could be an option especially in countries with limited access to monoclonal antibody therapies. While studies...

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Lang-Meli J, Fuchs J, Mathé P, et al. Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. J Clin Immunol. 2021;doi: 10.1007/s10875-021-01193-2.
Lang-Meli, J., Fuchs, J., Mathé, P., Ho, H. E., Kern, L., Jaki, L., Rusignuolo, G., Mertins, S., Somogyi, V., Neumann-Haefelin, C., Trinkmann, F., Müller, M., Thimme, R., Umhau, M., Quinti, I., Wagner, D., Panning, M., Cunningham-Rundles, C., Laubner, K., & Warnatz, K. (2021). Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. Journal of clinical immunology, . https://doi.org/10.1007/s10875-021-01193-2
Lang-Meli, Julia, et al. "Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency." Journal of clinical immunology vol. (2021). doi: https://doi.org/10.1007/s10875-021-01193-2
Lang-Meli J, Fuchs J, Mathé P, Ho HE, Kern L, Jaki L, Rusignuolo G, Mertins S, Somogyi V, Neumann-Haefelin C, Trinkmann F, Müller M, Thimme R, Umhau M, Quinti I, Wagner D, Panning M, Cunningham-Rundles C, Laubner K, Warnatz K. Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. J Clin Immunol. 2021 Dec 10; doi: 10.1007/s10875-021-01193-2. Epub 2021 Dec 10. PMID: 34893946.
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Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity.

The Journal of allergy and clinical immunology

Groß M, Speckmann C, May A, Gajardo-Carrasco T, Wustrau K, Maier SL, Panning M, Huzly D, Agaimy A, Bryceson YT, Choo S, Chow CW, Dückers G, Fasth A, Fraitag S, Gräwe K, Haxelmans S, Holzinger D, Hudowenz O, Hübschen JM, Khurana C, Kienle K, Klifa R, Korn K, Kutzner H, Lämmermann T, Ledig S, Lipsker D, Meeths M, Naumann-Bartsch N, Rascon J, Schänzer A, Seidl M, Tesi B, Vauloup-Fellous C, Vollmer-Kary B, Warnatz K, Wehr C, Neven B, Vargas P, Sepulveda FE, Lehmberg K, Schmitt-Graeff A, Ehl S.
PMID: 34033843
J Allergy Clin Immunol. 2021 May 24; doi: 10.1016/j.jaci.2021.05.007. Epub 2021 May 24.

BACKGROUND: Rubella virus-induced granulomas have been described in patients with various inborn errors of immunity. Most defects impair T-cell immunity, suggesting a critical role of T cells in rubella elimination. However, the molecular mechanism of virus control remains elusive.OBJECTIVE:...

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Groß M, Speckmann C, May A, et al. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. J Allergy Clin Immunol. 2021;doi: 10.1016/j.jaci.2021.05.007.
Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A., & Ehl, S. (2021). Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The Journal of allergy and clinical immunology, . https://doi.org/10.1016/j.jaci.2021.05.007
Groß, Miriam, et al. "Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity." The Journal of allergy and clinical immunology vol. (2021). doi: https://doi.org/10.1016/j.jaci.2021.05.007
Groß M, Speckmann C, May A, Gajardo-Carrasco T, Wustrau K, Maier SL, Panning M, Huzly D, Agaimy A, Bryceson YT, Choo S, Chow CW, Dückers G, Fasth A, Fraitag S, Gräwe K, Haxelmans S, Holzinger D, Hudowenz O, Hübschen JM, Khurana C, Kienle K, Klifa R, Korn K, Kutzner H, Lämmermann T, Ledig S, Lipsker D, Meeths M, Naumann-Bartsch N, Rascon J, Schänzer A, Seidl M, Tesi B, Vauloup-Fellous C, Vollmer-Kary B, Warnatz K, Wehr C, Neven B, Vargas P, Sepulveda FE, Lehmberg K, Schmitt-Graeff A, Ehl S. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. J Allergy Clin Immunol. 2021 May 24; doi: 10.1016/j.jaci.2021.05.007. Epub 2021 May 24. PMID: 34033843.
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International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome.

The Journal of allergy and clinical immunology

Dimitrova D, Nademi Z, Maccari ME, Ehl S, Uzel G, Tomoda T, Okano T, Imai K, Carpenter B, Ip W, Rao K, Worth AJJ, Laberko A, Mukhina A, Néven B, Moshous D, Speckmann C, Warnatz K, Wehr C, Abolhassani H, Aghamohammadi A, Bleesing JJ, Dara J, Dvorak CC, Ghosh S, Kang HJ, Markelj G, Modi A, Bayer DK, Notarangelo LD, Schulz A, Garcia-Prat M, Soler-Palacín P, Karakükcü M, Yilmaz E, Gambineri E, Menconi M, Masmas TN, Holm M, Bonfim C, Prando C, Hughes S, Jolles S, Morris EC, Kapoor N, Koltan S, Paneesha S, Steward C, Wynn R, Duffner U, Gennery AR, Lankester AC, Slatter M, Kanakry JA.
PMID: 34033842
J Allergy Clin Immunol. 2022 Jan;149(1):410-421.e7. doi: 10.1016/j.jaci.2021.04.036. Epub 2021 May 24.

BACKGROUND: Activated phosphoinositide 3-kinase delta syndrome (APDS) is a combined immunodeficiency with a heterogeneous phenotype considered reversible by allogeneic hematopoietic cell transplantation (HCT).OBJECTIVES: This study sought to characterize HCT outcomes in APDS.METHODS: Retrospective data were collected on 57 patients...

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Dimitrova D, Nademi Z, Maccari ME, et al. International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. J Allergy Clin Immunol. 2021;149(1):410-421.e7doi: 10.1016/j.jaci.2021.04.036.
Dimitrova, D., Nademi, Z., Maccari, M. E., Ehl, S., Uzel, G., Tomoda, T., Okano, T., Imai, K., Carpenter, B., Ip, W., Rao, K., Worth, A. J. J., Laberko, A., Mukhina, A., Néven, B., Moshous, D., Speckmann, C., Warnatz, K., Wehr, C., Abolhassani, H., Aghamohammadi, A., Bleesing, J. J., Dara, J., Dvorak, C. C., Ghosh, S., Kang, H. J., Markelj, G., Modi, A., Bayer, D. K., Notarangelo, L. D., Schulz, A., Garcia-Prat, M., Soler-Palacín, P., Karakükcü, M., Yilmaz, E., Gambineri, E., Menconi, M., Masmas, T. N., Holm, M., Bonfim, C., Prando, C., Hughes, S., Jolles, S., Morris, E. C., Kapoor, N., Koltan, S., Paneesha, S., Steward, C., Wynn, R., Duffner, U., Gennery, A. R., Lankester, A. C., Slatter, M., & Kanakry, J. A. (2022). International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. The Journal of allergy and clinical immunology, 149(1), 410-421.e7. https://doi.org/10.1016/j.jaci.2021.04.036
Dimitrova, Dimana, et al. "International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome." The Journal of allergy and clinical immunology vol. 149,1 (2022): 410-421.e7. doi: https://doi.org/10.1016/j.jaci.2021.04.036
Dimitrova D, Nademi Z, Maccari ME, Ehl S, Uzel G, Tomoda T, Okano T, Imai K, Carpenter B, Ip W, Rao K, Worth AJJ, Laberko A, Mukhina A, Néven B, Moshous D, Speckmann C, Warnatz K, Wehr C, Abolhassani H, Aghamohammadi A, Bleesing JJ, Dara J, Dvorak CC, Ghosh S, Kang HJ, Markelj G, Modi A, Bayer DK, Notarangelo LD, Schulz A, Garcia-Prat M, Soler-Palacín P, Karakükcü M, Yilmaz E, Gambineri E, Menconi M, Masmas TN, Holm M, Bonfim C, Prando C, Hughes S, Jolles S, Morris EC, Kapoor N, Koltan S, Paneesha S, Steward C, Wynn R, Duffner U, Gennery AR, Lankester AC, Slatter M, Kanakry JA. International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. J Allergy Clin Immunol. 2022 Jan;149(1):410-421.e7. doi: 10.1016/j.jaci.2021.04.036. Epub 2021 May 24. PMID: 34033842; PMCID: PMC8611111.
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Editorial: Interstitial Lung Disease in Primary Immunodeficiencies.

Frontiers in immunology

Fevang B, Warnatz K, Hurst JR.
PMID: 34305936
Front Immunol. 2021 Jul 08;12:699126. doi: 10.3389/fimmu.2021.699126. eCollection 2021.

No abstract available.

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Fevang B, Warnatz K, Hurst JR. Editorial: Interstitial Lung Disease in Primary Immunodeficiencies. Front Immunol. 2021;12:699126doi: 10.3389/fimmu.2021.699126.
Fevang, B., Warnatz, K., & Hurst, J. R. (2021). Editorial: Interstitial Lung Disease in Primary Immunodeficiencies. Frontiers in immunology, 12699126. https://doi.org/10.3389/fimmu.2021.699126
Fevang, Børre, et al. "Editorial: Interstitial Lung Disease in Primary Immunodeficiencies." Frontiers in immunology vol. 12 (2021): 699126. doi: https://doi.org/10.3389/fimmu.2021.699126
Fevang B, Warnatz K, Hurst JR. Editorial: Interstitial Lung Disease in Primary Immunodeficiencies. Front Immunol. 2021 Jul 08;12:699126. doi: 10.3389/fimmu.2021.699126. eCollection 2021. PMID: 34305936; PMCID: PMC8296640.
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Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency.

Journal of clinical immunology

Lang-Meli J, Fuchs J, Mathé P, Ho HE, Kern L, Jaki L, Rusignuolo G, Mertins S, Somogyi V, Neumann-Haefelin C, Trinkmann F, Müller M, Thimme R, Umhau M, Quinti I, Wagner D, Panning M, Cunningham-Rundles C, Laubner K, Warnatz K.
PMID: 34893946
J Clin Immunol. 2021 Dec 10; doi: 10.1007/s10875-021-01193-2. Epub 2021 Dec 10.

Patients with primary antibody deficiency are at risk for severe and in many cases for prolonged COVID-19. Convalescent plasma treatment of immunocompromised individuals could be an option especially in countries with limited access to monoclonal antibody therapies. While studies...

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Lang-Meli J, Fuchs J, Mathé P, et al. Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. J Clin Immunol. 2021;doi: 10.1007/s10875-021-01193-2.
Lang-Meli, J., Fuchs, J., Mathé, P., Ho, H. E., Kern, L., Jaki, L., Rusignuolo, G., Mertins, S., Somogyi, V., Neumann-Haefelin, C., Trinkmann, F., Müller, M., Thimme, R., Umhau, M., Quinti, I., Wagner, D., Panning, M., Cunningham-Rundles, C., Laubner, K., & Warnatz, K. (2021). Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. Journal of clinical immunology, . https://doi.org/10.1007/s10875-021-01193-2
Lang-Meli, Julia, et al. "Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency." Journal of clinical immunology vol. (2021). doi: https://doi.org/10.1007/s10875-021-01193-2
Lang-Meli J, Fuchs J, Mathé P, Ho HE, Kern L, Jaki L, Rusignuolo G, Mertins S, Somogyi V, Neumann-Haefelin C, Trinkmann F, Müller M, Thimme R, Umhau M, Quinti I, Wagner D, Panning M, Cunningham-Rundles C, Laubner K, Warnatz K. Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency. J Clin Immunol. 2021 Dec 10; doi: 10.1007/s10875-021-01193-2. Epub 2021 Dec 10. PMID: 34893946; PMCID: PMC8664001.
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