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Showing 13 to 24 of 54 entries
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Mapping metabolic oscillations during cell cycle progression.

Cell cycle (Georgetown, Tex.)

Roci I, Watrous JD, Lagerborg KA, Jain M, Nilsson R.
PMID: 33016215
Cell Cycle. 2020 Oct;19(20):2676-2684. doi: 10.1080/15384101.2020.1825203. Epub 2020 Oct 04.

Proliferating cells must synthesize a wide variety of macromolecules while progressing through the cell cycle, but the coordination between cell cycle progression and cellular metabolism is still poorly understood. To identify metabolic processes that oscillate over the cell cycle,...

The relationship between self-reported physical functioning, mental health, and quality of life in Service members after combat-related lower extremity amputation.

Disability and rehabilitation

Eskridge SL, Watrous JR, McCabe CT, Clouser MC, Galarneau MR.
PMID: 33355027
Disabil Rehabil. 2020 Dec 23;1-7. doi: 10.1080/09638288.2020.1863481. Epub 2020 Dec 23.

PURPOSE: Service members with amputations experience numerous challenges, yet few studies have examined patient-reported outcomes, including physical functional status, mental-health screening status, and quality of life (QOL) or the relationship between these outcomes.MATERIALS AND METHODS: Service members with combat-related...

Population pharmacokinetics of pomalidomide in patients with relapsed or refractory multiple myeloma with various degrees of impaired renal function.

Clinical pharmacology : advances and applications

Li Y, Wang X, O'Mara E, Dimopoulos MA, Sonneveld P, Weisel KC, Matous J, Siegel DS, Shah JJ, Kueenburg E, Sternas L, Cavanaugh C, Zaki M, Palmisano M, Zhou S.
PMID: 29184451
Clin Pharmacol. 2017 Nov 08;9:133-145. doi: 10.2147/CPAA.S144606. eCollection 2017.

Pomalidomide is an immunomodulatory drug for treatment of relapsed or refractory multiple myeloma (rrMM) in patients who often have comorbid renal conditions. To assess the impact of renal impairment on pomalidomide exposure, a population pharmacokinetics (PPK) model of pomalidomide...

A Single Visualization Technique for Displaying Multiple Metabolite-Phenotype Associations.

Metabolites

Henglin M, Niiranen T, Watrous JD, Lagerborg KA, Antonelli J, Claggett BL, Demosthenes EJ, von Jeinsen B, Demler O, Vasan RS, Larson MG, Jain M, Cheng S.
PMID: 31269707
Metabolites. 2019 Jul 02;9(7). doi: 10.3390/metabo9070128.

To assist with management and interpretation of human metabolomics data, which are rapidly increasing in quantity and complexity, we need better visualization tools. Using a dataset of several hundred metabolite measures profiled in a cohort of ~1500 individuals sampled...

Diet and nutritional status during early adult life have immediate and persistent effects on queen bumble bees.

Conservation physiology

Woodard SH, Duennes MA, Watrous KM, Jha S.
PMID: 32802333
Conserv Physiol. 2019 Aug 15;7(1):coz048. doi: 10.1093/conphys/coz048. eCollection 2019.

Many insects sequester nutrients during developmentally programmed periods, which they metabolize during subsequent life history stages. During these periods, failure to store adequate nutrients can have persistent effects on fitness. Here, we examined a critical but under-studied nutrient storage...

Revisiting the simulation of quantum Turing machines by quantum circuits.

Proceedings. Mathematical, physical, and engineering sciences

Molina A, Watrous J.
PMID: 31293355
Proc Math Phys Eng Sci. 2019 Jun;475(2226):20180767. doi: 10.1098/rspa.2018.0767. Epub 2019 Jun 12.

Yao's 1995 publication 'Quantum circuit complexity' in

The spectro-contextual encoding and retrieval theory of episodic memory.

Frontiers in human neuroscience

Watrous AJ, Ekstrom AD.
PMID: 24600373
Front Hum Neurosci. 2014 Feb 18;8:75. doi: 10.3389/fnhum.2014.00075. eCollection 2014.

The spectral fingerprint hypothesis, which posits that different frequencies of oscillations underlie different cognitive operations, provides one account for how interactions between brain regions support perceptual and attentive processes (Siegel etal., 2012). Here, we explore and extend this idea...

A Web Service Framework for Interactive Analysis of Metabolomics Data.

Analytical chemistry

Lyutvinskiy Y, Watrous JD, Jain M, Nilsson R.
PMID: 28514166
Anal Chem. 2017 Jun 06;89(11):5713-5718. doi: 10.1021/acs.analchem.7b00890. Epub 2017 May 17.

Analyzing mass spectrometry-based metabolomics data presents a major challenge to metabolism researchers, as it requires downloading and processing large data volumes through complex "pipelines", even in cases where only a single metabolite or peak is of interest. This presents...

Is Lactic Acid Related to Delayed-Onset Muscle Soreness?.

The Physician and sportsmedicine

Schwane JA, Watrous BG, Johnson SR, Armstrong RB.
PMID: 27409551
Phys Sportsmed. 1983 Mar;11(3):124-31. doi: 10.1080/00913847.1983.11708485.

In brief: The authors tested the hypothesis that delayed-onset muscular soreness after running is related to the production of lactic acid during the exercise. Blood lactic acid concentration was measured before and during 45 minutes of treadmill running, one...

Persistent Opioid Use After Combat Injury and Subsequent Long-term Risk of Abuse: A Retrospective Cohort Study.

Annals of surgery

Beyer CA, Poltavskiy E, Walker LE, Pettey W, Suo Y, Redd A, Rittel AG, Kazanis WH, Dunham JR, Zarzabal LA, Rutter WC, Sim A, Watrous JR, Howard JT, Janak JC, Stewart IJ, Gundlapalli A.
PMID: 31714315
Ann Surg. 2021 Dec 01;274(6):e957-e965. doi: 10.1097/SLA.0000000000003658.

OBJECTIVE: To determine whether persistent opioid use after injury is associated with subsequent long-term development of clinically recognized opioid abuse.SUMMARY BACKGROUND DATA: Opioid abuse is an epidemic in the United States and trauma can initiate persistent use; however, it...

Postobstructive pulmonary edema: A fatal complication in suicidal near-hanging.

SAGE open medical case reports

Mesrati MA, Jaoued O, Mahjoub Y, Boussaid M, Fkih Hassen M, Atrous S, Aissaoui A.
PMID: 32547757
SAGE Open Med Case Rep. 2020 May 20;8:2050313X20922712. doi: 10.1177/2050313X20922712. eCollection 2020.

Postobstructive pulmonary edema is a life-threatening complication that occurs after the removal of severe upper airway obstruction. Development of postobstructive pulmonary edema has been described after several cases of upper airway obstruction. However, postobstructive pulmonary edema developing after non-lethal...

Multi-scale neural decoding and analysis.

Journal of neural engineering

Lu HY, Lorenc ES, Zhu H, Kilmarx J, Sulzer J, Xie C, Tobler PN, Watrous AJ, Orsborn AL, Lewis-Peacock J, Santacruz SR.
PMID: 34284369
J Neural Eng. 2021 Aug 16;18(4). doi: 10.1088/1741-2552/ac160f.

No abstract available.

Showing 13 to 24 of 54 entries