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Showing 145 to 152 of 152 entries
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Associations Between Fine Particulate Matter (PM2.5) and Childhood-Onset Systemic Lupus Erythematosus.

Indian journal of pediatrics

Mai CH, Shih YJ, Lin CL, Wei CC.
PMID: 34792746
Indian J Pediatr. 2022 Feb;89(2):200. doi: 10.1007/s12098-021-04006-x. Epub 2021 Nov 18.

No abstract available.

High-Fiber, Whole-Food Dietary Intervention Alters the Human Gut Microbiome but Not Fecal Short-Chain Fatty Acids.

mSystems

Oliver A, Chase AB, Weihe C, Orchanian SB, Riedel SF, Hendrickson CL, Lay M, Sewall JM, Martiny JBH, Whiteson K.
PMID: 33727392
mSystems. 2021 Mar 16;6(2). doi: 10.1128/mSystems.00115-21.

Dietary shifts can have a direct impact on the gut microbiome by preferentially selecting for microbes capable of utilizing the various dietary nutrients. The intake of dietary fiber has decreased precipitously in the last century, while consumption of processed...

High-entropy chaos generation using semiconductor lasers subject to intensity-modulated optical injection for certified physical random number generation.

Optics letters

Tseng CH, Funabashi R, Kanno K, Uchida A, Wei CC, Hwang SK.
PMID: 34264219
Opt Lett. 2021 Jul 15;46(14):3384-3387. doi: 10.1364/OL.431054.

This study investigates high-entropy chaos generation using a semiconductor laser subject to intensity-modulated optical injection for certified physical random number generation. Chaos with a continuous spectral profile that is not only widely distributed but also broadly flattened over a...

Neuronal VCP loss of function recapitulates FTLD-TDP pathology.

Cell reports

Wani A, Zhu J, Ulrich JD, Eteleeb A, Sauerbeck AD, Reitz SJ, Arhzaouy K, Ikenaga C, Yuede CM, Pittman SK, Wang F, Li S, Benitez BA, Cruchaga C, Kummer TT, Harari O, Chou TF, Schröder R, Clemen CS, Weihl CC.
PMID: 34289347
Cell Rep. 2021 Jul 20;36(3):109399. doi: 10.1016/j.celrep.2021.109399.

The pathogenic mechanism by which dominant mutations in VCP cause multisystem proteinopathy (MSP), a rare neurodegenerative disease that presents as fronto-temporal lobar degeneration with TDP-43 inclusions (FTLD-TDP), remains unclear. To explore this, we inactivate VCP in murine postnatal forebrain...

Risk factors of vesicoureteral reflux and urinary tract infections in children with imperforate anus: A population-based case-control study in Taiwan.

Medicine

Wu CW, Wei CC, Lin CL, Chao HH, Wei TC, Hsieh TH, Lin CY.
PMID: 34871211
Medicine (Baltimore). 2021 Nov 05;100(44):e27499. doi: 10.1097/MD.0000000000027499.

ABSTRACT: Imperforate anus (IA) is associated with several urological anomalies, including vesicoureteral reflux (VUR), a major contributor to high morbidity in patients with anorectal malformations. This retrospective study was performed to elucidate the risk factors of vesicoureteral reflux (VUR)...

Loss-of-function mutation in VCP mimics the characteristic pathology as in FTLD-TARDBP.

Autophagy

Wani A, Weihl CC.
PMID: 34632910
Autophagy. 2021 Dec;17(12):4502-4503. doi: 10.1080/15548627.2021.1985880. Epub 2021 Oct 10.

VCP (valosin containing protein), a member of the AAA+ protein family, is critical for many cellular processes and functions. Dominant VCP mutations cause a rare neurodegenerative disease known as multisystem proteinopathy (MSP). The spectrum of mechanisms causing fronto-temporal dementia...

mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants.

Immunity

Sokal A, Barba-Spaeth G, Fernández I, Broketa M, Azzaoui I, de La Selle A, Vandenberghe A, Fourati S, Roeser A, Meola A, Bouvier-Alias M, Crickx E, Languille L, Michel M, Godeau B, Gallien S, Melica G, Nguyen Y, Zarrouk V, Canoui-Poitrine F, Pirenne F, Mégret J, Pawlotsky JM, Fillatreau S, Bruhns P, Rey FA, Weill JC, Reynaud CA, Chappert P, Mahévas M.
PMID: 34614412
Immunity. 2021 Sep 21; doi: 10.1016/j.immuni.2021.09.011. Epub 2021 Sep 21.

In addition to serum immunoglobulins, memory B cell (MBC) generation against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune protection, but the quality of MBC responses in naive and coronavirus disease 2019 (COVID-19)-recovered individuals after...

Neuronal VCP loss of function recapitulates FTLD-TDP pathology.

Cell reports

Wani A, Zhu J, Ulrich JD, Eteleeb A, Sauerbeck AD, Reitz SJ, Arhzaouy K, Ikenaga C, Yuede CM, Pittman SK, Wang F, Li S, Benitez BA, Cruchaga C, Kummer TT, Harari O, Chou TF, Schröder R, Clemen CS, Weihl CC, McLean R.
PMID: 34289347
Cell Rep. 2021 Jul 20;36(3):109399. doi: 10.1016/j.celrep.2021.109399.

The pathogenic mechanism by which dominant mutations in VCP cause multisystem proteinopathy (MSP), a rare neurodegenerative disease that presents as fronto-temporal lobar degeneration with TDP-43 inclusions (FTLD-TDP), remains unclear. To explore this, we inactivate VCP in murine postnatal forebrain...

Showing 145 to 152 of 152 entries