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Showing 13 to 24 of 551 entries
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Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of .

Oncotarget

West MD, Labat I, Sternberg H, Larocca D, Nasonkin I, Chapman KB, Singh R, Makarev E, Aliper A, Kazennov A, Alekseenko A, Shuvalov N, Cheskidova E, Alekseev A, Artemov A, Putin E, Mamoshina P, Pryanichnikov N, Larocca J, Copeland K, Izumchenko E, Korzinkin M, Zhavoronkov A.
PMID: 29487692
Oncotarget. 2017 Dec 28;9(8):7796-7811. doi: 10.18632/oncotarget.23748. eCollection 2018 Jan 30.

Here we present the application of deep neural network (DNN) ensembles trained on transcriptomic data to identify the novel markers associated with the mammalian embryonic-fetal transition (EFT). Molecular markers of this process could provide important insights into regulatory mechanisms...

Early Implementation of THAM for ICP Control: Therapeutic Hypothermia Avoidance and Reduction in Hypertonics/Hyperosmotics.

Case reports in critical care

Zeiler FA, Gillman LM, Teitelbaum J, West M.
PMID: 25544901
Case Rep Crit Care. 2014;2014:139342. doi: 10.1155/2014/139342. Epub 2014 Dec 04.

Background. Tromethamine (THAM) has been demonstrated to reduce intracranial pressure (ICP). Early consideration for THAM may reduce the need for other measures for ICP control. Objective. To describe 4 cases of early THAM therapy for ICP control and highlight...

Editorial.

Environmental monitoring and assessment

Best EP, Haeck J.
PMID: 24259083
Environ Monit Assess. 1983 Sep;3(3):205. doi: 10.1007/BF00396212.

No abstract available.

New onset epilepsy following unintentional durotomy in a patient on anti-psychiatric medication.

Journal of surgical case reports

West M, Prasad P, Ampat G.
PMID: 24945984
J Surg Case Rep. 2010 Apr 01;2010(2):3. doi: 10.1093/jscr/2010.2.3.

We would like to present a rare case report describing a case in which new-onset tonic-clonic seizures occurred following an unintentional durotomy during lumbar discectomy and decompression. Unintentional durotomy is a frequent complication of spinal surgical procedures, with a...

Automatically Recognizing Medication and Adverse Event Information From Food and Drug Administration's Adverse Event Reporting System Narratives.

JMIR medical informatics

Polepalli Ramesh B, Belknap SM, Li Z, Frid N, West DP, Yu H.
PMID: 25600332
JMIR Med Inform. 2014 Jun 27;2(1):e10. doi: 10.2196/medinform.3022.

BACKGROUND: The Food and Drug Administration's (FDA) Adverse Event Reporting System (FAERS) is a repository of spontaneously-reported adverse drug events (ADEs) for FDA-approved prescription drugs. FAERS reports include both structured reports and unstructured narratives. The narratives often include essential...

Audit of the effectiveness of the nutrition team.

Clinical nutrition ESPEN

Youngman R, Patel M, West P, Eke M, Bhome G.
PMID: 28531513
Clin Nutr ESPEN. 2015 Oct;10(5):e195-e196. doi: 10.1016/j.clnesp.2015.03.044. Epub 2015 Aug 28.

No abstract available.

Single-Molecule Surface-Enhanced Raman Scattering: Can STEM/EELS Image Electromagnetic Hot Spots?.

The journal of physical chemistry letters

Mirsaleh-Kohan N, Iberi V, Simmons PD, Bigelow NW, Vaschillo A, Rowland MM, Best MD, Pennycook SJ, Masiello DJ, Guiton BS, Camden JP.
PMID: 26295787
J Phys Chem Lett. 2012 Aug 16;3(16):2303-9. doi: 10.1021/jz300967q. Epub 2012 Aug 07.

Since the observation of single-molecule surface-enhanced Raman scattering (SMSERS) in 1997, questions regarding the nature of the electromagnetic hot spots responsible for such observations still persist. For the first time, we employ electron-energy-loss spectroscopy (EELS) in a scanning transmission...

Percutaneous native renal biopsy adequacy: a successful interdepartmental quality improvement activity.

Canadian journal of kidney health and disease

Geldenhuys L, Nicholson P, Sinha N, Dini A, Doucette S, Alfaadhel T, Keough V, West M.
PMID: 27408754
Can J Kidney Health Dis. 2015 Mar 13;2:8. doi: 10.1186/s40697-015-0043-z. eCollection 2015.

BACKGROUND: An adequate renal biopsy is essential for diagnosis and treatment of medical renal disease.OBJECTIVE: We evaluated two initiatives to improve adequacy of renal biopsy samples at our centre.DESIGN: Retrospective determination of renal biopsy adequacy.SETTING: Queen Elizabeth II Health...

Data Quality Monitoring in Clinical Trials: Has It Been Worth It? An Evaluation and Prediction of the Future by All Stakeholders.

Innovations in clinical neuroscience

, Daniel D, Kalali A, West M, Walling D, Hilt D, Engelhardt N, Alphs L, Loebel A, Vanover K, Atkinson S, Opler M, Sachs G, Nations K, Brady C.
PMID: 27413584
Innov Clin Neurosci. 2016 Feb 01;13(1):27-33. eCollection 2016.

This paper summarizes the results of the CNS Summit Data Quality Monitoring Workgroup analysis of current data quality monitoring techniques used in central nervous system (CNS) clinical trials. Based on audience polls conducted at the CNS Summit 2014, the...

Vertical saccade palsy: a presenting sign of Niemann-Pick type IIS.

European journal of neurology

Shawkat FS, Carr L, West P, Taylor DS, Surtees R, Harris CM.
PMID: 24283435
Eur J Neurol. 1994 Sep;1(1):93-5. doi: 10.1111/j.1468-1331.1994.tb00056.x.

An 8 year old sister of a patient undergoing investigations for Niemann-Pick type IIS was observed to have mild difficulties in making downward saccades. She had no other symptoms apart from longstanding mild learning difficulties. Detailed eye movement assessment,...

Pediatric traumatic brain injuries treated with decompressive craniectomy.

Surgical neurology international

Patel N, West M, Wurster J, Tillman C.
PMID: 24232244
Surg Neurol Int. 2013 Sep 27;4:128. doi: 10.4103/2152-7806.119055. eCollection 2013.

BACKGROUND: Traumatic brain injury (TBI) occurs in an estimated 80% of all pediatric trauma patients and is the leading cause of death and disability in the pediatric population. Decompressive craniectomy is a procedure used to decrease intracranial pressure by...

High-accuracy X-ray absorption spectra from mM solutions of nickel (II) complexes with multiple solutions using transmission XAS.

Journal of synchrotron radiation

Chantler CT, Islam MT, Best SP, Tantau LJ, Tran CQ, Cheah MH, Payne AT.
PMID: 26134805
J Synchrotron Radiat. 2015 Jul;22(4):1008-21. doi: 10.1107/S1600577515006190. Epub 2015 Jun 19.

A new approach is introduced for determining X-ray absorption spectroscopy (XAS) spectra on absolute and relative scales using multiple solutions with different concentrations by the characterization and correction of experimental systematics. This hybrid technique is a development of standard...

Showing 13 to 24 of 551 entries