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Showing 349 to 351 of 351 entries
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Phospho-regulated Bim1/EB1 interactions trigger Dam1c ring assembly at the budding yeast outer kinetochore.

The EMBO journal

Dudziak A, Engelhard L, Bourque C, Klink BU, Rombaut P, Kornakov N, Jänen K, Herzog F, Gatsogiannis C, Westermann S.
PMID: 34313341
EMBO J. 2021 Sep 15;40(18):e108004. doi: 10.15252/embj.2021108004. Epub 2021 Jul 27.

Kinetochores form the link between chromosomes and microtubules of the mitotic spindle. The heterodecameric Dam1 complex (Dam1c) is a major component of the Saccharomyces cerevisiae outer kinetochore, assembling into 3 MDa-sized microtubule-embracing rings, but how ring assembly is specifically...

The association of anaemia and high-sensitivity cardiac troponin and its effect on diagnosing myocardial infarction.

European heart journal. Acute cardiovascular care

Haller PM, Neumann JT, Sörensen NA, Hartikainen TS, Goßling A, Lehmacher J, Keller T, Zeller T, Blankenberg S, Westermann D.
PMID: 34350455
Eur Heart J Acute Cardiovasc Care. 2021 Dec 18;10(10):1187-1196. doi: 10.1093/ehjacc/zuab066.

AIMS: Anaemia is common in patients with acute myocardial infarction (MI). We investigated the association of high-sensitivity cardiac troponin (hs-cTn) and haemoglobin (Hb) and the influence of anaemia on the performance of diagnostic protocols for suspected MI.METHODS AND RESULTS:...

Precision medicine in myeloid malignancies.

Seminars in cancer biology

Westermann J, Bullinger L, Koven MEJ.
PMID: 33895273
Semin Cancer Biol. 2021 Apr 22; doi: 10.1016/j.semcancer.2021.03.034. Epub 2021 Apr 22.

Myeloid malignancies have always been at the forefront of an improved understanding of the molecular pathogenesis of cancer. In accordance, over the last years, basic research focusing on the aberrations underlying malignant transformation of myeloid cells has provided the...

Showing 349 to 351 of 351 entries