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Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.

Cell metabolism

Gruber T, Pan C, Contreras RE, Wiedemann T, Morgan DA, Skowronski AA, Lefort S, De Bernardis Murat C, Le Thuc O, Legutko B, Ruiz-Ojeda FJ, Fuente-Fernández M, García-Villalón AL, González-Hedström D, Huber M, Szigeti-Buck K, Müller TD, Ussar S, Pfluger P, Woods SC, Ertürk A, LeDuc CA, Rahmouni K, Granado M, Horvath TL, Tschöp MH, García-Cáceres C.
PMID: 33951475
Cell Metab. 2021 Jun 01;33(6):1155-1170.e10. doi: 10.1016/j.cmet.2021.04.007. Epub 2021 May 04.

Pathologies of the micro- and macrovascular systems are a hallmark of the metabolic syndrome, which can lead to chronically elevated blood pressure. However, the underlying pathomechanisms involved still need to be clarified. Here, we report that an obesity-associated increase...

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Gruber T, Pan C, Contreras RE, et al. Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell Metab. 2021;33(6):1155-1170.e10doi: 10.1016/j.cmet.2021.04.007.
Gruber, T., Pan, C., Contreras, R. E., Wiedemann, T., Morgan, D. A., Skowronski, A. A., Lefort, S., De Bernardis Murat, C., Le Thuc, O., Legutko, B., Ruiz-Ojeda, F. J., Fuente-Fernández, M., García-Villalón, A. L., González-Hedström, D., Huber, M., Szigeti-Buck, K., Müller, T. D., Ussar, S., Pfluger, P., Woods, S. C., Ertürk, A., LeDuc, C. A., Rahmouni, K., Granado, M., Horvath, T. L., Tschöp, M. H., & García-Cáceres, C. (2021). Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell metabolism, 33(6), 1155-1170.e10. https://doi.org/10.1016/j.cmet.2021.04.007
Gruber, Tim, et al. "Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension." Cell metabolism vol. 33,6 (2021): 1155-1170.e10. doi: https://doi.org/10.1016/j.cmet.2021.04.007
Gruber T, Pan C, Contreras RE, Wiedemann T, Morgan DA, Skowronski AA, Lefort S, De Bernardis Murat C, Le Thuc O, Legutko B, Ruiz-Ojeda FJ, Fuente-Fernández M, García-Villalón AL, González-Hedström D, Huber M, Szigeti-Buck K, Müller TD, Ussar S, Pfluger P, Woods SC, Ertürk A, LeDuc CA, Rahmouni K, Granado M, Horvath TL, Tschöp MH, García-Cáceres C. Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell Metab. 2021 Jun 01;33(6):1155-1170.e10. doi: 10.1016/j.cmet.2021.04.007. Epub 2021 May 04. PMID: 33951475; PMCID: PMC8183500.
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The HeartMate 6 and CardioMEMS for Fixed Pulmonary Hypertension.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Angleitner P, Schlöglhofer T, Wiedemann D, Riebandt J, Strassl A, Mascherbauer J, Kainz M, Laufer G, Zuckermann A, Zimpfer D.
PMID: 33989210
ASAIO J. 2021 May 12; doi: 10.1097/MAT.0000000000001480. Epub 2021 May 12.

Fixed pulmonary hypertension (FPH) is a contraindication for heart transplantation (HTX). However, this condition might be reversed by continuous left-ventricular unloading with a left-ventricular assist device. We present a case of apical hypertrophic cardiomyopathy with extensive left-ventricular endocardial calcification...

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Angleitner P, Schlöglhofer T, Wiedemann D, et al. The HeartMate 6 and CardioMEMS for Fixed Pulmonary Hypertension. ASAIO J. 2021;doi: 10.1097/MAT.0000000000001480.
Angleitner, P., Schlöglhofer, T., Wiedemann, D., Riebandt, J., Strassl, A., Mascherbauer, J., Kainz, M., Laufer, G., Zuckermann, A., & Zimpfer, D. (2021). The HeartMate 6 and CardioMEMS for Fixed Pulmonary Hypertension. ASAIO journal (American Society for Artificial Internal Organs : 1992), . https://doi.org/10.1097/MAT.0000000000001480
Angleitner, Philipp, et al. "The HeartMate 6 and CardioMEMS for Fixed Pulmonary Hypertension." ASAIO journal (American Society for Artificial Internal Organs : 1992) vol. (2021). doi: https://doi.org/10.1097/MAT.0000000000001480
Angleitner P, Schlöglhofer T, Wiedemann D, Riebandt J, Strassl A, Mascherbauer J, Kainz M, Laufer G, Zuckermann A, Zimpfer D. The HeartMate 6 and CardioMEMS for Fixed Pulmonary Hypertension. ASAIO J. 2021 May 12; doi: 10.1097/MAT.0000000000001480. Epub 2021 May 12. PMID: 33989210.
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Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature.

Artificial organs

Steurer LM, Schlager G, Sadeghi K, Golej J, Wiedemann D, Hermon M.
PMID: 34331775
Artif Organs. 2021 Dec;45(12):1582-1593. doi: 10.1111/aor.14047. Epub 2021 Aug 12.

Hemadsorption via the cytokine-adsorber CytoSorb (CytoSorbents Europe, Berlin, Germany) has successfully been used as an adjunctive method in adults, mainly for the purpose of immunomodulation under acute inflammatory conditions such as sepsis and cardiac surgery. In recent years, there...

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Steurer LM, Schlager G, Sadeghi K, et al. Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature. Artif Organs. 2021;45(12):1582-1593doi: 10.1111/aor.14047.
Steurer, L. M., Schlager, G., Sadeghi, K., Golej, J., Wiedemann, D., & Hermon, M. (2021). Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature. Artificial organs, 45(12), 1582-1593. https://doi.org/10.1111/aor.14047
Steurer, Lisa-Maria, et al. "Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature." Artificial organs vol. 45,12 (2021): 1582-1593. doi: https://doi.org/10.1111/aor.14047
Steurer LM, Schlager G, Sadeghi K, Golej J, Wiedemann D, Hermon M. Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature. Artif Organs. 2021 Dec;45(12):1582-1593. doi: 10.1111/aor.14047. Epub 2021 Aug 12. PMID: 34331775.
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"Sharing Success with Someone": Building therapeutic alliance in physiotherapist-delivered physical activity coaching for healthy aging.

Physiotherapy theory and practice

Haynes A, Sherrington C, Ramsay E, Kirkham C, Manning S, Wallbank G, Hassett L, Tiedemann A.
PMID: 34324406
Physiother Theory Pract. 2021 Jul 29;1-17. doi: 10.1080/09593985.2021.1946872. Epub 2021 Jul 29.

INTRODUCTION: Therapeutic alliance, a goal-orientated partnership between clients and practitioners, can enhance program engagement and adherence, and improve treatment outcomes and satisfaction.OBJECTIVES: To develop an empirical model that describes how therapeutic alliances can be operationalized in clinical and research...

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Haynes A, Sherrington C, Ramsay E, et al. "Sharing Success with Someone": Building therapeutic alliance in physiotherapist-delivered physical activity coaching for healthy aging. Physiother Theory Pract. 2021;1-17doi: 10.1080/09593985.2021.1946872.
Haynes, A., Sherrington, C., Ramsay, E., Kirkham, C., Manning, S., Wallbank, G., Hassett, L., & Tiedemann, A. (2021). "Sharing Success with Someone": Building therapeutic alliance in physiotherapist-delivered physical activity coaching for healthy aging. Physiotherapy theory and practice, 1-17. https://doi.org/10.1080/09593985.2021.1946872
Haynes, Abby, et al. ""Sharing Success with Someone": Building therapeutic alliance in physiotherapist-delivered physical activity coaching for healthy aging." Physiotherapy theory and practice vol. (2021): 1-17. doi: https://doi.org/10.1080/09593985.2021.1946872
Haynes A, Sherrington C, Ramsay E, Kirkham C, Manning S, Wallbank G, Hassett L, Tiedemann A. "Sharing Success with Someone": Building therapeutic alliance in physiotherapist-delivered physical activity coaching for healthy aging. Physiother Theory Pract. 2021 Jul 29;1-17. doi: 10.1080/09593985.2021.1946872. Epub 2021 Jul 29. PMID: 34324406.
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The Use of Music in the Treatment and Management of Serious Mental Illness: A Global Scoping Review of the Literature.

Frontiers in psychology

Golden TL, Springs S, Kimmel HJ, Gupta S, Tiedemann A, Sandu CC, Magsamen S.
PMID: 33868127
Front Psychol. 2021 Mar 31;12:649840. doi: 10.3389/fpsyg.2021.649840. eCollection 2021.

Mental and substance use disorders have been identified as the leading cause of global disability, and the global burden of mental illness is concentrated among those experiencing disability due to serious mental illness (SMI). Music has been studied as...

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Golden TL, Springs S, Kimmel HJ, et al. The Use of Music in the Treatment and Management of Serious Mental Illness: A Global Scoping Review of the Literature. Front Psychol. 2021;12:649840doi: 10.3389/fpsyg.2021.649840.
Golden, T. L., Springs, S., Kimmel, H. J., Gupta, S., Tiedemann, A., Sandu, C. C., & Magsamen, S. (2021). The Use of Music in the Treatment and Management of Serious Mental Illness: A Global Scoping Review of the Literature. Frontiers in psychology, 12649840. https://doi.org/10.3389/fpsyg.2021.649840
Golden, Tasha L, et al. "The Use of Music in the Treatment and Management of Serious Mental Illness: A Global Scoping Review of the Literature." Frontiers in psychology vol. 12 (2021): 649840. doi: https://doi.org/10.3389/fpsyg.2021.649840
Golden TL, Springs S, Kimmel HJ, Gupta S, Tiedemann A, Sandu CC, Magsamen S. The Use of Music in the Treatment and Management of Serious Mental Illness: A Global Scoping Review of the Literature. Front Psychol. 2021 Mar 31;12:649840. doi: 10.3389/fpsyg.2021.649840. eCollection 2021. PMID: 33868127; PMCID: PMC8044514.
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Immune signature of multiple sclerosis-associated depression.

Brain, behavior, and immunity

Brasanac J, Ramien C, Gamradt S, Taenzer A, Glau L, Ritter K, Patas K, Agorastos A, Wiedemann K, Demiralay C, Fischer F, Otte C, Bellmann-Strobl J, Friese MA, Tolosa E, Paul F, Heesen C, Weygandt M, Gold SM.
PMID: 34863857
Brain Behav Immun. 2021 Dec 01;100:174-182. doi: 10.1016/j.bbi.2021.11.022. Epub 2021 Dec 01.

Multiple neurobiological pathways have been implicated in the pathobiology of major depressive disorder (MDD). The identification of reliable biological substrates across the entire MDD spectrum, however, is hampered by a vast heterogeneity in the clinical presentation, presumably as a...

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Brasanac J, Ramien C, Gamradt S, et al. Immune signature of multiple sclerosis-associated depression. Brain Behav Immun. 2021;100:174-182doi: 10.1016/j.bbi.2021.11.022.
Brasanac, J., Ramien, C., Gamradt, S., Taenzer, A., Glau, L., Ritter, K., Patas, K., Agorastos, A., Wiedemann, K., Demiralay, C., Fischer, F., Otte, C., Bellmann-Strobl, J., Friese, M. A., Tolosa, E., Paul, F., Heesen, C., Weygandt, M., & Gold, S. M. (2021). Immune signature of multiple sclerosis-associated depression. Brain, behavior, and immunity, 100174-182. https://doi.org/10.1016/j.bbi.2021.11.022
Brasanac, Jelena, et al. "Immune signature of multiple sclerosis-associated depression." Brain, behavior, and immunity vol. 100 (2021): 174-182. doi: https://doi.org/10.1016/j.bbi.2021.11.022
Brasanac J, Ramien C, Gamradt S, Taenzer A, Glau L, Ritter K, Patas K, Agorastos A, Wiedemann K, Demiralay C, Fischer F, Otte C, Bellmann-Strobl J, Friese MA, Tolosa E, Paul F, Heesen C, Weygandt M, Gold SM. Immune signature of multiple sclerosis-associated depression. Brain Behav Immun. 2021 Dec 01;100:174-182. doi: 10.1016/j.bbi.2021.11.022. Epub 2021 Dec 01. PMID: 34863857.
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The epidemiology of uveal melanoma in Germany: a nationwide report of incidence and survival between 2009 and 2015.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Alfaar AS, Saad A, Wiedemann P, Rehak M.
PMID: 34605956
Graefes Arch Clin Exp Ophthalmol. 2021 Oct 04; doi: 10.1007/s00417-021-05317-7. Epub 2021 Oct 04.

PURPOSE: To calculate the overall incidence of uveal melanoma in Germany and to compare incidences in different German states. In addition, we computed the overall and cancer-specific survival rates nationwide.METHODS: Incidence data for the period between 2009 and 2015,...

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Alfaar AS, Saad A, Wiedemann P, et al. The epidemiology of uveal melanoma in Germany: a nationwide report of incidence and survival between 2009 and 2015. Graefes Arch Clin Exp Ophthalmol. 2021;doi: 10.1007/s00417-021-05317-7.
Alfaar, A. S., Saad, A., Wiedemann, P., & Rehak, M. (2021). The epidemiology of uveal melanoma in Germany: a nationwide report of incidence and survival between 2009 and 2015. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, . https://doi.org/10.1007/s00417-021-05317-7
Alfaar, Ahmad Samir, et al. "The epidemiology of uveal melanoma in Germany: a nationwide report of incidence and survival between 2009 and 2015." Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie vol. (2021). doi: https://doi.org/10.1007/s00417-021-05317-7
Alfaar AS, Saad A, Wiedemann P, Rehak M. The epidemiology of uveal melanoma in Germany: a nationwide report of incidence and survival between 2009 and 2015. Graefes Arch Clin Exp Ophthalmol. 2021 Oct 04; doi: 10.1007/s00417-021-05317-7. Epub 2021 Oct 04. PMID: 34605956.
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[Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care].

Der Urologe. Ausg. A

Wiedemann A, Gedding C, Heese M, Stein J, Manseck A, Kirschner-Hermanns R, Karstedt H, Schorn A, Wagner A, Moll V, Unger U, Eisenhardt A, Bannowsky A, Linné C, Wirz S, Brammen E, Heppner HJ.
PMID: 34605933
Urologe A. 2021 Oct 04; doi: 10.1007/s00120-021-01642-1. Epub 2021 Oct 04.

BACKGROUND: The insertion of a Foley catheter (FC) or a suprapubic catheter (SPC) in lifelong intent is an intervention with significant complications, comorbidities and impact on the further life that has not yet been analyzed.METHODOLOGY: The analysis was based...

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Wiedemann A, Gedding C, Heese M, et al. Lebensqualität bei Trägern eines suprapubischen oder transurethralen Harnblasenkatheters als lebenslange Dauerversorgung. [Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care]. Urologe A. 2021;doi: 10.1007/s00120-021-01642-1.
Wiedemann, A., Gedding, C., Heese, M., Stein, J., Manseck, A., Kirschner-Hermanns, R., Karstedt, H., Schorn, A., Wagner, A., Moll, V., Unger, U., Eisenhardt, A., Bannowsky, A., Linné, C., Wirz, S., Brammen, E., & Heppner, H. J. (2021). Lebensqualität bei Trägern eines suprapubischen oder transurethralen Harnblasenkatheters als lebenslange Dauerversorgung. [Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care]. Der Urologe. Ausg. A, . https://doi.org/10.1007/s00120-021-01642-1
Wiedemann, A, et al. "Lebensqualität bei Trägern eines suprapubischen oder transurethralen Harnblasenkatheters als lebenslange Dauerversorgung." [Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care]. Der Urologe. Ausg. A vol. (2021). doi: https://doi.org/10.1007/s00120-021-01642-1
Wiedemann A, Gedding C, Heese M, Stein J, Manseck A, Kirschner-Hermanns R, Karstedt H, Schorn A, Wagner A, Moll V, Unger U, Eisenhardt A, Bannowsky A, Linné C, Wirz S, Brammen E, Heppner HJ. Lebensqualität bei Trägern eines suprapubischen oder transurethralen Harnblasenkatheters als lebenslange Dauerversorgung. [Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care]. Urologe A. 2021 Oct 04; doi: 10.1007/s00120-021-01642-1. Epub 2021 Oct 04. German. PMID: 34605933.
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Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing K.

International journal of biological macromolecules

Guzmán TJ, Düfer M, Wiedemann M, Olguín-Alor R, Soldevila G, Gurrola-Díaz CM.
PMID: 34280449
Int J Biol Macromol. 2021 Sep 30;187:76-90. doi: 10.1016/j.ijbiomac.2021.07.088. Epub 2021 Jul 17.

Lupin γ-conglutin beneficially modulates glycemia, but whether it protects against oxidative and lipotoxic damage remains unknown. Here, we studied the effects of γ-conglutin on cell death provoked by hydrogen peroxide and palmitate in HepG2 hepatocytes and insulin-producing MIN6 cells,...

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Guzmán TJ, Düfer M, Wiedemann M, et al. Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing K. Int J Biol Macromol. 2021;187:76-90doi: 10.1016/j.ijbiomac.2021.07.088.
Guzmán, T. J., Düfer, M., Wiedemann, M., Olguín-Alor, R., Soldevila, G., & Gurrola-Díaz, C. M. (2021). Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing K. International journal of biological macromolecules, 18776-90. https://doi.org/10.1016/j.ijbiomac.2021.07.088
Guzmán, Tereso J, et al. "Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing K." International journal of biological macromolecules vol. 187 (2021): 76-90. doi: https://doi.org/10.1016/j.ijbiomac.2021.07.088
Guzmán TJ, Düfer M, Wiedemann M, Olguín-Alor R, Soldevila G, Gurrola-Díaz CM. Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing K. Int J Biol Macromol. 2021 Sep 30;187:76-90. doi: 10.1016/j.ijbiomac.2021.07.088. Epub 2021 Jul 17. PMID: 34280449.
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Showing 529 to 537 of 537 entries