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Showing 265 to 274 of 274 entries
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Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer.

Molecular cancer therapeutics

Hu Y, Manasrah BK, McGregor SM, Lera RF, Norman RX, Tucker JB, Scribano CM, Yan RE, Humayun M, Wisinski KB, Tevaarwerk AJ, O'Regan RM, Wilke LG, Weaver BA, Beebe DJ, Jin N, Burkard ME.
PMID: 34583980
Mol Cancer Ther. 2021 Dec;20(12):2553-2567. doi: 10.1158/1535-7163.MCT-21-0195. Epub 2021 Sep 28.

Taxanes remain one of the most effective medical treatments for breast cancer. Clinical trials have coupled taxanes with immune checkpoint inhibitors in patients with triple-negative breast cancer (TNBC) with promising results. However, the mechanism linking taxanes to immune activation...

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Hu Y, Manasrah BK, McGregor SM, et al. Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer. Mol Cancer Ther. 2021;20(12):2553-2567doi: 10.1158/1535-7163.MCT-21-0195.
Hu, Y., Manasrah, B. K., McGregor, S. M., Lera, R. F., Norman, R. X., Tucker, J. B., Scribano, C. M., Yan, R. E., Humayun, M., Wisinski, K. B., Tevaarwerk, A. J., O'Regan, R. M., Wilke, L. G., Weaver, B. A., Beebe, D. J., Jin, N., & Burkard, M. E. (2021). Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer. Molecular cancer therapeutics, 20(12), 2553-2567. https://doi.org/10.1158/1535-7163.MCT-21-0195
Hu, Yang, et al. "Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer." Molecular cancer therapeutics vol. 20,12 (2021): 2553-2567. doi: https://doi.org/10.1158/1535-7163.MCT-21-0195
Hu Y, Manasrah BK, McGregor SM, Lera RF, Norman RX, Tucker JB, Scribano CM, Yan RE, Humayun M, Wisinski KB, Tevaarwerk AJ, O'Regan RM, Wilke LG, Weaver BA, Beebe DJ, Jin N, Burkard ME. Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer. Mol Cancer Ther. 2021 Dec;20(12):2553-2567. doi: 10.1158/1535-7163.MCT-21-0195. Epub 2021 Sep 28. PMID: 34583980; PMCID: PMC8643310.
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[No title available]

Medical mycology case reports

Teh JSK, Wilke AE, Overstall SM, Teng JC, Chin R, Couper JM, Lo CA, Waring LJ, Sheffield DA.
PMID: 34584835
Med Mycol Case Rep. 2021 Aug 18;34:22-26. doi: 10.1016/j.mmcr.2021.08.003. eCollection 2021 Dec.

We report the first published case of

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Teh JSK, Wilke AE, Overstall SM, et al. . Med Mycol Case Rep. 2021;34:22-26doi: 10.1016/j.mmcr.2021.08.003.
Teh, J. S. K., Wilke, A. E., Overstall, S. M., Teng, J. C., Chin, R., Couper, J. M., Lo, C. A., Waring, L. J., & Sheffield, D. A. (2021). . Medical mycology case reports, 3422-26. https://doi.org/10.1016/j.mmcr.2021.08.003
Teh, Joanne S K, et al. "." Medical mycology case reports vol. 34 (2021): 22-26. doi: https://doi.org/10.1016/j.mmcr.2021.08.003
Teh JSK, Wilke AE, Overstall SM, Teng JC, Chin R, Couper JM, Lo CA, Waring LJ, Sheffield DA. . Med Mycol Case Rep. 2021 Aug 18;34:22-26. doi: 10.1016/j.mmcr.2021.08.003. eCollection 2021 Dec. PMID: 34584835; PMCID: PMC8455647.
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Recent advances in fed-batch microscale bioreactor design.

Biotechnology advances

Teworte S, Malcı K, Walls LE, Halim M, Rios-Solis L.
PMID: 34923075
Biotechnol Adv. 2021 Dec 16;55:107888. doi: 10.1016/j.biotechadv.2021.107888. Epub 2021 Dec 16.

Advanced fed-batch microbioreactors mitigate scale up risks and more closely mimic industrial cultivation practices. Recently, high throughput microscale feeding strategies have been developed which improve the accessibility of microscale fed-batch cultivation irrespective of experimental budget. This review explores such...

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Teworte S, Malcı K, Walls LE, et al. Recent advances in fed-batch microscale bioreactor design. Biotechnol Adv. 2021;55:107888doi: 10.1016/j.biotechadv.2021.107888.
Teworte, S., Malcı, K., Walls, L. E., Halim, M., & Rios-Solis, L. (2021). Recent advances in fed-batch microscale bioreactor design. Biotechnology advances, 55107888. https://doi.org/10.1016/j.biotechadv.2021.107888
Teworte, Sarah, et al. "Recent advances in fed-batch microscale bioreactor design." Biotechnology advances vol. 55 (2021): 107888. doi: https://doi.org/10.1016/j.biotechadv.2021.107888
Teworte S, Malcı K, Walls LE, Halim M, Rios-Solis L. Recent advances in fed-batch microscale bioreactor design. Biotechnol Adv. 2021 Dec 16;55:107888. doi: 10.1016/j.biotechadv.2021.107888. Epub 2021 Dec 16. PMID: 34923075.
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Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis.

Movement disorders clinical practice

Lee W.
PMID: 33553491
Mov Disord Clin Pract. 2020 Sep 14;8(2):217-223. doi: 10.1002/mdc3.13070. eCollection 2021 Feb.

BACKGROUND: Numerous conventional magnetic resonance imaging (cMRI) parameters were previously found to differentiate parkinsonian disorders with statistical significance, but effect size has not been considered.OBJECTIVES: To quantify effect size of previously identified cMRI parameters that differentiated parkinsonian disorders with...

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Lee W. Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis. Mov Disord Clin Pract. 2020;8(2):217-223doi: 10.1002/mdc3.13070.
Lee, W. (2021). Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis. Movement disorders clinical practice, 8(2), 217-223. https://doi.org/10.1002/mdc3.13070
Lee, Will. "Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis." Movement disorders clinical practice vol. 8,2 (2021): 217-223. doi: https://doi.org/10.1002/mdc3.13070
Lee W. Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis. Mov Disord Clin Pract. 2020 Sep 14;8(2):217-223. doi: 10.1002/mdc3.13070. eCollection 2021 Feb. PMID: 33553491; PMCID: PMC7853196.
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Radiopaque drug-eluting embolisation beads as fiducial markers for stereotactic liver radiotherapy.

The British journal of radiology

Beaton L, Daly M, Tregidgo HF, Grimes H, Moinuddin S, Stacey C, Znati S, Hague J, Bascal ZA, Wilde PE, Cooper S, Bandula S, Lewis AL, Clarkson MJ, Sharma RA.
PMID: 34762499
Br J Radiol. 2021 Nov 16;20210594. doi: 10.1259/bjr.20210594. Epub 2021 Nov 16.

OBJECTIVE: To determine the feasibility of using radiopaque (RO) beads as direct tumour surrogates for image-guided radiotherapy (IGRT) in patients with liver tumours after transarterial chemoembolisation (TACE).METHODS: A novel vandetanib-eluting RO bead was delivered via TACE as part of...

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Beaton L, Daly M, Tregidgo HF, et al. Radiopaque drug-eluting embolisation beads as fiducial markers for stereotactic liver radiotherapy. Br J Radiol. 2021;20210594doi: 10.1259/bjr.20210594.
Beaton, L., Daly, M., Tregidgo, H. F., Grimes, H., Moinuddin, S., Stacey, C., Znati, S., Hague, J., Bascal, Z. A., Wilde, P. E., Cooper, S., Bandula, S., Lewis, A. L., Clarkson, M. J., & Sharma, R. A. (2021). Radiopaque drug-eluting embolisation beads as fiducial markers for stereotactic liver radiotherapy. The British journal of radiology, 20210594. https://doi.org/10.1259/bjr.20210594
Beaton, Laura, et al. "Radiopaque drug-eluting embolisation beads as fiducial markers for stereotactic liver radiotherapy." The British journal of radiology vol. (2021): 20210594. doi: https://doi.org/10.1259/bjr.20210594
Beaton L, Daly M, Tregidgo HF, Grimes H, Moinuddin S, Stacey C, Znati S, Hague J, Bascal ZA, Wilde PE, Cooper S, Bandula S, Lewis AL, Clarkson MJ, Sharma RA. Radiopaque drug-eluting embolisation beads as fiducial markers for stereotactic liver radiotherapy. Br J Radiol. 2021 Nov 16;20210594. doi: 10.1259/bjr.20210594. Epub 2021 Nov 16. PMID: 34762499.
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Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling.

Nature biomedical engineering

Wen S, Yin A, Furlanello T, Perich MG, Miller LE, Itti L.
PMID: 34795394
Nat Biomed Eng. 2021 Nov 18; doi: 10.1038/s41551-021-00811-z. Epub 2021 Nov 18.

For brain-computer interfaces (BCIs), obtaining sufficient training data for algorithms that map neural signals onto actions can be difficult, expensive or even impossible. Here we report the development and use of a generative model-a model that synthesizes a virtually...

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Wen S, Yin A, Furlanello T, et al. Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling. Nat Biomed Eng. 2021;doi: 10.1038/s41551-021-00811-z.
Wen, S., Yin, A., Furlanello, T., Perich, M. G., Miller, L. E., & Itti, L. (2021). Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling. Nature biomedical engineering, . https://doi.org/10.1038/s41551-021-00811-z
Wen, Shixian, et al. "Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling." Nature biomedical engineering vol. (2021). doi: https://doi.org/10.1038/s41551-021-00811-z
Wen S, Yin A, Furlanello T, Perich MG, Miller LE, Itti L. Rapid adaptation of brain-computer interfaces to new neuronal ensembles or participants via generative modelling. Nat Biomed Eng. 2021 Nov 18; doi: 10.1038/s41551-021-00811-z. Epub 2021 Nov 18. PMID: 34795394.
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Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Miller LE, Bhattacharyya N.
PMID: 33845681
Otolaryngol Head Neck Surg. 2021 Apr 13;1945998211006931. doi: 10.1177/01945998211006931. Epub 2021 Apr 13.

Chronic rhinosinusitis (CRS) management frequently comprises conservative treatment, including a combination of topical and oral corticosteroids (OCSs). However, in the midst of the coronavirus disease 2019 (COVID-19) pandemic, providers may have been reluctant to prescribe OCSs out of possible...

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Miller LE, Bhattacharyya N. Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids. Otolaryngol Head Neck Surg. 2021;1945998211006931doi: 10.1177/01945998211006931.
Miller, L. E., & Bhattacharyya, N. (2021). Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1945998211006931. https://doi.org/10.1177/01945998211006931
Miller, Lauren E, and Bhattacharyya, Neil. "Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery vol. (2021): 1945998211006931. doi: https://doi.org/10.1177/01945998211006931
Miller LE, Bhattacharyya N. Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids. Otolaryngol Head Neck Surg. 2021 Apr 13;1945998211006931. doi: 10.1177/01945998211006931. Epub 2021 Apr 13. PMID: 33845681.
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Recent advances in fed-batch microscale bioreactor design.

Biotechnology advances

Teworte S, Malcı K, Walls LE, Halim M, Rios-Solis L.
PMID: 34923075
Biotechnol Adv. 2021 Dec 16;107888. doi: 10.1016/j.biotechadv.2021.107888. Epub 2021 Dec 16.

Advanced fed-batch microbioreactors mitigate scale up risks and more closely mimic industrial cultivation practices. Recently, high throughput microscale feeding strategies have been developed which improve the accessibility of microscale fed-batch cultivation irrespective of experimental budget. This review explores such...

Cite
Teworte S, Malcı K, Walls LE, et al. Recent advances in fed-batch microscale bioreactor design. Biotechnol Adv. 2021;107888doi: 10.1016/j.biotechadv.2021.107888.
Teworte, S., Malcı, K., Walls, L. E., Halim, M., & Rios-Solis, L. (2021). Recent advances in fed-batch microscale bioreactor design. Biotechnology advances, 107888. https://doi.org/10.1016/j.biotechadv.2021.107888
Teworte, Sarah, et al. "Recent advances in fed-batch microscale bioreactor design." Biotechnology advances vol. (2021): 107888. doi: https://doi.org/10.1016/j.biotechadv.2021.107888
Teworte S, Malcı K, Walls LE, Halim M, Rios-Solis L. Recent advances in fed-batch microscale bioreactor design. Biotechnol Adv. 2021 Dec 16;107888. doi: 10.1016/j.biotechadv.2021.107888. Epub 2021 Dec 16. PMID: 34923075.
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Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Madrasi K, Das R, Mohmmadabdul H, Lin L, Hyman BT, Lauffenburger DA, Albers MW, Rissman RA, Burke JM, Apgar JF, Wille L, Gruenbaum L, Hua F.
PMID: 33938131
Alzheimers Dement. 2021 Sep;17(9):1487-1498. doi: 10.1002/alz.12312. Epub 2021 May 02.

INTRODUCTION: Despite strong evidence linking amyloid beta (Aβ) to Alzheimer's disease, most clinical trials have shown no clinical efficacy for reasons that remain unclear. To understand why, we developed a quantitative systems pharmacology (QSP) model for seven therapeutics: aducanumab,...

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Madrasi K, Das R, Mohmmadabdul H, et al. Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease. Alzheimers Dement. 2021;17(9):1487-1498doi: 10.1002/alz.12312.
Madrasi, K., Das, R., Mohmmadabdul, H., Lin, L., Hyman, B. T., Lauffenburger, D. A., Albers, M. W., Rissman, R. A., Burke, J. M., Apgar, J. F., Wille, L., Gruenbaum, L., & Hua, F. (2021). Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, 17(9), 1487-1498. https://doi.org/10.1002/alz.12312
Madrasi, Kumpal, et al. "Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 17,9 (2021): 1487-1498. doi: https://doi.org/10.1002/alz.12312
Madrasi K, Das R, Mohmmadabdul H, Lin L, Hyman BT, Lauffenburger DA, Albers MW, Rissman RA, Burke JM, Apgar JF, Wille L, Gruenbaum L, Hua F. Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease. Alzheimers Dement. 2021 Sep;17(9):1487-1498. doi: 10.1002/alz.12312. Epub 2021 May 02. PMID: 33938131; PMCID: PMC8478725.
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ASO Visual Abstract: The Impact of Radiotherapy Delay in Breast-Conservation Patients Not Receiving Chemotherapy and the Rationale for Dichotomizing the Radiation Oncology Time-Dependent Standard into Two Quality Measures.

Annals of surgical oncology

Bleicher RJ, Moran MS, Ruth K, Edge SB, Dietz JM, Wilke LG, Stearns V, Kurtzman SH, Klein J, Yao KA.
PMID: 34346019
Ann Surg Oncol. 2021 Dec;28:572-573. doi: 10.1245/s10434-021-10535-8.

No abstract available.

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Bleicher RJ, Moran MS, Ruth K, et al. ASO Visual Abstract: The Impact of Radiotherapy Delay in Breast-Conservation Patients Not Receiving Chemotherapy and the Rationale for Dichotomizing the Radiation Oncology Time-Dependent Standard into Two Quality Measures. Ann Surg Oncol. 2021;28:572-573doi: 10.1245/s10434-021-10535-8.
Bleicher, R. J., Moran, M. S., Ruth, K., Edge, S. B., Dietz, J. M., Wilke, L. G., Stearns, V., Kurtzman, S. H., Klein, J., & Yao, K. A. (2021). ASO Visual Abstract: The Impact of Radiotherapy Delay in Breast-Conservation Patients Not Receiving Chemotherapy and the Rationale for Dichotomizing the Radiation Oncology Time-Dependent Standard into Two Quality Measures. Annals of surgical oncology, 28572-573. https://doi.org/10.1245/s10434-021-10535-8
Bleicher, Richard J, et al. "ASO Visual Abstract: The Impact of Radiotherapy Delay in Breast-Conservation Patients Not Receiving Chemotherapy and the Rationale for Dichotomizing the Radiation Oncology Time-Dependent Standard into Two Quality Measures." Annals of surgical oncology vol. 28 (2021): 572-573. doi: https://doi.org/10.1245/s10434-021-10535-8
Bleicher RJ, Moran MS, Ruth K, Edge SB, Dietz JM, Wilke LG, Stearns V, Kurtzman SH, Klein J, Yao KA. ASO Visual Abstract: The Impact of Radiotherapy Delay in Breast-Conservation Patients Not Receiving Chemotherapy and the Rationale for Dichotomizing the Radiation Oncology Time-Dependent Standard into Two Quality Measures. Ann Surg Oncol. 2021 Dec;28:572-573. doi: 10.1245/s10434-021-10535-8. PMID: 34346019.
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Showing 265 to 274 of 274 entries