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Showing 25 to 36 of 229 entries
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Personalized Medicine-Current and Emerging Predictive and Prognostic Biomarkers in Colorectal Cancer.

Cancers

Koulis C, Yap R, Engel R, Jardé T, Wilkins S, Solon G, Shapiro JD, Abud H, McMurrick P.
PMID: 32231042
Cancers (Basel). 2020 Mar 28;12(4). doi: 10.3390/cancers12040812.

Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide and is heterogeneous both morphologically and molecularly. In an era of personalized medicine, the greatest challenge is to predict individual response to therapy and distinguish patients likely to...

The electron affinity of astatine.

Nature communications

Leimbach D, Karls J, Guo Y, Ahmed R, Ballof J, Bengtsson L, Boix Pamies F, Borschevsky A, Chrysalidis K, Eliav E, Fedorov D, Fedosseev V, Forstner O, Galland N, Garcia Ruiz RF, Granados C, Heinke R, Johnston K, Koszorus A, Köster U, Kristiansson MK, Liu Y, Marsh B, Molkanov P, Pašteka LF, Ramos JP, Renault E, Reponen M, Ringvall-Moberg A, Rossel RE, Studer D, Vernon A, Warbinek J, Welander J, Wendt K, Wilkins S, Hanstorp D, Rothe S.
PMID: 32733029
Nat Commun. 2020 Jul 30;11(1):3824. doi: 10.1038/s41467-020-17599-2.

One of the most important properties influencing the chemical behavior of an element is the electron affinity (EA). Among the remaining elements with unknown EA is astatine, where one of its isotopes,

Dairying enabled Early Bronze Age Yamnaya steppe expansions.

Nature

Wilkin S, Ventresca Miller A, Fernandes R, Spengler R, Taylor WT, Brown DR, Reich D, Kennett DJ, Culleton BJ, Kunz L, Fortes C, Kitova A, Kuznetsov P, Epimakhov A, Zaibert VF, Outram AK, Kitov E, Khokhlov A, Anthony D, Boivin N.
PMID: 34526723
Nature. 2021 Oct;598(7882):629-633. doi: 10.1038/s41586-021-03798-4. Epub 2021 Sep 15.

During the Early Bronze Age, populations of the western Eurasian steppe expanded across an immense area of northern Eurasia. Combined archaeological and genetic evidence supports widespread Early Bronze Age population movements out of the Pontic-Caspian steppe that resulted in...

Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors.

Cell reports

Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP.
PMID: 34233187
Cell Rep. 2021 Jul 06;36(1):109310. doi: 10.1016/j.celrep.2021.109310.

Yes-associated protein 1 (YAP1) regulates cell plasticity during liver injury, regeneration, and cancer, but its role in liver development is unknown. We detect YAP1 activity in biliary cells and in cells at the hepatobiliary bifurcation in single-cell RNA sequencing...

Experiences of patient-led chronic pain peer support groups after pain management programmes: A qualitative study.

Pain medicine (Malden, Mass.)

Farr M, Brant H, Patel R, Linton MJ, Ambler N, Vyas S, Wedge H, Watkins S, Horwood J.
PMID: 34180996
Pain Med. 2021 Jun 26; doi: 10.1093/pm/pnab189. Epub 2021 Jun 26.

OBJECTIVE: A qualitative study of patients' experiences and the impacts of peer support groups that patients maintained after UK NHS group pain management programmes (PMPs).DESIGN: Long-term impacts of group PMPs remain unclear, with indications that positive effects can fade....

Intravital imaging reveals inflammation as a dominant pathophysiology of age-related hepatovascular changes.

American journal of physiology. Cell physiology

Vats R, Li Z, Ju EM, Dubey RK, Kaminski TW, Watkins S, Pradhan-Sundd T.
PMID: 34986022
Am J Physiol Cell Physiol. 2022 Jan 05; doi: 10.1152/ajpcell.00408.2021. Epub 2022 Jan 05.

Aging is the most significant risk factor for the majority of chronic diseases, including liver disease. The cellular, molecular, and pathophysiological mechanisms that promote age-induced hepatovascular changes are unknown due to our inability to visualize changes in liver pathophysiology...

Apparatus for skidding sensitivity testing of energetic materials.

The Review of scientific instruments

Hewitt AT, Lee RJ, Watkins S, Brinkman J, Stephens JC, Dickens JC, Neuber AA.
PMID: 34243458
Rev Sci Instrum. 2021 Apr 01;92(4):045101. doi: 10.1063/5.0043825.

A remote-operated apparatus for testing the detonation sensitivity of energetic materials is detailed. Using an air ram and rotating disk, the normal force and transverse velocity of the impact plane are controlled independently, enabling the exploration of varying impact...

New Variants of Squash Mosaic Viruses Detected in Human Fecal Samples.

Microorganisms

Villanova F, Marcatti R, Bertanhe M, Morais VDS, Milagres FAP, Brustulin R, Araújo ELL, Tahmasebi R, Witkin SS, Deng X, Delwart E, Sabino EC, Abreu-Junior CH, Leal É, Costa ACD.
PMID: 34206387
Microorganisms. 2021 Jun 22;9(7). doi: 10.3390/microorganisms9071349.

Squash mosaic virus (SqMV) is a phytovirus that infects great diversity of plants worldwide. In Brazil, the SqMV has been identified in the states of Ceará, Maranhão, Piauí, Rio Grande do Norte, and Tocantins. The presence of non-pathogenic viruses...

Response.

Chest

Rubin J, Hallowell RW, Witkin AS, Shelton K, Raz Y.
PMID: 34872691
Chest. 2021 Dec;160(6):e681-e682. doi: 10.1016/j.chest.2021.08.048.

No abstract available.

Post-traumatic stress disorder and its association with stroke and stroke risk factors: A literature review.

Neurobiology of stress

Perkins JD, Wilkins SS, Kamran S, Shuaib A.
PMID: 34026954
Neurobiol Stress. 2021 Apr 25;14:100332. doi: 10.1016/j.ynstr.2021.100332. eCollection 2021 May.

Stroke is a major cause of mortality and disability globally that has multiple risk factors. A risk factor that has recently gained more attention is post-traumatic stress disorder (PTSD). Literature searches were carried out for updated PTSD information and...

An exploratory study of associations with spontaneous preterm birth in primigravid pregnant women with a normal cervical length.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Sarmento SGP, Moron AF, Forney LJ, Hatanaka AR, Carvalho FHC, França MS, K Hamamoto T, Mattar R, Linhares IM, Minis E, Sañudo A, Sabino E, Rudge MVC, Witkin SS.
PMID: 33517811
J Matern Fetal Neonatal Med. 2021 Feb 01;1-6. doi: 10.1080/14767058.2021.1879786. Epub 2021 Feb 01.

BACKGROUND: Predictors of spontaneous preterm birth in primigravid women remain undetermined.AIM: We evaluated whether biomarkers in vaginal secretions and/or differences in the dominant bacterium in the vaginal microbiome predicted the risk for spontaneous preterm birth in primigravid women with...

A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development.

ACS central science

Li Y, Tenchov R, Smoot J, Liu C, Watkins S, Zhou Q.
PMID: 34056083
ACS Cent Sci. 2021 Apr 28;7(4):512-533. doi: 10.1021/acscentsci.1c00120. Epub 2021 Mar 29.

This report examines various vaccine platforms including inactivated vaccines, protein-based vaccines, viral vector vaccines, and nucleic acid (DNA or mRNA) vaccines, and their ways of producing immunogens in cells.

Showing 25 to 36 of 229 entries