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Showing 9985 to 9996 of 23947 entries
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Biological and epigenetic alterations of mitochondria involved in cellular replicative and hydrogen peroxide-induced premature senescence of human embryonic lung fibroblasts.

Ecotoxicology and environmental safety

Wang Y, Gao J, Wu F, Lai C, Li Y, Zhang G, Peng X, Yu S, Yang J, Wang W, Zhang W, Yang X.
PMID: 33845364
Ecotoxicol Environ Saf. 2021 Apr 09;216:112204. doi: 10.1016/j.ecoenv.2021.112204. Epub 2021 Apr 09.

The mitoepigenetic modifications may be closely related to cellular fate. Both the replicative and hydrogen peroxide (H

The analysis and identification of charred suspected tea remains unearthed from Warring State Period Tomb.

Scientific reports

Jiang J, Lu G, Wang Q, Wei S.
PMID: 34400663
Sci Rep. 2021 Aug 16;11(1):16557. doi: 10.1038/s41598-021-95393-w.

Recently, a bowl containing charred suspected tea remains unearthed from the early stage of Warring States period tomb in Zoucheng City, Shandong Province, China. To identify the remains is significant for understanding the origin of tea and tea drinking...

Initial fluid resuscitation (30 mL/kg) in patients with septic shock: More or less?.

The American journal of emergency medicine

Wang HL, Shao J, Liu WL, Wu F, Chen HB, Zheng RQ, Chen QH.
PMID: 34428728
Am J Emerg Med. 2021 Dec;50:309-315. doi: 10.1016/j.ajem.2021.08.016. Epub 2021 Aug 10.

OBJECTIVES: The 2018 Surviving Sepsis Campaign (SSC) recommends rapid administration of 30 mL/kg crystalloid fluids for hypotension or lactate ≥4 mmol/L in patients with septic shock; however, there is limited evidence to support this recommendation. The purpose of this...

LncRNA SNHG8 Promotes Proliferation and Inhibits Apoptosis of Diffuse Large B-Cell Lymphoma .

Frontiers in oncology

Yu B, Wang B, Wu Z, Wu C, Ling J, Gao X, Zeng H.
PMID: 33816305
Front Oncol. 2021 Mar 19;11:650287. doi: 10.3389/fonc.2021.650287. eCollection 2021.

Long-chain non-coding RNAs (LncRNAs) are expressed in diffuse large B-cell lymphoma (DLBCL) tissues and have played a regulatory role in DLBCL with a cancer-promoting effect. In this study, the role of LncRNA SNHG8 in the regulation of DLBCL cells...

Optimal dose of erenumab for preventive treatment of episodic migraine: a systematic review and meta-analysis.

Current neuropharmacology

Yang Y, Chen M, Wu D, Sun Y, Jiang F, Chen Z, Wang Z.
PMID: 34429056
Curr Neuropharmacol. 2021 Aug 22; doi: 10.2174/1570159X19666210823104916. Epub 2021 Aug 22.

BACKGROUND: Erenumab is a novel monoclonal calcitonin gene-related peptide receptor antibody that is used for the preventive treatment of migraine.OBJECTIVES: To evaluate overall safety and efficacy and dose-response relationship of erenumab in patients with episodic migraine and patients with...

The effect of lipocalin-2 (LCN2) on apoptosis: a proteomics analysis study in an LCN2 deficient mouse model.

BMC genomics

Wu D, Wang X, Han Y, Wang Y.
PMID: 34903175
BMC Genomics. 2021 Dec 13;22(1):892. doi: 10.1186/s12864-021-08211-y.

BACKGROUND: Recent studies have shown that lipocalin-2 (LCN2) has multiple functions involved in various biological and pathological processes including energy homeostasis, cancer, inflammation, and apoptosis. We aimed to investigate the effect of LCN2 on apoptosis that influences the pathogenetic...

Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia.

Blood

Niu X, Rothe K, Chen M, Grasedieck S, Li R, Nam SE, Zhang X, Novakovskiy GE, Ahn YH, Maksakova I, Lai S, Zhang H, Yan J, Liu H, Zhao Y, Wu D, Ge Y, Wasserman WW, Rouhi A, Kuchenbauer F, Yip CK, Zhang Z, Jiang X.
PMID: 33786587
Blood. 2021 Jul 01;137(26):3641-3655. doi: 10.1182/blood.2020007651.

The abundance of genetic abnormalities and phenotypic heterogeneities in acute myeloid leukemia (AML) poses significant challenges to the development of improved treatments. Here, we demonstrated that a key growth arrest-specific gene 6/AXL axis is highly activated in cells from...

High-efficiency cascade CdS/CdSe quantum dot-sensitized solar cells based on hierarchical tetrapod-like ZnO nanoparticles.

Physical chemistry chemical physics : PCCP

Cheng HM, Huang KY, Lee KM, Yu P, Lin SC, Huang JH, Wu CG, Tang J.
PMID: 22825982
Phys Chem Chem Phys. 2012 Oct 21;14(39):13539-48. doi: 10.1039/c2cp41760j.

Quantum dot-sensitized solar cells (QDSCs) constructed using cascade CdS/CdSe sensitizers and the novel tetrapod-like ZnO nanoparticles have been fabricated. The cascade co-sensitized QDSCs manifested good electron transfer dynamics and overall power conversion efficiency, compared to single CdS- or CdSe-sensitized...

MCR Expression Conferring Varied Fitness Costs on Host Bacteria and Affecting Bacteria Virulence.

Antibiotics (Basel, Switzerland)

Li W, Liu Z, Yin W, Yang L, Qiao L, Song S, Ling Z, Zheng R, Wu C, Wang Y, Shen J.
PMID: 34356793
Antibiotics (Basel). 2021 Jul 19;10(7). doi: 10.3390/antibiotics10070872.

Since the first report of the plasmid-mediated, colistin-resistant gene,

Effect of PRM1201 Combined With Adjuvant Chemotherapy on Preventing Recurrence and Metastasis of Stage III Colon Cancer: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Frontiers in oncology

Jia R, Liu N, Cai G, Zhang Y, Xiao H, Zhou L, Ji Q, Zhao L, Zeng P, Liu H, Huo J, Yue X, Zhang Y, Wu C, Sun X, Feng Y, Liu H, Liu H, Han Z, Lai Y, Zhang Y, Han G, Gong H, Wang Y, Li Q.
PMID: 33747930
Front Oncol. 2021 Mar 03;11:618793. doi: 10.3389/fonc.2021.618793. eCollection 2021.

BACKGROUND: Chemotherapy is the standard adjuvant treatment for colon cancer. Chinese herbal formula PRM1201 improves the efficacy of chemotherapy when used in combination with Cetuximab or Bevacizumab in patients with metastatic colorectal cancer. This study aims to explore the...

Thermo-sensitive micelles extend therapeutic potential for febrile seizures.

Signal transduction and targeted therapy

Wu D, Tang Y, Li W, You Y, Shi J, Xu C, Du Y, Chen Z, Wang Y.
PMID: 34385416
Signal Transduct Target Ther. 2021 Aug 13;6(1):296. doi: 10.1038/s41392-021-00638-9.

No abstract available.

Aerial Drone: an Effective Tool to Teach Information Technology and Cybersecurity through Project Based Learning to Minority High School Students in the U.S.

TechTrends : for leaders in education & training

Bhuyan J, Wu F, Thomas C, Koong K, Won Hur J, Wang CH.
PMID: 34396368
TechTrends. 2020 Nov;64(6):899-910. doi: 10.1007/s11528-020-00502-7. Epub 2020 Apr 22.

This paper describes the design, implementation, and results of an NSF funded Summer Academy from 2016 to 2018, which engaged, on an annual basis, 30 to 60 rising 10th and 11th grade high school science students in an innovative,...

Showing 9985 to 9996 of 23947 entries