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Showing 61 to 72 of 72 entries
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Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities.

Journal for immunotherapy of cancer

Christodoulou I, Ho WJ, Marple A, Ravich JW, Tam A, Rahnama R, Fearnow A, Rietberg C, Yanik S, Solomou EE, Varadhan R, Koldobskiy MA, Bonifant CL.
PMID: 34896980
J Immunother Cancer. 2021 Dec;9(12). doi: 10.1136/jitc-2021-003894.

BACKGROUND: The prognosis of patients with recurrent/refractory acute myelogenous leukemia (AML) remains poor and cell-based immunotherapies hold promise to improve outcomes. Natural Killer (NK) cells can elicit an antileukemic response via a repertoire of activating receptors that bind AML...

Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn's Disease and Ulcerative Colitis.

Frontiers in immunology

Khalili H, Malik S, Ananthakrishnan AN, Garber JJ, Higuchi LM, Joshi A, Peloquin J, Richter JM, Stewart KO, Curhan GC, Awasthi A, Yajnik V, Chan AT.
PMID: 28003811
Front Immunol. 2016 Dec 07;7:554. doi: 10.3389/fimmu.2016.00554. eCollection 2016.

BACKGROUND: Recent animal studies have identified that dietary salt intake may modify the risk and progression of autoimmune disorders through modulation of the IL-23/TMETHODS: We conducted a prospective study of U.S. women enrolled in the Nurses' Health Study (NHS)...

Zero-energy modes, charge conjugation, and fermion number.

Physical review. D, Particles and fields

Sudarshan EC, Yajnik UA.
PMID: 9956837
Phys Rev D Part Fields. 1986 Mar 15;33(6):1830-1832. doi: 10.1103/physrevd.33.1830.

No abstract available.

Phase transition induced by cosmic strings.

Physical review. D, Particles and fields

Yajnik UA.
PMID: 9957283
Phys Rev D Part Fields. 1986 Aug 15;34(4):1237-1240. doi: 10.1103/physrevd.34.1237.

No abstract available.

Observation of Magnetic Radial Vortex Nucleation in a Multilayer Stack with Tunable Anisotropy.

Scientific reports

Karakas V, Gokce A, Habiboglu AT, Arpaci S, Ozbozduman K, Cinar I, Yanik C, Tomasello R, Tacchi S, Siracusano G, Carpentieri M, Finocchio G, Hauet T, Ozatay O.
PMID: 29739995
Sci Rep. 2018 May 08;8(1):7180. doi: 10.1038/s41598-018-25392-x.

Recently discovered exotic magnetic configurations, namely magnetic solitons appearing in the presence of bulk or interfacial Dzyaloshinskii-Moriya Interaction (i-DMI), have excited scientists to explore their potential applications in emerging spintronic technologies such as race-track magnetic memory, spin logic, radio...

Metagenomic Characterization of Microbial Communities .

Cellular and molecular gastroenterology and hepatology

Pedamallu CS, Bhatt AS, Bullman S, Fowler S, Freeman SS, Durand J, Jung J, Duke F, Manzo V, Cai D, Ananthakrishnan A, Ojesina AI, Ramachandran A, Gevers D, Xavier RJ, Bhan AK, Meyerson M, Yajnik V.
PMID: 28174737
Cell Mol Gastroenterol Hepatol. 2016 May 26;2(5):563-566.e5. doi: 10.1016/j.jcmgh.2016.05.011. eCollection 2016 Sep.

BACKGROUND & AIMS: Microbial dysbiosis and aberrant host-microbe interactions in the gut are believed to contribute to the development and progression of Crohn's disease (CD). Microbiome studies in CD typically have focused on microbiota in feces or superficial mucosal...

Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power.

Nature

Locke AE, Steinberg KM, Chiang CWK, Service SK, Havulinna AS, Stell L, Pirinen M, Abel HJ, Chiang CC, Fulton RS, Jackson AU, Kang CJ, Kanchi KL, Koboldt DC, Larson DE, Nelson J, Nicholas TJ, Pietilä A, Ramensky V, Ray D, Scott LJ, Stringham HM, Vangipurapu J, Welch R, Yajnik P, Yin X, Eriksson JG, Ala-Korpela M, Järvelin MR, Männikkö M, Laivuori H, Dutcher SK, Stitziel NO, Wilson RK, Hall IM, Sabatti C, Palotie A, Salomaa V, Laakso M, Ripatti S, Boehnke M, Freimer NB.
PMID: 31686056
Nature. 2019 Nov;575(7783):E4. doi: 10.1038/s41586-019-1726-x.

An Amendment to this paper has been published and can be accessed via a link at the top of the paper.

Subgroups of patients with young-onset type 2 diabetes in India reveal insulin deficiency as a major driver.

Diabetologia

Prasad RB, Asplund O, Shukla SR, Wagh R, Kunte P, Bhat D, Parekh M, Shah M, Phatak S, Käräjämäki A, Datta A, Kakati S, Tuomi T, Saboo B, Ahlqvist E, Groop L, Yajnik CS.
PMID: 34689214
Diabetologia. 2022 Jan;65(1):65-78. doi: 10.1007/s00125-021-05543-y. Epub 2021 Oct 23.

AIM/HYPOTHESIS: Five subgroups were described in European diabetes patients using a data driven machine learning approach on commonly measured variables. We aimed to test the applicability of this phenotyping in Indian individuals with young-onset type 2 diabetes.METHODS: We applied...

Vitamin B12 and Folate Markers Are Associated with Insulin Resistance During the Third Trimester of Pregnancy in South Asian Women, Living in the United Kingdom, with Gestational Diabetes and Normal Glucose Tolerance.

The Journal of nutrition

Sobczyńska-Malefora A, Yajnik CS, Harrington DJ, Hitman GA, Finer S.
PMID: 34601603
J Nutr. 2022 Jan 11;152(1):163-170. doi: 10.1093/jn/nxab352.

BACKGROUND: Gestational diabetes mellitus (GDM) can adversely affect the health of the developing fetus. Women of South Asian origin are particularly at risk of developing GDM. Insulin resistance (IR) contributes to the etiology of GDM, and although studies have...

Maternal Glucose and LDL-Cholesterol Levels Are Related to Placental Leptin Gene Methylation, and, Together With Nutritional Factors, Largely Explain a Higher Methylation Level Among Ethnic South Asians.

Frontiers in endocrinology

Sletner L, Moen AEF, Yajnik CS, Lekanova N, Sommer C, Birkeland KI, Jenum AK, Böttcher Y.
PMID: 35002980
Front Endocrinol (Lausanne). 2021 Dec 24;12:809916. doi: 10.3389/fendo.2021.809916. eCollection 2021.

BACKGROUND: Leptin, mainly secreted by fat cells, plays a core role in the regulation of appetite and body weight, and has been proposed as a mediator of metabolic programming. During pregnancy leptin is also secreted by the placenta, as...

Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities.

Journal for immunotherapy of cancer

Christodoulou I, Ho WJ, Marple A, Ravich JW, Tam A, Rahnama R, Fearnow A, Rietberg C, Yanik S, Solomou EE, Varadhan R, Koldobskiy MA, Bonifant CL.
PMID: 34896980
J Immunother Cancer. 2021 Dec;9(12). doi: 10.1136/jitc-2021-003894.

BACKGROUND: The prognosis of patients with recurrent/refractory acute myelogenous leukemia (AML) remains poor and cell-based immunotherapies hold promise to improve outcomes. Natural Killer (NK) cells can elicit an antileukemic response via a repertoire of activating receptors that bind AML...

Efficacy of B.

Food and nutrition bulletin

Yajnik C, Kasture S, Kantikar V, Lubree H, Bhat D, Raut D, Memane N, Bhalerao A, Ladkat R, Yajnik P, Tomar S, Limaye T, Phatak S.
PMID: 34189981
Food Nutr Bull. 2021 Dec;42(4):480-489. doi: 10.1177/03795721211025448. Epub 2021 Jun 30.

BACKGROUND: Dietary vitamin BOBJECTIVE: To study efficacy of BMETHODS: Two double-blind, placebo-controlled directly observed therapy randomized controlled trials were conducted for 120 days: (1) Healthy children (10-13 years) were fed nutrient bar fortified with BRESULTS: We randomized 164 children...

Showing 61 to 72 of 72 entries