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Showing 9985 to 9996 of 25873 entries
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Role of peroral endoscopic myotomy in geriatric patients with achalasia: a systematic review and meta-analysis.

Digestive diseases (Basel, Switzerland)

Zhong C, Huang S, Xia H, Tan S, Lü M, Peng Y, Tang X.
PMID: 33752208
Dig Dis. 2021 Mar 22; doi: 10.1159/000516024. Epub 2021 Mar 22.

BACKGROUND: Peroral endoscopic myotomy (POEM) is a particularly attractive intervention for achalasia. Presently, POEM has been reported to be effective and safe for achalasia in geriatric patients. Herein, this systematic review was conducted to explore the role of POEM...

Alternative Lengthening of Telomeres Phenotype Predicts Progression Risk in Noninsulinomas in a Chinese Cohort.

Neuroendocrinology

Ban X, Mo S, Lu Z, Jia C, Shao H, Yan J, Chang X, Mao X, Wu Y, Zhang Y, Fan X, Yu S, Chen J.
PMID: 34348341
Neuroendocrinology. 2021 Jul 12; doi: 10.1159/000518413. Epub 2021 Jul 12.

INTRODUCTION: Recent studies have suggested that alternative lengthening of telomeres (ALT) is associated with metastasis and poor survival in pancreatic neuroendocrine tumors (PanNETs). This study evaluated whether this association is applicable to Chinese patients as well as the potential...

Translational and post-translational control of human naïve versus primed pluripotency.

iScience

Chen C, Zhang X, Wang Y, Chen X, Chen W, Dan S, She S, Hu W, Dai J, Hu J, Cao Q, Liu Q, Huang Y, Qin B, Kang B, Wang YJ.
PMID: 35005567
iScience. 2021 Dec 17;25(1):103645. doi: 10.1016/j.isci.2021.103645. eCollection 2022 Jan 21.

Deciphering the regulatory network for human naive and primed pluripotency is of fundamental theoretical and applicable significance. Here, by combining quantitative proteomics, phosphoproteomics, and acetylproteomics analyses, we revealed RNA processing and translation as the most differentially regulated processes between...

National Analysis of Oropharyngeal Salivary Gland Malignancies Treated With Transoral Robotic Surgery.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Bollig CA, Wang K, Llerena P, Puram SV, Pipkorn PJ, Jackson RS, Stubbs VC.
PMID: 34311621
Otolaryngol Head Neck Surg. 2021 Jul 27;1945998211031161. doi: 10.1177/01945998211031161. Epub 2021 Jul 27.

OBJECTIVES: (1) To compare perioperative outcomes and overall survival of patients with oropharyngeal salivary gland malignancies (OPSGMs) treated with transoral robotic surgery (TORS) versus other approaches. (2) To identify clinical factors associated with a robotic surgical approach.STUDY DESIGN: Retrospective...

Structured 3D linear space-time light bullets by nonlocal nanophotonics.

Light, science & applications

Guo C, Xiao M, Orenstein M, Fan S.
PMID: 34341327
Light Sci Appl. 2021 Aug 02;10(1):160. doi: 10.1038/s41377-021-00595-6.

We propose the generation of 3D linear light bullets propagating in free space using a single passive nonlocal optical surface. The nonlocal nanophotonics can generate space-time coupling without any need for bulky pulse-shaping and spatial modulation techniques. Our approach...

Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease.

Regenerative biomaterials

Zhu J, Yang S, Yang Y, Yao T, Liu G, Fan S, Zhao H, Cui F, Wang X, Jiang G, Fang X.
PMID: 33732497
Regen Biomater. 2021 Jan 09;8(1):rbaa051. doi: 10.1093/rb/rbaa051. eCollection 2021 Feb 01.

Kümmell disease (KD) causes serious vertebral body collapse in patients. However, only a few case reports have been conducted and the number of patients with KD investigated was limited. Additionally, the frequently used poly(methyl methacrylate) (PMMA) bone cement for...

Best Supportive Care .

Frontiers in oncology

Li H, Xue R, Yang X, Han S, Yang W, Song X, Zhang X, Cao J, Jia S, Wang W, Lian J.
PMID: 33732638
Front Oncol. 2021 Mar 01;11:568568. doi: 10.3389/fonc.2021.568568. eCollection 2021.

BACKGROUND: WBRT and systemic chemotherapy are the mainstay treatments for small-cell lung cancer (SCLC) brain metastases (BM). However, current recommendations are mainly based on evidence from retrospective analyses. A recent randomized trial found no benefits from WBRT compared with...

Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO-1 pathways.

Immunity, inflammation and disease

Xu C, Song Y, Wang Z, Jiang J, Piao Y, Li L, Jin S, Li L, Zhu L, Yan G.
PMID: 34342160
Immun Inflamm Dis. 2021 Dec;9(4):1406-1417. doi: 10.1002/iid3.490. Epub 2021 Aug 02.

INTRODUCTION: Pterostilbene (Pts) may be used for allergic asthma treatment. The AMPK/Sirt1 and Nrf2/HO-1 pathways are potential targets for asthma treatement. However, the relationship between Pts and AMPK/Sirt1 and Nrf2/HO-1 pathways in asthma is unclear. Herein, we aim to...

Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects.

Journal of nanobiotechnology

Yan J, Zhan X, Zhang Z, Chen K, Wang M, Sun Y, He B, Liang Y.
PMID: 34876145
J Nanobiotechnology. 2021 Dec 07;19(1):412. doi: 10.1186/s12951-021-01164-0.

Recently, DNA nanostructures with vast application potential in the field of biomedicine, especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have attracted interest worldwide due to their high stability, excellent biocompatibility, and simplicity of modification. TDN could...

The correlation between the STOP-Bang score and oxygen saturation during spinal anesthesia with dexmedetomidine sedation.

Anesthesia and pain medicine

Yun M, Kim J, Ryu S, Han S, Shin Y.
PMID: 34289296
Anesth Pain Med (Seoul). 2021 Jul;16(3):305-311. doi: 10.17085/apm.21011. Epub 2021 Jul 15.

BACKGROUND: The STOP-Bang questionnaire is a simple screening tool with high sensitivity for the detection of severe obstructive sleep apnea. Predicting airway obstruction would allow the safe management of sedative patients to prevent intraoperative hypoxia. This study was designed...

New Insights Into the Intricacies of Proneural Gene Regulation in the Embryonic and Adult Cerebral Cortex.

Frontiers in molecular neuroscience

Oproescu AM, Han S, Schuurmans C.
PMID: 33658912
Front Mol Neurosci. 2021 Feb 15;14:642016. doi: 10.3389/fnmol.2021.642016. eCollection 2021.

Historically, the mammalian brain was thought to lack stem cells as no new neurons were found to be made in adulthood. That dogma changed ∼25 years ago with the identification of neural stem cells (NSCs) in the adult rodent...

Diagnosis of Fibrosis Using Blood Markers and Logistic Regression in Southeast Asian Patients With Non-alcoholic Fatty Liver Disease.

Frontiers in medicine

Sang C, Yan H, Chan WK, Zhu X, Sun T, Chang X, Xia M, Sun X, Hu X, Gao X, Jia W, Bian H, Chen T, Xie G.
PMID: 33708783
Front Med (Lausanne). 2021 Feb 23;8:637652. doi: 10.3389/fmed.2021.637652. eCollection 2021.

Non-alcoholic fatty liver disease (NAFLD) is one of the main causes of fibrosis. Liver biopsy remains the gold standard for the confirmation of fibrosis in NAFLD patients. Effective and non-invasive diagnosis of advanced fibrosis is essential to disease surveillance...

Showing 9985 to 9996 of 25873 entries