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Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.

Pharmacological research

Yin A, Feng M, Zhang L, Cheng Z, Li Y, Qian L.
PMID: 34808368
Pharmacol Res. 2021 Nov 19;175:105988. doi: 10.1016/j.phrs.2021.105988. Epub 2021 Nov 19.

Myocardial ischemia-reperfusion (I/R) is a severe disease，but its underlying mechanism is not fully elucidated and no effective clinical treatment is available. Utilizing intracellular peptidomics, we identified a novel native peptide PDRL23A (Peptide Derived from RPL23A), that is intimately related...

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Yin A, Feng M, Zhang L, et al. Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion. Pharmacol Res. 2021;175:105988doi: 10.1016/j.phrs.2021.105988.
Yin, A., Feng, M., Zhang, L., Cheng, Z., Li, Y., & Qian, L. (2021). Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion. Pharmacological research, 175105988. https://doi.org/10.1016/j.phrs.2021.105988
Yin, Anwen, et al. "Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion." Pharmacological research vol. 175 (2021): 105988. doi: https://doi.org/10.1016/j.phrs.2021.105988
Yin A, Feng M, Zhang L, Cheng Z, Li Y, Qian L. Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion. Pharmacol Res. 2021 Nov 19;175:105988. doi: 10.1016/j.phrs.2021.105988. Epub 2021 Nov 19. PMID: 34808368.
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The role of pathological tau in synaptic dysfunction in Alzheimer's diseases.

Translational neurodegeneration

Wu M, Zhang M, Yin X, Chen K, Hu Z, Zhou Q, Cao X, Chen Z, Liu D.
PMID: 34753506
Transl Neurodegener. 2021 Nov 10;10(1):45. doi: 10.1186/s40035-021-00270-1.

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau accumulation in the brain. Synaptic dysfunction, an important pathological hallmark in AD, is recognized as the main cause of...

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Wu M, Zhang M, Yin X, et al. The role of pathological tau in synaptic dysfunction in Alzheimer's diseases. Transl Neurodegener. 2021;10(1):45doi: 10.1186/s40035-021-00270-1.
Wu, M., Zhang, M., Yin, X., Chen, K., Hu, Z., Zhou, Q., Cao, X., Chen, Z., & Liu, D. (2021). The role of pathological tau in synaptic dysfunction in Alzheimer's diseases. Translational neurodegeneration, 10(1), 45. https://doi.org/10.1186/s40035-021-00270-1
Wu, Moxin, et al. "The role of pathological tau in synaptic dysfunction in Alzheimer's diseases." Translational neurodegeneration vol. 10,1 (2021): 45. doi: https://doi.org/10.1186/s40035-021-00270-1
Wu M, Zhang M, Yin X, Chen K, Hu Z, Zhou Q, Cao X, Chen Z, Liu D. The role of pathological tau in synaptic dysfunction in Alzheimer's diseases. Transl Neurodegener. 2021 Nov 10;10(1):45. doi: 10.1186/s40035-021-00270-1. PMID: 34753506; PMCID: PMC8579533.
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One-step removal of high-concentration arsenic from wastewater to form Johnbaumite using arsenic-bearing gypsum.

Journal of hazardous materials

Sun X, Mao M, Lu K, Hu Q, Liu W, Lin Z.
PMID: 34753651
J Hazard Mater. 2021 Oct 23;127585. doi: 10.1016/j.jhazmat.2021.127585. Epub 2021 Oct 23.

High-level arsenic-containing wastewater (HAW) causes serious environmental pollution. Chemical precipitation is the most widely used technology for treating HAW. However, chemical precipitation generates huge amounts of hazardous solid wastes, which leads to secondary pollution. In this work, an efficient...

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Sun X, Mao M, Lu K, et al. One-step removal of high-concentration arsenic from wastewater to form Johnbaumite using arsenic-bearing gypsum. J Hazard Mater. 2021;127585doi: 10.1016/j.jhazmat.2021.127585.
Sun, X., Mao, M., Lu, K., Hu, Q., Liu, W., & Lin, Z. (2021). One-step removal of high-concentration arsenic from wastewater to form Johnbaumite using arsenic-bearing gypsum. Journal of hazardous materials, 127585. https://doi.org/10.1016/j.jhazmat.2021.127585
Sun, Xin, et al. "One-step removal of high-concentration arsenic from wastewater to form Johnbaumite using arsenic-bearing gypsum." Journal of hazardous materials vol. (2021): 127585. doi: https://doi.org/10.1016/j.jhazmat.2021.127585
Sun X, Mao M, Lu K, Hu Q, Liu W, Lin Z. One-step removal of high-concentration arsenic from wastewater to form Johnbaumite using arsenic-bearing gypsum. J Hazard Mater. 2021 Oct 23;127585. doi: 10.1016/j.jhazmat.2021.127585. Epub 2021 Oct 23. PMID: 34753651.
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Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China.

Annals of palliative medicine

Chen K, Mao Z, Jin Z, Gao G, Bian C.
PMID: 33474945
Ann Palliat Med. 2021 Jan;10(1):392-403. doi: 10.21037/apm-20-2262. Epub 2021 Jan 13.

BACKGROUND: The technique of sampling is a particularly important aspect of sampling surveys, and the method of determining sample size is the key link in sampling technique. However, a sample size determination method for complex sampling surveys of sensitive...

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Chen K, Mao Z, Jin Z, et al. Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China. Ann Palliat Med. 2021;10(1):392-403doi: 10.21037/apm-20-2262.
Chen, K., Mao, Z., Jin, Z., Gao, G., & Bian, C. (2021). Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China. Annals of palliative medicine, 10(1), 392-403. https://doi.org/10.21037/apm-20-2262
Chen, Kejin, et al. "Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China." Annals of palliative medicine vol. 10,1 (2021): 392-403. doi: https://doi.org/10.21037/apm-20-2262
Chen K, Mao Z, Jin Z, Gao G, Bian C. Application of a randomized response technique for the sensitive question survey in female sex workers in Xichang, China. Ann Palliat Med. 2021 Jan;10(1):392-403. doi: 10.21037/apm-20-2262. Epub 2021 Jan 13. PMID: 33474945.
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Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products.

Molecular medicine (Cambridge, Mass.)

Shoaib M, Kim N, Choudhary RC, Yin T, Shinozaki K, Becker LB, Kim J.
PMID: 34689738
Mol Med. 2021 Oct 24;27(1):135. doi: 10.1186/s10020-021-00397-x.

BACKGROUND: Cardiac arrest (CA) results in loss of blood circulation to all tissues leading to oxygen and metabolite dysfunction. Return of blood flow and oxygen during resuscitative efforts is the beginning of reperfusion injury and is marked by the...

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Shoaib M, Kim N, Choudhary RC, et al. Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products. Mol Med. 2021;27(1):135doi: 10.1186/s10020-021-00397-x.
Shoaib, M., Kim, N., Choudhary, R. C., Yin, T., Shinozaki, K., Becker, L. B., & Kim, J. (2021). Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products. Molecular medicine (Cambridge, Mass.), 27(1), 135. https://doi.org/10.1186/s10020-021-00397-x
Shoaib, Muhammad, et al. "Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products." Molecular medicine (Cambridge, Mass.) vol. 27,1 (2021): 135. doi: https://doi.org/10.1186/s10020-021-00397-x
Shoaib M, Kim N, Choudhary RC, Yin T, Shinozaki K, Becker LB, Kim J. Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products. Mol Med. 2021 Oct 24;27(1):135. doi: 10.1186/s10020-021-00397-x. PMID: 34689738; PMCID: PMC8543965.
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Modification of α-Cyclodextrin Polyrotaxanes by ATRP for Conjugating Drug and Prolonging Blood Circulation.

ACS biomaterials science & engineering

Zhang J, Zhang L, Li S, Yin C, Li C, Wu W, Jiang X.
PMID: 33445266
ACS Biomater Sci Eng. 2018 Jun 11;4(6):1963-1968. doi: 10.1021/acsbiomaterials.7b00464. Epub 2017 Aug 25.

To enhance the water solubility of α-cyclodextrin (CD) polyrotaxanes (PRs) and achieve effective drug loading, we polymerized 2-hydroxyethyl methacrylate and 2-tert-butoxy-N-(2-(methacryloyloxy)ethyl)-N,N-dimethyl-2-oxoethanaminium successively from a α-CD-PR-based macroinitiator by a two-step ATRP followed by cleaving the

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Zhang J, Zhang L, Li S, et al. Modification of α-Cyclodextrin Polyrotaxanes by ATRP for Conjugating Drug and Prolonging Blood Circulation. ACS Biomater Sci Eng. 2017;4(6):1963-1968doi: 10.1021/acsbiomaterials.7b00464.
Zhang, J., Zhang, L., Li, S., Yin, C., Li, C., Wu, W., & Jiang, X. (2018). Modification of α-Cyclodextrin Polyrotaxanes by ATRP for Conjugating Drug and Prolonging Blood Circulation. ACS biomaterials science & engineering, 4(6), 1963-1968. https://doi.org/10.1021/acsbiomaterials.7b00464
Zhang, Jialiang, et al. "Modification of α-Cyclodextrin Polyrotaxanes by ATRP for Conjugating Drug and Prolonging Blood Circulation." ACS biomaterials science & engineering vol. 4,6 (2018): 1963-1968. doi: https://doi.org/10.1021/acsbiomaterials.7b00464
Zhang J, Zhang L, Li S, Yin C, Li C, Wu W, Jiang X. Modification of α-Cyclodextrin Polyrotaxanes by ATRP for Conjugating Drug and Prolonging Blood Circulation. ACS Biomater Sci Eng. 2018 Jun 11;4(6):1963-1968. doi: 10.1021/acsbiomaterials.7b00464. Epub 2017 Aug 25. PMID: 33445266.
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Swine unconventional T cells.

Developmental and comparative immunology

Wu M, Jiang Q, Nazmi A, Yin J, Yang G.
PMID: 34863955
Dev Comp Immunol. 2021 Dec 03;128:104330. doi: 10.1016/j.dci.2021.104330. Epub 2021 Dec 03.

Pigs are important domestic livestock and a comprehensive understanding of their immune system is critical to improve swine vaccine efficacy. Pig models represent an excellent animal model for immunological studies because of their anatomical and physiological similarities to humans....

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Wu M, Jiang Q, Nazmi A, et al. Swine unconventional T cells. Dev Comp Immunol. 2021;128:104330doi: 10.1016/j.dci.2021.104330.
Wu, M., Jiang, Q., Nazmi, A., Yin, J., & Yang, G. (2021). Swine unconventional T cells. Developmental and comparative immunology, 128104330. https://doi.org/10.1016/j.dci.2021.104330
Wu, Miaomiao, et al. "Swine unconventional T cells." Developmental and comparative immunology vol. 128 (2021): 104330. doi: https://doi.org/10.1016/j.dci.2021.104330
Wu M, Jiang Q, Nazmi A, Yin J, Yang G. Swine unconventional T cells. Dev Comp Immunol. 2021 Dec 03;128:104330. doi: 10.1016/j.dci.2021.104330. Epub 2021 Dec 03. PMID: 34863955.
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Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis.

Frontiers in surgery

He X, Yin S, Liu H, Lu R, Kernstine K, Gerber DE, Xie Y, Yang DM.
PMID: 34722619
Front Surg. 2021 Oct 13;8:649531. doi: 10.3389/fsurg.2021.649531. eCollection 2021.

No abstract available.

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He X, Yin S, Liu H, et al. Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis. Front Surg. 2021;8:649531doi: 10.3389/fsurg.2021.649531.
He, X., Yin, S., Liu, H., Lu, R., Kernstine, K., Gerber, D. E., Xie, Y., & Yang, D. M. (2021). Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis. Frontiers in surgery, 8649531. https://doi.org/10.3389/fsurg.2021.649531
He, Xiaopeng, et al. "Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis." Frontiers in surgery vol. 8 (2021): 649531. doi: https://doi.org/10.3389/fsurg.2021.649531
He X, Yin S, Liu H, Lu R, Kernstine K, Gerber DE, Xie Y, Yang DM. Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis. Front Surg. 2021 Oct 13;8:649531. doi: 10.3389/fsurg.2021.649531. eCollection 2021. PMID: 34722619; PMCID: PMC8549861.
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Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium.

ACS biomaterials science & engineering

Yin F, Zhu Y, Wang Y, Qin J.
PMID: 33445346
ACS Biomater Sci Eng. 2018 May 14;4(5):1908-1915. doi: 10.1021/acsbiomaterials.8b00160. Epub 2018 Mar 29.

Brain organoids derived from human induced pluripotent stem cells (hiPSCs) are three-dimensional in vitro models with near-physiological cellular composition and structural organization, which is representative of the developing human brain. They provide an ideal experimental system for the investigation...

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Yin F, Zhu Y, Wang Y, et al. Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium. ACS Biomater Sci Eng. 2018;4(5):1908-1915doi: 10.1021/acsbiomaterials.8b00160.
Yin, F., Zhu, Y., Wang, Y., & Qin, J. (2018). Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium. ACS biomaterials science & engineering, 4(5), 1908-1915. https://doi.org/10.1021/acsbiomaterials.8b00160
Yin, Fangchao, et al. "Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium." ACS biomaterials science & engineering vol. 4,5 (2018): 1908-1915. doi: https://doi.org/10.1021/acsbiomaterials.8b00160
Yin F, Zhu Y, Wang Y, Qin J. Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium. ACS Biomater Sci Eng. 2018 May 14;4(5):1908-1915. doi: 10.1021/acsbiomaterials.8b00160. Epub 2018 Mar 29. PMID: 33445346.
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S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells.

Frontiers in oncology

Meng L, Tang Q, Zhao J, Wang Z, Wei L, Wei Q, Yin L, Luo S, Song J.
PMID: 34150664
Front Oncol. 2021 Jun 03;11:691705. doi: 10.3389/fonc.2021.691705. eCollection 2021.

Multiple myeloma (MM) is a lethal hematological malignancy characterized by abundant myeloid cells in the microenvironment that fuel tumor progression. But the mechanism by which myeloid cells support myeloma cells has not been fully explored. We aimed to examine...

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Meng L, Tang Q, Zhao J, et al. S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells. Front Oncol. 2021;11:691705doi: 10.3389/fonc.2021.691705.
Meng, L., Tang, Q., Zhao, J., Wang, Z., Wei, L., Wei, Q., Yin, L., Luo, S., & Song, J. (2021). S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells. Frontiers in oncology, 11691705. https://doi.org/10.3389/fonc.2021.691705
Meng, Lingzhang, et al. "S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells." Frontiers in oncology vol. 11 (2021): 691705. doi: https://doi.org/10.3389/fonc.2021.691705
Meng L, Tang Q, Zhao J, Wang Z, Wei L, Wei Q, Yin L, Luo S, Song J. S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells. Front Oncol. 2021 Jun 03;11:691705. doi: 10.3389/fonc.2021.691705. eCollection 2021. PMID: 34150664; PMCID: PMC8210673.
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Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer.

Cancer management and research

Tang Y, Cui Y, Li LL, Guan YP, Feng DF, Yin BB, Liang XF, Yin J, Jiang R, Liang J, Sun YH, Wang J.
PMID: 34754244
Cancer Manag Res. 2021 Nov 02;13:8241-8255. doi: 10.2147/CMAR.S329963. eCollection 2021.

PURPOSE: To evaluate the dynamics of early serum tumour markers (STMs) and the neutrophil-to-lymphocyte ratio (NLR) to predict clinical efficacy and prognosis of advanced non-small-cell lung cancer (NSCLC) patients who received programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1)...

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Tang Y, Cui Y, Li LL, et al. Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer. Cancer Manag Res. 2021;13:8241-8255doi: 10.2147/CMAR.S329963.
Tang, Y., Cui, Y., Li, L. L., Guan, Y. P., Feng, D. F., Yin, B. B., Liang, X. F., Yin, J., Jiang, R., Liang, J., Sun, Y. H., & Wang, J. (2021). Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer. Cancer management and research, 138241-8255. https://doi.org/10.2147/CMAR.S329963
Tang, Yin, et al. "Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer." Cancer management and research vol. 13 (2021): 8241-8255. doi: https://doi.org/10.2147/CMAR.S329963
Tang Y, Cui Y, Li LL, Guan YP, Feng DF, Yin BB, Liang XF, Yin J, Jiang R, Liang J, Sun YH, Wang J. Dynamics of Early Serum Tumour Markers and Neutrophil-to-Lymphocyte Ratio Predict Response to PD-1/PD-L1 Inhibitors in Advanced Non-Small-Cell Lung Cancer. Cancer Manag Res. 2021 Nov 02;13:8241-8255. doi: 10.2147/CMAR.S329963. eCollection 2021. PMID: 34754244; PMCID: PMC8572022.
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Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy.

Disease markers

Wang A, Chu H, Jin Z, Jia Q, Zhu B.
PMID: 34754345
Dis Markers. 2021 Oct 31;2021:9453692. doi: 10.1155/2021/9453692. eCollection 2021.

Immune checkpoint inhibitor (ICI) responses vary, and biomarkers for predicting responders are urgently needed. Growing evidence points to the association between programmed cell death protein ligand 2 (PDL2) and ICI benefits, while clinical evidences were lacking. Thus, we consolidated...

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Wang A, Chu H, Jin Z, et al. Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy. Dis Markers. 2021;2021:9453692doi: 10.1155/2021/9453692.
Wang, A., Chu, H., Jin, Z., Jia, Q., & Zhu, B. (2021). Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy. Disease markers, 20219453692. https://doi.org/10.1155/2021/9453692
Wang, Aoyun, et al. "Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy." Disease markers vol. 2021 (2021): 9453692. doi: https://doi.org/10.1155/2021/9453692
Wang A, Chu H, Jin Z, Jia Q, Zhu B. Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy. Dis Markers. 2021 Oct 31;2021:9453692. doi: 10.1155/2021/9453692. eCollection 2021. PMID: 34754345; PMCID: PMC8572643.
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Showing 9985 to 9996 of 28406 entries