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Showing 133 to 140 of 140 entries
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Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m.

Heliyon

Abner JJ, Franklin JL, Clement MA, Hinger SA, Allen RM, Liu X, Kellner S, Wu J, Karijolich J, Liu Q, Vickers KC, Dedon P, Weaver AM, Coffey RJ, Patton JG.
PMID: 34934837
Heliyon. 2021 Dec 02;7(12):e08519. doi: 10.1016/j.heliyon.2021.e08519. eCollection 2021 Dec.

Extracellular vesicles (EVs) are capable of transferring cargo from donor to recipient cells, but precisely how cargo content is regulated for export is mostly unknown. For miRNA cargo, we previously showed that when compared to isogenic colorectal cancer (CRC)...

The Acquisition of the .

Frontiers in microbiology

Hammerl JA, Göllner C, Jäckel C, Swidan F, Gutmann H, Strauch E.
PMID: 34867877
Front Microbiol. 2021 Nov 15;12:754464. doi: 10.3389/fmicb.2021.754464. eCollection 2021.

Most strains of

Association of serum vitamin D levels with disease severity, systemic inflammation, prior lung function loss and exacerbations in a cohort of patients with chronic obstructive pulmonary disease (COPD).

Journal of thoracic disease

Jorde I, Stegemann-Koniszewski S, Papra K, Föllner S, Lux A, Schreiber J, Lücke E.
PMID: 34277053
J Thorac Dis. 2021 Jun;13(6):3597-3609. doi: 10.21037/jtd-20-3221.

BACKGROUND: Vitamin D deficiency has been associated with chronic disorders including chronic obstructive pulmonary disease (COPD) but the relationships with inflammation, exacerbations and disease progression remain unclear.METHODS: In this monocentric cross-sectional observational study we analyzed the disease status, systemic...

Strategies to Avoid Artifacts in Mass Spectrometry-Based Epitranscriptome Analyses.

Angewandte Chemie (International ed. in English)

Kaiser S, Byrne SR, Ammann G, Asadi Atoi P, Borland K, Brecheisen R, DeMott MS, Gehrke T, Hagelskamp F, Heiss M, Yoluç Y, Liu L, Zhang Q, Dedon PC, Cao B, Kellner S.
PMID: 34339593
Angew Chem Int Ed Engl. 2021 Oct 25;60(44):23885-23893. doi: 10.1002/anie.202106215. Epub 2021 Sep 29.

In this report, we perform structure validation of recently reported RNA phosphorothioate (PT) modifications, a new set of epitranscriptome marks found in bacteria and eukaryotes including humans. By comparing synthetic PT-containing diribonucleotides with native species in RNA hydrolysates by...

Influence of Electronic Structure Modeling and Junction Structure on First-Principles Chiral Induced Spin Selectivity.

Journal of chemical theory and computation

Zöllner MS, Saghatchi A, Mujica V, Herrmann C.
PMID: 33167619
J Chem Theory Comput. 2020 Dec 08;16(12):7357-7371. doi: 10.1021/acs.jctc.0c00621. Epub 2020 Nov 09.

We have carried out a comprehensive study of the influence of electronic structure modeling and junction structure description on the first-principles calculation of the spin polarization in molecular junctions caused by the chiral induced spin selectivity (CISS) effect. We...

Transitioning to community-based mental health service delivery: opportunities for Ukraine.

Journal of market access & health policy

Quirke E, Suvalo O, Sukhovii O, Zöllner Y.
PMID: 33235691
J Mark Access Health Policy. 2020 Nov 12;8(1):1843288. doi: 10.1080/20016689.2020.1843288.

No abstract available.

[Using emergency department routine data for the surveillance of suicide attempts and psychiatric emergencies].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz

Schlump C, Thom J, Boender TS, Wagner B, Diercke M, Kocher T, Ullrich A, Grabenhenrich L, Greiner F, Zöllner R, Mauz E, Schranz M.
PMID: 34889967
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Jan;65(1):30-39. doi: 10.1007/s00103-021-03467-x. Epub 2021 Dec 10.

BACKGROUND: The occurrence of suicide attempts is a key indicator of the population's mental health and therefore belongs in the domain of Mental Health Surveillance at the Robert Koch Institute. No data source is currently being used systematically for...

Modulation of intrinsic inhibitory checkpoints using nano-carriers to unleash NK cell activity.

EMBO molecular medicine

Biber G, Sabag B, Raiff A, Ben-Shmuel A, Puthenveetil A, Benichou JIC, Jubany T, Levy M, Killner S, Barda-Saad M.
PMID: 34725941
EMBO Mol Med. 2021 Nov 02;e14073. doi: 10.15252/emmm.202114073. Epub 2021 Nov 02.

Natural killer (NK) cells provide a powerful weapon mediating immune defense against viral infections, tumor growth, and metastatic spread. NK cells demonstrate great potential for cancer immunotherapy; they can rapidly and directly kill cancer cells in the absence of...

Showing 133 to 140 of 140 entries