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Showing 25 to 36 of 189 entries
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Operational Innovation in the Provision of Pediatric Extracorporeal Membrane Oxygenation for Multisystem Inflammatory Syndrome in Children.

Health security

Naber CE, Fernandes ND, Lahoud-Rahme M, Doucette D, Goldstein AM, Yager PH, Cummings BM, Carroll RW.
PMID: 35020494
Health Secur. 2022 Jan 11; doi: 10.1089/hs.2021.0119. Epub 2022 Jan 11.

Treatment of multisystem inflammatory syndrome in children (MIS-C) can require significant critical care resources. Our aim is to alert mixed pediatric and adult hospitals worldwide of the possibility that pediatric and adult patients may simultaneously require cannulation to extracorporeal...

Semi-quantitative assessment of ischemia with rubidium-82 PET myocardial perfusion imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Borren NM, Gerritse TJ, Ottervanger JP, Mouden M, Timmer JR, van Dalen JA, Jager PL, van Dijk JD.
PMID: 34970710
J Nucl Cardiol. 2021 Dec 30; doi: 10.1007/s12350-021-02884-4. Epub 2021 Dec 30.

PURPOSE: Semi-quantitative scores can be used as an adjunct to visual assessment in rubidium-82 positron emission tomography (METHODS: We included 108 patients who underwent RESULTS: 41 (38%) Normal scans, and 67 (62%) scans with ischemia and/or an irreversible defect...

Advances in Kriging-Based Autonomous X-Ray Scattering Experiments.

Scientific reports

Noack MM, Doerk GS, Li R, Fukuto M, Yager KG.
PMID: 31992725
Sci Rep. 2020 Jan 28;10(1):1325. doi: 10.1038/s41598-020-57887-x.

Autonomous experimentation is an emerging paradigm for scientific discovery, wherein measurement instruments are augmented with decision-making algorithms, allowing them to autonomously explore parameter spaces of interest. We have recently demonstrated a generalized approach to autonomous experimental control, based on...

Dendrimer Ligand Directed Nanoplate Assembly.

ACS nano

Elbert KC, Vo T, Krook NM, Zygmunt W, Park J, Yager KG, Composto RJ, Glotzer SC, Murray CB.
PMID: 31756073
ACS Nano. 2019 Dec 24;13(12):14241-14251. doi: 10.1021/acsnano.9b07348. Epub 2019 Dec 04.

Many studies on nanocrystal (NC) self-assembly into ordered superlattices have focused mainly on attractive forces between the NCs, whereas the role of organic ligands on anisotropic NCs is only in its infancy. Herein, we report the use of a...

Flavonoid Deficiency Disrupts Redox Homeostasis and Terpenoid Biosynthesis in Glandular Trichomes of Tomato.

Plant physiology

Sugimoto K, Zager JJ, Aubin BS, Lange BM, Howe GA.
PMID: 34668550
Plant Physiol. 2021 Oct 20; doi: 10.1093/plphys/kiab488. Epub 2021 Oct 20.

Glandular trichomes are epidermal structures that provide a first line of chemical defense against arthropod herbivores and other biotic threats. The most conspicuous structure on leaves of cultivated tomato (Solanum lycopersicum) is the type-VI glandular trichome (tVI-GT), which accumulates...

Patient-Reported Adverse Events of Radiopharmaceuticals: A Prospective Study of 1002 Patients.

Drug safety

Schreuder N, Jacobs NA, Jager PL, Kosterink JGW, van Puijenbroek EP.
PMID: 33094442
Drug Saf. 2021 Feb;44(2):211-222. doi: 10.1007/s40264-020-01006-2. Epub 2020 Oct 22.

INTRODUCTION: Adverse events of radiopharmaceuticals may be underreported or remain undetected. Patients can provide information about these adverse events to enable healthcare professionals to detect, understand, and manage them more efficiently.OBJECTIVE: In this study, we aimed to (a) determine...

Autonomous materials discovery driven by Gaussian process regression with inhomogeneous measurement noise and anisotropic kernels.

Scientific reports

Noack MM, Doerk GS, Li R, Streit JK, Vaia RA, Yager KG, Fukuto M.
PMID: 33077759
Sci Rep. 2020 Oct 19;10(1):17663. doi: 10.1038/s41598-020-74394-1.

A majority of experimental disciplines face the challenge of exploring large and high-dimensional parameter spaces in search of new scientific discoveries. Materials science is no exception; the wide variety of synthesis, processing, and environmental conditions that influence material properties...

Effect of temporal sampling protocols on myocardial blood flow measurements using Rubidium-82 PET.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Koenders SS, van Dijk JD, Jager PL, Mouden M, Tegelaar AG, Slump CH, van Dalen JA.
PMID: 33655444
J Nucl Cardiol. 2021 Mar 02; doi: 10.1007/s12350-021-02555-4. Epub 2021 Mar 02.

BACKGROUND: A variety of temporal sampling protocols is used worldwide to measure myocardial blood flow (MBF). Both the length and number of time frames in these protocols may alter MBF and myocardial flow reserve (MFR) measurements. We aimed to...

Mental Illness and Stigma in Surgical Residencies-An Unspoken Truth.

JAMA surgery

Fu WW, Gauger PG, Newman EA.
PMID: 33052384
JAMA Surg. 2021 Feb 01;156(2):117-118. doi: 10.1001/jamasurg.2020.2965.

No abstract available.

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Nature genetics

Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Thorleifsson G, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W, Amin N, Bakshi A, Bergmann S, Bjornsdottir G, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner AJ, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Liewald DC, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Råback L, Quaye L, Räikkönen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bültmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hyppönen E, Iacono WG, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Keltikangas-Järvinen L, Kraft P, Kubzansky LD, Lehtimäki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sørensen TI, Spector TD, Starr JM, Stefansson K, Steptoe A, Terracciano A, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D.
PMID: 27463399
Nat Genet. 2016 Jul 27;48(8):970. doi: 10.1038/ng0816-970c.

No abstract available.

Encorafenib/binimetinib for the treatment of BRAF-mutant advanced, unresectable, or metastatic melanoma: design, development, and potential place in therapy.

OncoTargets and therapy

Sun J, Zager JS, Eroglu Z.
PMID: 30588020
Onco Targets Ther. 2018 Dec 14;11:9081-9089. doi: 10.2147/OTT.S171693. eCollection 2018.

Major advances in the understanding of the pathophysiology of melanoma have led to a new era of melanoma treatment with targeted therapy and immunotherapies. Since 2011, four new classes of medications with unique mechanisms of action have been approved,...

Correction to: Merkel Cell Carcinoma Outcomes: Does AJCC8 Underestimate Survival?.

Annals of surgical oncology

Farley CR, Perez MC, Soelling SJ, Delman KA, Harit A, Wuthrick EJ, Messina JL, Sondak VK, Zager JS, Lowe MC.
PMID: 32699930
Ann Surg Oncol. 2020 Dec;27:983. doi: 10.1245/s10434-020-08871-2.

C.R. Farley and M.C. Perez contributed equally to this publication and are co-first authors. J.S. Zager and M.C. Lowe contributed equally to this publication and are co-corresponding authors.

Showing 25 to 36 of 189 entries