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Showing 3457 to 3467 of 3467 entries
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Lemnalemnanes A-C, Three Rare Rearranged Sesquiterpenoids from the Soft Corals .

Organic letters

Han X, Wang Q, Luo X, Tang X, Wang Z, Zhang D, Cao S, Li P, Li G.
PMID: 34904837
Org Lett. 2022 Jan 14;24(1):11-15. doi: 10.1021/acs.orglett.1c03386. Epub 2021 Dec 14.

Three novel sesquiterpenoids, lemnalemnanes A-C (

Clinical Effects of the Combination of Rhytidectomy and Temporomandibular Joint Disc Repositioning Surgery.

The Journal of craniofacial surgery

Zhang DD, Lee LM, Zhu YM, Cheng HN, Yao W, Deng YQ.
PMID: 34387262
J Craniofac Surg. 2021 Aug 13; doi: 10.1097/SCS.0000000000008075. Epub 2021 Aug 13.

OBJECTIVE: This study aims to investigate the clinical effects of the combination of rhytidectomy and temporomandibular joint (TMJ) disc repositioning surgery in internal derangement (ID) stage IV-V and facial aging patients.METHODS: Eighteen facial aging with bilateral ID IV-V patients...

Immunotherapy of Cancer by Targeting Regulatory T cells.

International immunopharmacology

Chen BJ, Zhao JW, Zhang DH, Zheng AH, Wu GQ.
PMID: 35008005
Int Immunopharmacol. 2022 Jan 07;104:108469. doi: 10.1016/j.intimp.2021.108469. Epub 2022 Jan 07.

Regulatory T (Treg) cells maintain immune homeostasis by inhibiting abnormal/overactive immune responses to both autogenic and nonautogenic antigens. Treg cells play an important role in immune tolerance, autoimmune diseases, infectious diseases, organ transplantation, and tumor diseases. Treg cells have...

Complete genome analysis of a nege-like virus in aphids (Astegopteryx formosana).

Archives of virology

Zhang XD, Lu G, Ye ZX, Chen JP, Zhang CX, Li JM.
PMID: 34762150
Arch Virol. 2022 Jan;167(1):267-270. doi: 10.1007/s00705-021-05299-1. Epub 2021 Nov 11.

Negeviruses are a group of insect-specific viruses that have a wide geographic distribution and broad host range. In recent years, nege-like viruses have been discovered in aphids of various genera of the family Aphididae, including Aphis, Rhopalosiphum, Sitobion, and...

Towards the Highly Efficient Synthesis and Selective Methylation of C(sp.

Angewandte Chemie (International ed. in English)

Du XS, Zhang DW, Guo Y, Li J, Han Y, Chen CF.
PMID: 33783080
Angew Chem Int Ed Engl. 2021 Jun 01;60(23):13021-13028. doi: 10.1002/anie.202102701. Epub 2021 May 06.

An approach to the highly efficient synthesis of C(sp3)-bridged [6]cycloparaphenylenes (C[6]CPPs) from fluoren[3]arenes (F[3]As) was developed. Consequently, F[3]As as a new kind of macrocyclic arenes were synthesized. Followed by the demethylation, triflation and intramolecular aryl-aryl coupling reactions, C[6]CPPs were...

The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer.

Scientific reports

Reich LA, Moerland JA, Leal AS, Zhang D, Carapellucci S, Lockwood B, Jurutka PW, Marshall PA, Wagner CE, Liby KT.
PMID: 34997154
Sci Rep. 2022 Jan 07;12(1):293. doi: 10.1038/s41598-021-04415-0.

Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cutaneous T cell lymphoma, is the only FDA-approved rexinoid. Bexarotene...

Cytosolic Delivery of Thiolated Neoantigen Nano-Vaccine Combined with Immune Checkpoint Blockade to Boost Anti-Cancer T Cell Immunity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang D, Lin Z, Wu M, Cai Z, Zheng Y, He L, Li Z, Zhou J, Sun L, Chen G, Zeng Y, Li J, Liu J, Yang H, Liu X.
PMID: 33747739
Adv Sci (Weinh). 2021 Jan 29;8(6):2003504. doi: 10.1002/advs.202003504. eCollection 2021 Mar.

Although tumor-specific neoantigen-based cancer vaccines hold tremendous potential, it still faces low cross-presentation associated with severe degradation via endocytosis pathway. Herein, a thiolated nano-vaccine allowing direct cytosolic delivery of neoantigen and Toll like receptor 9 agonist CpG-ODN is developed....

Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.

Theranostics

Sun H, Zeng J, Miao Z, Lei KC, Huang C, Hu L, Su SM, Chan UI, Miao K, Zhang X, Zhang A, Guo S, Chen S, Meng Y, Deng M, Hao W, Lei H, Lin Y, Yang Z, Tang D, Wong KH, Zhang XD, Xu X, Deng CX.
PMID: 34815798
Theranostics. 2021 Oct 25;11(20):9967-9987. doi: 10.7150/thno.63995. eCollection 2021.

No abstract available.

DriverSubNet: A Novel Algorithm for Identifying Cancer Driver Genes by Subnetwork Enrichment Analysis.

Frontiers in genetics

Zhang D, Bin Y.
PMID: 33679866
Front Genet. 2021 Feb 19;11:607798. doi: 10.3389/fgene.2020.607798. eCollection 2020.

Identification of driver genes from mass non-functional passenger genes in cancers is still a critical challenge. Here, an effective and no parameter algorithm, named DriverSubNet, is presented for detecting driver genes by effectively mining the mutation and gene expression...

Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti-inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines.

Frontiers in microbiology

Tang Q, Yang C, Li W, Zhang Y, Wang X, Wang W, Ma Z, Zhang D, Jin Y, Lin D.
PMID: 34456884
Front Microbiol. 2021 Aug 11;12:684650. doi: 10.3389/fmicb.2021.684650. eCollection 2021.

The incidence of zoonotic

Optimum synthesis of cactus-inspired SERS substrate with high roughness for paraquat detection.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Chen W, Li C, Yu Z, Song Y, Zhang X, Ni D, Zhang, Liang P.
PMID: 34896679
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Dec 03;268:120703. doi: 10.1016/j.saa.2021.120703. Epub 2021 Dec 03.

Paraquat is a highly effective herbicide and widely used in agricultural production. However, paraquat residue is harmful for human health and can cause irreversible hazard. Thus, it is crucial for monitoring of paraquat residues. In this paper, an efficient...

Showing 3457 to 3467 of 3467 entries